Medha Pathak • UCI Profiles (original) (raw)
- Visualizing PIEZO1 localization and activity in hiPSC-derived single cells and organoids with HaloTag technology. Nat Commun. 2025 Jul 01; 16(1):5556. Bertaccini GA, Casanellas I, Evans EL, Nourse JL, Dickinson GD, Liu G, Seal S, Ly AT, Holt JR, Wijerathne TD, Yan S, Hui EE, Lacroix JJ, Panicker MM, Upadhyayula S, Parker I, Pathak MM. PMID: 40593468; PMCID: PMC12217361.
View in: PubMed Mentions: 2 Fields:
Translation:HumansCells - A Multimodal Adaptive Optical Microscope For In Vivo Imaging from Molecules to Organisms. bioRxiv. 2025 Jun 03. Fu TM, Liu G, Milkie DE, Ruan X, Görlitz F, Shi Y, Ferro V, Divekar NS, Wang W, York HM, Kilic V, Mueller M, Liang Y, Daugird TA, Gacha-Garay MJ, Larkin KA, Adikes RC, Harrison N, Shirazinejad C, Williams S, Nourse JL, Sheu SH, Gao L, Li T, Mondal C, Achour K, Hercule W, Stabley D, Emmerich K, Dong P, Drubin D, Liu ZJ, Clapham D, Mumm JS, Koyama M, Killilea A, Bravo-Cordero JJ, Keene CD, Luo L, Kirchhausen T, Pathak MM, Arumugam S, Nunez JK, Gao R, Matus DQ, Martin BL, Swinburne IA, Betzig E, Legant WR, Upadhyayula S. PMID: 40661351; PMCID: PMC12259214.
View in: PubMed Mentions: - Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology. bioRxiv. 2025 Jan 25. Bertaccini GA, Casanellas I, Evans EL, Nourse JL, Dickinson GD, Liu G, Seal S, Ly AT, Holt JR, Wijerathne TD, Yan S, Hui EE, Lacroix JJ, Panicker MM, Upadhyayula S, Parker I, Pathak MM. PMID: 38187535; PMCID: PMC10769387.
View in: PubMed Mentions: - Single-particle tracking reveals heterogeneous PIEZO1 diffusion. Biophys J. 2025 Dec 16; 124(24):4457-4470. Ly AT, Freites JA, Bertaccini GA, Evans EL, Dickinson GD, Tobias DJ, Pathak MM. PMID: 39844465; PMCID: PMC12820997.
View in: PubMed Mentions: 2 Fields:
Translation:HumansCells - Piezo1-mediated mechanotransduction enhances macrophage oxidized low-density lipoprotein uptake and atherogenesis. PNAS Nexus. 2024 Nov; 3(11):pgae436. Atcha H, Kulkarni D, Meli VS, Veerasubramanian PK, Wang Y, Cahalan MD, Pathak MM, Liu WF. PMID: 39544498; PMCID: PMC11563038.
View in: PubMed Mentions: 3 - Piezo1-mediated mechanotransduction enhances macrophage oxLDL uptake and atherogenesis. 2024; pgae436. Hamza Atcha, Daanish Kulkarni, Vijaykumar S Meli, Praveen Krishna Veerasubramanian, Yuchun Wang, Michael D Cahalan, Medha M Pathak, Wendy F Liu. View Publication.
- Single-particle tracking reveals heterogeneous PIEZO1 diffusion. 2024. Alan T. Ly, J. Alfredo Freites, Gabriella A. Bertaccini, Elizabeth L. Evans, George D. Dickinson, Douglas J. Tobias, Medha M. Pathak. . View Publication.
- PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration. PLoS Comput Biol. 2024 Apr; 20(4):e1011855. Chen J, Holt JR, Evans EL, Lowengrub JS, Pathak MM. PMID: 38578817; PMCID: PMC11023636.
View in: PubMed Mentions: 5 Fields: - Author Correction: Membrane curvature governs the distribution of Piezo1 in live cells. Nat Commun. 2023 Jan 31; 14(1):524. Yang S, Miao X, Arnold S, Li B, Ly AT, Wang H, Wang M, Guo X, Pathak MM, Zhao W, Cox CD, Shi Z. PMID: 36720871; PMCID: PMC9889709.
