vivek vardhan | Pondicherry university (original) (raw)
You can find my article "Gamma irradiation of medicinally important plants and the enhancement of secondary metabolite production" via; http://www.tandfonline.com/eprint/mTnu3MphqmPSTcKzDupV/full
Supervisors: Dr. Lata I Shukla
Address: Department of Biotechnology,
Pondicherry University,
kalapet, Pondicherry.
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Papers by vivek vardhan
Nano express, Apr 16, 2020
Eco-friendly bio-compatible silver nanoparticles (Ag NPs) were successfully synthesized using Zin... more Eco-friendly bio-compatible silver nanoparticles (Ag NPs) were successfully synthesized using Zingiber officinale extract in a simple green route at room temperature. The phytoconstituents present in Zingiber officinale (Z. officinale) extract act as reducing and stabilizing agents. The size and crystallinity of spherical Ag NPs were confirmed through transmission electron microscopy (TEM) and X-ray diffraction (XRD) studies. The formation of silver nanoparticles was also confirmed from the UV–vis and FTIR spectra. Luminescence properties of europium (Eu) and samarium (Sm) complexes in the presence of silver were studied. The intensity of luminescence from Eu and Sm complexes were found to get enhanced or quenched with their concentrations in Ag NPs. Interesting nonlinear optical properties exhibited by Ag NPs were observed in the Z-scan experiment suggesting that they can be used as optical limiters for the picosecond (ps) time scale green laser. Silver nanoparticles were tested against colon cancer (HCT116) cells in vitro by MTT assay and they exhibited smaller IC50 values with better inhibition efficiency. Ag NPs induced apoptosis through the activation of Reactive oxygen species (ROS) and Caspase-3 pathways. Antibacterial activity of Ag NPs was analysed against Acinetobacter baumannii (A. baumannii) and Staphylococcus aureus (S. aureus) and they were found to be efficient in inhibiting the bacteria. The results indicate that the biosynthesized eco-friendly nanoparticles having high stability can lead to many applications such as good luminescence enhancement, optical limiting characteristics, anticancerous and antibacterial properties in optics and biomedicine.
Biotechnological Approaches to Enhance Plant Secondary Metabolites, 2021
Nano Express, 2020
Eco-friendly bio-compatible silver nanoparticles (Ag NPs) were successfully synthesized using Zin... more Eco-friendly bio-compatible silver nanoparticles (Ag NPs) were successfully synthesized using Zingiber officinale extract in a simple green route at room temperature. The phytoconstituents present in Zingiber officinale (Z. officinale) extract act as reducing and stabilizing agents. The size and crystallinity of spherical Ag NPs were confirmed through transmission electron microscopy (TEM) and X-ray diffraction (XRD) studies. The formation of silver nanoparticles was also confirmed from the UV–vis and FTIR spectra. Luminescence properties of europium (Eu) and samarium (Sm) complexes in the presence of silver were studied. The intensity of luminescence from Eu and Sm complexes were found to get enhanced or quenched with their concentrations in Ag NPs. Interesting nonlinear optical properties exhibited by Ag NPs were observed in the Z-scan experiment suggesting that they can be used as optical limiters for the picosecond (ps) time scale green laser. Silver nanoparticles were tested ag...
Radiation and environmental biophysics, Jan 17, 2018
The present article focuses on the influence of gamma irradiation and post-irradiation storage co... more The present article focuses on the influence of gamma irradiation and post-irradiation storage conditions on FT-IR spectra of 1 mm thick polystyrene irradiated with 51, 77 and 129 kGy. The increase in amplitude corresponding to 3600, 3400 and 2100 cm stretching frequencies clearly showing the formation of O-H and C=O bonds (~ 25%). On prolonged storage (2160 h) in the dark, there is an increase in O-H group (~ 28%). The electron cloud facilitates the formation of hydroxyl group in irradiated polystyrene. The post-irradiation treatment with heat conversely showed a reduction of O-H, C-H and C=O (9-16%) groups due to radical-radical recombination at higher temperatures and light intensities. This investigation finds its applications in memory devices, optical sensors, radiation dosimetry and different space and radiation facilities.
International Journal of Radiation Biology, 2017
International Journal of Radiation Biology , 2017
The profitable production of some important plant-based secondary metabolites (ginsenosides, sapo... more The profitable production of some important plant-based secondary metabolites (ginsenosides, saponins, camptothecin, shikonins etc.) in vitro by gamma irradiation is a current area of interest. We reviewed different types of secondary metabolites, their mode of synthesis and effect of γ-radiation on their yield for different plants, organs and in vitro cultures (callus, suspension, hairy root). Special effort has been made to review the biochemical mechanisms underlying the increase in secondary metabolites. A comparison of yield improvement with biotic and abiotic stresses was made.
