Bilal Ersen Kerman • USC Profiles (original) (raw)

  1. A perspective: PLA2G4A as drug target for vascular inflammation in Alzheimer's disease. Alzheimers Dement. 2026 Apr; 22(4):e71320. Kanwal A, Kerman BE, Wang S, Camey K, Li B, Flores-Aguilar L, Ali N, McIntire LB, Shu CA, Louie SG, Head E, Arvanitakis Z, Yassine HN. PMID: 41950067; PMCID: PMC13060764.
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  2. Evidence for cPLA2 activation in Alzheimer's disease synaptic pathology. Acta Neuropathol Commun. 2026 Feb 12; 14(1). Ma QL, Ebright B, Li B, Li J, Galvan J, Sanchez A, Renteln M, Dikeman D, Wang S, Kerman BE, Wang X, Manvelian M, Yu X, Seidler P, Gutierrez-Grebenkova B, Hjelm BE, Hawes D, Hiniker AE, Hurth KM, Bennett DA, Louie SG, Chui HC, Limon A, Arvanitakis Z, Yassine HN. PMID: 41680938.
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  3. Development of potent, selective cPLA2 inhibitors for targeting neuroinflammation in Alzheimer's disease and other neurodegenerative disorders. NPJ Drug Discov. 2026; 3(1):2. Sadybekov AV, Duro MV, Wang S, Ebright B, Dikeman D, Hugo C, Kerman BE, Ma QL, Nazarova AL, Sadybekov AA, Asante I, Louie SG, Katritch V, Yassine HN. PMID: 41523267; PMCID: PMC12779542.
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  4. Microglial States Are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer's Disease. Aging Cell. 2025 Oct; 24(10):e70189. Li B, Wang S, Kerman B, Hugo C, Shwab EK, Shu C, Chiba-Falek O, Arvanitakis Z, N Yassine H. PMID: 40790613; PMCID: PMC12507412.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansCells
  5. Increased cerebrospinal fluid and plasma apoE glycosylation is associated with reduced levels of Alzheimer's disease biomarkers. Alzheimers Res Ther. 2025 Jul 10; 17(1):151. Nedelkov D, Tsokolas ZE, Rodrigues MS, Sible I, Han SD, Kerman BE, Renteln M, Mack WJ, Pascoal TA, Yassine HN, Alzheimer’s Disease Neuroimaging Initiative. PMID: 40635030; PMCID: PMC12243426.
    View in: PubMed Mentions: 2 Fields:
    Translation:HumansCells
  6. Evidence for cPLA2 activation in Alzheimer's Disease Synaptic Pathology. bioRxiv. 2025 Apr 01. Ma QL, Ebright B, Li B, Li J, Galvan J, Sanchez A, Renteln M, Dikeman D, Wang S, Kerman BE, Seidler P, Gutierrez-Grebenkova B, Hjelm BE, Hawes D, Hiniker AE, Hurth KM, Bennett DA, Louie SG, Chui HC, Limon A, Arvanitakis Z, Yassine HN. PMID: 40236242; PMCID: PMC11996316.
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  7. Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD. Mol Neurodegener. 2025 Feb 04; 20(1):15. Wang S, Li B, Li J, Cai Z, Hugo C, Sun Y, Qian L, Tcw J, Chui HC, Dikeman D, Asante I, Louie SG, Bennett DA, Arvanitakis Z, Remaley AT, Kerman BE, Yassine HN. PMID: 39901180; PMCID: PMC11792374.
    View in: PubMed Mentions: 5 Fields:
    Translation:HumansAnimalsCells
  8. Increased cerebrospinal fluid and plasma apoE glycosylation is associated with reduced levels of Alzheimer's disease biomarkers. bioRxiv. 2024 Dec 21. Nedelkov D, Tsokolas ZE, Rodrigues MS, Sible I, Han SD, Kerman BE, Renteln M, Mack WJ, Pascoal TA, Yassine HN, Alzheimer’s Disease Neuroimaging Initiative. PMID: 39763949; PMCID: PMC11702616.
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  9. Microglia States are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer's Disease. bioRxiv. 2024 Nov 18. Li B, Wang S, Kerman B, Hugo C, Shwab EK, Shu C, Chiba-Falek O, Arvanitakis Z, Yassine H. PMID: 39605544; PMCID: PMC11601396.
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  10. Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD. Res Sq. 2024 May 14. Wang S, Li B, Cai Z, Hugo C, Li J, Sun Y, Qian L, Remaley AT, Tcw J, Chui HC, Bennett DA, Arvanitakis Z, Kerman B, Yassine H. PMID: 38798644; PMCID: PMC11118681.
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  11. Can the gut microbiome inform the effects of omega-3 fatty acid supplementation trials on cognition? Curr Opin Clin Nutr Metab Care. 2024 03 01; 27(2):116-124. Kerman BE, Self W, Yassine HN. PMID: 38170690; PMCID: PMC10872319.
