Pamela Dyson | University of Oxford (original) (raw)

Papers by Pamela Dyson

Upsala Journal of Medical Sciences, 2021

Background: The fatty acid (FA) composition of blood can be used as an objective biomarker of die... more Background: The fatty acid (FA) composition of blood can be used as an objective biomarker of dietary FA intake. It remains unclear how the nutritional state influences the FA composition of plasma lipid fractions, and thus their usefulness as biomarkers in a non-fasted state. Objectives: To investigate the associations between palmitate, oleate and linoleate in plasma lipid fractions and self-reported dietary FA intake, and assess the influence of meal consumption on the relative abundance of these FA in plasma lipid fractions (i.e. triglyceride [TG], phospholipids [PLs] and cholesterol esters [CEs]). Design: Analysis was performed in plasma samples collected from 49 (34 males and 15 females) participants aged 26–57 years with a body mass index (BMI) between 21.6 and 34.2 kg/m2, all of whom had participated in multiple study visits, thus a pooled cohort of 98 data sets was available for analysis. A subset (n = 25) had undergone nutritional interventions and was therefore used to in...

Advanced Nutrition and Dietetics in Diabetes, 2015

Practical Diabetes, 2021

Mediterranean diets (MDs) are recommended by some authorities for the prevention and management o... more Mediterranean diets (MDs) are recommended by some authorities for the prevention and management of diabetes, although there is some confusion about the definition and components of MDs. This narrative review explores the definition role of MDs in diabetes.

British Journal of Nutrition, 2021

Background In May 2021, the Scientific Advisory Committee on Nutrition (SACN) published a risk as... more Background In May 2021, the Scientific Advisory Committee on Nutrition (SACN) published a risk assessment on lower carbohydrate diets for adults with type 2 diabetes (T2D)(1). The purpose of the report was to review the evidence on ‘low’-carbohydrate diets compared with the current UK government advice on carbohydrate intake for adults with T2D. However, since there is no agreed and widely utilised definition of a ‘low’-carbohydrate diet, comparisons in the report were between lower and higher carbohydrate diets. SACN’s remit is to assess the risks and benefits of nutrients, dietary patterns, food or food components for health by evaluating scientific evidence and to make dietary recommendations for the UK based on its assessment(2). SACN has a public health focus and only considers evidence in healthy populations unless specifically requested to do otherwise. Since the Committee does not usually make recommendations relating to clinical conditions, a joint working group (WG) was es...

Diabetic Medicine, 2017

Dietary interventions for people with diabetes can be complex and are often delivered by dietitia... more Dietary interventions for people with diabetes can be complex and are often delivered by dietitians in non-specialist roles. In 2011, Diabetes UK published a competency framework for dietitians designed to improve the delivery of nutritional advice to all people with diabetes. The aim of this initiative was to design and evaluate a structured training programme to improve diabetes competencies in non-specialist dietitians working in the adult service in Oxfordshire

Non-communicable disease (NCD), including cardiovascular disease, cancer, diabetes and chronic re... more Non-communicable disease (NCD), including cardiovascular disease, cancer, diabetes and chronic respiratory diseases, accounted for over 65.5% of deaths in 2010, with more than 80% of these occurring in low and middle-income countries (LMIC). Approximately 30% of the deaths in LMIC occur prematurely and are largely preventable. NCD is also associated with increased morbidity and reduced quality of life, and it has been estimated that the global economic impact of NCD could total US$47 trillion over the next twenty years, equivalent to 5% of GDP. The causes of NCD have their roots in three major modifiable risk factors; tobacco use, physical inactivity and unhealthy diet and prevention of NCD by addressing these factors at the community level is fast becoming an area of interest. Most authorities, including the United Nations (UN), the World Health Organisation (WHO) and the US Center for Disease Control and Prevention (CDC) recommend evidence-based strategies for lifestyle interventi...