View in: PubMed Mentions: Fields: - Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development. J Gen Physiol. 2022 10 03; 154(10). Nourse JL, Leung VM, Abuwarda H, Evans EL, Izquierdo-Ortiz E, Ly AT, Truong N, Smith S, Bhavsar H, Bertaccini G, Monuki ES, Panicker MM, Pathak MM. PMID: 36069933; PMCID: PMC9458470.
View in: PubMed Mentions: 22 Fields:
Translation:AnimalsCells - Correction: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing. Elife. 2022 Apr 01; 11. Holt JR, Zeng WZ, Evans EL, Woo SH, Ma S, Abuwarda H, Loud M, Patapoutian A, Pathak MM. PMID: 35362412; PMCID: PMC8975547.
View in: PubMed Mentions: 2 Fields: - Crosstalk Between CD11b and Piezo1 Mediates Macrophage Responses to Mechanical Cues. Front Immunol. 2021; 12:689397. Atcha H, Meli VS, Davis CT, Brumm KT, Anis S, Chin J, Jiang K, Pathak MM, Liu WF. PMID: 34630381; PMCID: PMC8493066.
View in: PubMed Mentions: 39 Fields:
Translation:AnimalsCells - Ion channel mediated mechanotransduction in immune cells. Curr Opin Solid State Mater Sci. 2021 Dec; 25(6). Hamza A, Amit J, Elizabeth L E, Medha M P, Michael D C, Wendy F L. PMID: 35645593; PMCID: PMC9131931.
View in: PubMed Mentions: 16 - Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses. Sci Adv. 2021 07; 7(28). Jairaman A, Othy S, Dynes JL, Yeromin AV, Zavala A, Greenberg ML, Nourse JL, Holt JR, Cahalan SM, Marangoni F, Parker I, Pathak MM, Cahalan MD. PMID: 34233878; PMCID: PMC8262815.
View in: PubMed Mentions: 57 Fields:
Translation:AnimalsCells - Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing. Nat Commun. 2021 05 31; 12(1):3256. Atcha H, Jairaman A, Holt JR, Meli VS, Nagalla RR, Veerasubramanian PK, Brumm KT, Lim HE, Othy S, Cahalan MD, Pathak MM, Liu WF. PMID: 34059671; PMCID: PMC8167181.
View in: PubMed Mentions: 256 Fields:
Translation:HumansAnimalsCells - Mechanobiology of neural development. Curr Opin Cell Biol. 2020 10; 66:104-111. Abuwarda H, Pathak MM. PMID: 32687993; PMCID: PMC7578076.
View in: PubMed Mentions: 23 Fields:
Translation:HumansAnimalsCells - Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers. Commun Biol. 2019; 2:298. Ellefsen KL, Holt JR, Chang AC, Nourse JL, Arulmoli J, Mekhdjian AH, Abuwarda H, Tombola F, Flanagan LA, Dunn AR, Parker I, Pathak MM. PMID: 31396578; PMCID: PMC6685976.
View in: PubMed Mentions: 121 Translation:HumansAnimalsCells - Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance. Front Endocrinol (Lausanne). 2019; 10:373. Zhao C, Sun Q, Tang L, Cao Y, Nourse JL, Pathak MM, Lu X, Yang Q. PMID: 31263454; PMCID: PMC6584899.
View in: PubMed Mentions: 27 Fields: - How cells channel their stress: Interplay between Piezo1 and the cytoskeleton. Semin Cell Dev Biol. 2017 11; 71:3-12. Nourse JL, Pathak MM. PMID: 28676421; PMCID: PMC6070642.
View in: PubMed Mentions: 120 Fields:
Translation:HumansAnimalsCells - The Hv1 proton channel responds to mechanical stimuli. J Gen Physiol. 2016 11; 148(5):405-418. Pathak MM, Tran T, Hong L, Joós B, Morris CE, Tombola F. PMID: 27799320; PMCID: PMC5089936.
View in: PubMed Mentions: 22 Fields:
Translation:HumansAnimalsCells - Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering. Acta Biomater. 2016 10 01; 43:122-138. Arulmoli J, Wright HJ, Phan DTT, Sheth U, Que RA, Botten GA, Keating M, Botvinick EL, Pathak MM, Zarembinski TI, Yanni DS, Razorenova OV, Hughes CCW, Flanagan LA. PMID: 27475528; PMCID: PMC5386322.
