Lin Zhang • USC Profiles (original) (raw)
- Reactivating necroptosis in colorectal cancer potentiates chemotherapy and antitumor immune responses. Cancer Lett. 2026 Jan 28; 638:218169. Ermine K, Chen D, Hao S, Liu Z, Lu X, Leibowitz BJ, Wang P, Jin Z, Schoen RE, Yu J, Zhang L. PMID: 41314503; PMCID: PMC12725768.
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Translation:HumansAnimalsCells - Understanding the Functional Dependence and Inhibition of the Bcl‑2 Pro-Survival Proteins in a Wide Spectrum of Cancers toward Precision Medicine. ACS Pharmacol Transl Sci. 2025 Sep 12; 8(9):2922-2935. Kump KJ, Ahmad E, Foucar C, Avelar RA, Murga-Zamalloa C, Lieberman M, Kandarpa M, Mady ASA, DiFeo A, Zhang L, Malek S, Phillips T, Wilcox R, Bixby D, Talpaz M, Nikolovska-Coleska Z. PMID: 40969874; PMCID: PMC12441837.
View in: PubMed Mentions: 2 - Pan-RAS inhibitors and polo-like kinase 1: promising targets in colorectal cancer. Oncogene. 2025 Aug; 44(30):2565-2573. Jayachandran P, Elliott A, Soni S, Battaglin F, Mittal P, Algaze S, Lo JH, Yang Y, Ashouri K, Roussos Torres ET, Zhang W, Millstein J, Zhang L, Yu J, Lenz HJ. PMID: 40615690; PMCID: PMC12277178.
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Translation:HumansAnimals - Depletion of oxysterol-binding proteins by OSW-1 triggers RIP1/RIP3-independent necroptosis and sensitization to cancer immunotherapy. Cell Death Differ. 2025 Nov; 32(11):2038-2052. Lu X, Chen D, Wang M, Song X, Ermine K, Hao S, Jha A, Huang Y, Kang Y, Qiu H, Lenz HJ, Li S, Jin Z, Yu J, Zhang L. PMID: 40329104; PMCID: PMC12572256.
View in: PubMed Mentions: 3 Fields:
Translation:HumansAnimalsCells - Differential Response and Resistance to KRAS-Targeted Therapy. Mol Carcinog. 2025 Jul; 64(7):1135-1148. Liu Z, Lenz HJ, Yu J, Zhang L. PMID: 40256920.
View in: PubMed Mentions: 2 Fields:
Translation:HumansAnimals - Werner helicase as a therapeutic target in mismatch repair deficient colorectal cancer. DNA Repair (Amst). 2025 05; 149:103831. Hao S, Liu Z, Lenz HJ, Yu J, Zhang L. PMID: 40203476; PMCID: PMC12086038.
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Translation:HumansAnimalsCells - Low extracellular pH enhances TRAIL-induced apoptosis by downregulating Mcl-1 expression. Exp Cell Res. 2025 Apr 01; 447(1):114481. Vafaeinik F, Zhang L, Lee YJ. PMID: 40024506; PMCID: PMC12340464.
View in: PubMed Mentions: 1 Fields:
Translation:HumansCells - Mcl-1 is a Gatekeeper Molecule to Regulate the Crosstalk Between Ferroptotic Agent-Induced ER Stress and TRAIL-Induced Apoptosis. J Cell Biochem. 2025 Jan; 126(1):e30681. Lee YS, Vafaeinik F, Mouakkad L, Kim DH, Song X, Zhang L, Lee YJ. PMID: 39853862; PMCID: PMC12218107.
View in: PubMed Mentions: 1 Fields:
Translation:HumansCells - Comprehensive characterization of MCL-1 in patients with colorectal cancer: Expression, molecular profiles, and outcomes. Int J Cancer. 2025 Apr 15; 156(8):1583-1593. Mittal P, Battaglin F, Baca Y, Xiu J, Farrell A, Soni S, Lo JH, Torres-Gonzalez L, Algaze S, Jayachandran P, Ashouri K, Wong A, Zhang W, Yu J, Zhang L, Weinberg BA, Lou E, Shields AF, Goldberg RM, Marshall JL, Goel S, Singh IK, Lenz HJ. PMID: 39740007; PMCID: PMC11826129.
View in: PubMed Mentions: 2 Fields:
Translation:HumansCells - UNSEG: unsupervised segmentation of cells and their nuclei in complex tissue samples. Commun Biol. 2024 08 30; 7(1):1062. Kochetov B, Bell PD, Garcia PS, Shalaby AS, Raphael R, Raymond B, Leibowitz BJ, Schoedel K, Brand RM, Brand RE, Yu J, Zhang L, Diergaarde B, Schoen RE, Singhi A, Uttam S. PMID: 39215205; PMCID: PMC11364851.
View in: PubMed Mentions: 3 Translation:HumansCells - Restoration of TFPI2 by LSD1 inhibition suppresses tumor progression and potentiates antitumor immunity in breast cancer. Cancer Lett. 2024 Sep 28; 600:217182. Gu T, Vasilatos SN, Yin J, Qin Y, Zhang L, Davidson NE, Huang Y. PMID: 39154703; PMCID: PMC11384719.
View in: PubMed Mentions: 6 Fields:
Translation:HumansAnimalsCells - PUMA/RIP3 Mediates Chemotherapy Response via Necroptosis and Local Immune Activation in Colorectal Cancer. Mol Cancer Ther. 2024 Mar 04; 23(3):354-367. Chen D, Ermine K, Wang YJ, Chen X, Lu X, Wang P, Beer-Stolz D, Yu J, Zhang L. PMID: 37992761; PMCID: PMC10932881.
View in: PubMed Mentions: 8 Fields:
Translation:Humans - mTOR inhibition suppresses Myc-driven polyposis by inducing immunogenic cell death. Oncogene. 2023 06; 42(24):2007-2016. Leibowitz BJ, Zhao G, Xia W, Wang Y, Ruan H, Zhang L, Yu J. PMID: 37138032; PMCID: PMC10256613.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimalsCells - Targeting Myc-driven stress addiction in colorectal cancer. Drug Resist Updat. 2023 07; 69:100963. Saeed H, Leibowitz BJ, Zhang L, Yu J. PMID: 37119690; PMCID: PMC10330748.
View in: PubMed Mentions: 24 Fields:
Translation:Humans - Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction. Oncogene. 2023 03; 42(12):869-880. Tong J, Tan X, Hao S, Ermine K, Lu X, Liu Z, Jha A, Yu J, Zhang L. PMID: 36721000; PMCID: PMC10364554.
View in: PubMed Mentions: 5 Fields:
Translation:HumansCells - Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer. Proc Natl Acad Sci U S A. 2022 12 20; 119(51):e2211775119. Hao S, Tong J, Jha A, Risnik D, Lizardo D, Lu X, Goel A, Opresko PL, Yu J, Zhang L. PMID: 36508676; PMCID: PMC9907101.