There are a variety of strategies that can be used to induce weight loss in people with diabetes,... more There are a variety of strategies that can be used to induce weight loss in people with diabetes, and evidence suggests that significant weight losses occur with most diets, and that differences between different diets are small and insignificant (Johnston et al, 2014; Naude et al, 2014). To optimise weight loss, it is recommended that primary care practitioners support their patients with a dietary strategy of their choice and agree realistic weight loss targets

Diabetes Care, 2020

OBJECTIVE Debate continues regarding the influence of dietary fats and sugars on the risk of deve... more OBJECTIVE Debate continues regarding the influence of dietary fats and sugars on the risk of developing metabolic diseases, including insulin resistance and nonalcoholic fatty liver disease (NAFLD). We investigated the effect of two eucaloric diets, one enriched with saturated fat (SFA) and the other enriched with free sugars (SUGAR), on intrahepatic triacylglycerol (IHTAG) content, hepatic de novo lipogenesis (DNL), and whole-body postprandial metabolism in overweight males. RESEARCH DESIGN AND METHODS Sixteen overweight males were randomized to consume the SFA or SUGAR diet for 4 weeks before consuming the alternate diet after a 7-week washout period. The metabolic effects of the respective diets on IHTAG content, hepatic DNL, and whole-body metabolism were investigated using imaging techniques and metabolic substrates labeled with stable-isotope tracers. RESULTS Consumption of the SFA diet significantly increased IHTAG by mean ± SEM 39.0 ± 10.0%, while after the SUGAR diet IHTAG ...

Diabetes Care, 2020

OBJECTIVE Debate continues regarding the influence of dietary fats and sugars on the risk of deve... more OBJECTIVE Debate continues regarding the influence of dietary fats and sugars on the risk of developing metabolic diseases, including insulin resistance and nonalcoholic fatty liver disease (NAFLD). We investigated the effect of two eucaloric diets, one enriched with saturated fat (SFA) and the other enriched with free sugars (SUGAR), on intrahepatic triacylglycerol (IHTAG) content, hepatic de novo lipogenesis (DNL), and whole-body postprandial metabolism in overweight males. RESEARCH DESIGN AND METHODS Sixteen overweight males were randomized to consume the SFA or SUGAR diet for 4 weeks before consuming the alternate diet after a 7-week washout period. The metabolic effects of the respective diets on IHTAG content, hepatic DNL, and whole-body metabolism were investigated using imaging techniques and metabolic substrates labeled with stable-isotope tracers. RESULTS Consumption of the SFA diet significantly increased IHTAG by mean ± SEM 39.0 ± 10.0%, while after the SUGAR diet IHTAG ...

Diabetes Therapy, 2018

This article has been co-authored by a patient with type 2 diabetes and a specialist dietitian. H... more This article has been co-authored by a patient with type 2 diabetes and a specialist dietitian. Here they discuss the patient's experience and difficulties with controlling weight and strategies that can help a patient in this situation. The patient discusses how stress and her corresponding comfort eating dampened weight loss progress, and how adopting a lifestyle change aided through group support helped to deal with this. The physician discusses the importance of recognizing the mental and physical challenges faced by patients in this situation.

PloS one, 2015

Non-communicable disease (NCD) is increasing rapidly in low and middle-income countries (LMIC), a... more Non-communicable disease (NCD) is increasing rapidly in low and middle-income countries (LMIC), and is associated with tobacco use, unhealthy diet and physical inactivity. There is little evidence for up-scaled interventions at the population level to reduce risk in LMIC. The Community Interventions for Health (CIH) program was a population-scale community intervention study with comparator population group undertaken in communities in China, India, and Mexico, each with populations between 150,000-250,000. Culturally appropriate interventions were delivered over 18-24 months. Two independent cross-sectional surveys of a stratified sample of adults aged 18-64 years were conducted at baseline and follow-up. A total of 6,194 adults completed surveys at baseline, and 6,022 at follow-up. The proportion meeting physical activity recommendations decreased significantly in the control group (C) (44.1 to 30.2%), but not in the intervention group (I) (38.0 to 36.1%), p<0.001. Those eating...

PloS one, 2015

Non-communicable disease (NCD) is increasing rapidly in low and middle-income countries (LMIC), a... more Non-communicable disease (NCD) is increasing rapidly in low and middle-income countries (LMIC), and is associated with tobacco use, unhealthy diet and physical inactivity. There is little evidence for up-scaled interventions at the population level to reduce risk in LMIC. The Community Interventions for Health (CIH) program was a population-scale community intervention study with comparator population group undertaken in communities in China, India, and Mexico, each with populations between 150,000-250,000. Culturally appropriate interventions were delivered over 18-24 months. Two independent cross-sectional surveys of a stratified sample of adults aged 18-64 years were conducted at baseline and follow-up. A total of 6,194 adults completed surveys at baseline, and 6,022 at follow-up. The proportion meeting physical activity recommendations decreased significantly in the control group (C) (44.1 to 30.2%), but not in the intervention group (I) (38.0 to 36.1%), p<0.001. Those eating...

