Gabriel Travis • UCLA Profiles (original) (raw)
- Germline Disruption of Retinal Pigment Epithelium-Expressed Zebrafish rlbp1b-/- Results in Selective Dim Light Visual Behavior Deficits and Provides a Screening Platform for Evaluating the Pathogenicity of Human RLBP1 Variants. FASEB J. 2025 Jun 30; 39(12):e70754. Fehilly JD, McCann T, Ruddin G, Kaylor JJ, Grenville H, Ward R, Wynne K, Sánchez AG, Strachan E, Travis GH, Collery RF, Kennedy BN. PMID: 40552921; PMCID: PMC12186719.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimals - RDH12 allows cone photoreceptors to regenerate opsin visual pigments from a chromophore precursor to escape competition with rods. Curr Biol. 2024 Aug 05; 34(15):3342-3353.e6. Kaylor JJ, Frederiksen R, Bedrosian CK, Huang M, Stennis-Weatherspoon D, Huynh T, Ngan T, Mulamreddy V, Sampath AP, Fain GL, Travis GH. PMID: 38981477; PMCID: PMC11303097.
View in: PubMed Mentions: 3 Fields:
Translation:HumansAnimalsCells - Dawn and dusk peaks of outer segment phagocytosis, and visual cycle function require Rab28. FASEB J. 2022 05; 36(5):e22309. Moran AL, Carter SP, Kaylor JJ, Jiang Z, Broekman S, Dillon ET, Gómez Sánchez A, Minhas SK, van Wijk E, Radu RA, Travis GH, Carey M, Blacque OE, Kennedy BN. PMID: 35471581; PMCID: PMC9322422.
View in: PubMed Mentions: 8 Fields:
Translation:HumansAnimalsCells - Rod Photoreceptors Avoid Saturation in Bright Light by the Movement of the G Protein Transducin. J Neurosci. 2021 04 14; 41(15):3320-3330. Frederiksen R, Morshedian A, Tripathy SA, Xu T, Travis GH, Fain GL, Sampath AP. PMID: 33593858; PMCID: PMC8051685.
View in: PubMed Mentions: 25 Fields:
Translation:AnimalsCells - Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision. J Biol Chem. 2020 05 08; 295(19):6482-6497. Ward R, Kaylor JJ, Cobice DF, Pepe DA, McGarrigle EM, Brockerhoff SE, Hurley JB, Travis GH, Kennedy BN. PMID: 32238432; PMCID: PMC7212626.
View in: PubMed Mentions: 15 Fields:
Translation:AnimalsCells - Light-Driven Regeneration of Cone Visual Pigments through a Mechanism Involving RGR Opsin in Müller Glial Cells. Neuron. 2019 06 19; 102(6):1172-1183.e5. Morshedian A, Kaylor JJ, Ng SY, Tsan A, Frederiksen R, Xu T, Yuan L, Sampath AP, Radu RA, Fain GL, Travis GH. PMID: 31056353; PMCID: PMC6586478.
View in: PubMed Mentions: 70 Fields:
Translation:AnimalsCells - Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):E11120-E11127. Lenis TL, Hu J, Ng SY, Jiang Z, Sarfare S, Lloyd MB, Esposito NJ, Samuel W, Jaworski C, Bok D, Finnemann SC, Radeke MJ, Redmond TM, Travis GH, Radu RA. PMID: 30397118; PMCID: PMC6255167.
View in: PubMed Mentions: 95 Fields:
Translation:AnimalsCells - Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium. J Biol Chem. 2017 12 29; 292(52):21407-21416. Cook JD, Ng SY, Lloyd M, Eddington S, Sun H, Nathans J, Bok D, Radu RA, Travis GH. PMID: 29109151; PMCID: PMC5766940.
View in: PubMed Mentions: 13 Fields:
Translation:AnimalsCells - Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. Nat Commun. 2017 05 04; 8(1):16. Kaylor JJ, Xu T, Ingram NT, Tsan A, Hakobyan H, Fain GL, Travis GH. PMID: 28473692; PMCID: PMC5432035.
View in: PubMed Mentions: 34 Fields:
Translation:AnimalsCells - Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epithelium. PLoS One. 2015; 10(5):e0125921. Kaylor JJ, Radu RA, Bischoff N, Makshanoff J, Hu J, Lloyd M, Eddington S, Bianconi T, Bok D, Travis GH. PMID: 25974161; PMCID: PMC4431840.
View in: PubMed Mentions: 9 Fields:
Translation:AnimalsCells - Identification of the 11-cis-specific retinyl-ester synthase in retinal Müller cells as multifunctional O-acyltransferase (MFAT). Proc Natl Acad Sci U S A. 2014 May 20; 111(20):7302-7. Kaylor JJ, Cook JD, Makshanoff J, Bischoff N, Yong J, Travis GH. PMID: 24799687; PMCID: PMC4034218.
View in: PubMed Mentions: 30 Fields:
Translation:HumansAnimalsCells - Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein. J Neurosci. 2013 Oct 30; 33(44):17458-68. Sato K, Li S, Gordon WC, He J, Liou GI, Hill JM, Travis GH, Bazan NG, Jin M. PMID: 24174679; PMCID: PMC3812510.
