Etan Orgel • USC Profiles (original) (raw)

  1. Lipidomic profiles associated with treatment related hepatotoxicity in children with acute lymphoblastic leukemia. Support Care Cancer. 2026 Feb 17; 34(3):209. Mason EJ, Schraw JM, Woodhouse JP, Gramatges MM, Williams KJ, Chen B, Harrell MB, Taylor OA, Scheurer ME, Lupo PJ, Rabin KR, Yi JS, Huynh V, Mittelman SD, Orgel E, Brown A. PMID: 41699110; PMCID: PMC12909625.
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    Translation:Humans
  2. Incidence and outcomes of treatment-associated hepatotoxicity during pediatric acute lymphoblastic leukemia induction therapy: a Reducing Ethnic Disparities in Acute Leukemia (REDIAL) Consortium report. Haematologica. 2026 Jan 22. Chavana AN, Mason EJ, Woodhouse JP, Taylor OA, Gramatges MM, Yi JS, Pruitt S, Bernhardt BM, Ludwig K, Klesse L, Heym K, Griffin T, Roberts M, Erana R, Bernini JC, Zhu H, Lupo PJ, Rabin KR, Scheurer ME, Mittelman SD, Huynh V, Orgel E, Brown AL. PMID: 41568528.
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  3. An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy. Blood Adv. 2025 Nov 25; 9(22):5802-5810. Mason EJ, Crain AM, Scheurer ME, Lupo PJ, Rabin KR, Taylor OA, Roberts M, Woodhouse JP, Chavana A, Ludwig K, Klesse L, Heym K, Griffin T, Erana R, Bernini JC, Gramatges MM, Yi JS, Pruitt SL, Bernhardt MB, Zhu H, Mittelman SD, Huynh V, Orgel E, Schraw JM, Brown AL. PMID: 40829116; PMCID: PMC12663015.
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  4. Sedentary behavior in children, adolescents, and young adults treated for cancer: A scoping review of health outcomes and interventions. J Cancer Surviv. 2025 Nov 11. Ivory BJ, Moore K, Dinalo JE, Kadan-Lottick NS, Dieli-Conwright CM, Orgel E, Ness KK, Freyer DR, Belcher BR. PMID: 41217621.
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  5. Optimizing Asparaginase Treatment for Adolescent and Young Adult (AYA) Patients With Acute Lymphoblastic Leukemia: US Consensus Panel Recommendations. Am J Hematol. 2026 Jan; 101(1):41-55. Aldoss I, Ali A, Cassaday RD, Curran EK, Luskin MR, Maese LD, Orgel E, Douer D. PMID: 41074700; PMCID: PMC12669943.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  6. Rapid Diagnostic Stewardship and Blood Culture Use in a Pediatric Medical Center. JAMA Netw Open. 2025 Oct 01; 8(10):e2535580. Vaugon E, Costales C, Assad Z, Barter T, Posch LC, Orgel E, Liu DR, Dien Bard J. PMID: 41051777; PMCID: PMC12501814.
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    Translation:Humans
  7. Safety and efficacy of apixaban thrombosis prevention in pediatric patients with obesity and acute lymphoblastic leukemia. Blood Adv. 2025 Sep 23; 9(18):4738-4747. Rodriguez V, O'Brien SH, Orgel E, Schultz CL, Esbenshade AJ, Memaj A, Dyme JL, Favatella NA, Mitchell LG. PMID: 40505060; PMCID: PMC12496241.
    View in: PubMed Mentions: 2 Fields:
    Translation:Humans
  8. Adipocytes Impair Mitoxantrone Cytotoxicity Against Acute Lymphoblastic Leukemia. EJHaem. 2025 Oct; 6(5):e70140. Cohen M, Orgel E, Nevarez-Mejia J, Chen T, Neely M, Louie S, Mittelman SD. PMID: 40896243; PMCID: PMC12397950.
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  9. Factors Associated With Symptom Burden Among Pediatric Patients With Cancer. JCO Oncol Pract. 2025 Aug 14; OP2500244. Yan AP, Dupuis LL, Aftandilian C, Agarwal V, Baggott C, Beauchemin MP, Bradfield SM, Cannone D, Caywood EH, Crellin-Parsons N, Demedis J, Dickens D, Esbenshade AJ, Freyer DR, Grimes AC, Kelly KM, King AA, Klesges LM, Kyono W, Nagasubramanian R, Orgel E, Orsey AD, Roth ME, Sherani F, Vettese E, Walsh A, Woods-Swafford W, Yu LC, Tomlinson GA, Sung L. PMID: 40811761; PMCID: PMC12393674.