The Diabetes Educator, 2012

Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 2014

Jiska J. Aardoom Giovanni Abbate-Daga Suzanne Abraham Gianfranco Adami Isabelle Amado Suman Ambwa... more Jiska J. Aardoom Giovanni Abbate-Daga Suzanne Abraham Gianfranco Adami Isabelle Amado Suman Ambwani Drew Anderson Nathalie André Steve Anton Kathleen Ashton D. Atalayer Liv Augestad Rachel Bachner-Melman Matteo Balestrieri Nicole Barbarich-Marsteller Giuseppe Barbaro Rachel Barnes John Batsis Anne Madeleine Bau Daniel F. Becker Yatan Balhara Jessica Bennett Sergio Bernasconi Laird Birmingham Leandro Boer-Martins Ottavio Bosello Terrill Bravender Timothy David Brewerton Paula Brochu Timo Brockmeyer Paul Brunault Marija Burgić-Radmanović Jake M. Burmeister Deborah L. Burnet Luca Busetto Llorenç Caballerı́a Simona Calugi Robert A. Carels Ritalba Caroli Giovanni Casella Gianluca Castelnuovo Marı́a Luisa Catalina Zamora Hellas Cena Julie Chambers I-Chia Chien Angélica de Medeiros Claudino David Clinton Sarah Colby Angelo Compare Eva M. Conceicao Maurice Corcos Paolo Cotrufo Barbara Cresci Philip Crockett Scott Crow Francesca Cuzzocrea Riccardo Dalle Grave Ida Dancyger Federico Dazzi Nicola De Angelis Emilia De Filippo Marcia de Oliveira Otto Leonore M. de Wit Metella Dei Valeria del balzo Maria del Consuelo Escoto Ponce de León Liliana Dell’Osso Daniele Di Pauli Laura Di Renzo Alexandra E. Dingemans Nora E. Durkin Pamela Dyson Francesca Emanuelli Gianpietro Emerenziani Chris Evans Andrea Fabbri Joel Faintuch Secondo Fassino Lisa Fellin Manfred Fichter Maria Luisa Fonte Leng Huat Foo Akihito Fujimori Xiao Gao Rick M. Gardner David Garner Sanne M. Gerards Ata Ghaderi Katrin Giel

Upsala Journal of Medical Sciences, 2021

Background: The fatty acid (FA) composition of blood can be used as an objective biomarker of die... more Background: The fatty acid (FA) composition of blood can be used as an objective biomarker of dietary FA intake. It remains unclear how the nutritional state influences the FA composition of plasma lipid fractions, and thus their usefulness as biomarkers in a non-fasted state. Objectives: To investigate the associations between palmitate, oleate and linoleate in plasma lipid fractions and self-reported dietary FA intake, and assess the influence of meal consumption on the relative abundance of these FA in plasma lipid fractions (i.e. triglyceride [TG], phospholipids [PLs] and cholesterol esters [CEs]). Design: Analysis was performed in plasma samples collected from 49 (34 males and 15 females) participants aged 26–57 years with a body mass index (BMI) between 21.6 and 34.2 kg/m2, all of whom had participated in multiple study visits, thus a pooled cohort of 98 data sets was available for analysis. A subset (n = 25) had undergone nutritional interventions and was therefore used to in...

Advanced Nutrition and Dietetics in Diabetes, 2015

Practical Diabetes, 2021

Mediterranean diets (MDs) are recommended by some authorities for the prevention and management o... more Mediterranean diets (MDs) are recommended by some authorities for the prevention and management of diabetes, although there is some confusion about the definition and components of MDs. This narrative review explores the definition role of MDs in diabetes.

British Journal of Nutrition, 2021

Background In May 2021, the Scientific Advisory Committee on Nutrition (SACN) published a risk as... more Background In May 2021, the Scientific Advisory Committee on Nutrition (SACN) published a risk assessment on lower carbohydrate diets for adults with type 2 diabetes (T2D)(1). The purpose of the report was to review the evidence on ‘low’-carbohydrate diets compared with the current UK government advice on carbohydrate intake for adults with T2D. However, since there is no agreed and widely utilised definition of a ‘low’-carbohydrate diet, comparisons in the report were between lower and higher carbohydrate diets. SACN’s remit is to assess the risks and benefits of nutrients, dietary patterns, food or food components for health by evaluating scientific evidence and to make dietary recommendations for the UK based on its assessment(2). SACN has a public health focus and only considers evidence in healthy populations unless specifically requested to do otherwise. Since the Committee does not usually make recommendations relating to clinical conditions, a joint working group (WG) was es...

