Christopher Toomey • UCSD Profiles (original) (raw)

  1. Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation. Prog Retin Eye Res. 2026 Mar; 111:101449. Stuard Sambhariya W, Bowes Rickman C, D'Amore PA, Corradetti G, Hageman GS, Howell GR, Marola OJ, Phatnani H, Philp NJ, Sinha D, Toomey CB, Stone F, Eberhart C, Handa JT. PMID: 41708012; PMCID: PMC12949356.
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  2. Longitudinal Metabolic Trajectories in Diabetes Prevention Program Participants Reveal Subgroups With Varying Micro- and Macrovascular Complication Risks. Diabetes Care. 2025 Oct 01; 48(10):1704-1712. Kobayashi E, Linden-Santangeli NJ, Chan N, Toomey CB, Mudaliar S, Temprosa M, Edelstein S, Goyal R, Rangamani P, Majithia AR, Diabetes Prevention Program Research Group . PMID: 40857122; PMCID: PMC12451836.
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    Translation:Humans
  3. Reply. Ophthalmology. 2025 Dec; 132(12):e195-e196. Chen JS, Esko JD, Gordts PLSM, Walker E, Baxter SL, Toomey CB. PMID: 41003470.
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  4. Bruch's membrane heparan sulfate retains lipoproteins in the early stages of age-related macular degeneration. Proc Natl Acad Sci U S A. 2025 Jun 17; 122(24):e2500727122. Toomey CB, Pflugmacher S, Park K, Pihl J, Weiser Novak S, Rodriguez J, Jalali M, Jung J, Mozafari M, Omran SP, Pormir CK, Hauer J, Painter C, Walker E, Huang AS, Boassa D, Handa JT, Aastrup T, Gordts PLSM, Esko JD. PMID: 40512794; PMCID: PMC12184332.
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    Translation:Humans
  5. The Sialome of the Retina, Alteration in Age-Related Macular Degeneration Pathology, and Potential Impacts on Complement Factor H. Invest Ophthalmol Vis Sci. 2025 Jun 02; 66(6):81. Swan J, Toomey CB, Bergstrand M, Cuello HA, Robie J, Yu H, Yuan Y, Kooner AS, Chen X, Shaughnessy J, Ram S, Varki A, Gagneux P. PMID: 40576434; PMCID: PMC12212450.
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    Translation:Humans
  6. Breaking Bruch's: How changes in Bruch's membrane influence retinal homeostasis. Exp Eye Res. 2025 Jun; 255:110343. Clark SJ, Curcio C, Dick AD, Doyle S, Edwards M, Flores-Bellver M, Hass D, Lennon R, Toomey CB, Rohrer B. PMID: 40107443.
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  7. The sialome of the retina, alteration in age-related macular degeneration (AMD) pathology and potential impacts on Complement Factor H. bioRxiv. 2025 Mar 13. Swan J, Toomey CB, Bergstrand M, Cuello HA, Robie J, Yu H, Yuan Y, Kooner AS, Chen X, Shaughnessy J, Ram S, Varki A, Gagneux P. PMID: 40161805; PMCID: PMC11952305.
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  8. Response to Letter to the Editor: Visual Outcomes after Hyperbaric Oxygen Therapy. Retina. 2025 Mar 05. Toomey CB, Kalaw FGP, Walker E, Freeman WR. PMID: 40068192.
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  9. Development of an image-guided non-vitrectomy subretinal access approach for trans-scleral cell and gene therapy delivery. bioRxiv. 2025 Mar 01. Singh MS, Guo S, Toomey CB, McNally M, Harris-Bookman S, Li K, Agakishiev D, Wei S, Lee S, Perrino K, Wolfe KC, Kang JU. PMID: 40060673; PMCID: PMC11888455.
