Shili Xu • UCLA Profiles (original) (raw)
- Lentivirus-based HPSC therapy provides effective and long-term treatment in hypophosphatasia mouse model. Mol Ther. 2026 Mar 10. Carrillo MA, Tomer S, Wang L, Cook E, Wennerberg W, Tien N, Ng H, Alagarsamy J, Rezek V, Martin H, Narisawa S, Millan JL, Crine P, Yan M, Lee S, Kim NJ, Rodriguez R, Bishop P, Sanchez R, Orpilla J, Le Verche V, Xu S, Chen ISY, Kitchen S, Breton L, Bartlett JS, Do MH, Zhen A. PMID: 41814653.
View in: PubMed Mentions: - The liver regulates ectopic calcification in Abcc6-deficient models of pseudoxanthoma elasticum. J Clin Invest. 2026 May 01; 136(9). Wang Y, Sun B, Ma F, Tao B, Gu Y, Zhou Z, Kim J, Zhang L, Liu Z, Ten Hoeve J, Stiles L, Fernandez Del Rio L, Pan C, Shirihai O, Xu S, Graeber TG, Sallam T, Pellegrini M, Lusis AJ, Deb A. PMID: 41805635; PMCID: PMC13132379.
View in: PubMed Mentions: - Assessment of Bone Regeneration in Rabbit Calvarial Defects Treated With Mineralized Collagen-Based Scaffolds Using In Vivo MicroCT and Three-Dimensional Rendering. Curr Protoc. 2026 Mar; 6(3):e70337. Kang Y, Shariati K, Cascavita CT, Chen W, Bedar M, Ren X, Xu S, Lee JC. PMID: 41769970; PMCID: PMC12951822.
View in: PubMed Mentions: - Evaluating Mineral Deposition in Bone-Regenerative Collagen-Based Scaffolds Using High-Resolution microCT and 3D Computational Segmentation. Curr Protoc. 2026 Jan; 6(1):e70306. Kang Y, Shariati K, Cascavita CT, Ren X, Harley BAC, Xu S, Lee JC. PMID: 41574482; PMCID: PMC12828634.
View in: PubMed Mentions: 1 Fields:
Translation:HumansCells - Overcoming Low-Field Limitations: High-Quality Ex Vivo Soft Tissue Imaging with Compact MRI Systems. Curr Protoc. 2026 Jan; 6(1):e70288. Litwak A, Sarabia A, Tamboline M, Mori S, Xu S. PMID: 41481274; PMCID: PMC12758513.
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Translation:HumansAnimals - Macroscopic and microscopic observations of a helix-fixation type leadless pacemaker 1 month after implantation. HeartRhythm Case Rep. 2026 Feb; 12(2):242-252. Miyazaki Y, Rimmer M, Bender AB, Hanna P, Hayase JH, Do DH, Xu S, Ajijola OA, Fishbein MC, Shivkumar K, Mori S. PMID: 41727305; PMCID: PMC12922532.
View in: PubMed Mentions: - Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: 12-Lead Electrocardiographic Anatomy. JACC Case Rep. 2026 Jan 07; 31(1):105998. Bradfield EP, Rimmer M, Miyazaki Y, Hanna P, Hayase JH, Do DH, Xu S, Yamagami S, Shivkumar K, Mori S. PMID: 41204941; PMCID: PMC12833672.
View in: PubMed Mentions: - Bone Loss and TLR4 Signals Contribute Independently to B Lineage Aging. Aging Cell. 2025 Dec; 24(12):e70267. Baker E, Montecino-Rodriguez E, Xu S, Tetradis S, Rouault A, Estrada OI, Dorshkind K. PMID: 41074552; PMCID: PMC12686596.
View in: PubMed Mentions: Fields:
Translation:AnimalsCells - Three-Dimensional Printing of the Human Pericardium to Facilitate Understanding of the Pericardial Reflections, Recesses, and Sinuses. Circ Cardiovasc Imaging. 2025 Dec; 18(12):e018410. Miyazaki Y, Rimmer M, Peacock WJ, Xu S, Shivkumar K, Mori S. PMID: 40859840; PMCID: PMC12667300.