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  10. Clinical outcomes and interventions related to sedentary behaviours in childhood, adolescent, and young adult cancer patients and survivors: a scoping review protocol. BMJ Open. 2025 Aug 11; 15(8):e100965. Ivory BJ, Moore K, Dinalo JE, Ness KK, Orgel E, Dieli-Conwright CM, Kadan-Lottick NS, Freyer DR, Belcher BR. PMID: 40789725; PMCID: PMC12352156.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  11. Factors Associated With Self-Report Symptom Screening Adherence in Pediatric Cancer Patients. Cancer Med. 2025 Jul; 14(14):e71053. Dupuis LL, Vettese E, Aftandilian C, Agarwal V, Baggott C, Bradfield SM, Crellin-Parsons N, Freyer DR, Kelly KM, King AA, Kyono W, Nagasubramanian R, Orgel E, Roth ME, Sherani F, Yu L, Grimes AC, Beauchemin MP, Klesges LM, Tomlinson GA, Sung L. PMID: 40686265; PMCID: PMC12277931.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  12. Metabolic Implications of Childhood Cancer. Curr Pediatr Rep. 2025; 13. Tan J, Shabane B, Orgel E, Mittelman SD. PMID: 41676454; PMCID: PMC12890196.
    View in: PubMed Mentions: 1
  13. Development and Validation of a Novel Prediction Model for Hearing Loss From Cisplatin Chemotherapy. J Clin Oncol. 2025 Jul; 43(19):2173-2183. Millstein J, Rassekh SR, Brown AL, Nie Q, Esbenshade AJ, Knight KR, Scheurer ME, Sung L, Brooks B, Moke DJ, Ross CJD, Wright M, Mena V, Rushing T, Carleton BC, Orgel E. PMID: 40324146; PMCID: PMC12202178.
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    Translation:Humans
  14. Asparaginase dosing for acute lymphoblastic leukemia: more questions than answers. Haematologica. 2025 Aug 01; 110(8):1670-1672. Orgel E. PMID: 40270204; PMCID: PMC12358769.
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  15. Care Pathway- and Guideline-Consistent Care in Pediatric Cancer Symptom Management. JCO Oncol Pract. 2026 Feb; 22(2):235-242. Crellin-Parsons N, Dupuis LL, Vettese E, Aftandilian C, Agarwal V, Baggott C, Bradfield SM, Freyer DR, Kelly KM, King AA, Kyono W, Nagasubramanian R, Orgel E, Roth ME, Sherani F, Yu L, Grimes AC, Beauchemin MP, Klesges LM, Tomlinson GA, Sung L. PMID: 40267372; PMCID: PMC12353776.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  16. Practice patterns in the diagnosis and management of chemotherapy-induced peripheral neuropathy in adolescents and young adults with cancer: a survey of oncologists. Support Care Cancer. 2025 Apr 04; 33(4):350. Belsky JA, Dupuis LL, Sung L, Carter A, Leisinger A, Orgel E, Parsons SK, Roth M. PMID: 40183879; PMCID: PMC11971165.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  17. Feasibility and Safety of Intratympanic Administration of Sustained-Exposure Dexamethasone Thermosensitive Gel (OTO-104) for Prevention of Cisplatin-Induced Hearing Loss in Children: A Multisite Phase 2 Randomized Clinical Trial. Pediatr Blood Cancer. 2025 Jun; 72(6):e31680. Freyer DR, Ohlsen TJD, Don D, Orgel E, Hayashi RJ, Lieu JE, Foster JH, Sitton MS, Geller JI, Choo DI, Rangaswami A, Chang KW, Greffe B, Chan K, Lee A, Grunstein E, O'Neill AF, Rahbar R, Anderson JJ. PMID: 40128126.
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    Translation:HumansCTClinical Trials
  18. Real-World Experience Using Sodium Thiosulfate Pentahydrate Off-Label for Cisplatin Otoprotection in Children, Adolescents, and Young Adults. Pediatr Blood Cancer. 2025 May; 72(5):e31631. Ma J, Foster JH, Rassekh SR, Malvar J, Chi YY, Sauer HE, Jeon J, Freyer DR, Rushing T, Orgel E. PMID: 40032793.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  19. Prevention and Management of Infectious Complications in Pediatric Patients With Cancer: A Survey Assessment of Current Practices Across Children's Oncology Group Institutions. Pediatr Blood Cancer. 2025 Mar; 72(3):e31532. Slatnick LR, Hoogstra D, Fisher BT, Wolf J, Orgel E, Nessle CN, Patel PA, Miller TP, Wilkes J, Dupuis LL, Goode E, Jackson K, Willis DN, Elgarten C, Aftandilian C, Thompson J, Alexander S, Beauchemin MP, Belsky JA, Hess J, Prudowsky ZD, Guinipero T, Rossoff J, Demedis J, Walsh AM, Richards R, Choi DK, Dvorak CC, Esbenshade AJ. PMID: 39780366; PMCID: PMC12227264.
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    Translation:Humans
  20. Symptom Screening Linked to Care Pathways for Pediatric Patients With Cancer: A Randomized Clinical Trial. JAMA. 2024 12 17; 332(23):1981-1991. Dupuis LL, Vettese E, Grimes AC, Beauchemin MP, Klesges LM, Baggott C, Demedis J, Aftandilian C, Freyer DR, Crellin-Parsons N, Orgel E, Dickens D, Kelly KM, Kyono W, Walsh A, Sherani F, Cannone D, Orsey AD, King AA, Yu L, Woods-Swafford W, Bradfield SM, Roth ME, Esbenshade AJ, Caywood EH, Agarwal V, Nagasubramanian R, Tomlinson GA, Sung L. PMID: 39535768; PMCID: PMC11561721.