View in: PubMed Mentions: 16 Fields:
Translation:Humans - Dual inhibition of BET and HAT/p300 suppresses colorectal cancer via DR5- and p53/PUMA-mediated cell death. Front Oncol. 2022; 12:1018775. Kuang C, Tong J, Ermine K, Cai M, Dai F, Hao S, Giles F, Huang Y, Yu J, Zhang L. PMID: 36313707; PMCID: PMC9599411.
View in: PubMed Mentions: 4 - CDK4/6 Inhibition Suppresses p73 Phosphorylation and Activates DR5 to Potentiate Chemotherapy and Immune Checkpoint Blockade. Cancer Res. 2022 04 01; 82(7):1340-1352. Tong J, Tan X, Song X, Gao M, Risnik D, Hao S, Ermine K, Wang P, Li H, Huang Y, Yu J, Zhang L. PMID: 35149588; PMCID: PMC8983601.
View in: PubMed Mentions: 20 Fields:
Translation:HumansCells - Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer. Mol Biomed. 2022 Mar 21; 3(1):10. Ruan H, Leibowitz BJ, Peng Y, Shen L, Chen L, Kuang C, Schoen RE, Lu X, Zhang L, Yu J. PMID: 35307764; PMCID: PMC8934835.
View in: PubMed Mentions: 7 Fields: - Role of Receptor Interacting Protein (RIP) kinases in cancer. Genes Dis. 2022 Nov; 9(6):1579-1593. Ermine K, Yu J, Zhang L. PMID: 36157481; PMCID: PMC9485196.
View in: PubMed Mentions: 11 - BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade. Oncogene. 2021 12; 40(48):6566-6578. Tong J, Tan X, Risnik D, Gao M, Song X, Ermine K, Shen L, Wang S, Yu J, Zhang L. PMID: 34615996; PMCID: PMC8642302.
View in: PubMed Mentions: 17 Fields:
Translation:HumansAnimalsCells - Interferon b drives intestinal regeneration after radiation. Sci Adv. 2021 Oct 08; 7(41):eabi5253. Leibowitz BJ, Zhao G, Wei L, Ruan H, Epperly M, Chen L, Lu X, Greenberger JS, Zhang L, Yu J. PMID: 34613772; PMCID: PMC8494436.
View in: PubMed Mentions: 31 Fields: - Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis. Oncogene. 2021 03; 40(11):2035-2050. Fletcher R, Tong J, Risnik D, Leibowitz BJ, Wang YJ, Concha-Benavente F, DeLiberty JM, Stolz DB, Pai RK, Ferris RL, Schoen RE, Yu J, Zhang L. PMID: 33603166; PMCID: PMC7981263.
View in: PubMed Mentions: 17 Fields:
Translation:HumansAnimalsCells - Glucose deprivation-induced endoplasmic reticulum stress response plays a pivotal role in enhancement of TRAIL cytotoxicity. J Cell Physiol. 2021 09; 236(9):6666-6677. Kalimuthu K, Kim JH, Park YS, Luo X, Zhang L, Ku JL, Choudry MHA, Lee YJ. PMID: 33586156; PMCID: PMC11572546.
View in: PubMed Mentions: 14 Fields:
Translation:HumansCells - A novel immunochemotherapy based on targeting of cyclooxygenase and induction of immunogenic cell death. Biomaterials. 2021 03; 270:120708. Huang H, Huang Y, Chen Y, Luo Z, Zhang Z, Sun R, Wan Z, Sun J, Lu B, Zhang L, Hu J, Li S. PMID: 33578254; PMCID: PMC7910750.
View in: PubMed Mentions: 9 Fields:
Translation:AnimalsCells - eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis. Elife. 2020 11 02; 9. Ruan H, Li X, Xu X, Leibowitz BJ, Tong J, Chen L, Ao L, Xing W, Luo J, Yu Y, Schoen RE, Sonenberg N, Lu X, Zhang L, Yu J. PMID: 33135632; PMCID: PMC7665890.
View in: PubMed Mentions: 22 Fields:
Translation:HumansAnimalsCells - Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedside. Biochim Biophys Acta Rev Cancer. 2020 12; 1874(2):188447. Lizardo DY, Kuang C, Hao S, Yu J, Huang Y, Zhang L. PMID: 33035640; PMCID: PMC7886024.
View in: PubMed Mentions: 123 Fields:
Translation:HumansCells - Mcl-1 inhibition overcomes intrinsic and acquired regorafenib resistance in colorectal cancer. Theranostics. 2020; 10(18):8098-8110. Song X, Shen L, Tong J, Kuang C, Zeng S, Schoen RE, Yu J, Pei H, Zhang L. PMID: 32724460; PMCID: PMC7381732.
View in: PubMed Mentions: 44 Fields:
Translation:HumansAnimalsCells - Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis. Nat Commun. 2020 04 20; 11(1):1899. Xu J, Ma H, Ma H, Jiang W, Mela CA, Duan M, Zhao S, Gao C, Hahm ER, Lardo SM, Troy K, Sun M, Pai R, Stolz DB, Zhang L, Singh S, Brand RE, Hartman DJ, Hu J, Hainer SJ, Liu Y. PMID: 32313005; PMCID: PMC7171144.
View in: PubMed Mentions: 61 Fields:
Translation:HumansAnimalsCells - Immunogenic cell death in colon cancer prevention and therapy. Mol Carcinog. 2020 07; 59(7):783-793. Ruan H, Leibowitz BJ, Zhang L, Yu J. PMID: 32215970; PMCID: PMC7593824.
View in: PubMed Mentions: 71 Fields:
Translation:HumansAnimalsCells - Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer. Theranostics. 2020; 10(1):265-280. Deng X, Li S, Kong F, Ruan H, Xu X, Zhang X, Wu Z, Zhang L, Xu Y, Yuan H, Peng H, Yang D, Guan M. PMID: 31903119; PMCID: PMC6929633.
View in: PubMed Mentions: 38 Fields:
Translation:HumansCells - High Loading of Hydrophobic and Hydrophilic Agents via Small Immunostimulatory Carrier for Enhanced Tumor Penetration and Combinational Therapy. Theranostics. 2020; 10(3):1136-1150. Sun J, Chen Y, Xu J, Song X, Wan Z, Du Y, Ma W, Li X, Zhang L, Li S. PMID: 31938056; PMCID: PMC6956803.
View in: PubMed Mentions: 18 Fields:
Translation:HumansAnimalsCells - p53 Up-regulated Modulator of Apoptosis Induction Mediates Acetaminophen-Induced Necrosis and Liver Injury in Mice. Hepatology. 2019 05; 69(5):2164-2179. Chen D, Ni HM, Wang L, Ma X, Yu J, Ding WX, Zhang L. PMID: 30552702; PMCID: PMC6461480.