View in: PubMed Mentions: Fields: - Three-Dimensional Magnetic Resonance Imaging of the Human Stellate Ganglion. Clin Anat. 2025 Jul 23. Nakajo M, Mori S, Nakayama H, Yoshiura T, Xu S, Rimmer M, Sato T, Sato M, Malik V, Salamon N, Zhong X, Nguyen KL, Finn JP, Peacock WJ, Shivkumar K. PMID: 40698794.
View in: PubMed Mentions: 1 Fields: - Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Subclavian Artery and Vein. JACC Case Rep. 2025 Jul 02; 30(17):103896. Sato T, Mori S, Do DH, Rimmer M, Xu S, Yoshioka A, Yamagami S, Ishibashi K, Kusano K, Peacock WJ, Shivkumar K. PMID: 40615188; PMCID: PMC12441354.
View in: PubMed Mentions: - Supramolecular hydrogel actuators with reprogrammable magnetic orientation by locally mediated viscoelasticity and pinning force. Sci Adv. 2025 Jun 27; 11(26):eadw0500. Zhang CW, Hao XP, Zou W, Zhu Z, Hu JY, Hou LX, Xu SR, Luo Z, Yan Y, Sarabia A, Litwak A, Xu S, Wang ZJ, He X, Zheng Q, Wu ZL. PMID: 40577469; PMCID: PMC12204151.
View in: PubMed Mentions: 1 Fields: - Real-Time in Vivo Bacterial Imaging by Computed Tomography and Fluorescence Using Phage-Gold Nanorod Bioconjugates as Contrast Agents. ACS Biomater Sci Eng. 2025 Jun 09; 11(6):3297-3306. Peng H, Vexler S, Xu S, Chen IA. PMID: 40340326; PMCID: PMC12152831.
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Translation:AnimalsCells - Preclinical evaluation of high-resolution CT, 18F-FDG, and 18F-NaF PET imaging for longitudinal monitoring of atherosclerosis. Eur J Nucl Med Mol Imaging. 2025 Sep; 52(11):4256-4267. Tamboline M, Collins J, Jackson W, Gu W, Worssam M, Cheng P, David J, Taschereau R, Chatziioannou AF, Jackson S, Xu S, Ikotun OF. PMID: 40289041; PMCID: PMC12360302.
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Translation:Animals - [18F]FDG-PET and [18F]MPPF-PET are brain biomarkers for the creatine transporter Slc6a8 loss of function mutation. Sci Rep. 2025 Mar 01; 15(1):7280. Day I, Tamboline M, Lueptow L, Zhuravka I, Diep T, Tkachyova I, Xu S, Schulze A, Lipshutz GS. PMID: 40025148; PMCID: PMC11873236.
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Translation:Animals - Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph. J Vis Exp. 2025 02 21; (216). Taschereau R, Chatziioannou AF, Xu S. PMID: 40063521; PMCID: PMC12121557.
View in: PubMed Mentions: 1 Fields:
Translation:Animals - Recent developments in translational imaging of in vivo gene therapy outcomes. Mol Ther. 2025 Jun 04; 33(6):2548-2564. Day IL, Tamboline M, Lipshutz GS, Xu S. PMID: 39741403; PMCID: PMC12172201.
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Translation:HumansAnimals - Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Femoral Artery and Vein: Part 1. JACC Case Rep. 2024 Dec 04; 29(23):102807. Sato T, Mori S, Hanna P, Bender A, Hayase J, Xu S, Yoshioka A, Yamagami S, Toba T, Izawa Y, Shivkumar K. PMID: 39691319; PMCID: PMC11646876.
View in: PubMed Mentions: - Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Femoral Artery and Vein: Part 2. JACC Case Rep. 2024 Dec 04; 29(23):102800. Sato T, Mori S, Hanna P, Bender A, Hayase J, Xu S, Yoshioka A, Yamagami S, Toba T, Izawa Y, Shivkumar K. PMID: 39691332; PMCID: PMC11646903.