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    Translation:HumansAnimals
  12. Synthesis and Preclinical Evaluation of 22-[18F]Fluorodocosahexaenoic Acid as a Positron Emission Tomography Probe for Monitoring Brain Docosahexaenoic Acid Uptake Kinetics. ACS Chem Neurosci. 2023 12 20; 14(24):4409-4418. Duro MVV, Van Valkenburgh J, Ingles DE, Tran J, Cai Z, Ebright B, Wang S, Kerman BE, Galvan J, Hwang SH, Sta Maria NS, Zanderigo F, Croteau E, Cunnane SC, Rapoport SI, Louie SG, Jacobs RE, Yassine HN, Chen K. PMID: 38048230; PMCID: PMC10739598.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansAnimals
  13. A multi-spectral myelin annotation tool for machine learning based myelin quantification. F1000Res. 2020; 9:1492. Çapar A, Çimen S, Aladag Z, Ekinci DA, Ayten UE, Kerman BE, Töreyin BU. PMID: 37990695; PMCID: PMC10660289.
    View in: PubMed Mentions: 1 Fields:
    Translation:Cells
  14. Identification of protein-protein interaction bridges for multiple sclerosis. Bioinformatics. 2023 04 03; 39(4). Yazici G, Kurt Vatandaslar B, Aydin Canturk I, Aydinli FI, Arici Duz O, Karakoc E, Kerman BE, Alkan C. PMID: 37018152; PMCID: PMC10115466.
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    Translation:HumansCells
  15. Associations of ApoE4 status and DHA supplementation on plasma and CSF lipid profiles and entorhinal cortex thickness. J Lipid Res. 2023 06; 64(6):100354. Bantugan MA, Xian H, Solomon V, Lee M, Cai Z, Wang S, Duro MV, Kerman BE, Fonteh A, Meuret C, Li M, Braskie MN, McIntire LBJ, Jurin L, Oberlin S, Evans J, Davis R, Mack WJ, Abdullah L, Yassine HN. PMID: 36958720; PMCID: PMC10230261.
    View in: PubMed Mentions: 4 Fields:
    Translation:Animals
  16. Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias. Alzheimers Dement. 2023 03; 19(3):1041-1066. Yassine HN, Self W, Kerman BE, Santoni G, Navalpur Shanmugam N, Abdullah L, Golden LR, Fonteh AN, Harrington MG, Gräff J, Gibson GE, Kalaria R, Luchsinger JA, Feldman HH, Swerdlow RH, Johnson LA, Albensi BC, Zlokovic BV, Tanzi R, Cunnane S, Samieri C, Scarmeas N, Bowman GL. PMID: 36479795; PMCID: PMC10576546.
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    Translation:HumansAnimals
  17. Radiosynthesis of 20-[18F]fluoroarachidonic acid for PET-MR imaging: Biological evaluation in ApoE4-TR mice. Prostaglandins Leukot Essent Fatty Acids. 2022 11; 186:102510. Van Valkenburgh J, Duro MVV, Burnham E, Chen Q, Wang S, Tran J, Kerman BE, Hwang SH, Liu X, Sta Maria NS, Zanderigo F, Croteau E, Rapoport SI, Cunnane SC, Jacobs RE, Yassine HN, Chen K. PMID: 36341886; PMCID: PMC9888757.
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    Translation:HumansAnimalsCells
  18. Two phases of macrophages: Inducing maturation and death of oligodendrocytes in vitro co-culture. J Neurosci Methods. 2022 12 01; 382:109723. Aydinli FI, Er S, Kerman BE. PMID: 36207003.
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    Translation:HumansCells
  19. Effect of the ABCA1 agonist CS-6253 on amyloid-β and lipoprotein metabolism in cynomolgus monkeys. Alzheimers Res Ther. 2022 06 24; 14(1):87. Noveir SD, Kerman BE, Xian H, Meuret C, Smadi S, Martinez AE, Johansson J, Zetterberg H, Parks BA, Kuklenyik Z, Mack WJ, Johansson JO, Yassine HN. PMID: 35751102; PMCID: PMC9229758.
    View in: PubMed Mentions: 9 Fields:
    Translation:HumansAnimals
  20. Multiple Sclerosis Biomarker Candidates Revealed by Cell-Type-Specific Interactome Analysis. OMICS. 2022 05; 26(5):305-317. Yurduseven K, Babal YK, Celik E, Kerman BE, Kurnaz IA. PMID: 35483054.
    View in: PubMed Mentions: 2 Fields:
    Translation:Humans
  21. Myelin detection in fluorescence microscopy images using machine learning. J Neurosci Methods. 2020 12 01; 346:108946. Çimen Yetis S, Çapar A, Ekinci DA, Ayten UE, Kerman BE, Töreyin BU. PMID: 32931810.
    View in: PubMed Mentions: 2 Fields:
    Translation:AnimalsCells
  22. Motoneuron expression profiling identifies an association between an axonal splice variant of HDGF-related protein 3 and peripheral myelination. J Biol Chem. 2020 08 21; 295(34):12233-12246. Kerman BE, Genoud S, Kurt Vatandaslar B, Denli AM, Georges Ghosh S, Xu X, Yeo GW, Aimone JB, Gage FH. PMID: 32647008; PMCID: PMC7443494.