View in: PubMed Mentions: 46 Fields:
Translation:AnimalsCells - BET Inhibitors Potentiate Chemotherapy and Killing of SPOP-Mutant Colon Cancer Cells via Induction of DR5. Cancer Res. 2019 03 15; 79(6):1191-1203. Tan X, Tong J, Wang YJ, Fletcher R, Schoen RE, Yu J, Shen L, Zhang L. PMID: 30674532; PMCID: PMC6420862.
View in: PubMed Mentions: 37 Fields:
Translation:HumansAnimalsCells - Mcl-1 Phosphorylation without Degradation Mediates Sensitivity to HDAC Inhibitors by Liberating BH3-Only Proteins. Cancer Res. 2018 08 15; 78(16):4704-4715. Tong J, Zheng X, Tan X, Fletcher R, Nikolovska-Coleska Z, Yu J, Zhang L. PMID: 29895675; PMCID: PMC6298746.
View in: PubMed Mentions: 42 Fields:
Translation:HumansCells - Immunogenic effects of chemotherapy-induced tumor cell death. Genes Dis. 2018 Sep; 5(3):194-203. Wang YJ, Fletcher R, Yu J, Zhang L. PMID: 30320184; PMCID: PMC6176216.
View in: PubMed Mentions: 166 - Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer. Oncogene. 2018 08; 37(33):4599-4610. Knickelbein K, Tong J, Chen D, Wang YJ, Misale S, Bardelli A, Yu J, Zhang L. PMID: 29755130; PMCID: PMC6195818.
View in: PubMed Mentions: 27 Fields:
Translation:HumansAnimalsCells - PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors. Proc Natl Acad Sci U S A. 2018 04 10; 115(15):3930-3935. Chen D, Tong J, Yang L, Wei L, Stolz DB, Yu J, Zhang J, Zhang L. PMID: 29581256; PMCID: PMC5899441.
View in: PubMed Mentions: 111 Fields:
Translation:HumansAnimalsCells - Targeting p53-dependent stem cell loss for intestinal chemoprotection. Sci Transl Med. 2018 02 07; 10(427). Leibowitz BJ, Yang L, Wei L, Buchanan ME, Rachid M, Parise RA, Beumer JH, Eiseman JL, Schoen RE, Zhang L, Yu J. PMID: 29437148; PMCID: PMC5827930.
View in: PubMed Mentions: 39 Fields:
Translation:AnimalsCells - The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice. Sci Rep. 2018 02 01; 8(1):2072. Wei L, Leibowitz BJ, Epperly M, Bi C, Li A, Steinman J, Wipf P, Li S, Zhang L, Greenberger J, Yu J. PMID: 29391546; PMCID: PMC5794877.
View in: PubMed Mentions: 15 Fields:
Translation:AnimalsCellsPHPublic Health - Colorectal cancer prevention: Immune modulation taking the stage. Biochim Biophys Acta Rev Cancer. 2018 Apr; 1869(2):138-148. Fletcher R, Wang YJ, Schoen RE, Finn OJ, Yu J, Zhang L. PMID: 29391185; PMCID: PMC5955808.
View in: PubMed Mentions: 42 Fields:
Translation:HumansAnimals - The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity. Cell Rep. 2017 08 15; 20(7):1692-1704. Xie Y, Zhu S, Song X, Sun X, Fan Y, Liu J, Zhong M, Yuan H, Zhang L, Billiar TR, Lotze MT, Zeh HJ, Kang R, Kroemer G, Tang D. PMID: 28813679.
View in: PubMed Mentions: 539 Fields:
Translation:HumansAnimalsCells - FBW7-Dependent Mcl-1 Degradation Mediates the Anticancer Effect of Hsp90 Inhibitors. Mol Cancer Ther. 2017 09; 16(9):1979-1988. Tong J, Tan S, Nikolovska-Coleska Z, Yu J, Zou F, Zhang L. PMID: 28619760; PMCID: PMC5587378.
View in: PubMed Mentions: 48 Fields:
Translation:HumansAnimalsCells - Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells. Cancer Res. 2017 05 01; 77(9):2512-2521. Tong J, Wang P, Tan S, Chen D, Nikolovska-Coleska Z, Zou F, Yu J, Zhang L. PMID: 28202514; PMCID: PMC5626525.
View in: PubMed Mentions: 91 Fields:
Translation:HumansAnimalsCells - Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress. Oncotarget. 2017 Feb 07; 8(6):9280-9292. Li X, Li M, Ruan H, Qiu W, Xu X, Zhang L, Yu J. PMID: 28030835; PMCID: PMC5354731.
View in: PubMed Mentions: 10 Fields:
Translation:HumansAnimalsCells - 5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers. J Immunother Cancer. 2016; 4:65. Van Der Kraak L, Goel G, Ramanan K, Kaltenmeier C, Zhang L, Normolle DP, Freeman GJ, Tang D, Nason KS, Davison JM, Luketich JD, Dhupar R, Lotze MT. PMID: 27777774; PMCID: PMC5067917.
View in: PubMed Mentions: 74 Fields:
Translation:HumansCells - Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice. J Clin Invest. 2016 11 01; 126(11):4076-4087. Wei L, Leibowitz BJ, Wang X, Epperly M, Greenberger J, Zhang L, Yu J. PMID: 27701148; PMCID: PMC5096907.
View in: PubMed Mentions: 50 Fields:
Translation:AnimalsCellsPHPublic Health - BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells. Oncotarget. 2016 Jul 26; 7(30):47699-47710. He K, Chen D, Ruan H, Li X, Tong J, Xu X, Zhang L, Yu J. PMID: 27351224; PMCID: PMC5216972.
View in: PubMed Mentions: 41 Fields:
Translation:HumansAnimalsCells - FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation. Oncogene. 2017 02 09; 36(6):787-796. Tong J, Tan S, Zou F, Yu J, Zhang L. PMID: 27399335; PMCID: PMC5226932.
View in: PubMed Mentions: 110 Fields:
Translation:HumansAnimalsCells - Necroptosis: an alternative cell death program defending against cancer. Biochim Biophys Acta. 2016 Apr; 1865(2):228-36. Chen D, Yu J, Zhang L. PMID: 26968619; PMCID: PMC4860077.
View in: PubMed Mentions: 107 Fields:
Translation:Humans - Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers. Nat Commun. 2015 Sep 22; 6:8305. Misale S, Bozic I, Tong J, Peraza-Penton A, Lallo A, Baldi F, Lin KH, Truini M, Trusolino L, Bertotti A, Di Nicolantonio F, Nowak MA, Zhang L, Wood KC, Bardelli A. PMID: 26392303; PMCID: PMC4595628.
