Christian Pike • USC Profiles (original) (raw)

  1. Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity in a sexually dimorphic manner. J Neuroinflammation. 2025 Sep 26; 22(1):214. Liu J, Zaidi A, Pike CJ. PMID: 41013506; PMCID: PMC12465214.
    View in: PubMed Mentions: Fields:
    Translation:AnimalsCells
  2. Protection against APOE4-associated phenotypes with the longevity-promoting intervention 17α-estradiol in middle-aged male mice. Commun Med (Lond). 2025 Jun 10; 5(1):222. McGill CJ, Christensen A, Qian W, Thorwald MA, Lugo JG, Namvari S, White OS, Finch CE, Benayoun BA, Pike CJ. PMID: 40494894; PMCID: PMC12152157.
    View in: PubMed Mentions: 2
  3. Iron-associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice. Alzheimers Dement. 2025 Jan; 21(1):e14541. Thorwald MA, Godoy-Lugo JA, Garcia G, Silva J, Kim M, Christensen A, Mack WJ, Head E, O'Day PA, Benayoun BA, Morgan TE, Pike CJ, Higuchi-Sanabria R, Forman HJ, Finch CE. PMID: 39876821; PMCID: PMC11775463.
    View in: PubMed Mentions: 13 Fields:
    Translation:HumansAnimalsCells
  4. Effects of obesogenic diet and 17β-estradiol in female mice with APOE 3/3, 3/4, and 4/4 genotypes. Front Aging Neurosci. 2024; 16:1415072. Christensen A, McGill CJ, Qian W, Pike CJ. PMID: 39347015; PMCID: PMC11427389.
    View in: PubMed Mentions: 2
  5. Apolipoprotein E polymorphisms and female fertility in a transgenic mouse model of Alzheimer's disease. Sci Rep. 2024 07 10; 14(1):15873. Medegan Fagla B, York J, Christensen A, Dela Rosa C, Balu D, Pike CJ, Tai LM, Buhimschi IA. PMID: 38982272; PMCID: PMC11233746.
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    Translation:HumansAnimals
  6. Iron associated lipid peroxidation in Alzheimers disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice. bioRxiv. 2024 Jun 13. Thorwald M, Godoy-Lugo JA, Garcia G, Silva J, Kim M, Christensen A, Mack WJ, Head E, O'Day PA, Benayoun BA, Morgan TE, Pike CJ, Higuchi-Sanabria R, Forman HJ, Finch CE. PMID: 37034750; PMCID: PMC10081222.
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  7. Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology. Aging Cell. 2024 07; 23(7):e14153. Miller B, Kim SJ, Cao K, Mehta HH, Thumaty N, Kumagai H, Iida T, McGill C, Pike CJ, Nurmakova K, Levine ZA, Sullivan PM, Yen K, Ertekin-Taner N, Atzmon G, Barzilai N, Cohen P. PMID: 38520065; PMCID: PMC11258485.
    View in: PubMed Mentions: 5 Fields:
    Translation:HumansAnimals
  8. Protection against APOE4 -associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice. bioRxiv. 2024 Mar 14. McGill CJ, Christensen A, Qian W, Thorwald MA, Lugo JG, Namvari S, White OS, Finch CE, Benayoun BA, Pike CJ. PMID: 38559059; PMCID: PMC10980056.
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  9. Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity. bioRxiv. 2024 Feb 14. Liu J, Zaidi A, Pike CJ. PMID: 38405877; PMCID: PMC10888944.
    View in: PubMed Mentions:
  10. Microglial TLR4 Mediates White Matter Injury in a Combined Model of Diesel Exhaust Exposure and Cerebral Hypoperfusion. Stroke. 2024 04; 55(4):1090-1093. Shkirkova K, Demetriou AN, Sizdahkhani S, Lamorie-Foote K, Zhang H, Morales M, Chen S, Zhao L, Diaz A, Godoy-Lugo JA, Zhou B, Zhang N, Li A, Mack WJ, Sioutas C, Thorwald MA, Finch CE, Pike C, Mack WJ. PMID: 38299349; PMCID: PMC10978264.