View in: PubMed Mentions: 1 - PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity. Proc Natl Acad Sci U S A. 2024 Dec 03; 121(49):e2416882121. Varuzhanyan G, Chen CC, Freeland J, He T, Tran W, Song K, Wang L, Cheng D, Xu S, Dibernardo GA, Esedebe FN, Bhatia V, Han M, Abt ER, Park JW, Memarzadeh S, Shackelford DB, Lee JK, Graeber TG, Shirihai OS, Witte ON. PMID: 39589879; PMCID: PMC11626175.
View in: PubMed Mentions: 8 Fields:
Translation:HumansAnimalsCells - PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity. Cell Rep. 2024 12 24; 43(12):114945. De Siqueira MK, Li G, Zhao Y, Wang S, Ahn IS, Tamboline M, Hildreth AD, Larios J, Schcolnik-Cabrera A, Nouhi Z, Zhang Z, Tol MJ, Pandey V, Xu S, O'Sullivan TE, Mack JJ, Tontonoz P, Sallam T, Wohlschlegel JA, Hulea L, Xiao X, Yang X, Villanueva CJ. PMID: 39579770; PMCID: PMC12002411.
View in: PubMed Mentions: 2 Fields:
Translation:AnimalsCells - Novel Quantification Protocol for Cardiovascular Calcification Progression Using Longitudinal MicroPET/MicroCT Images. J Vis Exp. 2024 11 15; (213). Day IL, Tamboline M, Litwak A, Sarabia A, Tintut Y, Demer LL, Xu S. PMID: 39620591; PMCID: PMC12108129.
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Translation:Animals - A humanized monoclonal antibody targeting an ectonucleotidase rescues cardiac metabolism and heart function after myocardial infarction. Cell Rep Med. 2024 Nov 19; 5(11):101795. Li S, Tao B, Wan J, Montecino-Rodriguez E, Wang P, Ma F, Sun B, Gu Y, Ramadoss S, Su L, Sun Q, Hoeve JT, Stiles L, Collins J, van Dam RM, Tamboline M, Taschereau R, Shirihai O, Kitchen DB, Pellegrini M, Graeber T, Dorshkind K, Xu S, Deb A. PMID: 39454569; PMCID: PMC11604407.
View in: PubMed Mentions: 6 Fields:
Translation:HumansAnimalsCells - A Glucose-Responsive Glucagon-Micelle for the Prevention of Hypoglycemia. ACS Cent Sci. 2024 Nov 27; 10(11):2036-2047. Vinciguerra D, Yang J, Georgiou PG, Snell K, Pesenti T, Collins J, Tamboline M, Xu S, van Dam RM, Messina KMM, Hevener AL, Maynard HD. PMID: 39634211; PMCID: PMC11613347.
View in: PubMed Mentions: - PGC-1α drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity. bioRxiv. 2024 Jul 25. Varuzhanyan G, Chen CC, Freeland J, He T, Tran W, Song K, Wang L, Cheng D, Xu S, Dibernardo GA, Esedebe FN, Bhatia V, Han M, Abt ER, Park JW, Memarzadeh S, Shackelford D, Lee JK, Graeber T, Shirihai O, Witte O. PMID: 38645232; PMCID: PMC11030384.
View in: PubMed Mentions: - Pipeline for Multi-Scale Three-Dimensional Anatomic Study of the Human Heart. J Vis Exp. 2024 06 28; (208). Hanna P, Mori S, Sato T, Xu S. PMID: 39007558.
View in: PubMed Mentions: 2 Fields:
Translation:Humans - 89Zr-ImmunoPET for the Specific Detection of EMP2-Positive Tumors. Mol Cancer Ther. 2024 Jun 04; 23(6):890-903. Chan AM, Olafsen T, Tsui J, Salazar FB, Aguirre B, Zettlitz KA, Condro M, Wu AM, Braun J, Gordon LK, Ashki N, Whitelegge J, Xu S, Ikotun O, Lee JT, Wadehra M. PMID: 38417138.
