Lateral diffusion in a mixture of mobile and immobile particles. A Monte Carlo study (original) (raw)
Abstract
The lateral diffusion coefficient for mixtures of mobile and immobile particles is obtained from Monte Carlo calculations of random walks by mobile tracers in the presence of immobile obstacles on a triangular lattice. The diffusion coefficient of the mobile species is obtained as a function of the area fractions of mobile and immobile species. The results are applied to diffusion of band 3 in the erythrocyte membrane, and indicate that obstruction of diffusion of mobile band 3 by band 3 and glycophorin attached to the membrane skeleton is not sufficient to explain the observed diffusion coefficient.
Selected References
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- Abney J. R., Scalettar B. A., Owicki J. C. Self diffusion of interacting membrane proteins. Biophys J. 1989 May;55(5):817–833. doi: 10.1016/S0006-3495(89)82882-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bennett V. The spectrin-actin junction of erythrocyte membrane skeletons. Biochim Biophys Acta. 1989 Jan 18;988(1):107–121. doi: 10.1016/0304-4157(89)90006-3. [DOI] [PubMed] [Google Scholar]
- Cherry R. J., Bürkli A., Busslinger M., Schneider G., Parish G. R. Rotational diffusion of band 3 proteins in the human erythrocyte membrane. Nature. 1976 Sep 30;263(5576):389–393. doi: 10.1038/263389a0. [DOI] [PubMed] [Google Scholar]
- Clague M. J., Harrison J. P., Cherry R. J. Cytoskeletal restraints of band 3 rotational mobility in human erythrocyte membranes. Biochim Biophys Acta. 1989 May 19;981(1):43–50. doi: 10.1016/0005-2736(89)90080-1. [DOI] [PubMed] [Google Scholar]
- Edholm O., Johansson J. Lipid bilayer polypeptide interactions studied by molecular dynamics simulation. Eur Biophys J. 1987;14(4):203–209. doi: 10.1007/BF00256353. [DOI] [PubMed] [Google Scholar]
- Eisinger J., Flores J., Petersen W. P. A milling crowd model for local and long-range obstructed lateral diffusion. Mobility of excimeric probes in the membrane of intact erythrocytes. Biophys J. 1986 May;49(5):987–1001. doi: 10.1016/S0006-3495(86)83727-4. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Elson E. L., Reidler J. A. Analysis of cell surface interactions by measurements of lateral mobility. J Supramol Struct. 1979;12(4):481–489. doi: 10.1002/jss.400120408. [DOI] [PubMed] [Google Scholar]
- Golan D. E., Alecio M. R., Veatch W. R., Rando R. R. Lateral mobility of phospholipid and cholesterol in the human erythrocyte membrane: effects of protein-lipid interactions. Biochemistry. 1984 Jan 17;23(2):332–339. doi: 10.1021/bi00297a024. [DOI] [PubMed] [Google Scholar]
- Goodman S. R., Krebs K. E., Whitfield C. F., Riederer B. M., Zagon I. S. Spectrin and related molecules. CRC Crit Rev Biochem. 1988;23(2):171–234. doi: 10.3109/10409238809088319. [DOI] [PubMed] [Google Scholar]
- Jay D., Cantley L. Structural aspects of the red cell anion exchange protein. Annu Rev Biochem. 1986;55:511–538. doi: 10.1146/annurev.bi.55.070186.002455. [DOI] [PubMed] [Google Scholar]
- Koppel D. E. Association dynamics and lateral transport in biological membranes. J Supramol Struct Cell Biochem. 1981;17(1):61–67. doi: 10.1002/jsscb.380170107. [DOI] [PubMed] [Google Scholar]
- Koppel D. E., Sheetz M. P., Schindler M. Matrix control of protein diffusion in biological membranes. Proc Natl Acad Sci U S A. 1981 Jun;78(6):3576–3580. doi: 10.1073/pnas.78.6.3576. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Low P. S. Structure and function of the cytoplasmic domain of band 3: center of erythrocyte membrane-peripheral protein interactions. Biochim Biophys Acta. 1986 Sep 22;864(2):145–167. doi: 10.1016/0304-4157(86)90009-2. [DOI] [PubMed] [Google Scholar]
- Nigg E. A., Cherry R. J. Anchorage of a band 3 population at the erythrocyte cytoplasmic membrane surface: protein rotational diffusion measurements. Proc Natl Acad Sci U S A. 1980 Aug;77(8):4702–4706. doi: 10.1073/pnas.77.8.4702. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Saxton M. J. Lateral diffusion in an archipelago. The effect of mobile obstacles. Biophys J. 1987 Dec;52(6):989–997. doi: 10.1016/S0006-3495(87)83291-5. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Saxton M. J. The membrane skeleton of erythrocytes. A percolation model. Biophys J. 1990 Jun;57(6):1167–1177. doi: 10.1016/S0006-3495(90)82636-9. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Saxton M. J. The membrane skeleton of erythrocytes: models of its effect on lateral diffusion. Int J Biochem. 1990;22(8):801–809. doi: 10.1016/0020-711x(90)90283-9. [DOI] [PubMed] [Google Scholar]
- Saxton M. J. The spectrin network as a barrier to lateral diffusion in erythrocytes. A percolation analysis. Biophys J. 1989 Jan;55(1):21–28. doi: 10.1016/S0006-3495(89)82776-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sheetz M. P., Schindler M., Koppel D. E. Lateral mobility of integral membrane proteins is increased in spherocytic erythrocytes. Nature. 1980 Jun 12;285(5765):510–511. doi: 10.1038/285510a0. [DOI] [PubMed] [Google Scholar]
- Tsuji A., Kawasaki K., Ohnishi S., Merkle H., Kusumi A. Regulation of band 3 mobilities in erythrocyte ghost membranes by protein association and cytoskeletal meshwork. Biochemistry. 1988 Sep 20;27(19):7447–7452. doi: 10.1021/bi00419a041. [DOI] [PubMed] [Google Scholar]
- Tsuji A., Ohnishi S. Restriction of the lateral motion of band 3 in the erythrocyte membrane by the cytoskeletal network: dependence on spectrin association state. Biochemistry. 1986 Oct 7;25(20):6133–6139. doi: 10.1021/bi00368a045. [DOI] [PubMed] [Google Scholar]