View in: PubMed Mentions: 62 Fields:
Translation:AnimalsCells - Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina. Nat Chem Biol. 2013 Jan; 9(1):30-6. Kaylor JJ, Yuan Q, Cook J, Sarfare S, Makshanoff J, Miu A, Kim A, Kim P, Habib S, Roybal CN, Xu T, Nusinowitz S, Travis GH. PMID: 23143414; PMCID: PMC3522777.
View in: PubMed Mentions: 63 Fields:
Translation:AnimalsCells - Autosomal recessive retinitis pigmentosa due to ABCA4 mutations: clinical, pathologic, and molecular characterization. Invest Ophthalmol Vis Sci. 2012 Apr 18; 53(4):1883-94. Mullins RF, Kuehn MH, Radu RA, Enriquez GS, East JS, Schindler EI, Travis GH, Stone EM. PMID: 22395892; PMCID: PMC3995570.
View in: PubMed Mentions: 39 Fields:
Translation:HumansCells - Receptor-mediated cellular uptake mechanism that couples to intracellular storage. ACS Chem Biol. 2011 Oct 21; 6(10):1041-51. Kawaguchi R, Yu J, Ter-Stepanian M, Zhong M, Cheng G, Yuan Q, Jin M, Travis GH, Ong D, Sun H. PMID: 21774515; PMCID: PMC3199320.
View in: PubMed Mentions: 53 Fields:
Translation:HumansAnimalsCells - Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylation. Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3483-91. Blakeley LR, Chen C, Chen CK, Chen J, Crouch RK, Travis GH, Koutalos Y. PMID: 21398289; PMCID: PMC3109038.
View in: PubMed Mentions: 17 Fields:
Translation:AnimalsCells - Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration. J Biol Chem. 2011 May 27; 286(21):18593-601. Radu RA, Hu J, Yuan Q, Welch DL, Makshanoff J, Lloyd M, McMullen S, Travis GH, Bok D. PMID: 21464132; PMCID: PMC3099675.
View in: PubMed Mentions: 93 Fields:
Translation:HumansAnimalsCells - Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells. Hum Mol Genet. 2010 Nov 01; 19(21):4229-38. Liao JL, Yu J, Huang K, Hu J, Diemer T, Ma Z, Dvash T, Yang XJ, Travis GH, Williams DS, Bok D, Fan G. PMID: 20709808; PMCID: PMC3115666.
View in: PubMed Mentions: 102 Fields:
Translation:HumansCells - Flow of energy in the outer retina in darkness and in light. Proc Natl Acad Sci U S A. 2010 May 11; 107(19):8599-604. Linton JD, Holzhausen LC, Babai N, Song H, Miyagishima KJ, Stearns GW, Lindsay K, Wei J, Chertov AO, Peters TA, Caffe R, Pluk H, Seeliger MW, Tanimoto N, Fong K, Bolton L, Kuok DL, Sweet IR, Bartoletti TM, Radu RA, Travis GH, Zagotta WN, Townes-Anderson E, Parker E, Van der Zee CE, Sampath AP, Sokolov M, Thoreson WB, Hurley JB. PMID: 20445106; PMCID: PMC2889335.
View in: PubMed Mentions: 77 Fields:
Translation:AnimalsCells - Analysis of the retinoid isomerase activities in the retinal pigment epithelium and retina. Methods Mol Biol. 2010; 652:329-39. Travis GH, Kaylor J, Yuan Q. PMID: 20552438; PMCID: PMC3049333.
View in: PubMed Mentions: 5 Fields:
Translation:Animals - Rpe65 isomerase associates with membranes through an electrostatic interaction with acidic phospholipid headgroups. J Biol Chem. 2010 Jan 08; 285(2):988-99. Yuan Q, Kaylor JJ, Miu A, Bassilian S, Whitelegge JP, Travis GH. PMID: 19892706; PMCID: PMC2801300.
View in: PubMed Mentions: 8 Fields:
Translation:AnimalsCells - Predicting the pathogenicity of RPE65 mutations. Hum Mutat. 2009 Aug; 30(8):1183-8. Philp AR, Jin M, Li S, Schindler EI, Iannaccone A, Lam BL, Weleber RG, Fishman GA, Jacobson SG, Mullins RF, Travis GH, Stone EM. PMID: 19431183; PMCID: PMC2717180.
View in: PubMed Mentions: 29 Fields:
Translation:HumansCells - The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors. J Neurosci. 2009 Feb 04; 29(5):1486-95. Jin M, Li S, Nusinowitz S, Lloyd M, Hu J, Radu RA, Bok D, Travis GH. PMID: 19193895; PMCID: PMC2680234.
View in: PubMed Mentions: 69 Fields:
Translation:HumansAnimalsCells - Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation. Invest Ophthalmol Vis Sci. 2008 Sep; 49(9):3821-9. Radu RA, Yuan Q, Hu J, Peng JH, Lloyd M, Nusinowitz S, Bok D, Travis GH. PMID: 18515570; PMCID: PMC2851626.