Diabetic Medicine, 2017

Dietary interventions for people with diabetes can be complex and are often delivered by dietitia... more Dietary interventions for people with diabetes can be complex and are often delivered by dietitians in non-specialist roles. In 2011, Diabetes UK published a competency framework for dietitians designed to improve the delivery of nutritional advice to all people with diabetes. The aim of this initiative was to design and evaluate a structured training programme to improve diabetes competencies in non-specialist dietitians working in the adult service in Oxfordshire

Non-communicable disease (NCD), including cardiovascular disease, cancer, diabetes and chronic re... more Non-communicable disease (NCD), including cardiovascular disease, cancer, diabetes and chronic respiratory diseases, accounted for over 65.5% of deaths in 2010, with more than 80% of these occurring in low and middle-income countries (LMIC). Approximately 30% of the deaths in LMIC occur prematurely and are largely preventable. NCD is also associated with increased morbidity and reduced quality of life, and it has been estimated that the global economic impact of NCD could total US$47 trillion over the next twenty years, equivalent to 5% of GDP. The causes of NCD have their roots in three major modifiable risk factors; tobacco use, physical inactivity and unhealthy diet and prevention of NCD by addressing these factors at the community level is fast becoming an area of interest. Most authorities, including the United Nations (UN), the World Health Organisation (WHO) and the US Center for Disease Control and Prevention (CDC) recommend evidence-based strategies for lifestyle interventi...

There are a variety of strategies that can be used to induce weight loss in people with diabetes,... more There are a variety of strategies that can be used to induce weight loss in people with diabetes, and evidence suggests that significant weight losses occur with most diets, and that differences between different diets are small and insignificant (Johnston et al, 2014; Naude et al, 2014). To optimise weight loss, it is recommended that primary care practitioners support their patients with a dietary strategy of their choice and agree realistic weight loss targets

Diabetes Care, 2020

OBJECTIVE Debate continues regarding the influence of dietary fats and sugars on the risk of deve... more OBJECTIVE Debate continues regarding the influence of dietary fats and sugars on the risk of developing metabolic diseases, including insulin resistance and nonalcoholic fatty liver disease (NAFLD). We investigated the effect of two eucaloric diets, one enriched with saturated fat (SFA) and the other enriched with free sugars (SUGAR), on intrahepatic triacylglycerol (IHTAG) content, hepatic de novo lipogenesis (DNL), and whole-body postprandial metabolism in overweight males. RESEARCH DESIGN AND METHODS Sixteen overweight males were randomized to consume the SFA or SUGAR diet for 4 weeks before consuming the alternate diet after a 7-week washout period. The metabolic effects of the respective diets on IHTAG content, hepatic DNL, and whole-body metabolism were investigated using imaging techniques and metabolic substrates labeled with stable-isotope tracers. RESULTS Consumption of the SFA diet significantly increased IHTAG by mean ± SEM 39.0 ± 10.0%, while after the SUGAR diet IHTAG ...

Diabetes Care, 2020

OBJECTIVE Debate continues regarding the influence of dietary fats and sugars on the risk of deve... more OBJECTIVE Debate continues regarding the influence of dietary fats and sugars on the risk of developing metabolic diseases, including insulin resistance and nonalcoholic fatty liver disease (NAFLD). We investigated the effect of two eucaloric diets, one enriched with saturated fat (SFA) and the other enriched with free sugars (SUGAR), on intrahepatic triacylglycerol (IHTAG) content, hepatic de novo lipogenesis (DNL), and whole-body postprandial metabolism in overweight males. RESEARCH DESIGN AND METHODS Sixteen overweight males were randomized to consume the SFA or SUGAR diet for 4 weeks before consuming the alternate diet after a 7-week washout period. The metabolic effects of the respective diets on IHTAG content, hepatic DNL, and whole-body metabolism were investigated using imaging techniques and metabolic substrates labeled with stable-isotope tracers. RESULTS Consumption of the SFA diet significantly increased IHTAG by mean ± SEM 39.0 ± 10.0%, while after the SUGAR diet IHTAG ...