    View in: PubMed Mentions: 10 Fields:
    Translation:AnimalsCells
  11. Effects of APOE Genotype and Western Diet on Metabolic Phenotypes in Female Mice. Metabolites. 2023 Feb 16; 13(2). Christensen A, Pike CJ. PMID: 36837905; PMCID: PMC9959618.
    View in: PubMed Mentions: 1
  12. APOE genotype and biological sex regulate astroglial interactions with amyloid plaques in Alzheimer's disease mice. J Neuroinflammation. 2022 Dec 01; 19(1):286. Stephen TL, Breningstall B, Suresh S, McGill CJ, Pike CJ. PMID: 36457019; PMCID: PMC9714101.
    View in: PubMed Mentions: 7 Fields:
    Translation:AnimalsCells
  13. Role of estrogen in women's Alzheimer's disease risk as modified by APOE. J Neuroendocrinol. 2023 02; 35(2):e13209. Valencia-Olvera AC, Maldonado Weng J, Christensen A, LaDu MJ, Pike CJ. PMID: 36420620; PMCID: PMC10049970.
    View in: PubMed Mentions: 31 Fields:
    Translation:Humans
  14. Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models. Cell Rep. 2022 09 27; 40(13):111417. Rangan P, Lobo F, Parrella E, Rochette N, Morselli M, Stephen TL, Cremonini AL, Tagliafico L, Persia A, Caffa I, Monacelli F, Odetti P, Bonfiglio T, Nencioni A, Pigliautile M, Boccardi V, Mecocci P, Pike CJ, Cohen P, LaDu MJ, Pellegrini M, Xia K, Tran K, Ann B, Chowdhury D, Longo VD. PMID: 36170815; PMCID: PMC9648488.
    View in: PubMed Mentions: 26 Fields:
    Translation:Animals
  15. Androgens Regulate Tau Phosphorylation Through Phosphatidylinositol 3-Kinase-Protein Kinase B-Glycogen Synthase Kinase 3β Signaling. Neuroscience. 2025 Mar 05; 568:503-518. Yao M, Rosario ER, Soper JC, Pike CJ. PMID: 35777535; PMCID: PMC9797620.
    View in: PubMed Mentions: 9 Fields:
    Translation:AnimalsCells
  16. Microglial transcription profiles in mouse and human are driven by APOE4 and sex. iScience. 2021 Nov 19; 24(11):103238. Moser VA, Workman MJ, Hurwitz SJ, Lipman RM, Pike CJ, Svendsen CN. PMID: 34746703; PMCID: PMC8551075.
    View in: PubMed Mentions: 15
  17. Second to fourth digit ratio (2D:4D) is associated with dementia in women. Early Hum Dev. 2020 10; 149:105152. Jiang J, Young K, Pike CJ. PMID: 32781308; PMCID: PMC7484057.
    View in: PubMed Mentions: 6 Fields:
    Translation:Humans
  18. Dementia risk in women higher in same-sex than opposite-sex twins. Alzheimers Dement (Amst). 2020; 12(1):e12049. Luo J, Beam CR, Karlsson IK, Pike CJ, Reynolds CA, Gatz M. PMID: 32582836; PMCID: PMC7306516.
    View in: PubMed Mentions: 8
  19. Aging Reduces Estradiol Protection Against Neural but Not Metabolic Effects of Obesity in Female 3xTg-AD Mice. Front Aging Neurosci. 2020; 12:113. Christensen A, Liu J, Pike CJ. PMID: 32431604; PMCID: PMC7214793.
    View in: PubMed Mentions: 13
  20. Staining and Quantification of β-Amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease. Methods Mol Biol. 2020; 2144:211-221. Christensen A, Pike CJ. PMID: 32410038; PMCID: PMC7299244.
    View in: PubMed Mentions: 15 Fields:
    Translation:HumansAnimals
  21. APOE genotype and sex affect microglial interactions with plaques in Alzheimer's disease mice. Acta Neuropathol Commun. 2019 05 21; 7(1):82. Stephen TL, Cacciottolo M, Balu D, Morgan TE, LaDu MJ, Finch CE, Pike CJ. PMID: 31113487; PMCID: PMC6528326.