Nano express, Apr 16, 2020
Eco-friendly bio-compatible silver nanoparticles (Ag NPs) were successfully synthesized using Zin... more Eco-friendly bio-compatible silver nanoparticles (Ag NPs) were successfully synthesized using Zingiber officinale extract in a simple green route at room temperature. The phytoconstituents present in Zingiber officinale (Z. officinale) extract act as reducing and stabilizing agents. The size and crystallinity of spherical Ag NPs were confirmed through transmission electron microscopy (TEM) and X-ray diffraction (XRD) studies. The formation of silver nanoparticles was also confirmed from the UV–vis and FTIR spectra. Luminescence properties of europium (Eu) and samarium (Sm) complexes in the presence of silver were studied. The intensity of luminescence from Eu and Sm complexes were found to get enhanced or quenched with their concentrations in Ag NPs. Interesting nonlinear optical properties exhibited by Ag NPs were observed in the Z-scan experiment suggesting that they can be used as optical limiters for the picosecond (ps) time scale green laser. Silver nanoparticles were tested against colon cancer (HCT116) cells in vitro by MTT assay and they exhibited smaller IC50 values with better inhibition efficiency. Ag NPs induced apoptosis through the activation of Reactive oxygen species (ROS) and Caspase-3 pathways. Antibacterial activity of Ag NPs was analysed against Acinetobacter baumannii (A. baumannii) and Staphylococcus aureus (S. aureus) and they were found to be efficient in inhibiting the bacteria. The results indicate that the biosynthesized eco-friendly nanoparticles having high stability can lead to many applications such as good luminescence enhancement, optical limiting characteristics, anticancerous and antibacterial properties in optics and biomedicine.
Biotechnological Approaches to Enhance Plant Secondary Metabolites, 2021
Nano Express, 2020
Eco-friendly bio-compatible silver nanoparticles (Ag NPs) were successfully synthesized using Zin... more Eco-friendly bio-compatible silver nanoparticles (Ag NPs) were successfully synthesized using Zingiber officinale extract in a simple green route at room temperature. The phytoconstituents present in Zingiber officinale (Z. officinale) extract act as reducing and stabilizing agents. The size and crystallinity of spherical Ag NPs were confirmed through transmission electron microscopy (TEM) and X-ray diffraction (XRD) studies. The formation of silver nanoparticles was also confirmed from the UV–vis and FTIR spectra. Luminescence properties of europium (Eu) and samarium (Sm) complexes in the presence of silver were studied. The intensity of luminescence from Eu and Sm complexes were found to get enhanced or quenched with their concentrations in Ag NPs. Interesting nonlinear optical properties exhibited by Ag NPs were observed in the Z-scan experiment suggesting that they can be used as optical limiters for the picosecond (ps) time scale green laser. Silver nanoparticles were tested ag...
Radiation and environmental biophysics, Jan 17, 2018
The present article focuses on the influence of gamma irradiation and post-irradiation storage co... more The present article focuses on the influence of gamma irradiation and post-irradiation storage conditions on FT-IR spectra of 1 mm thick polystyrene irradiated with 51, 77 and 129 kGy. The increase in amplitude corresponding to 3600, 3400 and 2100 cm stretching frequencies clearly showing the formation of O-H and C=O bonds (~ 25%). On prolonged storage (2160 h) in the dark, there is an increase in O-H group (~ 28%). The electron cloud facilitates the formation of hydroxyl group in irradiated polystyrene. The post-irradiation treatment with heat conversely showed a reduction of O-H, C-H and C=O (9-16%) groups due to radical-radical recombination at higher temperatures and light intensities. This investigation finds its applications in memory devices, optical sensors, radiation dosimetry and different space and radiation facilities.
International Journal of Radiation Biology, 2017
International Journal of Radiation Biology , 2017
The profitable production of some important plant-based secondary metabolites (ginsenosides, sapo... more The profitable production of some important plant-based secondary metabolites (ginsenosides, saponins, camptothecin, shikonins etc.) in vitro by gamma irradiation is a current area of interest. We reviewed different types of secondary metabolites, their mode of synthesis and effect of γ-radiation on their yield for different plants, organs and in vitro cultures (callus, suspension, hairy root). Special effort has been made to review the biochemical mechanisms underlying the increase in secondary metabolites. A comparison of yield improvement with biotic and abiotic stresses was made.