View in: PubMed Mentions: 76 Fields:
Translation:HumansAnimalsCells - Amphiphilic sugar poly(orthoesters) as pH-responsive nanoscopic assemblies for acidity-enhanced drug delivery and cell killing. Chem Commun (Camb). 2015 Aug 25; 51(66):13078-81. Li L, Knickelbein K, Zhang L, Wang J, Obrinske M, Ma GZ, Zhang LM, Bitterman L, Du W. PMID: 26096366.
View in: PubMed Mentions: 4 Fields:
Translation:HumansCells - Fibulin-5 inhibits Wnt/β-catenin signaling in lung cancer. Oncotarget. 2015 Jun 20; 6(17):15022-34. Chen X, Song X, Yue W, Chen D, Yu J, Yao Z, Zhang L. PMID: 25909283; PMCID: PMC4558133.
View in: PubMed Mentions: 28 Fields:
Translation:HumansAnimalsCells - Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. Cell Death Dis. 2015 Apr 23; 6:e1729. Brown MF, Leibowitz BJ, Chen D, He K, Zou F, Sobol RW, Beer-Stolz D, Zhang L, Yu J. PMID: 25906152; PMCID: PMC4650537.
View in: PubMed Mentions: 29 Fields:
Translation:HumansCells - mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation. Oncogene. 2016 Jan 14; 35(2):148-57. He K, Zheng X, Li M, Zhang L, Yu J. PMID: 25867072; PMCID: PMC4603992.
View in: PubMed Mentions: 63 Fields:
Translation:HumansAnimalsCells - Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Sci Rep. 2015 Apr 10; 5:8566. Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JCY, Martin MG, Lagasse E, Zhang L, Yu J. PMID: 25858503; PMCID: PMC4392360.
View in: PubMed Mentions: 44 Fields:
Translation:HumansAnimalsCellsPHPublic Health - Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer. Genes Dis. 2015 Mar; 2(1):4-12. Knickelbein K, Zhang L. PMID: 25815366; PMCID: PMC4372129.
View in: PubMed Mentions: 60 - BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16520-5. Leibowitz B, Qiu W, Buchanan ME, Zou F, Vernon P, Moyer MP, Yin XM, Schoen RE, Yu J, Zhang L. PMID: 25368155; PMCID: PMC4246283.
View in: PubMed Mentions: 22 Fields:
Translation:HumansAnimalsCells - Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer. Cell Death Dis. 2014 Oct 30; 5:e1504. Song X, Kim SY, Zhang L, Tang D, Bartlett DL, Kwon YT, Lee YJ. PMID: 25356873; PMCID: PMC4649537.
View in: PubMed Mentions: 34 Fields:
Translation:HumansAnimalsCells - Synthesis of clickable amphiphilic polysaccharides as nanoscopic assemblies. Chem Commun (Camb). 2014 Oct 28; 50(84):12742-5. Fu L, Li L, Wang J, Knickelbein K, Zhang L, Milligan I, Xu Y, O'Hara K, Bitterman L, Du W. PMID: 25204678.
View in: PubMed Mentions: 1 Fields:
Translation:HumansCells - TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity. Oncotarget. 2014 Sep 30; 5(18):8107-22. Chen D, Ming L, Zou F, Peng Y, Van Houten B, Yu J, Zhang L. PMID: 25237903; PMCID: PMC4226670.
View in: PubMed Mentions: 24 Fields:
Translation:HumansAnimalsCells - Receptor interactive protein kinase 3 promotes Cisplatin-triggered necrosis in apoptosis-resistant esophageal squamous cell carcinoma cells. PLoS One. 2014; 9(6):e100127. Xu Y, Lin Z, Zhao N, Zhou L, Liu F, Cichacz Z, Zhang L, Zhan Q, Zhao X. PMID: 24959694; PMCID: PMC4069059.
View in: PubMed Mentions: 25 Fields:
Translation:HumansAnimalsCells - Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis. Clin Cancer Res. 2014 Jul 01; 20(13):3472-84. Chen D, Wei L, Yu J, Zhang L. PMID: 24763611; PMCID: PMC4079733.
View in: PubMed Mentions: 73 Fields:
Translation:HumansAnimalsCells - Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice. Nat Commun. 2014 Mar 18; 5:3494. Leibowitz BJ, Wei L, Zhang L, Ping X, Epperly M, Greenberger J, Cheng T, Yu J. PMID: 24637717; PMCID: PMC4327858.
View in: PubMed Mentions: 55 Fields:
Translation:HumansAnimalsCellsPHPublic Health - Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells. Mol Cancer Ther. 2014 May; 13(5):1298-308. Sun J, Knickelbein K, He K, Chen D, Dudgeon C, Shu Y, Yu J, Zhang L. PMID: 24563542; PMCID: PMC4013266.
View in: PubMed Mentions: 23 Fields:
Translation:HumansAnimalsCells - Role of Bcl-xL/Beclin-1 in interplay between apoptosis and autophagy in oxaliplatin and bortezomib-induced cell death. Biochem Pharmacol. 2014 Mar 15; 88(2):178-88. Kim SY, Song X, Zhang L, Bartlett DL, Lee YJ. PMID: 24486574; PMCID: PMC3969586.
View in: PubMed Mentions: 35 Fields:
Translation:HumansAnimalsCells - Fibulin-3 suppresses Wnt/β-catenin signaling and lung cancer invasion. Carcinogenesis. 2014 Aug; 35(8):1707-16. Chen X, Meng J, Yue W, Yu J, Yang J, Yao Z, Zhang L. PMID: 24480807; PMCID: PMC4123641.
View in: PubMed Mentions: 37 Fields:
Translation:HumansAnimalsCells - Role of apoptosis in colon cancer biology, therapy, and prevention. Curr Colorectal Cancer Rep. 2013 Dec; 9(4). Zhang L, Yu J. PMID: 24273467; PMCID: PMC3836193.
View in: PubMed Mentions: 62 - Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax. Mol Cancer Ther. 2013 Nov; 12(11):2559-68. He K, Zheng X, Zhang L, Yu J. PMID: 23966620; PMCID: PMC3823684.
View in: PubMed Mentions: 27 Fields:
Translation:HumansAnimalsCells - ADAR1 is essential for intestinal homeostasis and stem cell maintenance. Cell Death Dis. 2013 Apr 18; 4:e599. Qiu W, Wang X, Buchanan M, He K, Sharma R, Zhang L, Wang Q, Yu J. PMID: 23598411; PMCID: PMC3641348.
View in: PubMed Mentions: 40 Fields:
Translation:AnimalsCells - PEG-farnesylthiosalicylate conjugate as a nanomicellar carrier for delivery of paclitaxel. Bioconjug Chem. 2013 Mar 20; 24(3):464-72. Zhang X, Lu J, Huang Y, Zhao W, Chen Y, Li J, Gao X, Venkataramanan R, Sun M, Stolz DB, Zhang L, Li S. PMID: 23425093; PMCID: PMC3623935.