    View in: PubMed Mentions: 11 Fields:
    Translation:HumansCTClinical Trials
  21. Calaspargase pegol and pegaspargase cause similar hepatosteatosis in mice. Haematologica. 2025 Apr 01; 110(4):1019-1022. Ruiz-Torres V, Chia JJ, Cohen M, Tan J, Rushing T, Tinajero J, Orgel E, Mittelman SD. PMID: 39568437; PMCID: PMC11959228.
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  22. Prospective External Validation of the Esbenshade Vanderbilt Models Accurately Predicts Bloodstream Infection Risk in Febrile Non-Neutropenic Children With Cancer. J Clin Oncol. 2024 Mar 01; 42(7):832-841. Zhao Z, Patel PA, Slatnick L, Sitthi-Amorn A, Bielamowicz KJ, Nunez FA, Walsh AM, Hess J, Rossoff J, Elgarten C, Myers R, Saab R, Basbous M, Mccormick M, Aftandilian C, Richards R, Nessle CN, Tribble AC, Sheth Bhutada JK, Coven SL, Runco D, Wilkes J, Gurunathan A, Guinipero T, Belsky JA, Lee K, Wong V, Malhotra M, Armstrong A, Jerkins LP, Cross SJ, Fisher L, Stein MT, Wu NL, Yi T, Orgel E, Haeusler GM, Wolf J, Demedis JM, Miller TP, Esbenshade AJ. PMID: 38060973; PMCID: PMC10906655.
    View in: PubMed Mentions: 7 Fields:
    Translation:Humans
  23. An Exome Capture-Based RNA-Sequencing Assay for Genome-Wide Identification and Prioritization of Clinically Important Fusions in Pediatric Tumors. J Mol Diagn. 2024 02; 26(2):127-139. Buckley J, Schmidt RJ, Ostrow D, Maglinte D, Bootwalla M, Ruble D, Govindarajan A, Ji J, Kovach AE, Orgel E, Raca G, Navid F, Mascarenhas L, Pawel B, Robison N, Gai X, Biegel JA. PMID: 38008288.
    View in: PubMed Mentions: 2 Fields:
    Translation:Humans
  24. Apixaban versus no anticoagulation for the prevention of venous thromboembolism in children with newly diagnosed acute lymphoblastic leukaemia or lymphoma (PREVAPIX-ALL): a phase 3, open-label, randomised, controlled trial. Lancet Haematol. 2024 Jan; 11(1):e27-e37. O'Brien SH, Rodriguez V, Lew G, Newburger JW, Schultz CL, Orgel E, Derr K, Ranalli MA, Esbenshade AJ, Hochberg J, Kang HJ, Dinikina Y, Mills D, Donovan M, Dyme JL, Favatella NA, Mitchell LG, PREVAPIX-ALL investigators. PMID: 37980924.
    View in: PubMed Mentions: 18 Fields:
    Translation:HumansCTClinical Trials
  25. Lack of benefit from premedication for pegylated asparaginase during pediatric acute lymphoblastic leukemia/lymphoma therapy: A side-by-side comparison. Pediatr Blood Cancer. 2024 Jan; 71(1):e30716. Menig S, Dinh A, Angus J, Tucker S, Leger KJ, Rushing T, Orgel E. PMID: 37856184.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  26. Dose-limiting mucositis: friend or foe? Support Care Cancer. 2023 Oct 07; 31(10):617. Thornton CP, Orgel E. PMID: 37804322.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  27. Reevaluation of sodium thiosulfate otoprotection using the consensus International Society of Paediatric Oncology Ototoxicity Scale: A report from the Children's Oncology Group study ACCL0431. Pediatr Blood Cancer. 2023 Jul 07; e30550. Orgel E, Knight KR, Villaluna D, Krailo M, Esbenshade AJ, Sung L, Freyer DR. PMID: 37416942; PMCID: PMC10771531.
    View in: PubMed Mentions: 3 Fields:
  28. Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial. Clin Cancer Res. 2023 07 05; 29(13):2410-2418. Orgel E, Knight KR, Chi YY, Malvar J, Rushing T, Mena V, Eisenberg LS, Rassekh SR, Ross CJD, Scott EN, Neely M, Neuwelt EA, Muldoon LL, Freyer DR. PMID: 37134194; PMCID: PMC10330342.
    View in: PubMed Mentions: 16 Fields:
    Translation:HumansCTClinical Trials
  29. The International Consensus Classification of acute leukemias of ambiguous lineage. Blood. 2023 05 04; 141(18):2275-2277. Weinberg OK, Arber DA, Döhner H, Mullighan CG, Orgel E, Porwit A, Stone RM, Borowitz MJ. PMID: 36877915.
