Serial studies of numbers of circulating T and B lymphocytes in children with acute lymphoblastic leukaemia (original) (raw)

Abstract

Serial studies of numbers of circulating T and B lymphocytes at monthly intervals in children with acute lymphoblastic leukaemia showed a marked fall in the number of B cells, relatively greater than that of T cells, early in the course of maintenance chemotherapy and immediately after a course of cranial irradiation. The fall in the number of B cell is not a consequence of long-term chemotherapy, and is possibly related to a specific event such as cranial irradiation.

245

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Carlson D. E., Lubet R. A. Effects of sublethal gamma radiation on T and B cell activity in the antibody response of mice. Radiat Res. 1976 Jan;65(1):111–119. [PubMed] [Google Scholar]
  2. Holland J. F., Glidewell O. Oncologists' reply: survival expectancy in acute lymphocytic leukemia. N Engl J Med. 1972 Oct 12;287(15):769–777. doi: 10.1056/NEJM197210122871512. [DOI] [PubMed] [Google Scholar]
  3. Sen L., Borella L. Expression of cell surface markers on T and B lymphocytes after long-term chemotherapy of acute leukemia. Cell Immunol. 1973 Oct;9(1):84–95. doi: 10.1016/0008-8749(73)90170-6. [DOI] [PubMed] [Google Scholar]
  4. Winterleitner H., Palencia C., Knapp W., Eibl M., Krepler P. Immunologische Charakterisierung lymphoider Zellen bei akuter lymphatischer Leukämie im Remissionsstadium. Padiatr Padol. 1975;10(3):237–243. [PubMed] [Google Scholar]