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  10. High-Density Lipoproteins Associated with Age-Related Macular Degeneration in the All of Us Research Program. Ophthalmology. 2025 Jun; 132(6):684-691. Chen JS, Esko JD, Walker E, Gordts PLSM, Baxter SL, Toomey CB. PMID: 39756691; PMCID: PMC12097936.
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    Translation:Humans
  11. OCT Changes Observed during the Progression of Early Age-Related Macular Degeneration. Ophthalmol Sci. 2025 Jan-Feb; 5(1):100615. Heckenlaible NJ, Toomey CB, Handa JT. PMID: 39584182; PMCID: PMC11584586.
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  12. Evaluation of Retinal Arterial Occlusion and its Visual and Systemic Prognosis after Hyperbaric Oxygen Therapy. Retina. 2024 Aug 14. Kalaw FGP, Chartrand N, Wedekind L, Chen JS, Lin AC, Koretz Z, Meller L, Oca M, Jagadeesh V, Wilson K, Walker E, Freeman WR, Toomey CB. PMID: 39163734.
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  13. The Sensitivity of Ultra-Widefield Fundus Photography Versus Scleral Depressed Examination for Detection of Retinal Horseshoe Tears. Am J Ophthalmol. 2023 Nov; 255:155-160. Lin AC, Kalaw FGP, Schönbach EM, Song D, Koretz Z, Walker E, Breazzano MP, Scott NL, Borooah S, Ferreyra H, Spencer DB, Goldbaum MH, Nudleman ED, Freeman WR, Toomey CB. PMID: 37468086.
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  14. Greater Outflow Facility Increase After Targeted Trabecular Bypass in Angiographically Determined Low-low Regions. Ophthalmol Glaucoma. 2023 Nov-Dec; 6(6):570-579. Strohmaier CA, Wanderer D, Zhang X, Agarwal D, Toomey CB, Wahlin K, Zhang HF, Stamer WD, Weinreb RN, McDonnell FS, Huang AS. PMID: 37348815; PMCID: PMC10917462.
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    Translation:HumansAnimals
  15. Pseudobleb of silicone oil-related progressive staphylomatous scleral ectasia. J Fr Ophtalmol. 2023 03; 46(3):308-309. Toomey CB, Akpek E, Breazzano MP. PMID: 36682953; PMCID: PMC9992274.
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    Translation:Humans
  16. Prevalence of subclinical retinal ischemia in patients with cardiovascular disease - a hypothesis driven study. EClinicalMedicine. 2021 Mar; 33:100775. Long CP, Chan AX, Bakhoum CY, Toomey CB, Madala S, Garg AK, Freeman WR, Goldbaum MH, DeMaria AN, Bakhoum MF. PMID: 33842865; PMCID: PMC8020165.
    View in: PubMed Mentions: 27
  17. PREVALENCE OF MISMATCH REPAIR GENE MUTATIONS IN UVEAL MELANOMA. Retina. 2020 Nov; 40(11):2216-2220. Toomey CB, Protopsaltis NJ, Phou S, Bakhoum MF, Thorson JA, Ediriwickrema LS, Korn BS, Kikkawa DO, Goldbaum MH, Lin JH. PMID: 32032254.
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    Translation:HumansCells
  18. Mechanisms of Environment-Induced Autoimmunity. Annu Rev Pharmacol Toxicol. 2021 01 06; 61:135-157. Pollard KM, Cauvi DM, Mayeux JM, Toomey CB, Peiss AK, Hultman P, Kono DH. PMID: 32857688; PMCID: PMC8166384.
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    Translation:HumansPHPublic Health
  19. Initiatives to reduce the inappropriate use of proton pump inhibitors in an outpatient primary care clinic. Ann Pharm Fr. 2020 11; 78(6):497-498. Kudaravalli P, Doobay R, Carvounis C, Toomey C, Dhamoon A. PMID: 32485143.