    View in: PubMed Mentions: 62 Fields:
    Translation:AnimalsCells
  22. APOE genotype affects metabolic and Alzheimer-related outcomes induced by Western diet in female EFAD mice. FASEB J. 2019 03; 33(3):4054-4066. Christensen A, Pike CJ. PMID: 30509127; PMCID: PMC6404574.
    View in: PubMed Mentions: 18 Fields:
    Translation:Animals
  23. TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity. J Neuroinflammation. 2018 Nov 05; 15(1):306. Moser VA, Uchoa MF, Pike CJ. PMID: 30396359; PMCID: PMC6217784.
    View in: PubMed Mentions: 27 Fields:
    Translation:AnimalsCells
  24. Effects of aging, high-fat diet, and testosterone treatment on neural and metabolic outcomes in male brown Norway rats. Neurobiol Aging. 2019 01; 73:145-160. Moser VA, Christensen A, Liu J, Zhou A, Yagi S, Beam CR, Galea L, Pike CJ. PMID: 30359877; PMCID: PMC6252085.
    View in: PubMed Mentions: 11 Fields:
    Translation:Animals
  25. Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans. Sci Rep. 2018 09 21; 8(1):14212. Yen K, Wan J, Mehta HH, Miller B, Christensen A, Levine ME, Salomon MP, Brandhorst S, Xiao J, Kim SJ, Navarrete G, Campo D, Harry GJ, Longo V, Pike CJ, Mack WJ, Hodis HN, Crimmins EM, Cohen P. PMID: 30242290; PMCID: PMC6154958.
    View in: PubMed Mentions: 59 Fields:
    Translation:HumansAnimalsCells
  26. TSPO ligand PK11195 improves Alzheimer-related outcomes in aged female 3xTg-AD mice. Neurosci Lett. 2018 09 14; 683:7-12. Christensen A, Pike CJ. PMID: 29925037; PMCID: PMC6436542.
    View in: PubMed Mentions: 21 Fields:
    Translation:Animals
  27. The Oxygen Paradox, the French Paradox, and age-related diseases. Geroscience. 2017 12; 39(5-6):499-550. Davies JMS, Cillard J, Friguet B, Cadenas E, Cadet J, Cayce R, Fishmann A, Liao D, Bulteau AL, Derbré F, Rébillard A, Burstein S, Hirsch E, Kloner RA, Jakowec M, Petzinger G, Sauce D, Sennlaub F, Limon I, Ursini F, Maiorino M, Economides C, Pike CJ, Cohen P, Salvayre AN, Halliday MR, Lundquist AJ, Jakowec NA, Mechta-Grigoriou F, Mericskay M, Mariani J, Li Z, Huang D, Grant E, Forman HJ, Finch CE, Sun PY, Pomatto LCD, Agbulut O, Warburton D, Neri C, Rouis M, Cillard P, Capeau J, Rosenbaum J, Davies KJA. PMID: 29270905; PMCID: PMC5745211.
    View in: PubMed Mentions: 37 Fields:
    Translation:Humans
  28. Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice. eNeuro. 2017 May-Jun; 4(3). Moser VA, Pike CJ. PMID: 28612048; PMCID: PMC5469027.
    View in: PubMed Mentions: 54 Fields:
    Translation:HumansAnimals
  29. Age-dependent regulation of obesity and Alzheimer-related outcomes by hormone therapy in female 3xTg-AD mice. PLoS One. 2017; 12(6):e0178490. Christensen A, Pike CJ. PMID: 28575011; PMCID: PMC5456100.
    View in: PubMed Mentions: 20 Fields:
    Translation:Animals
  30. Sex and the development of Alzheimer's disease. J Neurosci Res. 2017 01 02; 95(1-2):671-680. Pike CJ. PMID: 27870425; PMCID: PMC5120614.
    View in: PubMed Mentions: 209 Fields:
    Translation:HumansAnimals
  31. Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors. Front Neuroendocrinol. 2016 10; 43:60-82. Uchoa MF, Moser VA, Pike CJ. PMID: 27651175; PMCID: PMC5123957.