View in: PubMed Mentions: 23 Fields:
Translation:HumansAnimalsCells - Crizotinib induces PUMA-dependent apoptosis in colon cancer cells. Mol Cancer Ther. 2013 May; 12(5):777-86. Zheng X, He K, Zhang L, Yu J. PMID: 23427294; PMCID: PMC3651803.
View in: PubMed Mentions: 21 Fields:
Translation:HumansAnimalsCells - Targeting Bax interaction sites reveals that only homo-oligomerization sites are essential for its activation. Cell Death Differ. 2013 May; 20(5):744-54. Peng R, Tong JS, Li H, Yue B, Zou F, Yu J, Zhang L. PMID: 23392123; PMCID: PMC3619242.
View in: PubMed Mentions: 24 Fields:
Translation:HumansCells - The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA. PLoS One. 2012; 7(8):e43158. Sun J, Sun Q, Brown MF, Dudgeon C, Chandler J, Xu X, Shu Y, Zhang L, Yu J. PMID: 22912816; PMCID: PMC3422222.
View in: PubMed Mentions: 26 Fields:
Translation:HumansCells - An apoptosis-independent role of SMAC in tumor suppression. Oncogene. 2013 May 09; 32(19):2380-9. Qiu W, Liu H, Sebastini A, Sun Q, Wang H, Zhang L, Yu J. PMID: 22751125; PMCID: PMC3751796.
View in: PubMed Mentions: 7 Fields:
Translation:HumansAnimalsCells - Investigation of nuclear nano-morphology marker as a biomarker for cancer risk assessment using a mouse model. J Biomed Opt. 2012 Jun; 17(6):066014. Bista RK, Uttam S, Hartman DJ, Qiu W, Yu J, Zhang L, Brand RE, Liu Y. PMID: 22734770; PMCID: PMC3382352.
View in: PubMed Mentions: 5 Fields:
Translation:AnimalsCells - p53/HMGB1 complexes regulate autophagy and apoptosis. Cancer Res. 2012 Apr 15; 72(8):1996-2005. Livesey KM, Kang R, Vernon P, Buchser W, Loughran P, Watkins SC, Zhang L, Manfredi JJ, Zeh HJ, Li L, Lotze MT, Tang D. PMID: 22345153; PMCID: PMC3417120.
View in: PubMed Mentions: 155 Fields:
Translation:HumansAnimalsCells - Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth. Oncogene. 2012 Nov 15; 31(46):4848-58. Dudgeon C, Peng R, Wang P, Sebastiani A, Yu J, Zhang L. PMID: 22286758; PMCID: PMC3342476.
View in: PubMed Mentions: 50 Fields:
Translation:HumansAnimalsCells - Cleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis. Autophagy. 2011 Oct; 7(10):1239-41. Li H, Wang P, Yu J, Zhang L. PMID: 21610315; PMCID: PMC3210308.
View in: PubMed Mentions: 21 Fields:
Translation:HumansCells - PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice. Hepatology. 2011 Oct; 54(4):1249-58. Qiu W, Wang X, Leibowitz B, Yang W, Zhang L, Yu J. PMID: 21725994; PMCID: PMC3184207.
View in: PubMed Mentions: 51 Fields:
Translation:AnimalsCells - Role of Smac in determining the chemotherapeutic response of esophageal squamous cell carcinoma. Clin Cancer Res. 2011 Aug 15; 17(16):5412-22. Xu Y, Zhou L, Huang J, Liu F, Yu J, Zhan Q, Zhang L, Zhao X. PMID: 21676925.
View in: PubMed Mentions: 19 Fields:
Translation:HumansAnimalsCells - p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis. Gastroenterology. 2011 Sep; 141(3):1036-45. Dirisina R, Katzman RB, Goretsky T, Managlia E, Mittal N, Williams DB, Qiu W, Yu J, Chandel NS, Zhang L, Barrett TA. PMID: 21699775; PMCID: PMC3736614.
View in: PubMed Mentions: 50 Fields:
Translation:HumansAnimalsCells - PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. J Clin Invest. 2011 May; 121(5):1722-32. Qiu W, Wu B, Wang X, Buchanan ME, Regueiro MD, Hartman DJ, Schoen RE, Yu J, Zhang L. PMID: 21490394; PMCID: PMC3083802.
View in: PubMed Mentions: 109 Fields:
Translation:HumansAnimalsCells - Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21. Mol Cancer Res. 2011 May; 9(5):616-25. Leibowitz BJ, Qiu W, Liu H, Cheng T, Zhang L, Yu J. PMID: 21450905; PMCID: PMC3096742.
View in: PubMed Mentions: 71 Fields:
Translation:AnimalsCellsPHPublic Health - Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. Cancer Res. 2011 May 15; 71(10):3625-34. Li H, Wang P, Sun Q, Ding WX, Yin XM, Sobol RW, Stolz DB, Yu J, Zhang L. PMID: 21444671; PMCID: PMC3096685.
View in: PubMed Mentions: 85 Fields:
Translation:HumansAnimalsCells - Smac modulates chemosensitivity in head and neck cancer cells through the mitochondrial apoptotic pathway. Clin Cancer Res. 2011 Apr 15; 17(8):2361-72. Sun Q, Zheng X, Zhang L, Yu J. PMID: 21242120; PMCID: PMC3079009.
View in: PubMed Mentions: 12 Fields:
Translation:HumansAnimalsCells - Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death. Curr Top Med Chem. 2011; 11(3):281-90. Mustata G, Li M, Zevola N, Bakan A, Zhang L, Epperly M, Greenberger JS, Yu J, Bahar I. PMID: 21320058; PMCID: PMC3086011.
View in: PubMed Mentions: 29 Fields:
Translation:HumansAnimalsCells - Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):20027-32. Qiu W, Wang X, Leibowitz B, Liu H, Barker N, Okada H, Oue N, Yasui W, Clevers H, Schoen RE, Yu J, Zhang L. PMID: 21041628; PMCID: PMC2993406.
View in: PubMed Mentions: 55 Fields:
Translation:HumansAnimalsCells - Nanoscale nuclear architecture for cancer diagnosis beyond pathology via spatial-domain low-coherence quantitative phase microscopy. J Biomed Opt. 2010 Nov-Dec; 15(6):066028. Wang P, Bista RK, Khalbuss WE, Qiu W, Uttam S, Staton K, Zhang L, Brentnall TA, Brand RE, Liu Y. PMID: 21198202; PMCID: PMC3025597.
View in: PubMed Mentions: 22 Fields:
Translation:HumansAnimalsCells - PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01. Mol Cancer Ther. 2010 Nov; 9(11):2893-902. Dudgeon C, Wang P, Sun X, Peng R, Sun Q, Yu J, Zhang L. PMID: 20978166; PMCID: PMC2978764.