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    Translation:Humans
  20. Rifabutin-Cobicistat Drug Interaction Resulting in Severe Bilateral Panuveitis. Case Rep Ophthalmol. 2020 Jan-Apr; 11(1):156-160. Toomey CB, Lee J, Spencer DB. PMID: 32399018; PMCID: PMC7204858.
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  21. A Case of Unilateral Coccidioidal Chorioretinitis in a Patient with HIV-Associated Meningoencephalitis. Case Rep Ophthalmol Med. 2019; 2019:1475628. Toomey CB, Gross A, Lee J, Spencer DB. PMID: 31687242; PMCID: PMC6800899.
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  22. Beware of the sneeze. Surv Ophthalmol. 2020 Sep - Oct; 65(5):592-596. Yang P, Toomey CB, Lin J, Kikkawa DO, Korn BS, Harrison A. PMID: 30978335.
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    Translation:Humans
  23. Immediate Release of Gastrin-Releasing Peptide Mediates Delayed Radiation-Induced Pulmonary Fibrosis. Am J Pathol. 2019 05; 189(5):1029-1040. Tighe RM, Heck K, Soderblom E, Zhou S, Birukova A, Young K, Rouse D, Vidas J, Komforti MK, Toomey CB, Cuttitta F, Sunday ME. PMID: 30898588; PMCID: PMC6521890.
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    Translation:AnimalsPHPublic Health
  24. Mercury-induced inflammation and autoimmunity. Biochim Biophys Acta Gen Subj. 2019 12; 1863(12):129299. Pollard KM, Cauvi DM, Toomey CB, Hultman P, Kono DH. PMID: 30742953; PMCID: PMC6689266.
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    Translation:HumansAnimals
  25. GNAQ and PMS1 Mutations Associated with Uveal Melanoma, Ocular Surface Melanosis, and Nevus of Ota. Ocul Oncol Pathol. 2019 Jun; 5(4):267-272. Toomey CB, Fraser K, Thorson JA, Goldbaum MH, Lin JH. PMID: 31367589; PMCID: PMC6615330.
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  26. Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2018 02 01; 59(2):662-673. Toomey CB, Landowski M, Klingeborn M, Kelly U, Deans J, Dong H, Harrabi O, Van Blarcom T, Yeung YA, Grishanin R, Lin JC, Saban DR, Bowes Rickman C. PMID: 29392311; PMCID: PMC5795897.
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    Translation:Animals
  27. Knee confidence in youth and young adults at risk of post-traumatic osteoarthritis 3-10 years following intra-articular knee injury. J Sci Med Sport. 2018 Jul; 21(7):671-675. Ezzat AM, Whittaker JL, Toomey C, Doyle-Baker PK, Brussoni M, Emery CA. PMID: 29233667.
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    Translation:Humans
  28. Complement factor H in AMD: Bridging genetic associations and pathobiology. Prog Retin Eye Res. 2018 01; 62:38-57. Toomey CB, Johnson LV, Bowes Rickman C. PMID: 28928087; PMCID: PMC5776047.
    View in: PubMed Mentions: 97 Fields:
    Translation:Humans
  29. From the Cover: Interplay Between IFN-γ and IL-6 Impacts the Inflammatory Response and Expression of Interferon-Regulated Genes in Environmental-Induced Autoimmunity. Toxicol Sci. 2017 07 01; 158(1):227-239. Cauvi DM, Cauvi G, Toomey CB, Jacquinet E, Pollard KM. PMID: 28453771; PMCID: PMC6075572.
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    Translation:AnimalsCells
  30. Long-term survival following open versus thoracoscopic lobectomy after preoperative chemotherapy for non-small cell lung cancer. Eur J Cardiothorac Surg. 2016 Jun; 49(6):1615-23. Yang CF, Meyerhoff RR, Mayne NR, Singhapricha T, Toomey CB, Speicher PJ, Hartwig MG, Tong BC, Onaitis MW, Harpole DH, D'Amico TA, Berry MF. PMID: 26719408; PMCID: PMC4867396.