    View in: PubMed Mentions: 47 Fields:
    Translation:HumansAnimals
  32. Obesity and sex interact in the regulation of Alzheimer's disease. Neurosci Biobehav Rev. 2016 Aug; 67:102-18. Moser VA, Pike CJ. PMID: 26708713; PMCID: PMC4912955.
    View in: PubMed Mentions: 50 Fields:
    Translation:Humans
  33. The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice. Neurobiol Aging. 2016 Jan; 37:47-57. Cacciottolo M, Christensen A, Moser A, Liu J, Pike CJ, Smith C, LaDu MJ, Sullivan PM, Morgan TE, Dolzhenko E, Charidimou A, Wahlund LO, Wiberg MK, Shams S, Chiang GC, Alzheimer's Disease Neuroimaging Initiative, Finch CE. PMID: 26686669; PMCID: PMC4687024.
    View in: PubMed Mentions: 57 Fields:
    Translation:HumansAnimals
  34. Menopause, obesity and inflammation: interactive risk factors for Alzheimer's disease. Front Aging Neurosci. 2015; 7:130. Christensen A, Pike CJ. PMID: 26217222; PMCID: PMC4493396.
    View in: PubMed Mentions: 54
  35. The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. Neurobiol Aging. 2015 Jul; 36(7):2282-2295. Yin F, Yao J, Sancheti H, Feng T, Melcangi RC, Morgan TE, Finch CE, Pike CJ, Mack WJ, Cadenas E, Brinton RD. PMID: 25921624; PMCID: PMC4416218.
    View in: PubMed Mentions: 75 Fields:
    Translation:AnimalsCells
  36. Impact of continuous versus discontinuous progesterone on estradiol regulation of neuron viability and sprouting after entorhinal cortex lesion in female rats. Endocrinology. 2015 Mar; 156(3):1091-9. Barron AM, Brown MA, Morgan TE, Pike CJ. PMID: 25514084; PMCID: PMC4330320.
    View in: PubMed Mentions: 2 Fields:
    Translation:AnimalsCells
  37. Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function. J Neuroinflammation. 2014 Sep 16; 11:162. Jayaraman A, Lent-Schochet D, Pike CJ. PMID: 25224590; PMCID: PMC4190446.
    View in: PubMed Mentions: 44 Fields:
    Translation:AnimalsCells
  38. Alzheimer's disease and type 2 diabetes: multiple mechanisms contribute to interactions. Curr Diab Rep. 2014 Apr; 14(4):476. Jayaraman A, Pike CJ. PMID: 24526623; PMCID: PMC3985543.
    View in: PubMed Mentions: 96 Fields:
    Translation:HumansAnimals
  39. Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats. Endocrinology. 2014 Apr; 155(4):1398-406. Jayaraman A, Christensen A, Moser VA, Vest RS, Miller CP, Hattersley G, Pike CJ. PMID: 24428527; PMCID: PMC3959610.
    View in: PubMed Mentions: 8 Fields:
    Translation:AnimalsCells
  40. Differential effects of synthetic progestagens on neuron survival and estrogen neuroprotection in cultured neurons. Mol Cell Endocrinol. 2014 Mar 25; 384(1-2):52-60. Jayaraman A, Pike CJ. PMID: 24424444; PMCID: PMC3954450.
    View in: PubMed Mentions: 9 Fields:
    Translation:AnimalsCells
  41. Sex-specific effects of high fat diet on indices of metabolic syndrome in 3xTg-AD mice: implications for Alzheimer's disease. PLoS One. 2013; 8(10):e78554. Barron AM, Rosario ER, Elteriefi R, Pike CJ. PMID: 24205258; PMCID: PMC3810257.
    View in: PubMed Mentions: 68 Fields:
    Translation:AnimalsCells
  42. Ligand for translocator protein reverses pathology in a mouse model of Alzheimer's disease. J Neurosci. 2013 May 15; 33(20):8891-7. Barron AM, Garcia-Segura LM, Caruso D, Jayaraman A, Lee JW, Melcangi RC, Pike CJ. PMID: 23678130; PMCID: PMC3733563.