View in: PubMed Mentions: 3 Fields:
Translation:HumansAnimalsCells - Invasive electrochemical impedance spectroscopy with phase delay for experimental atherosclerosis phenotyping. FASEB J. 2024 May 31; 38(10):e23700. Chen M, Neverova N, Xu S, Suwannaphoom K, Lluri G, Tamboline M, Duarte S, Fishbein MC, Luo Y, Packard RRS. PMID: 38787606; PMCID: PMC11759406.
View in: PubMed Mentions: 1 Fields:
Translation:AnimalsCells - Real-time resolution studies of the regulation of lactate production by hexokinases binding to mitochondria in single cells. PLoS One. 2024; 19(3):e0300150. John S, Calmettes G, Xu S, Ribalet B. PMID: 38457438; PMCID: PMC10923494.
View in: PubMed Mentions: 1 Fields:
Translation:HumansCells - 18F-Labeled brain-penetrant EGFR tyrosine kinase inhibitors for PET imaging of glioblastoma. Chem Sci. 2023 Dec 06; 14(47):13825-13831. Narayanam MK, Tsang JE, Xu S, Nathanson DA, Murphy JM. PMID: 38075671; PMCID: PMC10699577.
View in: PubMed Mentions: 3 - Real-time resolution studies of the regulation of pyruvate-dependent lactate metabolism by hexokinases in single cells. PLoS One. 2023; 18(11):e0286660. John S, Calmettes G, Xu S, Ribalet B. PMID: 37917627; PMCID: PMC10621844.
View in: PubMed Mentions: 3 Fields:
Translation:HumansCells - M2 isoform of pyruvate kinase rewires glucose metabolism during radiation therapy to promote an antioxidant response and glioblastoma radioresistance. Neuro Oncol. 2023 11 02; 25(11):1989-2000. Bailleul J, Ruan Y, Abdulrahman L, Scott AJ, Yazal T, Sung D, Park K, Hoang H, Nathaniel J, Chu FI, Palomera D, Sehgal A, Tsang JE, Nathanson DA, Xu S, Park JO, Ten Hoeve J, Bhat K, Qi N, Kornblum HI, Schaue D, McBride WH, Lyssiotis CA, Wahl DR, Vlashi E. PMID: 37279645; PMCID: PMC10628945.
View in: PubMed Mentions: 8 Fields:
Translation:HumansCells - Flexible 3-D Electrochemical Impedance Spectroscopy Sensors Incorporating Phase Delay for Comprehensive Characterization of Atherosclerosis. bioRxiv. 2023 Sep 22. Chen M, Neverova N, Xu S, Suwannaphoom K, Lluri G, Tamboline M, Duarte S, Fishbein MC, Luo Y, Packard RRS. PMID: 37786712; PMCID: PMC10541620.
View in: PubMed Mentions: - Spatial mapping of mitochondrial networks and bioenergetics in lung cancer. Nature. 2023 03; 615(7953):712-719. Han M, Bushong EA, Segawa M, Tiard A, Wong A, Brady MR, Momcilovic M, Wolf DM, Zhang R, Petcherski A, Madany M, Xu S, Lee JT, Poyurovsky MV, Olszewski K, Holloway T, Gomez A, John MS, Dubinett SM, Koehler CM, Shirihai OS, Stiles L, Lisberg A, Soatto S, Sadeghi S, Ellisman MH, Shackelford DB. PMID: 36922590; PMCID: PMC10033418.
View in: PubMed Mentions: 67 Fields:
Translation:HumansCells - Poly(trehalose methacrylate) as an Excipient for Insulin Stabilization: Mechanism and Safety. ACS Appl Mater Interfaces. 2022 Aug 24; 14(33):37410-37423. Gelb MB, Messina KMM, Vinciguerra D, Ko JH, Collins J, Tamboline M, Xu S, Ibarrondo FJ, Maynard HD. PMID: 35968684; PMCID: PMC9412841.
View in: PubMed Mentions: 5 Fields:
Translation:Animals - Low-dose exposure to PBDE disrupts genomic integrity and innate immunity in mammary tissue. Front Genet. 2022; 13:904607. Lamkin DM, Chen S, Bradshaw KP, Xu S, Faull KF, Sloan EK, Cole SW. PMID: 36035174; PMCID: PMC9413140.