    View in: PubMed Mentions: 15 Fields:
    Translation:Humans
  30. Efficacy and safety of FLAG-IDA as front-line therapy in de novo paediatric acute myeloid leukaemia population. Br J Haematol. 2023 07; 202(1):e3-e6. Doan A, Huang HKT, Hadar AJ, Malvar J, Rushing T, Raca G, Kovach AE, Freyer DR, Parekh C, Stokke J, Posch LC, Dao J, Bhojwani D, Gaynon P, Orgel E. PMID: 37129267; PMCID: PMC10330637.
    View in: PubMed Mentions: 2 Fields:
    Translation:Humans
  31. Symptom management care pathway adaptation process and specific adaptation decisions. BMC Cancer. 2023 Apr 17; 23(1):350. Vettese E, Sherani F, King AA, Yu L, Aftandilian C, Baggott C, Agarwal V, Nagasubramanian R, Kelly KM, Freyer DR, Orgel E, Bradfield SM, Kyono W, Roth M, Klesges LM, Beauchemin M, Grimes A, Tomlinson G, Dupuis LL, Sung L. PMID: 37069510; PMCID: PMC10108500.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansCTClinical Trials
  32. Special considerations in the design and implementation of pediatric otoprotection trials. J Cancer Surviv. 2023 02; 17(1):4-16. Freyer DR, Orgel E, Knight K, Krailo M. PMID: 36637630.
    View in: PubMed Mentions: 10 Fields:
    Translation:Humans
  33. Asparaginase toxicity in Hispanic adult and pediatric patients with acute lymphoblastic leukemia: current understanding. Expert Opin Drug Metab Toxicol. 2023 Jan-Jun; 19(6):357-366. Alqahtani A, Alhousari D, Ali A, Yaghmour G, Orgel E, Curran E, Stock W, Bhojwani D, Alachkar H. PMID: 37410014; PMCID: PMC11516125.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  34. From soup to nuts: Obesity impairs chemotherapy during early and late phases of acute lymphoblastic leukemia treatment. Cancer. 2023 01 01; 129(1):15-17. Orgel E, Mittelman SD. PMID: 36369919.
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    Translation:Humans
  35. Temsirolimus combined with cyclophosphamide and etoposide for pediatric patients with relapsed/refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium trial (TACL 2014-001). Haematologica. 2022 10 01; 107(10):2295-2303. Tasian SK, Silverman LB, Whitlock JA, Sposto R, Loftus JP, Schafer ES, Schultz KR, Hutchinson RJ, Gaynon PS, Orgel E, Bateman CM, Cooper TM, Laetsch TW, Sulis ML, Chi YY, Malvar J, Wayne AS, Rheingold SR. PMID: 35112552; PMCID: PMC9521241.
    View in: PubMed Mentions: 12 Fields:
    Translation:HumansCTClinical Trials
  36. Sodium thiosulfate for prevention of cisplatin-induced hearing loss: updated survival from ACCL0431. Lancet Oncol. 2022 05; 23(5):570-572. Orgel E, Villaluna D, Krailo MD, Esbenshade A, Sung L, Freyer DR. PMID: 35489339; PMCID: PMC9635495.
    View in: PubMed Mentions: 17 Fields:
    Translation:Humans
  37. Erratum to: Cohen-Cutler S, Wong K, Mena V, et al. Hearing Loss Risk in Pediatric Patients Treated with Cranial Irradiation and Cisplatin-Based Chemotherapy. Int J Radiat Oncol Biol Phys 2021:110(5);1488-1495. Int J Radiat Oncol Biol Phys. 2022 Mar 01; 112(3):838-839. Cohen-Cutler S, Wong K, Mena V, Sianto K, Wright MA, Olch A, Orgel E. PMID: 35101201.
    View in: PubMed Mentions: Fields:
  38. Levocarnitine for pegaspargase-induced hepatotoxicity in older children and young adults with acute lymphoblastic leukemia. Cancer Med. 2021 11; 10(21):7551-7560. Schulte R, Hinson A, Huynh V, Breese EH, Pierro J, Rotz S, Mixon BA, McNeer JL, Burke MJ, Orgel E. PMID: 34528411; PMCID: PMC8559504.
    View in: PubMed Mentions: 14 Fields:
    Translation:Humans
  39. A Meta-analysis of the Utility of Red Cell Distribution Width as a Biomarker to Predict Outcomes in Pediatric Illness (PROSPERO CRD42020208777). J Pediatr Intensive Care. 2024 Dec; 13(4):307-314. Murphy D, Orgel E, Koek W, Frei-Jones M, Denton C, Kamat D. PMID: 39629347; PMCID: PMC11584274.
    View in: PubMed Mentions: 1
  40. Ultra-High Dose Vitamin D in Pediatric Hematopoietic Stem Cell Transplantation: A Nonrandomized Controlled Trial. Transplant Cell Ther. 2021 12; 27(12):1001.e1-1001.e9. Bhandari R, Aguayo-Hiraldo P, Malvar J, Cheng K, Sacapano A, Abdel-Azim H, Chi YY, Wallace G, Asgharzadeh S, Jodele S, Orgel E. PMID: 34500127.