    View in: PubMed Mentions: 77 Fields:
    Translation:HumansAnimals
  43. Age-related changes in neuroactive steroid levels in 3xTg-AD mice. Neurobiol Aging. 2013 Apr; 34(4):1080-9. Caruso D, Barron AM, Brown MA, Abbiati F, Carrero P, Pike CJ, Garcia-Segura LM, Melcangi RC. PMID: 23122920; PMCID: PMC3545103.
    View in: PubMed Mentions: 58 Fields:
    Translation:Animals
  44. 17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. Endocrinology. 2012 Nov; 153(11):5467-79. Jayaraman A, Carroll JC, Morgan TE, Lin S, Zhao L, Arimoto JM, Murphy MP, Beckett TL, Finch CE, Brinton RD, Pike CJ. PMID: 22962256; PMCID: PMC3473201.
    View in: PubMed Mentions: 38 Fields:
    Translation:AnimalsCells
  45. Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD mice. Brain Res. 2012 Jul 23; 1466:137-45. Rosario ER, Carroll JC, Pike CJ. PMID: 22587890; PMCID: PMC3399667.
    View in: PubMed Mentions: 21 Fields:
    Translation:Animals
  46. Gender, sex steroid hormones, and Alzheimer's disease. Horm Behav. 2013 Feb; 63(2):301-7. Vest RS, Pike CJ. PMID: 22554955; PMCID: PMC3413783.
    View in: PubMed Mentions: 107 Fields:
    Translation:HumansAnimals
  47. Caspase activation contributes to astrogliosis. Brain Res. 2012 Apr 23; 1450:102-15. Aras R, Barron AM, Pike CJ. PMID: 22436850; PMCID: PMC3319728.
    View in: PubMed Mentions: 23 Fields:
    Translation:AnimalsCells
  48. Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles. PLoS One. 2012; 7(2):e31267. Zhao L, Morgan TE, Mao Z, Lin S, Cadenas E, Finch CE, Pike CJ, Mack WJ, Brinton RD. PMID: 22393359; PMCID: PMC3290616.
    View in: PubMed Mentions: 31 Fields:
    Translation:AnimalsCells
  49. Sex hormones, aging, and Alzheimer's disease. Front Biosci (Elite Ed). 2012 01 01; 4(3):976-97. Barron AM, Pike CJ. PMID: 22201929; PMCID: PMC3511049.
    View in: PubMed Mentions: 98 Fields:
    Translation:Humans
  50. Progesterone inhibits estrogen-mediated neuroprotection against excitotoxicity by down-regulating estrogen receptor-β. J Neurochem. 2010 Dec; 115(5):1277-87. Aguirre C, Jayaraman A, Pike C, Baudry M. PMID: 20977477; PMCID: PMC3010223.
    View in: PubMed Mentions: 37 Fields:
    Translation:AnimalsCells
  51. Sex differences in β-amyloid accumulation in 3xTg-AD mice: role of neonatal sex steroid hormone exposure. Brain Res. 2010 Dec 17; 1366:233-45. Carroll JC, Rosario ER, Kreimer S, Villamagna A, Gentzschein E, Stanczyk FZ, Pike CJ. PMID: 20934413; PMCID: PMC2993873.
    View in: PubMed Mentions: 158 Fields:
    Translation:HumansAnimals
  52. Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways. Brain Res. 2010 Nov 04; 1359:281-90. Rosario ER, Carroll J, Pike CJ. PMID: 20807511; PMCID: PMC2965035.
    View in: PubMed Mentions: 62 Fields:
    Translation:AnimalsCells
  53. Continuous and cyclic progesterone differentially interact with estradiol in the regulation of Alzheimer-like pathology in female 3xTransgenic-Alzheimer's disease mice. Endocrinology. 2010 Jun; 151(6):2713-22. Carroll JC, Rosario ER, Villamagna A, Pike CJ. PMID: 20410196; PMCID: PMC2875823.
    View in: PubMed Mentions: 51 Fields:
    Translation:AnimalsCells
  54. Age-related changes in serum and brain levels of androgens in male Brown Norway rats. Neuroreport. 2009 Nov 25; 20(17):1534-7. Rosario ER, Chang L, Beckett TL, Carroll JC, Paul Murphy M, Stanczyk FZ, Pike CJ. PMID: 19829160; PMCID: PMC6042843.