View in: PubMed Mentions: 46 Fields:
Translation:HumansAnimalsCells - An insight into statistical refractive index properties of cell internal structure via low-coherence statistical amplitude microscopy. Opt Express. 2010 Oct 11; 18(21):21950-8. Wang P, Bista RK, Qiu W, Khalbuss WE, Zhang L, Brand RE, Liu Y. PMID: 20941095; PMCID: PMC3408902.
View in: PubMed Mentions: 10 Fields:
Translation:HumansAnimals - Ligand-independent antiapoptotic function of estrogen receptor-beta in lung cancer cells. Mol Endocrinol. 2010 Sep; 24(9):1737-47. Zhang G, Yanamala N, Lathrop KL, Zhang L, Klein-Seetharaman J, Srinivas H. PMID: 20660297; PMCID: PMC2940472.
View in: PubMed Mentions: 39 Fields:
Translation:HumansCells - p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress. J Biol Chem. 2010 Jun 25; 285(26):19910-20. Gurzov EN, Germano CM, Cunha DA, Ortis F, Vanderwinden JM, Marchetti P, Zhang L, Eizirik DL. PMID: 20421300; PMCID: PMC2888402.
View in: PubMed Mentions: 68 Fields:
Translation:HumansAnimalsCells - Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose gamma-irradiation. Blood. 2010 Apr 29; 115(17):3472-80. Yu H, Shen H, Yuan Y, XuFeng R, Hu X, Garrison SP, Zhang L, Yu J, Zambetti GP, Cheng T. PMID: 20177048; PMCID: PMC2867261.
View in: PubMed Mentions: 82 Fields:
Translation:AnimalsCells - Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis. Oncogene. 2010 Mar 18; 29(11):1622-32. Qiu W, Leibowitz B, Zhang L, Yu J. PMID: 19966853; PMCID: PMC3076086.
View in: PubMed Mentions: 81 Fields:
Translation:HumansAnimalsCells - IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells. Cell Death Differ. 2010 Apr; 17(4):699-709. Gao J, Senthil M, Ren B, Yan J, Xing Q, Yu J, Zhang L, Yim JH. PMID: 19851330; PMCID: PMC2838929.
View in: PubMed Mentions: 58 Fields:
Translation:HumansCells - microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer Res. 2009 Oct 15; 69(20):8157-65. Wang P, Zou F, Zhang X, Li H, Dulak A, Tomko RJ, Lazo JS, Wang Z, Zhang L, Yu J. PMID: 19826040; PMCID: PMC2763324.
View in: PubMed Mentions: 167 Fields:
Translation:Humans - Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21. Cell Cycle. 2009 Oct 01; 8(19):3157-64. de Oliveira PE, Zhang L, Wang Z, Lazo JS. PMID: 19738433.
View in: PubMed Mentions: 24 Fields:
Translation:HumansCells - Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression. Cancer Res. 2009 Aug 01; 69(15):6339-46. Yue W, Sun Q, Landreneau R, Wu C, Siegfried JM, Yu J, Zhang L. PMID: 19584278; PMCID: PMC2719681.
View in: PubMed Mentions: 57 Fields:
Translation:HumansAnimalsCells - PUMA suppresses intestinal tumorigenesis in mice. Cancer Res. 2009 Jun 15; 69(12):4999-5006. Qiu W, Carson-Walter EB, Kuan SF, Zhang L, Yu J. PMID: 19491259; PMCID: PMC2872079.
View in: PubMed Mentions: 34 Fields:
Translation:Animals - PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis. Cell Death Differ. 2009 Sep; 16(9):1192-202. Wang P, Qiu W, Dudgeon C, Liu H, Huang C, Zambetti GP, Yu J, Zhang L. PMID: 19444283; PMCID: PMC2872087.
View in: PubMed Mentions: 112 Fields:
Translation:HumansAnimalsCells - PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells. Oncogene. 2009 Jun 18; 28(24):2348-57. Sun Q, Ming L, Thomas SM, Wang Y, Chen ZG, Ferris RL, Grandis JR, Zhang L, Yu J. PMID: 19421143; PMCID: PMC2872091.
View in: PubMed Mentions: 44 Fields:
Translation:HumansAnimalsCells - PUMA, a potent killer with or without p53. Oncogene. 2008 Dec; 27 Suppl 1:S71-83. Yu J, Zhang L. PMID: 19641508; PMCID: PMC2860432.
View in: PubMed Mentions: 289 Fields:
Translation:HumansAnimalsCells - Sp1 and p73 activate PUMA following serum starvation. Carcinogenesis. 2008 Oct; 29(10):1878-84. Ming L, Sakaida T, Yue W, Jha A, Zhang L, Yu J. PMID: 18579560; PMCID: PMC2722853.
View in: PubMed Mentions: 57 Fields:
Translation:HumansCells - Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis. Mol Cell Biol. 2008 Sep; 28(17):5391-402. Garrison SP, Jeffers JR, Yang C, Nilsson JA, Hall MA, Rehg JE, Yue W, Yu J, Zhang L, Onciu M, Sample JT, Cleveland JL, Zambetti GP. PMID: 18573879; PMCID: PMC2519737.
View in: PubMed Mentions: 84 Fields:
Translation:HumansAnimalsCells - PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome. Cell Stem Cell. 2008 Jun 05; 2(6):576-83. Qiu W, Carson-Walter EB, Liu H, Epperly M, Greenberger JS, Zambetti GP, Zhang L, Yu J. PMID: 18522850; PMCID: PMC2892934.
View in: PubMed Mentions: 121 Fields:
Translation:AnimalsCellsPHPublic Health - Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. Biochem Pharmacol. 2008 May 15; 75(10):2020-33. Lee DH, Kim C, Zhang L, Lee YJ. PMID: 18377871; PMCID: PMC2424318.
View in: PubMed Mentions: 49 Fields:
Translation:HumansCells - Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway. J Biol Chem. 2008 Mar 28; 283(13):8624-33. Luo W, Liu J, Li J, Zhang D, Liu M, Addo JK, Patil S, Zhang L, Yu J, Buolamwini JK, Chen J, Huang C. PMID: 18218619; PMCID: PMC2417161.
View in: PubMed Mentions: 20 Fields:
Translation:HumansAnimalsCells - NSAIDs downregulate Bcl-X(L) and dissociate BAX and Bcl-X(L) to induce apoptosis in colon cancer cells. Nutr Cancer. 2008; 60 Suppl 1:98-103. Bank A, Yu J, Zhang L. PMID: 19003586.
View in: PubMed Mentions: 11 Fields:
Translation:HumansCells - SMAC mimetics sensitize nonsteroidal anti-inflammatory drug-induced apoptosis by promoting caspase-3-mediated cytochrome c release. Cancer Res. 2008 Jan 01; 68(1):276-84. Bank A, Wang P, Du C, Yu J, Zhang L. PMID: 18172320.
View in: PubMed Mentions: 15 Fields:
Translation:HumansCells - PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells. J Biol Chem. 2008 Feb 01; 283(5):2508-17. Chen K, Tu Y, Zhang Y, Blair HC, Zhang L, Wu C. PMID: 18063582.