    View in: PubMed Mentions: 6 Fields:
    Translation:Humans
  41. Increased prevalence of CRLF2 rearrangements in obesity-associated acute lymphoblastic leukemia. Blood. 2021 07 15; 138(2):199-202. Mittelman SD, Kim J, Raca G, Li G, Oberley MJ, Orgel E. PMID: 33876219; PMCID: PMC8288656.
    View in: PubMed Mentions: 10 Fields:
    Translation:Humans
  42. Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells. Front Oncol. 2021; 11:665763. Tucci J, Chen T, Margulis K, Orgel E, Paszkiewicz RL, Cohen MD, Oberley MJ, Wahhab R, Jones AE, Divakaruni AS, Hsu CC, Noll SE, Sheng X, Zare RN, Mittelman SD. PMID: 33968771; PMCID: PMC8100891.
    View in: PubMed Mentions: 34
  43. Caloric and nutrient restriction to augment chemotherapy efficacy for acute lymphoblastic leukemia: the IDEAL trial. Blood Adv. 2021 04 13; 5(7):1853-1861. Orgel E, Framson C, Buxton R, Kim J, Li G, Tucci J, Freyer DR, Sun W, Oberley MJ, Dieli-Conwright C, Mittelman SD. PMID: 33792627; PMCID: PMC8045487.
    View in: PubMed Mentions: 29 Fields:
    Translation:HumansCTClinical Trials
  44. Hearing Loss Risk in Pediatric Patients Treated with Cranial Irradiation and Cisplatin-Based Chemotherapy. Int J Radiat Oncol Biol Phys. 2021 08 01; 110(5):1488-1495. Cohen-Cutler S, Wong K, Mena V, Sianto K, Wright MA, Olch A, Orgel E. PMID: 33677052; PMCID: PMC8286302.
    View in: PubMed Mentions: 3 Fields:
    Translation:Humans
  45. Prevalence and risk factors for cisplatin-induced hearing loss in children, adolescents, and young adults: a multi-institutional North American cohort study. Lancet Child Adolesc Health. 2021 04; 5(4):274-283. Moke DJ, Luo C, Millstein J, Knight KR, Rassekh SR, Brooks B, Ross CJD, Wright M, Mena V, Rushing T, Esbenshade AJ, Carleton BC, Orgel E. PMID: 33581749; PMCID: PMC9059427.
    View in: PubMed Mentions: 35 Fields:
    Translation:Humans
  46. Mixed Phenotype Acute Leukemia: Current Approaches to Diagnosis and Treatment. Curr Oncol Rep. 2021 02 05; 23(2):22. Alexander TB, Orgel E. PMID: 33544265.
    View in: PubMed Mentions: 25 Fields:
    Translation:Humans
  47. Effect of Body Fat on Population Pharmacokinetics of High-Dose Methotrexate in Pediatric Patients With Acute Lymphoblastic Leukemia. J Clin Pharmacol. 2021 06; 61(6):755-762. Orgel E, Nabais T, Douglas C, Mittelman SD, Neely M. PMID: 33314168.
    View in: PubMed Mentions: 9 Fields:
    Translation:Humans
  48. Association of body mass index with toxicity and survival in pediatric patients treated with cisplatin-containing regimens. Pediatr Hematol Oncol. 2021 Apr; 38(3):239-250. Bhandari R, Scott E, Yeh MY, Wong K, Rushing T, Huh W, Orgel E. PMID: 33170064; PMCID: PMC8439118.
    View in: PubMed Mentions: 3 Fields:
    Translation:Humans
  49. Preexisting or therapy-induced mutations in relapsed acute lymphoblastic leukemia? Blood. 2020 11 05; 136(19):2233-2235. Gaynon PS, Orgel E, Ji L. PMID: 32603411.
    View in: PubMed Mentions: 2 Fields:
    Translation:Humans
  50. Assessment of provider perspectives on otoprotection research for children and adolescents: A Children's Oncology Group Cancer Control and Supportive Care Committee survey. Pediatr Blood Cancer. 2020 11; 67(11):e28647. Orgel E, Freyer DR, Ullrich NJ, Hardy KK, Thomas SM, Dvorak CC, Esbenshade AJ. PMID: 32886425; PMCID: PMC7808411.
    View in: PubMed Mentions: 5 Fields:
    Translation:Humans
  51. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020 07 09; 136(2):210-223. Gang EJ, Kim HN, Hsieh YT, Ruan Y, Ogana HA, Lee S, Pham J, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, Parekh C, Abdel-Azim H, Bhojwani D, Wayne AS, De Arcangelis A, Georges-Labouesse E, Wayner E, Bonig H, Minasyan A, Ten Hoeve J, Graeber TG, Müschen M, Heisterkamp N, Kim YM. PMID: 32219444; PMCID: PMC7357190.