View in: PubMed Mentions: 7 - Giant Magnetoelastic Effect Enabled Stretchable Sensor for Self-Powered Biomonitoring. ACS Nano. 2022 Apr 26; 16(4):6013-6022. Zhao X, Chen G, Zhou Y, Nashalian A, Xu J, Tat T, Song Y, Libanori A, Xu S, Li S, Chen J. PMID: 35417654.
View in: PubMed Mentions: 15 Fields:
Translation:HumansAnimalsPHPublic Health - Gene therapy for guanidinoacetate methyltransferase deficiency restores cerebral and myocardial creatine while resolving behavioral abnormalities. Mol Ther Methods Clin Dev. 2022 Jun 09; 25:278-296. Khoja S, Lambert J, Nitzahn M, Eliav A, Zhang Y, Tamboline M, Le CT, Nasser E, Li Y, Patel P, Zhuravka I, Lueptow LM, Tkachyova I, Xu S, Nissim I, Schulze A, Lipshutz GS. PMID: 35505663; PMCID: PMC9051621.
View in: PubMed Mentions: 4 - Positron Emission Tomography Tracer Design of Targeted Synthetic Peptides via 18F-Sydnone Alkyne Cycloaddition. Bioconjug Chem. 2021 Sep 15; 32(9):2073-2082. Narayanam MK, Lai BT, Loredo JM, Wilson JA, Eliasen AM, LaBerge NA, Nason M, Cantu AL, Luton BK, Xu S, Agnew HD, Murphy JM. PMID: 34415731.
View in: PubMed Mentions: 6 Fields:
Translation:HumansAnimalsCells - Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients. Proc Natl Acad Sci U S A. 2021 03 16; 118(11). Yang L, Yan X, Chen J, Zhan Q, Hua Y, Xu S, Li Z, Wang Z, Dong Y, Zuo D, Xue M, Tang Y, Herschman HR, Lu S, Shi Q, Wei W. PMID: 33836566; PMCID: PMC7980452.
View in: PubMed Mentions: 35 Fields:
Translation:HumansCells - Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer. Sci Rep. 2020 01 15; 10(1):377. Li R, Ong SL, Tran LM, Jing Z, Liu B, Park SJ, Huang ZL, Walser TC, Heinrich EL, Lee G, Salehi-Rad R, Crosson WP, Pagano PC, Paul MK, Xu S, Herschman H, Krysan K, Dubinett S. PMID: 31941995; PMCID: PMC6962381.
View in: PubMed Mentions: 60 Fields:
Translation:HumansCells - Histone deacetylase inhibition is synthetically lethal with arginine deprivation in pancreatic cancers with low argininosuccinate synthetase 1 expression. Theranostics. 2020; 10(2):829-840. Kim SS, Xu S, Cui J, Poddar S, Le TM, Hayrapetyan H, Li L, Wu N, Moore AM, Zhou L, Yu AC, Dann AM, Elliott IA, Abt ER, Kim W, Dawson DW, Radu CG, Donahue TR. PMID: 31903153; PMCID: PMC6929997.
View in: PubMed Mentions: 18 Fields:
Translation:HumansAnimalsCells - Comparison of the Efficacy and Sensitivity of Alternative PET Reporter Gene/PET Reporter Probe Systems That Minimize Biological Variables. Methods Mol Biol. 2020; 2126:177-190. Xu S, Herschman HR. PMID: 32112389.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimalsCells - Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell Chem Biol. 2020 02 20; 27(2):197-205.e6. Abt ER, Rosser EW, Durst MA, Lok V, Poddar S, Le TM, Cho A, Kim W, Wei L, Song J, Capri JR, Xu S, Wu N, Slavik R, Jung ME, Damoiseaux R, Czernin J, Donahue TR, Lavie A, Radu CG. PMID: 31734178; PMCID: PMC7035983.