View in: PubMed Mentions: 46 Fields:
Translation:HumansCells - Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer. Carcinogenesis. 2008 Jan; 29(1):84-92. Yue W, Sun Q, Dacic S, Landreneau RJ, Siegfried JM, Yu J, Zhang L. PMID: 18048388.
View in: PubMed Mentions: 80 Fields:
Translation:HumansCells - BH3 mimetics to improve cancer therapy; mechanisms and examples. Drug Resist Updat. 2007 Dec; 10(6):207-17. Zhang L, Ming L, Yu J. PMID: 17921043; PMCID: PMC2265791.
View in: PubMed Mentions: 56 Fields:
Translation:HumansAnimalsCells - Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation. Clin Cancer Res. 2007 Aug 01; 13(15 Pt 1):4336-44. Yue W, Dacic S, Sun Q, Landreneau R, Guo M, Zhou W, Siegfried JM, Yu J, Zhang L. PMID: 17671114.
View in: PubMed Mentions: 42 Fields:
Translation:HumansCells - A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells. Mol Cancer Ther. 2007 Mar; 6(3):1062-9. Ding WX, Ni HM, Chen X, Yu J, Zhang L, Yin XM. PMID: 17363499.
View in: PubMed Mentions: 34 Fields:
Translation:HumansAnimalsCells - The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):4054-9. Wang P, Yu J, Zhang L. PMID: 17360476; PMCID: PMC1820707.
View in: PubMed Mentions: 93 Fields:
Translation:HumansCells - SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events. Oncogene. 2007 Jun 21; 26(29):4189-98. Yu J, Wang P, Ming L, Wood MA, Zhang L. PMID: 17237824.
View in: PubMed Mentions: 55 Fields:
Translation:HumansCells - p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion. Gut. 2007 May; 56(5):645-54. Wu B, Qiu W, Wang P, Yu H, Cheng T, Zambetti GP, Zhang L, Yu J. PMID: 17127703; PMCID: PMC1942137.
View in: PubMed Mentions: 70 Fields:
Translation:Animals - PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation. Clin Cancer Res. 2006 May 01; 12(9):2928-36. Yu J, Yue W, Wu B, Zhang L. PMID: 16675590.
View in: PubMed Mentions: 47 Fields:
Translation:HumansAnimalsCells - PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells. J Biol Chem. 2006 Jun 09; 281(23):16034-42. Ming L, Wang P, Bank A, Yu J, Zhang L. PMID: 16608847.
View in: PubMed Mentions: 97 Fields:
Translation:HumansCells - Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs. Cancer Biol Ther. 2006 Apr; 5(4):380-5. Wang H, Qian H, Yu J, Zhang X, Zhang L, Fu M, Liang X, Zhan Q, Lin C. PMID: 16481741.
View in: PubMed Mentions: 18 Fields:
Translation:HumansCells - Regulation of PUMA-alpha by p53 in cisplatin-induced renal cell apoptosis. Oncogene. 2006 Jul 06; 25(29):4056-66. Jiang M, Wei Q, Wang J, Du Q, Yu J, Zhang L, Dong Z. PMID: 16491117.
View in: PubMed Mentions: 111 Fields:
Translation:HumansAnimalsCells - The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun. 2005 Jun 10; 331(3):851-8. Yu J, Zhang L. PMID: 15865941.
View in: PubMed Mentions: 144 Fields:
Translation:HumansAnimalsCells - SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells. Proc Natl Acad Sci U S A. 2004 Nov 30; 101(48):16897-902. Kohli M, Yu J, Seaman C, Bardelli A, Kinzler KW, Vogelstein B, Lengauer C, Zhang L. PMID: 15557007; PMCID: PMC534714.
View in: PubMed Mentions: 30 Fields:
Translation:HumansCells - Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C. J Biol Chem. 2004 Jun 11; 279(24):25813-22. Singh SV, Herman-Antosiewicz A, Singh AV, Lew KL, Srivastava SK, Kamath R, Brown KD, Zhang L, Baskaran R. PMID: 15073169.
View in: PubMed Mentions: 112 Fields:
Translation:HumansCells - Apoptosis in human cancer cells. Curr Opin Oncol. 2004 Jan; 16(1):19-24. Yu J, Zhang L. PMID: 14685088.
View in: PubMed Mentions: 42 Fields:
Translation:HumansCells - Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells. Cancer Biol Ther. 2003 Nov-Dec; 2(6):694-9. Yu J, Tiwari S, Steiner P, Zhang L. PMID: 14688479.
View in: PubMed Mentions: 28 Fields:
Translation:HumansCells - No PUMA, no death: implications for p53-dependent apoptosis. Cancer Cell. 2003 Oct; 4(4):248-9. Yu J, Zhang L. PMID: 14585351.
View in: PubMed Mentions: 80 Fields:
Translation:AnimalsCells - Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Res. 2003 Mar 01; 63(5):994-9. Hempen PM, Zhang L, Bansal RK, Iacobuzio-Donahue CA, Murphy KM, Maitra A, Vogelstein B, Whitehead RH, Markowitz SD, Willson JK, Yeo CJ, Hruban RH, Kern SE. PMID: 12615714.
View in: PubMed Mentions: 59 Fields:
Translation:HumansCells - PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1931-6. Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L. PMID: 12574499; PMCID: PMC149936.
View in: PubMed Mentions: 256 Fields:
Translation:HumansCells - Screening poly [dA/dT(-)] cDNA for gene identification. Methods Mol Biol. 2003; 221:197-205. Wang SM, Fears SC, Zhang L, Chen JJ, Rowley JD. PMID: 12703745.
View in: PubMed Mentions: Fields:
Translation:Humans - Single-sperm typing. Curr Protoc Hum Genet. 2002 May; Chapter 1:Unit 1.6. Lien S, Szyda J, Leeflang EP, Hubert R, Zhang L, Schmitt K, Arnheim N. PMID: 18428321.
View in: PubMed Mentions: 3 Fields:
Translation:HumansCells - Secreted and cell surface genes expressed in benign and malignant colorectal tumors. Cancer Res. 2001 Oct 01; 61(19):6996-7001. Buckhaults P, Rago C, St Croix B, Romans KE, Saha S, Zhang L, Vogelstein B, Kinzler KW. PMID: 11585723.
View in: PubMed Mentions: 83 Fields:
Translation:Humans - Serial analysis of gene expression in the frontal cortex of patients with bipolar disorder. Br J Psychiatry Suppl. 2001 Jun; 41:s137-41. Sun Y, Zhang L, Johnston NL, Torrey EF, Yolken RH. PMID: 11450174.
View in: PubMed Mentions: 16 Fields:
Translation:HumansCells - Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers. Cancer Res. 2001 May 01; 61(9):3801-5. Zhang L, Yu J, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. PMID: 11325855.