    View in: PubMed Mentions: 21 Fields:
    Translation:AnimalsCells
  55. Dihydrotestosterone activates CREB signaling in cultured hippocampal neurons. Brain Res. 2009 Nov 17; 1298:1-12. Nguyen TV, Yao M, Pike CJ. PMID: 19729001; PMCID: PMC2775803.
    View in: PubMed Mentions: 22 Fields:
    Translation:AnimalsCells
  56. Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease. Neurobiol Aging. 2011 Apr; 32(4):604-13. Rosario ER, Chang L, Head EH, Stanczyk FZ, Pike CJ. PMID: 19428144; PMCID: PMC2930132.
    View in: PubMed Mentions: 135 Fields:
    Translation:Humans
  57. Protective actions of sex steroid hormones in Alzheimer's disease. Front Neuroendocrinol. 2009 Jul; 30(2):239-58. Pike CJ, Carroll JC, Rosario ER, Barron AM. PMID: 19427328; PMCID: PMC2728624.
    View in: PubMed Mentions: 227 Fields:
    Translation:HumansAnimals
  58. Progesterone blocks estrogen neuroprotection from kainate in middle-aged female rats. Neurosci Lett. 2008 Nov 21; 445(3):229-32. Carroll JC, Rosario ER, Pike CJ. PMID: 18790007; PMCID: PMC2591925.
    View in: PubMed Mentions: 23 Fields:
    Translation:AnimalsCells
  59. Androgens regulate neprilysin expression: role in reducing beta-amyloid levels. J Neurochem. 2008 Jun 01; 105(6):2477-88. Yao M, Nguyen TV, Rosario ER, Ramsden M, Pike CJ. PMID: 18346198.
    View in: PubMed Mentions: 44 Fields:
    Translation:HumansAnimalsCells
  60. Progesterone receptors: form and function in brain. Front Neuroendocrinol. 2008 May; 29(2):313-39. Brinton RD, Thompson RF, Foy MR, Baudry M, Wang J, Finch CE, Morgan TE, Pike CJ, Mack WJ, Stanczyk FZ, Nilsen J. PMID: 18374402; PMCID: PMC2398769.
    View in: PubMed Mentions: 278 Fields:
    Translation:HumansAnimalsCells
  61. Selective estrogen receptor modulators differentially regulate Alzheimer-like changes in female 3xTg-AD mice. Endocrinology. 2008 May; 149(5):2607-11. Carroll JC, Pike CJ. PMID: 18276750; PMCID: PMC2329277.
    View in: PubMed Mentions: 58 Fields:
    Translation:Animals
  62. Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice. J Neurosci. 2007 Nov 28; 27(48):13357-65. Carroll JC, Rosario ER, Chang L, Stanczyk FZ, Oddo S, LaFerla FM, Pike CJ. PMID: 18045930; PMCID: PMC6673397.
    View in: PubMed Mentions: 192 Fields:
    Translation:Animals
  63. Androgen cell signaling pathways involved in neuroprotective actions. Horm Behav. 2008 May; 53(5):693-705. Pike CJ, Nguyen TV, Ramsden M, Yao M, Murphy MP, Rosario ER. PMID: 18222446; PMCID: PMC2424283.
    View in: PubMed Mentions: 72 Fields:
    Translation:HumansCells
  64. Androgen regulation of beta-amyloid protein and the risk of Alzheimer's disease. Brain Res Rev. 2008 Mar; 57(2):444-53. Rosario ER, Pike CJ. PMID: 17658612; PMCID: PMC2390933.
    View in: PubMed Mentions: 37 Fields:
    Translation:HumansAnimals
  65. Flutamide and cyproterone acetate exert agonist effects: induction of androgen receptor-dependent neuroprotection. Endocrinology. 2007 Jun; 148(6):2936-43. Nguyen TV, Yao M, Pike CJ. PMID: 17347309.