View in: PubMed Mentions: 21 Fields:
Translation:HumansCells - A Tumor Agnostic Therapeutic Strategy for Hexokinase 1-Null/Hexokinase 2-Positive Cancers. Cancer Res. 2019 Dec 01; 79(23):5907-5914. Xu S, Herschman HR. PMID: 31434645; PMCID: PMC12139393.
View in: PubMed Mentions: 75 Fields:
Translation:HumansAnimalsCells - Identification, synthesis and evaluation of CSF1R inhibitors using fragment based drug design. Comput Biol Chem. 2019 Jun; 80:374-383. Machiraju PK, Yedla P, Gubbala SP, Bohari T, Abdul JKV, Xu S, Patel R, Chittireddy VRR, Boppana K, Jagarlapudi SARP, Neamati N, Syed R, Amanchy R. PMID: 31103918.
View in: PubMed Mentions: 4 Fields:
Translation:HumansCells - Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes. Theranostics. 2019; 9(8):2282-2298. Xu S, Liu Y, Yang K, Wang H, Shergalis A, Kyani A, Bankhead A, Tamura S, Yang S, Wang X, Wang CC, Rehemtulla A, Ljungman M, Neamati N. PMID: 31149044; PMCID: PMC6531306.
View in: PubMed Mentions: 26 Fields:
Translation:HumansAnimalsCells - Lysosome inhibition sensitizes pancreatic cancer to replication stress by aspartate depletion. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):6842-6847. Elliott IA, Dann AM, Xu S, Kim SS, Abt ER, Kim W, Poddar S, Moore A, Zhou L, Williams JL, Capri JR, Ghukasyan R, Matsumura C, Tucker DA, Armstrong WR, Cabebe AE, Wu N, Li L, Le TM, Radu CG, Donahue TR. PMID: 30894490; PMCID: PMC6452719.
View in: PubMed Mentions: 33 Fields:
Translation:HumansAnimalsCells - An HK2 Antisense Oligonucleotide Induces Synthetic Lethality in HK1-HK2+ Multiple Myeloma. Cancer Res. 2019 05 15; 79(10):2748-2760. Xu S, Zhou T, Doh HM, Trinh KR, Catapang A, Lee JT, Braas D, Bayley NA, Yamada RE, Vasuthasawat A, Sasine JP, Timmerman JM, Larson SM, Kim Y, MacLeod AR, Morrison SL, Herschman HR. PMID: 30885978; PMCID: PMC6522331.
View in: PubMed Mentions: 35 Fields:
Translation:HumansAnimalsCells - Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling. Cell Rep. 2018 12 04; 25(10):2919-2934.e8. Argus JP, Wilks MQ, Zhou QD, Hsieh WY, Khialeeva E, Hoi XP, Bui V, Xu S, Yu AK, Wang ES, Herschman HR, Williams KJ, Bensinger SJ. PMID: 30517876; PMCID: PMC6432944.
View in: PubMed Mentions: 8 Fields:
Translation:HumansAnimalsCells - A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. Cancer Metab. 2018; 6:7. Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. PMID: 29988332; PMCID: PMC6022704.
View in: PubMed Mentions: 16 - Hexokinase 2 is targetable for HK1 negative, HK2 positive tumors from a wide variety of tissues of origin. J Nucl Med. 2018 Jun 07. Xu S, Catapang A, Doh HM, Bayley NA, Lee JT, Braas D, Graeber TG, Herschman HR. PMID: 29880505; PMCID: PMC8833855.
View in: PubMed Mentions: 15 Fields: - Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. Nat Commun. 2016 Apr 29; 7:11457. Krall AS, Xu S, Graeber TG, Braas D, Christofk HR. PMID: 27126896; PMCID: PMC4855534.
View in: PubMed Mentions: 294 Fields:
Translation:HumansCells - A review on PARP1 inhibitors: Pharmacophore modeling, virtual and biological screening studies to identify novel PARP1 inhibitors. Curr Top Med Chem. 2014; 14(17):2020-30. Singh SS, Sarma JA, Narasu L, Dayam R, Xu S, Neamati N. PMID: 25262797.
