Luis De La Torre-Ubieta • UCLA Profiles (original) (raw)

  1. Development of Molecular Neuropathology in Down Syndrome across the Lifespan. J Neurosci. 2025 11 12; 45(46). Bhattacharyya A, de la Torre-Ubieta L, Zhu Y, Head E, Swarup V, Sousa AMM. PMID: 41224669; PMCID: PMC12614066.
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  2. Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis. Am J Hum Genet. 2024 Sep 05; 111(9):1877-1898. Aygün N, Vuong C, Krupa O, Mory J, Le BD, Valone JM, Liang D, Shafie B, Zhang P, Salinda A, Wen C, Gandal MJ, Love MI, de la Torre-Ubieta L, Stein JL. PMID: 39168119; PMCID: PMC11393701.
    View in: PubMed Mentions: 2 Fields:
    Translation:HumansCells
  3. Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms. Science. 2024 05 24; 384(6698):eadh7688. Patowary A, Zhang P, Jops C, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, de la Torre-Ubieta L. PMID: 38781356; PMCID: PMC11960787.
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    Translation:HumansCells
  4. Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms. bioRxiv. 2023 Oct 11. Patowary A, Zhang P, Jops C, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, de la Torre-Ubieta L. PMID: 36993726; PMCID: PMC10055310.
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  5. MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size. Elife. 2023 01 11; 12. Lafferty MJ, Aygün N, Patel NK, Krupa O, Liang D, Wolter JM, Geschwind DH, de la Torre-Ubieta L, Stein JL. PMID: 36629315; PMCID: PMC9859047.
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    Translation:Humans
  6. TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. Stem Cell Reports. 2022 10 11; 17(10):2220-2238. Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG. PMID: 36179695; PMCID: PMC9561534.
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    Translation:HumansCells
  7. Defining the evolutionary and gene regulatory logic of vertebrate neuronal diversity. Neuron. 2022 01 05; 110(1):3-5. de la Torre-Ubieta L. PMID: 34990577.
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    Translation:AnimalsCells
  8. Brain-trait-associated variants impact cell-type-specific gene regulation during neurogenesis. Am J Hum Genet. 2021 09 02; 108(9):1647-1668. Aygün N, Elwell AL, Liang D, Lafferty MJ, Cheek KE, Courtney KP, Mory J, Hadden-Ford E, Krupa O, de la Torre-Ubieta L, Geschwind DH, Love MI, Stein JL. PMID: 34416157; PMCID: PMC8456186.
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    Translation:HumansCells
  9. Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation. Nat Neurosci. 2021 07; 24(7):941-953. Liang D, Elwell AL, Aygün N, Krupa O, Wolter JM, Kyere FA, Lafferty MJ, Cheek KE, Courtney KP, Yusupova M, Garrett ME, Ashley-Koch A, Crawford GE, Love MI, de la Torre-Ubieta L, Geschwind DH, Stein JL. PMID: 34017130; PMCID: PMC8254789.
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    Translation:HumansCells
  10. Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia. Nat Neurosci. 2021 06; 24(6):799-809. Kim M, Haney JR, Zhang P, Hernandez LM, Wang LK, Perez-Cano L, Loohuis LMO, de la Torre-Ubieta L, Gandal MJ. PMID: 33958802; PMCID: PMC8178202.
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    Translation:HumansCells
  11. Author Correction: Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders. Nat Commun. 2020 Nov 17; 11(1):5936. Seidlitz J, Nadig A, Liu S, Bethlehem RAI, Vértes PE, Morgan SE, Váša F, Romero-Garcia R, Lalonde FM, Clasen LS, Blumenthal JD, Paquola C, Bernhardt B, Wagstyl K, Polioudakis D, de la Torre-Ubieta L, Geschwind DH, Han JC, Lee NR, Murphy DG, Bullmore ET, Raznahan A. PMID: 33203864; PMCID: PMC7672093.