    View in: PubMed Mentions: 32 Fields:
    Translation:AnimalsCells
  66. Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death. J Neurosci. 2007 Feb 07; 27(6):1422-33. Yao M, Nguyen TV, Pike CJ. PMID: 17287517; PMCID: PMC6673600.
    View in: PubMed Mentions: 45 Fields:
    Translation:AnimalsCells
  67. Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer's disease. J Neurosci. 2006 Dec 20; 26(51):13384-9. Rosario ER, Carroll JC, Oddo S, LaFerla FM, Pike CJ. PMID: 17182789; PMCID: PMC6674990.
    View in: PubMed Mentions: 75 Fields:
    Translation:Animals
  68. Progestins inhibit the neuroprotective effects of estrogen in rat hippocampus. Brain Res. 2006 Jul 12; 1099(1):206-10. Rosario ER, Ramsden M, Pike CJ. PMID: 16793026.
    View in: PubMed Mentions: 39 Fields:
    Translation:Animals
  69. Androgens, aging, and Alzheimer's disease. Endocrine. 2006 Apr; 29(2):233-41. Pike CJ, Rosario ER, Nguyen TV. PMID: 16785599.
    View in: PubMed Mentions: 28 Fields:
    Translation:HumansAnimalsCells
  70. Conventional protein kinase C isoforms mediate neuroprotection induced by phorbol ester and estrogen. J Neurochem. 2006 Jan; 96(1):204-17. Cordey M, Pike CJ. PMID: 16336227.
    View in: PubMed Mentions: 11 Fields:
    Translation:AnimalsCells
  71. Androgens activate mitogen-activated protein kinase signaling: role in neuroprotection. J Neurochem. 2005 Sep; 94(6):1639-51. Nguyen TV, Yao M, Pike CJ. PMID: 16011741.
    View in: PubMed Mentions: 80 Fields:
    Translation:AnimalsCells
  72. The synthetic estrogen 4-estren-3 alpha,17 beta-diol (estren) induces estrogen-like neuroprotection. Neurobiol Dis. 2005 Jun-Jul; 19(1-2):331-9. Cordey M, Gundimeda U, Gopalakrishna R, Pike CJ. PMID: 15837589.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
  73. Neuroprotective properties of selective estrogen receptor agonists in cultured neurons. Brain Res. 2005 May 31; 1045(1-2):217-23. Cordey M, Pike CJ. PMID: 15910780.
    View in: PubMed Mentions: 21 Fields:
    Translation:AnimalsCells
  74. Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w. J Neurosci. 2005 Feb 02; 25(5):1149-58. Yao M, Nguyen TV, Pike CJ. PMID: 15689551; PMCID: PMC6725978.
    View in: PubMed Mentions: 83 Fields:
    Translation:HumansAnimalsCells
  75. Age-related testosterone depletion and the development of Alzheimer disease. JAMA. 2004 Sep 22; 292(12):1431-2. Rosario ER, Chang L, Stanczyk FZ, Pike CJ. PMID: 15383512.
    View in: PubMed Mentions: 83 Fields:
    Translation:Humans
  76. Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion. Brain Res. 2003 May 09; 971(2):239-44. Ramsden M, Berchtold NC, Patrick Kesslak J, Cotman CW, Pike CJ. PMID: 12706240.
    View in: PubMed Mentions: 17 Fields:
    Translation:AnimalsCells
  77. Estrogen activates protein kinase C in neurons: role in neuroprotection. J Neurochem. 2003 Mar; 84(6):1340-8. Cordey M, Gundimeda U, Gopalakrishna R, Pike CJ. PMID: 12614334.
    View in: PubMed Mentions: 38 Fields:
    Translation:AnimalsCells
  78. The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its conformation, aggregation, and neurotoxic properties. Neuromolecular Med. 2002; 1(1):81-94. Soreghan B, Pike C, Kayed R, Tian W, Milton S, Cotman C, Glabe CG. PMID: 12025818.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansCells
  79. Testosterone attenuates beta-amyloid toxicity in cultured hippocampal neurons. Brain Res. 2001 Nov 16; 919(1):160-5. Pike CJ. PMID: 11689174.
    View in: PubMed Mentions: 91 Fields:
    Translation:AnimalsCells

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