    View in: PubMed Mentions: 34 Fields:
    Translation:HumansAnimals
  52. Significance of minimal residual disease in pediatric mixed phenotype acute leukemia: a multicenter cohort study. Leukemia. 2020 07; 34(7):1741-1750. Oberley MJ, Raikar SS, Wertheim GB, Malvar J, Sposto R, Rabin KR, Punia JN, Seif AE, Cahen VC, Schore RJ, Luca DC, Guinipero T, Woods WG, O'Gorman MRG, Orgel E. PMID: 32060402; PMCID: PMC7332384.
    View in: PubMed Mentions: 9 Fields:
    Translation:Humans
  53. Clinical features and outcomes of patients with Shwachman-Diamond syndrome and myelodysplastic syndrome or acute myeloid leukaemia: a multicentre, retrospective, cohort study. Lancet Haematol. 2020 Mar; 7(3):e238-e246. Myers KC, Furutani E, Weller E, Siegele B, Galvin A, Arsenault V, Alter BP, Boulad F, Bueso-Ramos C, Burroughs L, Castillo P, Connelly J, Davies SM, DiNardo CD, Hanif I, Ho RH, Karras N, Manalang M, McReynolds LJ, Nakano TA, Nalepa G, Norkin M, Oberley MJ, Orgel E, Pastore YD, Rosenthal J, Walkovich K, Larson J, Malsch M, Elghetany MT, Fleming MD, Shimamura A. PMID: 31879230; PMCID: PMC7984274.
    View in: PubMed Mentions: 44 Fields:
    Translation:Humans
  54. Mixed-phenotype acute leukemia: A cohort and consensus research strategy from the Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task Force. Cancer. 2020 02 01; 126(3):593-601. Orgel E, Alexander TB, Wood BL, Kahwash SB, Devidas M, Dai Y, Alonzo TA, Mullighan CG, Inaba H, Hunger SP, Raetz EA, Gamis AS, Rabin KR, Carroll AJ, Heerema NA, Berman JN, Woods WG, Loh ML, Zweidler-McKay PA, Horan JT, Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task Force. PMID: 31661160; PMCID: PMC7489437.
    View in: PubMed Mentions: 20 Fields:
    Translation:Humans
  55. Association between Vitamin D and Risk for Early and Late Post-Transplant Complications. Biol Blood Marrow Transplant. 2020 02; 26(2):343-350. Bhandari R, Malvar J, Sacapano A, Aguayo-Hiraldo P, Jodele S, Orgel E. PMID: 31654787.
    View in: PubMed Mentions: 3 Fields:
    Translation:Humans
  56. Improving the Timeliness of Chemotherapy Administration in the Bone Marrow Transplant Unit. Biol Blood Marrow Transplant. 2020 01; 26(1):150-156. Bhandari R, Orgel E, Rushing T, Malicse K, Evangelista V, Jodele S, Dandoy CE. PMID: 31562961; PMCID: PMC7513385.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  57. Levocarnitine does not impair chemotherapy cytotoxicity against acute lymphoblastic leukemia. Leuk Lymphoma. 2020 02; 61(2):420-428. Sea JL, Orgel E, Chen T, Paszkiewicz RL, Krall AS, Oberley MJ, Stiles L, Mittelman SD. PMID: 31526067; PMCID: PMC7305023.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansAnimals
  58. Mechanisms by Which Obesity Impacts Survival from Acute Lymphoblastic Leukemia. J Natl Cancer Inst Monogr. 2019 09 01; 2019(54):152-156. Orgel E, Sea JL, Mittelman SD. PMID: 31532535; PMCID: PMC6750167.
    View in: PubMed Mentions: 26 Fields:
    Translation:HumansPHPublic Health
  59. Myosteatosis in adolescents and young adults treated for acute lymphoblastic leukemia. Leuk Lymphoma. 2019 12; 60(13):3146-3153. Mueske NM, Mittelman SD, Wren TAL, Gilsanz V, Orgel E. PMID: 31264493; PMCID: PMC6923569.
    View in: PubMed Mentions: 7 Fields:
    Translation:HumansCTClinical Trials
  60. Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium. Lancet Oncol. 2019 01; 20(1):e29-e41. Clemens E, van den Heuvel-Eibrink MM, Mulder RL, Kremer LCM, Hudson MM, Skinner R, Constine LS, Bass JK, Kuehni CE, Langer T, van Dalen EC, Bardi E, Bonne NX, Brock PR, Brooks B, Carleton B, Caron E, Chang KW, Johnston K, Knight K, Nathan PC, Orgel E, Prasad PK, Rottenberg J, Scheinemann K, de Vries ACH, Walwyn T, Weiss A, Am Zehnhoff-Dinnesen A, Cohn RJ, Landier W, International Guideline Harmonization Group ototoxicity group. PMID: 30614474; PMCID: PMC7549756.