View in: PubMed Mentions: 97 Fields:
Translation:Animals - Retinal pigment epithelium-retinal G protein receptor-opsin mediates light-dependent translocation of all-trans-retinyl esters for synthesis of visual chromophore in retinal pigment epithelial cells. J Biol Chem. 2008 Jul 11; 283(28):19730-8. Radu RA, Hu J, Peng J, Bok D, Mata NL, Travis GH. PMID: 18474598; PMCID: PMC2443657.
View in: PubMed Mentions: 57 Fields:
Translation:HumansAnimalsCells - A novel form of transducin-dependent retinal degeneration: accelerated retinal degeneration in the absence of rod transducin. Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5445-53. Brill E, Malanson KM, Radu RA, Boukharov NV, Wang Z, Chung HY, Lloyd MB, Bok D, Travis GH, Obin M, Lem J. PMID: 18055791; PMCID: PMC2248236.
View in: PubMed Mentions: 12 Fields:
Translation:AnimalsCells - Role of LRAT on the retinoid isomerase activity and membrane association of Rpe65. J Biol Chem. 2007 Jul 20; 282(29):20915-24. Jin M, Yuan Q, Li S, Travis GH. PMID: 17504753; PMCID: PMC2747659.
View in: PubMed Mentions: 34 Fields:
Translation:HumansAnimalsCells - Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents. Annu Rev Pharmacol Toxicol. 2007; 47:469-512. Travis GH, Golczak M, Moise AR, Palczewski K. PMID: 16968212; PMCID: PMC2442882.
View in: PubMed Mentions: 260 Fields:
Translation:HumansAnimalsCells - Characterization of native retinal fluorophores involved in biosynthesis of A2E and lipofuscin-associated retinopathies. J Biol Chem. 2006 Jun 30; 281(26):18112-9. Bui TV, Han Y, Radu RA, Travis GH, Mata NL. PMID: 16638746.
View in: PubMed Mentions: 18 Fields:
Translation:AnimalsCells - Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases. Invest Ophthalmol Vis Sci. 2005 Dec; 46(12):4393-401. Radu RA, Han Y, Bui TV, Nusinowitz S, Bok D, Lichter J, Widder K, Travis GH, Mata NL. PMID: 16303925.
View in: PubMed Mentions: 110 Fields:
Translation:Animals - Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol. Biochemistry. 2005 Sep 06; 44(35):11715-21. Mata NL, Ruiz A, Radu RA, Bui TV, Travis GH. PMID: 16128572; PMCID: PMC2851629.
View in: PubMed Mentions: 53 Fields:
Translation:AnimalsCells - Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium. Cell. 2005 Aug 12; 122(3):449-59. Jin M, Li S, Moghrabi WN, Sun H, Travis GH. PMID: 16096063; PMCID: PMC2748856.
View in: PubMed Mentions: 248 Fields:
Translation:HumansAnimalsCells - Acyl CoA:retinol acyltransferase (ARAT) activity is present in bovine retinal pigment epithelium. Exp Eye Res. 2006 Jan; 82(1):111-21. Kaschula CH, Jin MH, Desmond-Smith NS, Travis GH. PMID: 16054134.
View in: PubMed Mentions: 18 Fields:
Translation:HumansAnimalsCells - DISCO! Dissociation of cone opsins: the fast and noisy life of cones explained. Neuron. 2005 Jun 16; 46(6):840-2. Travis GH. PMID: 15953411.
View in: PubMed Mentions: 2 Fields:
Translation:AnimalsCells - Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration. Proc Natl Acad Sci U S A. 2004 Apr 20; 101(16):5928-33. Radu RA, Mata NL, Bagla A, Travis GH. PMID: 15067110; PMCID: PMC395900.
View in: PubMed Mentions: 83 Fields:
Translation:Animals - Isotretinoin treatment inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration. Novartis Found Symp. 2004; 255:51-63; discussion 63-7, 177-8. Radu RA, Mata NL, Nusinowitz S, Liu X, Travis GH. PMID: 14750596.
View in: PubMed Mentions: 12 Fields:
Translation:Animals - Rpe65 is a retinyl ester binding protein that presents insoluble substrate to the isomerase in retinal pigment epithelial cells. J Biol Chem. 2004 Jan 02; 279(1):635-43. Mata NL, Moghrabi WN, Lee JS, Bui TV, Radu RA, Horwitz J, Travis GH. PMID: 14532273.
View in: PubMed Mentions: 53 Fields:
Translation:AnimalsCells - Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4742-7. Radu RA, Mata NL, Nusinowitz S, Liu X, Sieving PA, Travis GH. PMID: 12671074; PMCID: PMC153626.
View in: PubMed Mentions: 109 Fields:
Translation:HumansAnimalsCells - Isomerization and oxidation of vitamin a in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight. Neuron. 2002 Sep 26; 36(1):69-80. Mata NL, Radu RA, Clemmons RC, Travis GH. PMID: 12367507; PMCID: PMC2851622.
View in: PubMed Mentions: 185 Fields:
Translation:AnimalsCells
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
Start with: newest oldestInclude: line numbers double spacing all authors publication IDs