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    Translation:Humans
  31. The body composition phenotype of Irish adults aged 18-81 years. Ir J Med Sci. 2016 May; 185(2):537-44. Toomey C, Leahy S, McCreesh K, Coote S, Jakeman P. PMID: 26265025.
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    Translation:Humans
  32. Regulation of age-related macular degeneration-like pathology by complement factor H. Proc Natl Acad Sci U S A. 2015 Jun 09; 112(23):E3040-9. Toomey CB, Kelly U, Saban DR, Bowes Rickman C. PMID: 25991857; PMCID: PMC4466717.
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    Translation:AnimalsCells
  33. Long-Term Outcomes of Lobectomy for Non-Small Cell Lung Cancer After Definitive Radiation Treatment. Ann Thorac Surg. 2015 Jun; 99(6):1914-20. Yang CF, Meyerhoff RR, Stephens SJ, Singhapricha T, Toomey CB, Anderson KL, Kelsey C, Harpole D, D'Amico TA, Berry MF. PMID: 25886806; PMCID: PMC4458187.
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    Translation:Humans
  34. Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice. Am J Pathol. 2015 Jan; 185(1):29-42. Ding JD, Kelly U, Landowski M, Toomey CB, Groelle M, Miller C, Smith SG, Klingeborn M, Singhapricha T, Jiang H, Frank MM, Bowes Rickman C. PMID: 25447048; PMCID: PMC4278241.
    View in: PubMed Mentions: 39 Fields:
    Translation:HumansAnimals
  35. Cathepsin B regulates the appearance and severity of mercury-induced inflammation and autoimmunity. Toxicol Sci. 2014 Dec; 142(2):339-49. Toomey CB, Cauvi DM, Hamel JC, Ramirez AE, Pollard KM. PMID: 25237059; PMCID: PMC4250846.
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    Translation:AnimalsCells
  36. The role of decay accelerating factor in environmentally induced and idiopathic systemic autoimmune disease. Autoimmune Dis. 2014; 2014:452853. Toomey CB, Cauvi DM, Pollard KM. PMID: 24592327; PMCID: PMC3921935.
    View in: PubMed Mentions: 9
  37. Interferon-γ and systemic autoimmunity. Discov Med. 2013 Sep; 16(87):123-31. Pollard KM, Cauvi DM, Toomey CB, Morris KV, Kono DH. PMID: 23998448; PMCID: PMC3934799.
    View in: PubMed Mentions: 148 Fields:
    Translation:HumansAnimals
  38. Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity. J Autoimmun. 2012 Dec; 39(4):323-31. Pollard KM, Hultman P, Toomey CB, Cauvi DM, Hoffman HM, Hamel JC, Kono DH. PMID: 22578563; PMCID: PMC3570757.
    View in: PubMed Mentions: 19 Fields:
    Translation:AnimalsCells
  39. Depletion of complement does not impact initiation of xenobiotic-induced autoimmune disease. Immunology. 2012 Apr; 135(4):333-43. Cauvi DM, Toomey CB, Pollard KM. PMID: 22136142; PMCID: PMC3372748.
    View in: PubMed Mentions: 5 Fields:
    Translation:AnimalsCells
  40. β2-microglobulin is required for the full expression of xenobiotic-induced systemic autoimmunity. J Immunotoxicol. 2011 Jul-Sep; 8(3):228-37. Pollard KM, Hultman P, Toomey CB, Cauvi DM, Kono DH, Konoc DH. PMID: 21793797; PMCID: PMC3257888.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
  41. Decay-accelerating factor 1 (Daf1) deficiency exacerbates xenobiotic-induced autoimmunity. Immunology. 2010 Sep; 131(1):99-106. Toomey CB, Cauvi DM, Song WC, Pollard KM. PMID: 20408894; PMCID: PMC2966762.
    View in: PubMed Mentions: 9 Fields:
    Translation:AnimalsCells

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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