View in: PubMed Mentions: 15 Fields:
Translation:HumansAnimalsCells - PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell. 2001 Mar; 7(3):673-82. Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B. PMID: 11463391.
View in: PubMed Mentions: 517 Fields:
Translation:HumansAnimalsCells - Role of BAX in the apoptotic response to anticancer agents. Science. 2000 Nov 03; 290(5493):989-92. Zhang L, Yu J, Park BH, Kinzler KW, Vogelstein B. PMID: 11062132.
View in: PubMed Mentions: 286 Fields:
Translation:HumansCells - The mRNA of L-type calcium channel elevated in colon cancer: protein distribution in normal and cancerous colon. Am J Pathol. 2000 Nov; 157(5):1549-62. Wang XT, Nagaba Y, Cross HS, Wrba F, Zhang L, Guggino SE. PMID: 11073814; PMCID: PMC1885745.
View in: PubMed Mentions: 41 Fields:
Translation:HumansCells - Screening poly(dA/dT)- cDNAs for gene identification. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4162-7. Wang SM, Fears SC, Zhang L, Chen JJ, Rowley JD. PMID: 10760283; PMCID: PMC18183.
View in: PubMed Mentions: 14 Fields:
Translation:HumansCells - Identification and classification of p53-regulated genes. Proc Natl Acad Sci U S A. 1999 Dec 07; 96(25):14517-22. Yu J, Zhang L, Hwang PM, Rago C, Kinzler KW, Vogelstein B. PMID: 10588737; PMCID: PMC24468.
View in: PubMed Mentions: 122 Fields:
Translation:HumansCells - Analysis of human transcriptomes. Nat Genet. 1999 Dec; 23(4):387-8. Velculescu VE, Madden SL, Zhang L, Lash AE, Yu J, Rago C, Lal A, Wang CJ, Beaudry GA, Ciriello KM, Cook BP, Dufault MR, Ferguson AT, Gao Y, He TC, Hermeking H, Hiraldo SK, Hwang PM, Lopez MA, Luderer HF, Mathews B, Petroziello JM, Polyak K, Zawel L, Kinzler KW, et al. PMID: 10581018.
View in: PubMed Mentions: 241 Fields:
Translation:HumansCells - A public database for gene expression in human cancers. Cancer Res. 1999 Nov 01; 59(21):5403-7. Lal A, Lash AE, Altschul SF, Velculescu V, Zhang L, McLendon RE, Marra MA, Prange C, Morin PJ, Polyak K, Papadopoulos N, Vogelstein B, Kinzler KW, Strausberg RL, Riggins GJ. PMID: 10554005.
View in: PubMed Mentions: 116 Fields:
Translation:Humans - The mutation properties of spinal and bulbar muscular atrophy disease alleles. Neurogenetics. 1998 Aug; 1(4):249-52. Grewal RP, Leeflang EP, Zhang L, Arnheim N. PMID: 10732798.
View in: PubMed Mentions: 1 Fields:
Translation:HumansCells - Identifying markers for pancreatic cancer by gene expression analysis. Cancer Epidemiol Biomarkers Prev. 1998 Feb; 7(2):109-12. Zhou W, Sokoll LJ, Bruzek DJ, Zhang L, Velculescu VE, Goldin SB, Hruban RH, Kern SE, Hamilton SR, Chan DW, Vogelstein B, Kinzler KW. PMID: 9488584.
View in: PubMed Mentions: 33 Fields:
Translation:Humans - 14-3-3sigma is a p53-regulated inhibitor of G2/M progression. Mol Cell. 1997 Dec; 1(1):3-11. Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B. PMID: 9659898.
View in: PubMed Mentions: 369 Fields:
Translation:HumansCells - Gene expression profiles in normal and cancer cells. Science. 1997 May 23; 276(5316):1268-72. Zhang L, Zhou W, Velculescu VE, Kern SE, Hruban RH, Hamilton SR, Vogelstein B, Kinzler KW. PMID: 9157888.
View in: PubMed Mentions: 363 Fields:
Translation:HumansCells - Characterization of the yeast transcriptome. Cell. 1997 Jan 24; 88(2):243-51. Velculescu VE, Zhang L, Zhou W, Vogelstein J, Basrai MA, Bassett DE, Hieter P, Vogelstein B, Kinzler KW. PMID: 9008165.
View in: PubMed Mentions: 307 Fields:
Translation:AnimalsCells - Serial analysis of gene expression. Science. 1995 Oct 20; 270(5235):484-7. Velculescu VE, Zhang L, Vogelstein B, Kinzler KW. PMID: 7570003.
View in: PubMed Mentions: 961 Fields:
Translation:HumansCells - Single sperm analysis of the trinucleotide repeats in the Huntington's disease gene: quantification of the mutation frequency spectrum. Hum Mol Genet. 1995 Sep; 4(9):1519-26. Leeflang EP, Zhang L, Tavaré S, Hubert R, Srinidhi J, MacDonald ME, Myers RH, de Young M, Wexler NS, Gusella JF, et al. PMID: 8541834.
View in: PubMed Mentions: 45 Fields:
Translation:HumansCells - Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell. 1995 Jul 28; 82(2):309-19. Baker SM, Bronner CE, Zhang L, Plug AW, Robatzek M, Warren G, Elliott EA, Yu J, Ashley T, Arnheim N, Flavell RA, Liskay RM. PMID: 7628019.
View in: PubMed Mentions: 145 Fields:
Translation:HumansAnimalsCells - CAG repeat length variation in sperm from a patient with Kennedy's disease. Hum Mol Genet. 1995 Feb; 4(2):303-5. Zhang L, Fischbeck KH, Arnheim N. PMID: 7757084.
View in: PubMed Mentions: 9 Fields:
Translation:HumansCells - Studying human mutations by sperm typing: instability of CAG trinucleotide repeats in the human androgen receptor gene. Nat Genet. 1994 Aug; 7(4):531-5. Zhang L, Leeflang EP, Yu J, Arnheim N. PMID: 7951325.
View in: PubMed Mentions: 26 Fields:
Translation:HumansCells - A new source of polymorphic DNA markers for sperm typing: analysis of microsatellite repeats in single cells. Am J Hum Genet. 1992 Nov; 51(5):985-91. Hubert R, Weber JL, Schmitt K, Zhang L, Arnheim N. PMID: 1415267; PMCID: PMC1682826.
View in: PubMed Mentions: 7 Fields:
Translation:HumansCells - Whole genome amplification from a single cell: implications for genetic analysis. Proc Natl Acad Sci U S A. 1992 Jul 01; 89(13):5847-51. Zhang L, Cui X, Schmitt K, Hubert R, Navidi W, Arnheim N. PMID: 1631067; PMCID: PMC49394.
View in: PubMed Mentions: 263 Fields:
Translation:HumansCells
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