View in: PubMed Mentions: 56 Fields:
Translation:HumansAnimalsCells - Reflectin as a Material for Neural Stem Cell Growth. ACS Appl Mater Interfaces. 2016 Jan 13; 8(1):278-84. Phan L, Kautz R, Arulmoli J, Kim IH, Le DT, Shenk MA, Pathak MM, Flanagan LA, Tombola F, Gorodetsky AA. PMID: 26703760; PMCID: PMC4721522.
View in: PubMed Mentions: 8 Fields:
Translation:HumansAnimalsCells - Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner. Sci Rep. 2015 Feb 17; 5:8499. Arulmoli J, Pathak MM, McDonnell LP, Nourse JL, Tombola F, Earthman JC, Flanagan LA. PMID: 25686615; PMCID: PMC4330529.
View in: PubMed Mentions: 48 Fields:
Translation:AnimalsCells - Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):16148-53. Pathak MM, Nourse JL, Tran T, Hwe J, Arulmoli J, Le DT, Bernardis E, Flanagan LA, Tombola F. PMID: 25349416; PMCID: PMC4234578.
View in: PubMed Mentions: 340 Fields:
Translation:HumansCellsCTClinical Trials - Evidence for functional diversity between the voltage-gated proton channel Hv1 and its closest related protein HVRP1. PLoS One. 2014; 9(8):e105926. Kim IH, Hevezi P, Varga C, Pathak MM, Hong L, Ta D, Tran CT, Zlotnik A, Soltesz I, Tombola F. PMID: 25165868; PMCID: PMC4148356.
View in: PubMed Mentions: 12 Fields:
Translation:HumansAnimalsCells - Membrane biophysics define neuron and astrocyte progenitors in the neural lineage. Stem Cells. 2014 Mar; 32(3):706-16. Nourse JL, Prieto JL, Dickson AR, Lu J, Pathak MM, Tombola F, Demetriou M, Lee AP, Flanagan LA. PMID: 24105912; PMCID: PMC5367858.
View in: PubMed Mentions: 17 Fields:
Translation:AnimalsCells - Voltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domains. Neuron. 2013 Jan 23; 77(2):274-87. Hong L, Pathak MM, Kim IH, Ta D, Tombola F. PMID: 23352164; PMCID: PMC3559007.
View in: PubMed Mentions: 61 Fields:
Translation:HumansAnimalsCells - Closing in on the resting state of the Shaker K(+) channel. Neuron. 2007 Oct 04; 56(1):124-40. Pathak MM, Yarov-Yarovoy V, Agarwal G, Roux B, Barth P, Kohout S, Tombola F, Isacoff EY. PMID: 17920020.
View in: PubMed Mentions: 194 Fields:
Translation:AnimalsCells - The twisted ion-permeation pathway of a resting voltage-sensing domain. Nature. 2007 Feb 01; 445(7127):546-9. Tombola F, Pathak MM, Gorostiza P, Isacoff EY. PMID: 17187057.
View in: PubMed Mentions: 90 Fields:
Translation:AnimalsCells - How does voltage open an ion channel? Annu Rev Cell Dev Biol. 2006; 22:23-52. Tombola F, Pathak MM, Isacoff EY. PMID: 16704338.
View in: PubMed Mentions: 155 Fields:
Translation:AnimalsCells - How far will you go to sense voltage? Neuron. 2005 Dec 08; 48(5):719-25. Tombola F, Pathak MM, Isacoff EY. PMID: 16337910.
View in: PubMed Mentions: 37 Fields:
Translation:AnimalsCells - Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores. Neuron. 2005 Feb 03; 45(3):379-88. Tombola F, Pathak MM, Isacoff EY. PMID: 15694325.
View in: PubMed Mentions: 165 Fields:
Translation:AnimalsCells - The cooperative voltage sensor motion that gates a potassium channel. J Gen Physiol. 2005 Jan; 125(1):57-69. Pathak M, Kurtz L, Tombola F, Isacoff E. PMID: 15623895; PMCID: PMC1414780.
View in: PubMed Mentions: 80 Fields:
Translation:AnimalsCells
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
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