    View in: PubMed Mentions: 50 Fields:
    Translation:HumansPHPublic Health
  61. The genetic basis and cell of origin of mixed phenotype acute leukaemia. Nature. 2018 10; 562(7727):373-379. Alexander TB, Gu Z, Iacobucci I, Dickerson K, Choi JK, Xu B, Payne-Turner D, Yoshihara H, Loh ML, Horan J, Buldini B, Basso G, Elitzur S, de Haas V, Zwaan CM, Yeoh A, Reinhardt D, Tomizawa D, Kiyokawa N, Lammens T, De Moerloose B, Catchpoole D, Hori H, Moorman A, Moore AS, Hrusak O, Meshinchi S, Orgel E, Devidas M, Borowitz M, Wood B, Heerema NA, Carrol A, Yang YL, Smith MA, Davidsen TM, Hermida LC, Gesuwan P, Marra MA, Ma Y, Mungall AJ, Moore RA, Jones SJM, Valentine M, Janke LJ, Rubnitz JE, Pui CH, Ding L, Liu Y, Zhang J, Nichols KE, Downing JR, Cao X, Shi L, Pounds S, Newman S, Pei D, Guidry Auvil JM, Gerhard DS, Hunger SP, Inaba H, Mullighan CG. PMID: 30209392; PMCID: PMC6195459.
    View in: PubMed Mentions: 180 Fields:
    Translation:HumansCells
  62. Adipocyte metabolism of the chemotherapy daunorubicin. Oncoscience. 2018 May; 5(5-6):146-147. Mittelman SD, Orgel E. PMID: 30035170; PMCID: PMC6049316.
    View in: PubMed Mentions: 4
  63. Obesity and risk for venous thromboembolism from contemporary therapy for pediatric acute lymphoblastic leukemia. Thromb Res. 2018 05; 165:44-50. Prasca S, Carmona R, Ji L, Ko RH, Bhojwani D, Rawlins YA, Mittelman SD, Young G, Orgel E. PMID: 29567586; PMCID: PMC7522001.
    View in: PubMed Mentions: 15 Fields:
    Translation:Humans
  64. Therapy for children and adults with mixed phenotype acute leukemia: a systematic review and meta-analysis. Leukemia. 2018 07; 32(7):1515-1528. Maruffi M, Sposto R, Oberley MJ, Kysh L, Orgel E. PMID: 29550836; PMCID: PMC7508489.
    View in: PubMed Mentions: 55 Fields:
    Translation:HumansAnimals
  65. Predictors of hepatotoxicity and pancreatitis in children and adolescents with acute lymphoblastic leukemia treated according to contemporary regimens. Pediatr Blood Cancer. 2018 03; 65(3). Denton CC, Rawlins YA, Oberley MJ, Bhojwani D, Orgel E. PMID: 29218844; PMCID: PMC7522002.
    View in: PubMed Mentions: 33 Fields:
    Translation:Humans
  66. TACL'ing supportive care needs in pediatric early phase clinical trials for acute leukemia: A report from the therapeutic advances in childhood leukemia & lymphoma (TACL) consortium supportive care committee. Pediatr Hematol Oncol. 2017 Sep - Oct; 34(6-7):409-417. Orgel E, Auletta JJ. PMID: 29190169; PMCID: PMC7513384.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  67. Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin. Mol Cancer Res. 2017 12; 15(12):1704-1713. Sheng X, Parmentier JH, Tucci J, Pei H, Cortez-Toledo O, Dieli-Conwright CM, Oberley MJ, Neely M, Orgel E, Louie SG, Mittelman SD. PMID: 29117945; PMCID: PMC5726435.
    View in: PubMed Mentions: 91 Fields:
    Translation:HumansCells
  68. Association of clinical trial enrollment and survival using contemporary therapy for pediatric acute lymphoblastic leukemia. Pediatr Blood Cancer. 2018 Feb; 65(2). Moke DJ, Oberley MJ, Bhojwani D, Parekh C, Orgel E. PMID: 28876513; PMCID: PMC7553364.
    View in: PubMed Mentions: 6 Fields:
    Translation:Humans
  69. Clinical Significance of Isolated Myeloperoxidase Expression in Pediatric B-Lymphoblastic Leukemia. Am J Clin Pathol. 2017 04 01; 147(4):374-381. Oberley MJ, Li S, Orgel E, Phei Wee C, Hagiya A, O'Gorman MRG. PMID: 28340210.
    View in: PubMed Mentions: 16 Fields:
    Translation:HumansCells
  70. A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia. Leuk Lymphoma. 2017 Oct; 58(10):2370-2378. Orgel E, Mueske NM, Sposto R, Gilsanz V, Wren TAL, Freyer DR, Butturini AM, Mittelman SD. PMID: 28278717; PMCID: PMC5489365.
    View in: PubMed Mentions: 10 Fields:
    Translation:Humans
  71. Treatment-related adverse events associated with a modified UK ALLR3 induction chemotherapy backbone for childhood relapsed/refractory acute lymphoblastic leukemia. Pediatr Blood Cancer. 2016 11; 63(11):1943-8. Sun W, Orgel E, Malvar J, Sposto R, Wilkes JJ, Gardner R, Tolbert VP, Smith A, Hur M, Hoffman J, Rheingold SR, Burke MJ, Wayne AS. PMID: 27437864; PMCID: PMC7451261.