    View in: PubMed Mentions: 1 Fields:
    Translation:AnimalsCells
  23. NextGen Voices: Science-inspired sustainable behavior. Science. 2019 05 31; 364(6443):822-824. Kumar B, Jensen MM, Strielkowski W, Johnston JT, Sharma V, Dandara C, Shehata MM, Struett MM, Nikolaou A, Szymanski DW, Abdul-Ghani R, Cao B, Varzinczak LH, Kerman BE, Arthur PK, Oda FS, Bohon W, Ellwanger JH, Tyner S, Jordan EJ, Murphy C. PMID: 31147504.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  24. Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. Elife. 2019 02 07; 8. Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, Fredlender C, Randolph-Moore L, Kshirsagar R, Xenitopoulos R, Chou G, Hah N, Muotri AR, Padmanabhan K, Semendeferi K, Gage FH. PMID: 30730291; PMCID: PMC6366899.
    View in: PubMed Mentions: 66 Fields:
    Translation:HumansAnimalsCells
  25. NextGen Voices: Quality mentoring. Science. 2018 10 05; 362(6410):22-24. Segal L, Agarwal D, Isaacson KJ, Oehmke TB, Kumar B, Chen JS, Cusimano JM, Negi S, Tiper I, Bakermans AJ, Jensen MM, Sanganyado E, Zaidi SS, Romero-Molina C, Martínez SE, Anderson SM, Santos GM, De Lella Ezcurra AL, Farragher J, Sharma V, Duncan G, Dutton-Regester K, Kim SA, Yu S, Schwendimann BA, Reichardt JKV, Halder A, Dennis AF, Ellwanger JH, Chiu YH, Kerman BE. PMID: 30287645.
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  26. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 06 06; 8(6):1757-1769. Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, Erikson G, Shokhirev M, Randolph-Moore L, Fredlender C, Dave S, Oefner R, Fitzpatrick C, Pena M, Barron JJ, Ku M, Denli AM, Kerman BE, Charnay P, Kelsoe JR, Marchetto MC, Gage FH. PMID: 28591655; PMCID: PMC5470172.
    View in: PubMed Mentions: 82 Fields:
    Translation:HumansCells
  27. Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice. Redox Biol. 2017 08; 12:657-665. Kilic U, Caglayan AB, Beker MC, Gunal MY, Caglayan B, Yalcin E, Kelestemur T, Gundogdu RZ, Yulug B, Yilmaz B, Kerman BE, Kilic E. PMID: 28395173; PMCID: PMC5388917.
    View in: PubMed Mentions: 65 Fields:
    Translation:AnimalsCells
  28. α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy. Acta Neuropathol. 2016 07; 132(1):59-75. Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J. PMID: 27059609; PMCID: PMC4912450.
    View in: PubMed Mentions: 46 Fields:
    Translation:AnimalsCells
  29. Primate-specific ORF0 contributes to retrotransposon-mediated diversity. Cell. 2015 Oct 22; 163(3):583-93. Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. PMID: 26496605.
    View in: PubMed Mentions: 132 Fields:
    Translation:HumansAnimalsCells
  30. In vitro myelin formation using embryonic stem cells. Development. 2015 Jun 15; 142(12):2213-25. Kerman BE, Kim HJ, Padmanabhan K, Mei A, Georges S, Joens MS, Fitzpatrick JA, Jappelli R, Chandross KJ, August P, Gage FH. PMID: 26015546; PMCID: PMC4483765.
    View in: PubMed Mentions: 46 Fields:
    Translation:AnimalsCells
  31. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nat Neurosci. 2014 Apr; 17(4):513-21. Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. PMID: 24584051; PMCID: PMC4113004.
    View in: PubMed Mentions: 179 Fields:
    Translation:HumansAnimalsCells
  32. A regenerative approach to the treatment of multiple sclerosis. Nature. 2013 Oct 17; 502(7471):327-332. Deshmukh VA, Tardif V, Lyssiotis CA, Green CC, Kerman B, Kim HJ, Padmanabhan K, Swoboda JG, Ahmad I, Kondo T, Gage FH, Theofilopoulos AN, Lawson BR, Schultz PG, Lairson LL. PMID: 24107995; PMCID: PMC4431622.
    View in: PubMed Mentions: 270 Fields:
    Translation:AnimalsCells
  33. Deficiency screen identifies a novel role for beta 2 tubulin in salivary gland and myoblast migration in the Drosophila embryo. Dev Dyn. 2009 Apr; 238(4):853-63. Jattani R, Patel U, Kerman B, Myat MM. PMID: 19253394; PMCID: PMC3105526.
    View in: PubMed Mentions: 5 Fields:
    Translation:AnimalsCells
  34. Intraorbital air simulating an intraocular foreign body. Am J Ophthalmol. 1997 Jun; 123(6):835-7. Bhavsar AR, Fong DS, Kerman B, Yoshizumi MO. PMID: 9535630.
    View in: PubMed Mentions: 4 Fields:
    Translation:Humans

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