Diabetes Therapy, 2018

This article has been co-authored by a patient with type 2 diabetes and a specialist dietitian. H... more This article has been co-authored by a patient with type 2 diabetes and a specialist dietitian. Here they discuss the patient's experience and difficulties with controlling weight and strategies that can help a patient in this situation. The patient discusses how stress and her corresponding comfort eating dampened weight loss progress, and how adopting a lifestyle change aided through group support helped to deal with this. The physician discusses the importance of recognizing the mental and physical challenges faced by patients in this situation.

PloS one, 2015

Non-communicable disease (NCD) is increasing rapidly in low and middle-income countries (LMIC), a... more Non-communicable disease (NCD) is increasing rapidly in low and middle-income countries (LMIC), and is associated with tobacco use, unhealthy diet and physical inactivity. There is little evidence for up-scaled interventions at the population level to reduce risk in LMIC. The Community Interventions for Health (CIH) program was a population-scale community intervention study with comparator population group undertaken in communities in China, India, and Mexico, each with populations between 150,000-250,000. Culturally appropriate interventions were delivered over 18-24 months. Two independent cross-sectional surveys of a stratified sample of adults aged 18-64 years were conducted at baseline and follow-up. A total of 6,194 adults completed surveys at baseline, and 6,022 at follow-up. The proportion meeting physical activity recommendations decreased significantly in the control group (C) (44.1 to 30.2%), but not in the intervention group (I) (38.0 to 36.1%), p<0.001. Those eating...

PloS one, 2015

Non-communicable disease (NCD) is increasing rapidly in low and middle-income countries (LMIC), a... more Non-communicable disease (NCD) is increasing rapidly in low and middle-income countries (LMIC), and is associated with tobacco use, unhealthy diet and physical inactivity. There is little evidence for up-scaled interventions at the population level to reduce risk in LMIC. The Community Interventions for Health (CIH) program was a population-scale community intervention study with comparator population group undertaken in communities in China, India, and Mexico, each with populations between 150,000-250,000. Culturally appropriate interventions were delivered over 18-24 months. Two independent cross-sectional surveys of a stratified sample of adults aged 18-64 years were conducted at baseline and follow-up. A total of 6,194 adults completed surveys at baseline, and 6,022 at follow-up. The proportion meeting physical activity recommendations decreased significantly in the control group (C) (44.1 to 30.2%), but not in the intervention group (I) (38.0 to 36.1%), p<0.001. Those eating...

The Diabetes Educator, 2012

Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 2014

Jiska J. Aardoom Giovanni Abbate-Daga Suzanne Abraham Gianfranco Adami Isabelle Amado Suman Ambwa... more Jiska J. Aardoom Giovanni Abbate-Daga Suzanne Abraham Gianfranco Adami Isabelle Amado Suman Ambwani Drew Anderson Nathalie André Steve Anton Kathleen Ashton D. Atalayer Liv Augestad Rachel Bachner-Melman Matteo Balestrieri Nicole Barbarich-Marsteller Giuseppe Barbaro Rachel Barnes John Batsis Anne Madeleine Bau Daniel F. Becker Yatan Balhara Jessica Bennett Sergio Bernasconi Laird Birmingham Leandro Boer-Martins Ottavio Bosello Terrill Bravender Timothy David Brewerton Paula Brochu Timo Brockmeyer Paul Brunault Marija Burgić-Radmanović Jake M. Burmeister Deborah L. Burnet Luca Busetto Llorenç Caballerı́a Simona Calugi Robert A. Carels Ritalba Caroli Giovanni Casella Gianluca Castelnuovo Marı́a Luisa Catalina Zamora Hellas Cena Julie Chambers I-Chia Chien Angélica de Medeiros Claudino David Clinton Sarah Colby Angelo Compare Eva M. Conceicao Maurice Corcos Paolo Cotrufo Barbara Cresci Philip Crockett Scott Crow Francesca Cuzzocrea Riccardo Dalle Grave Ida Dancyger Federico Dazzi Nicola De Angelis Emilia De Filippo Marcia de Oliveira Otto Leonore M. de Wit Metella Dei Valeria del balzo Maria del Consuelo Escoto Ponce de León Liliana Dell’Osso Daniele Di Pauli Laura Di Renzo Alexandra E. Dingemans Nora E. Durkin Pamela Dyson Francesca Emanuelli Gianpietro Emerenziani Chris Evans Andrea Fabbri Joel Faintuch Secondo Fassino Lisa Fellin Manfred Fichter Maria Luisa Fonte Leng Huat Foo Akihito Fujimori Xiao Gao Rick M. Gardner David Garner Sanne M. Gerards Ata Ghaderi Katrin Giel