    View in: PubMed Mentions: 17 Fields:
    Translation:Humans
  72. Association of body mass index and survival in pediatric leukemia: a meta-analysis. Am J Clin Nutr. 2016 Mar; 103(3):808-17. Orgel E, Genkinger JM, Aggarwal D, Sung L, Nieder M, Ladas EJ. PMID: 26864366; PMCID: PMC6546230.
    View in: PubMed Mentions: 77 Fields:
    Translation:Humans
  73. Early injury to cortical and cancellous bone from induction chemotherapy for adolescents and young adults treated for acute lymphoblastic leukemia. Bone. 2016 Apr; 85:131-7. Orgel E, Mueske NM, Wren TA, Gilsanz V, Butturini AM, Freyer DR, Mittelman SD. PMID: 26851412; PMCID: PMC4795805.
    View in: PubMed Mentions: 13 Fields:
    Translation:Humans
  74. Limitations of body mass index to assess body composition due to sarcopenic obesity during leukemia therapy. Leuk Lymphoma. 2018 01; 59(1):138-145. Orgel E, Mueske NM, Sposto R, Gilsanz V, Freyer DR, Mittelman SD. PMID: 26818609; PMCID: PMC5362342.
    View in: PubMed Mentions: 43 Fields:
    Translation:Humans
  75. Effect of Sensorineural Hearing Loss on Neurocognitive Functioning in Pediatric Brain Tumor Survivors. Pediatr Blood Cancer. 2016 Mar; 63(3):527-34. Orgel E, O'Neil SH, Kayser K, Smith B, Softley TL, Sherman-Bien S, Counts PA, Murphy D, Dhall G, Freyer DR. PMID: 26529035; PMCID: PMC4724248.
    View in: PubMed Mentions: 25 Fields:
    Translation:Humans
  76. Clinical and microbiologic outcomes of quinolone prophylaxis in children with acute myeloid leukemia. Pediatr Infect Dis J. 2015 Apr; 34(4):e78-84. Felsenstein S, Orgel E, Rushing T, Fu C, Hoffman JA. PMID: 25764103.
    View in: PubMed Mentions: 12 Fields:
    Translation:HumansCells
  77. Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia. Blood. 2014 Dec 18; 124(26):3932-8. Orgel E, Tucci J, Alhushki W, Malvar J, Sposto R, Fu CH, Freyer DR, Abdel-Azim H, Mittelman SD. PMID: 25349177.
    View in: PubMed Mentions: 60 Fields:
    Translation:Humans
  78. Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group. J Clin Oncol. 2014 May 01; 32(13):1331-7. Orgel E, Sposto R, Malvar J, Seibel NL, Ladas E, Gaynon PS, Freyer DR. PMID: 24687836; PMCID: PMC3992723.
    View in: PubMed Mentions: 76 Fields:
    Translation:Humans
  79. Infectious morbidity by catheter type in neutropenic children with cancer. Pediatr Infect Dis J. 2014 Mar; 33(3):263-6. Orgel E, Ji L, Pastor W, Schore RJ. PMID: 24263218.
    View in: PubMed Mentions: 4 Fields:
    Translation:Humans
  80. Efficacy and tolerability of intravenous pentamidine isethionate for Pneumocystis jiroveci prophylaxis in a pediatric oncology population. Pediatr Infect Dis J. 2014 Mar; 33(3):319-21. Orgel E, Rushing T. PMID: 24030353.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansAnimals
  81. Why Healthcare Providers Should Focus on the Fertility of AYA Cancer Survivors: It's Not Too Late! Front Oncol. 2013 Oct 07; 3:248. Murphy D, Orgel E, Termuhlen A, Shannon S, Warren K, Quinn GP. PMID: 24109589; PMCID: PMC3791875.
    View in: PubMed Mentions: 21
  82. The links between insulin resistance, diabetes, and cancer. Curr Diab Rep. 2013 Apr; 13(2):213-22. Orgel E, Mittelman SD. PMID: 23271574; PMCID: PMC3595327.
    View in: PubMed Mentions: 87 Fields:
    Translation:HumansAnimals
  83. Early cardiac outcomes following contemporary treatment for childhood acute myeloid leukemia: a North American perspective. Pediatr Blood Cancer. 2013 Sep; 60(9):1528-33. Orgel E, Zung L, Ji L, Finklestein J, Feusner J, Freyer DR. PMID: 23441080.
    View in: PubMed Mentions: 15 Fields:
    Translation:HumansCTClinical Trials
  84. Hearing loss among survivors of childhood brain tumors treated with an irradiation-sparing approach. Pediatr Blood Cancer. 2012 Jun; 58(6):953-8. Orgel E, Jain S, Ji L, Pollick L, Si S, Finlay J, Freyer DR. PMID: 21796767.
    View in: PubMed Mentions: 21 Fields:
    Translation:Humans
  85. A failing medical educational model: a self-assessment by physicians at all levels of training of ability and comfort to deliver bad news. J Palliat Med. 2010 Jun; 13(6):677-83. Orgel E, McCarter R, Jacobs S. PMID: 20597701.
    View in: PubMed Mentions: 26 Fields:
    Translation:Humans

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