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  12. Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders. Nat Commun. 2020 07 03; 11(1):3358. Seidlitz J, Nadig A, Liu S, Bethlehem RAI, Vértes PE, Morgan SE, Váša F, Romero-Garcia R, Lalonde FM, Clasen LS, Blumenthal JD, Paquola C, Bernhardt B, Wagstyl K, Polioudakis D, de la Torre-Ubieta L, Geschwind DH, Han JC, Lee NR, Murphy DG, Bullmore ET, Raznahan A. PMID: 32620757; PMCID: PMC7335069.
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    Translation:HumansCells
  13. Transcriptomic Insight Into the Polygenic Mechanisms Underlying Psychiatric Disorders. Biol Psychiatry. 2021 01 01; 89(1):54-64. Hernandez LM, Kim M, Hoftman GD, Haney JR, de la Torre-Ubieta L, Pasaniuc B, Gandal MJ. PMID: 32792264; PMCID: PMC7718368.
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    Translation:HumansCells
  14. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 2020 Apr 30; 181(3):745. Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. PMID: 32359439.
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  15. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 2019 10 17; 179(3):750-771.e22. Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. PMID: 31626773; PMCID: PMC8963725.
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    Translation:HumansCells
  16. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. 2019 09 04; 103(5):785-801.e8. Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, Hinz FI, Sabri S, Lowry WE, Gerstein MB, Plath K, Geschwind DH. PMID: 31303374; PMCID: PMC6831089.
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    Translation:HumansCells
  17. VOTING-BASED SEGMENTATION OF OVERLAPPING NUCLEI IN CLARITY IMAGES. Proc IEEE Int Symp Biomed Imaging. 2018 Apr; 2018:658-662. Quachtran B, de la Torre Ubieta L, Yusupova M, Geschwind DH, Shattuck DW. PMID: 32038768; PMCID: PMC7007201.
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  18. Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1. Neuron. 2018 04 04; 98(1):127-141.e7. Vuong CK, Wei W, Lee JA, Lin CH, Damianov A, de la Torre-Ubieta L, Halabi R, Otis KO, Martin KC, O'Dell TJ, Black DL. PMID: 29621484; PMCID: PMC5890944.
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    Translation:AnimalsCells
  19. The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis. Cell. 2018 01 11; 172(1-2):289-304.e18. de la Torre-Ubieta L, Stein JL, Won H, Opland CK, Liang D, Lu D, Geschwind DH. PMID: 29307494; PMCID: PMC5924568.
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    Translation:HumansCells
  20. Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. Cell Rep. 2017 Oct 10; 21(2):517-532. Watanabe M, Buth JE, Vishlaghi N, de la Torre-Ubieta L, Taxidis J, Khakh BS, Coppola G, Pearson CA, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Cheng G, Geschwind DH, Golshani P, Sun R, Novitch BG. PMID: 29020636; PMCID: PMC5637483.
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    Translation:HumansCells
  21. Chromosome conformation elucidates regulatory relationships in developing human brain. Nature. 2016 10 27; 538(7626):523-527. Won H, de la Torre-Ubieta L, Stein JL, Parikshak NN, Huang J, Opland CK, Gandal MJ, Sutton GJ, Hormozdiari F, Lu D, Lee C, Eskin E, Voineagu I, Ernst J, Geschwind DH. PMID: 27760116; PMCID: PMC5358922.
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    Translation:HumansCells
  22. Advancing the understanding of autism disease mechanisms through genetics. Nat Med. 2016 Apr; 22(4):345-61. de la Torre-Ubieta L, Won H, Stein JL, Geschwind DH. PMID: 27050589; PMCID: PMC5072455.
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    Translation:HumansAnimals
  23. Human neural stem cell-derived cultures in three-dimensional substrates form spontaneously functional neuronal networks. J Tissue Eng Regen Med. 2017 04; 11(4):1022-1033. Smith I, Silveirinha V, Stein JL, de la Torre-Ubieta L, Farrimond JA, Williamson EM, Whalley BJ. PMID: 25712225.
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    Translation:HumansCells
  24. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 2014 Jul 02; 83(1):69-86. Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. PMID: 24991955; PMCID: PMC4277209.