View in: PubMed Mentions: 3 Fields:
Translation:Humans - Protein disulfide isomerase: a promising target for cancer therapy. Drug Discov Today. 2014 Mar; 19(3):222-40. Xu S, Sankar S, Neamati N. PMID: 24184531.
View in: PubMed Mentions: 143 Fields:
Translation:HumansAnimalsCells - gp130: a promising drug target for cancer therapy. Expert Opin Ther Targets. 2013 Nov; 17(11):1303-28. Xu S, Neamati N. PMID: 24099136.
View in: PubMed Mentions: 32 Fields:
Translation:HumansCells - Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. PLoS One. 2013; 8(7):e69484. Adisetiyo H, Liang M, Liao CP, Aycock-Williams A, Cohen MB, Xu S, Neamati N, Conway EM, Cheng CY, Nikitin AY, Roy-Burman P. PMID: 23936028; PMCID: PMC3729965.
View in: PubMed Mentions: 11 Fields:
Translation:HumansAnimals - Synthesis and SAR studies of marine natural products ma'edamines A, B and their analogues. Bioorg Med Chem Lett. 2013 Sep 15; 23(18):5135-9. Saha S, Reddy ChV, Xu S, Sankar S, Neamati N, Patro B. PMID: 23927972.
View in: PubMed Mentions: 6 Fields:
Translation:HumansCells - Discovery of a novel orally active small-molecule gp130 inhibitor for the treatment of ovarian cancer. Mol Cancer Ther. 2013 Jun; 12(6):937-49. Xu S, Grande F, Garofalo A, Neamati N. PMID: 23536726.
View in: PubMed Mentions: 70 Fields:
Translation:HumansAnimalsCells - Stabilization of MDA-7/IL-24 for colon cancer therapy. Cancer Lett. 2013 Jul 28; 335(2):421-30. Xu S, Oshima T, Imada T, Masuda M, Debnath B, Grande F, Garofalo A, Neamati N. PMID: 23481022.
View in: PubMed Mentions: 20 Fields:
Translation:HumansCells - Small molecule inhibitors of CXCR4. Theranostics. 2013; 3(1):47-75. Debnath B, Xu S, Grande F, Garofalo A, Neamati N. PMID: 23382786; PMCID: PMC3563081.
View in: PubMed Mentions: 126 Fields:
Translation:HumansAnimals - Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties. J Med Chem. 2012 Nov 26; 55(22):9492-509. Zeng LF, Wang Y, Kazemi R, Xu S, Xu ZL, Sanchez TW, Yang LM, Debnath B, Odde S, Xie H, Zheng YT, Ding J, Neamati N, Long YQ. PMID: 23098137.
View in: PubMed Mentions: 9 Fields:
Translation:HumansCells - Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16348-53. Xu S, Butkevich AN, Yamada R, Zhou Y, Debnath B, Duncan R, Zandi E, Petasis NA, Neamati N. PMID: 22988091; PMCID: PMC3479552.
View in: PubMed Mentions: 115 Fields:
Translation:HumansAnimalsCells - Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein. J Med Chem. 2012 Aug 09; 55(15):6645-68. Debnath B, Xu S, Neamati N. PMID: 22650325.
View in: PubMed Mentions: 84 Fields:
Translation:HumansAnimalsCells - Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update. Curr Pharm Des. 2011; 17(6):536-59. Millard M, Pathania D, Grande F, Xu S, Neamati N. PMID: 21391905.
View in: PubMed Mentions: 27 Fields:
Translation:Humans - Biological evaluation of paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery. Cancer Biol Ther. 2010 Feb; 9(3):192-203. Yamada R, Kostova MB, Anchoori RK, Xu S, Neamati N, Khan SR. PMID: 20023432.
View in: PubMed Mentions: 10 Fields:
Translation:HumansAnimalsCells - A chemical lipid modification of recombinant preS antigen to study the mechanism of HBV attachment to the host cell. J Biotechnol. 2008 Oct 10; 137(1-4):8-13. Chen B, Lian M, Xu S, Luo M, Zheng X. PMID: 18675858.
View in: PubMed Mentions: Fields:
Translation:HumansCells
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