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    Translation:HumansCells
  25. A novel Hap1-Tsc1 interaction regulates neuronal mTORC1 signaling and morphogenesis in the brain. J Neurosci. 2013 Nov 13; 33(46):18015-21. Mejia LA, Litterman N, Ikeuchi Y, de la Torre-Ubieta L, Bennett EJ, Zhang C, Harper JW, Bonni A. PMID: 24227713; PMCID: PMC3828457.
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    Translation:HumansAnimalsCells
  26. The XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling link that orchestrates ciliary morphogenesis in postmitotic neurons. Cell Rep. 2013 Sep 12; 4(5):879-89. Ikeuchi Y, de la Torre-Ubieta L, Matsuda T, Steen H, Okazawa H, Bonni A. PMID: 23994472; PMCID: PMC4013279.
    View in: PubMed Mentions: 8 Fields:
    Translation:AnimalsCells
  27. FoxO6 regulates memory consolidation and synaptic function. Genes Dev. 2012 Dec 15; 26(24):2780-801. Salih DA, Rashid AJ, Colas D, de la Torre-Ubieta L, Zhu RP, Morgan AA, Santo EE, Ucar D, Devarajan K, Cole CJ, Madison DV, Shamloo M, Butte AJ, Bonni A, Josselyn SA, Brunet A. PMID: 23222102; PMCID: PMC3533081.
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    Translation:AnimalsCells
  28. A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development. Development. 2011 Dec; 138(23):5257-67. Christensen R, de la Torre-Ubieta L, Bonni A, Colón-Ramos DA. PMID: 22069193; PMCID: PMC3210501.
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    Translation:AnimalsCells
  29. Transcriptional regulation of neuronal polarity and morphogenesis in the mammalian brain. Neuron. 2011 Oct 06; 72(1):22-40. de la Torre-Ubieta L, Bonni A. PMID: 21982366; PMCID: PMC3391704.
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    Translation:HumansAnimalsCells
  30. An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain. Neuron. 2011 Mar 10; 69(5):930-44. Huynh MA, Ikeuchi Y, Netherton S, de la Torre-Ubieta L, Kanadia R, Stegmüller J, Cepko C, Bonni S, Bonni A. PMID: 21382553; PMCID: PMC3073069.
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    Translation:AnimalsCells
  31. A JIP3-regulated GSK3β/DCX signaling pathway restricts axon branching. J Neurosci. 2010 Dec 15; 30(50):16766-76. Bilimoria PM, de la Torre-Ubieta L, Ikeuchi Y, Becker EB, Reiner O, Bonni A. PMID: 21159948; PMCID: PMC3409248.
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    Translation:AnimalsCells
  32. A FOXO-Pak1 transcriptional pathway controls neuronal polarity. Genes Dev. 2010 Apr 15; 24(8):799-813. de la Torre-Ubieta L, Gaudillière B, Yang Y, Ikeuchi Y, Yamada T, DiBacco S, Stegmüller J, Schüller U, Salih DA, Rowitch D, Brunet A, Bonni A. PMID: 20395366; PMCID: PMC2854394.
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    Translation:AnimalsCells
  33. Combinatorial assembly of neurons: from chromatin to dendrites. Trends Cell Biol. 2008 Feb; 18(2):48-51. de la Torre-Ubieta L, Bonni A. PMID: 18222691.
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    Translation:HumansAnimalsCells
  34. The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell. 2007 Mar 23; 128(6):1077-88. Iwase S, Lan F, Bayliss P, de la Torre-Ubieta L, Huarte M, Qi HH, Whetstine JR, Bonni A, Roberts TM, Shi Y. PMID: 17320160.
    View in: PubMed Mentions: 372 Fields:
    Translation:HumansAnimalsCells
  35. Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature. 2006 Jul 27; 442(7101):471-4. Lasorella A, Stegmüller J, Guardavaccaro D, Liu G, Carro MS, Rothschild G, de la Torre-Ubieta L, Pagano M, Bonni A, Iavarone A. PMID: 16810178.
    View in: PubMed Mentions: 150 Fields:
    Translation:HumansCells

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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