Janelle Ayres • UCSD Profiles (original) (raw)

  1. Dietary methionine mitigates immune-mediated damage by enhancing renal clearance of cytokines. Cell Metab. 2026 Feb 03; 38(2):298-315.e6. Troha K, Kambhampati S, Insenga A, Metallo CM, Ayres JS. PMID: 41576934; PMCID: PMC12834484.
    View in: PubMed Mentions: Fields:
    Translation:AnimalsCells
  2. Pre-infection cerebral cortex structure predicts murine sepsis outcome. PLoS One. 2025; 20(9):e0330947. Gallant RM, Alam S, Venkataraman K, McKenna BS, Khairy K, Ayres JS. PMID: 40961093; PMCID: PMC12443313.
    View in: PubMed Mentions: Fields:
    Translation:Animals
  3. Fluoxetine promotes IL-10-dependent metabolic defenses to protect from sepsis-induced lethality. Sci Adv. 2025 Feb 14; 11(7):eadu4034. Gallant RM, Sanchez KK, Joulia E, Snyder JM, Metallo CM, Ayres JS. PMID: 39951524; PMCID: PMC11827869.
    View in: PubMed Mentions: 5 Fields:
    Translation:HumansAnimals
  4. Host-encoded antivirulence defenses: host physiologies teach pathogens to play nice. Curr Opin Immunol. 2024 Dec; 91:102472. Ayres JS. PMID: 39383570.
    View in: PubMed Mentions: Fields:
    Translation:HumansAnimalsCells
  5. Fluoxetine promotes immunometabolic defenses to mediate host-pathogen cooperation during sepsis. bioRxiv. 2023 Nov 18. Gallant RM, Snyder JM, Ayres JS. PMID: 38013994; PMCID: PMC10680848.
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  6. Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression. Cell Rep. 2023 08 29; 42(8):112997. Fu T, Huan T, Rahman G, Zhi H, Xu Z, Oh TG, Guo J, Coulter S, Tripathi A, Martino C, McCarville JL, Zhu Q, Cayabyab F, Low B, He M, Xing S, Vargas F, Yu RT, Atkins A, Liddle C, Ayres J, Raffatellu M, Dorrestein PC, Downes M, Knight R, Evans RM. PMID: 37611587; PMCID: PMC10903535.
    View in: PubMed Mentions: 41 Fields:
    Translation:Animals
  7. CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection. Cell Rep. 2023 08 29; 42(8):112814. Redford SE, Varanasi SK, Sanchez KK, Thorup NR, Ayres JS. PMID: 37490905; PMCID: PMC12153691.
    View in: PubMed Mentions: 10 Fields:
    Translation:AnimalsCells
  8. Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. Sci Adv. 2023 06 23; 9(25):eadg8719. Chen GY, Thorup NR, Miller AJ, Li YC, Ayres JS. PMID: 37352357; PMCID: PMC10289649.
    View in: PubMed Mentions: 1 Fields:
    Translation:Animals
  9. Cachexia: A systemic consequence of progressive, unresolved disease. Cell. 2023 04 27; 186(9):1824-1845. Ferrer M, Anthony TG, Ayres JS, Biffi G, Brown JC, Caan BJ, Cespedes Feliciano EM, Coll AP, Dunne RF, Goncalves MD, Grethlein J, Heymsfield SB, Hui S, Jamal-Hanjani M, Lam JM, Lewis DY, McCandlish D, Mustian KM, O'Rahilly S, Perrimon N, White EP, Janowitz T. PMID: 37116469; PMCID: PMC11059056.
    View in: PubMed Mentions: 115 Fields:
    Translation:Humans
  10. Age-dependent roles of cardiac remodeling in sepsis defense and pathogenesis. bioRxiv. 2023 Mar 15. Sanchez KK, McCarville JL, Stengel SJ, Snyder JM, Williams AE, Ayres JS. PMID: 36993409; PMCID: PMC10055033.
    View in: PubMed Mentions: 1
  11. Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. bioRxiv. 2023 Feb 26. Chen GY, Thorup NR, Miller AJ, Li YC, Ayres JS. PMID: 36711884; PMCID: PMC9882269.
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  12. Chronic Leptin Deficiency Improves Tolerance of Physiological Damage and Host-Pathogen Cooperation during Yersinia pseudotuberculosis Infection. Infect Immun. 2022 09 15; 90(9):e0024222. Sanchez KK, Troha K, Mu A, Redford SE, McCarville JL, Insenga A, Stengel S, Lee YM, Ayres JS. PMID: 35924898; PMCID: PMC9476980.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansCells
  13. Virulence triggered allergies: Pseudomonas gets the Las laugh. Immunity. 2022 05 10; 55(5):824-826. McCarville JL, Ayres JS. PMID: 35545032.
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    Translation:HumansCells
  14. Adipose triglyceride lipase mediates lipolysis and lipid mobilization in response to iron-mediated negative energy balance. iScience. 2022 Mar 18; 25(3):103941. Romero AR, Mu A, Ayres JS. PMID: 35265813; PMCID: PMC8899412.
    View in: PubMed Mentions: 6
  15. Cooperative defenses during enteropathogenic infection. Curr Opin Microbiol. 2022 02; 65:123-130. Troha K, Ayres JS. PMID: 34847524; PMCID: PMC8818259.
    View in: PubMed Mentions: 4 Fields:
    Translation:HumansCells
  16. Microbiota control of maternal behavior regulates early postnatal growth of offspring. Sci Adv. 2021 01; 7(5). Lee YM, Mu A, Wallace M, Gengatharan JM, Furst AJ, Bode L, Metallo CM, Ayres JS. PMID: 33514556; PMCID: PMC7846171.
    View in: PubMed Mentions: 22 Fields:
    Translation:HumansAnimalsCells
  17. Beyond tug-of-war: Iron metabolism in cooperative host-microbe interactions. PLoS Pathog. 2020 08; 16(8):e1008698. Chen GY, Ayres JS. PMID: 32785251; PMCID: PMC7423093.
    View in: PubMed Mentions: 9 Fields:
    Translation:HumansCells
  18. A metabolic handbook for the COVID-19 pandemic. Nat Metab. 2020 07; 2(7):572-585. Ayres JS. PMID: 32694793; PMCID: PMC7325641.
    View in: PubMed Mentions: 167 Fields:
    Translation:HumansPHPublic Health
  19. Surviving COVID-19: A disease tolerance perspective. Sci Adv. 2020 05; 6(18):eabc1518. Ayres JS. PMID: 32494691; PMCID: PMC7190329.
    View in: PubMed Mentions: 28 Fields:
    Translation:HumansCellsPHPublic Health
  20. Microbiota Metabolites in Health and Disease. Annu Rev Immunol. 2020 04 26; 38:147-170. McCarville JL, Chen GY, Cuevas VD, Troha K, Ayres JS. PMID: 32340573.
    View in: PubMed Mentions: 117 Fields:
    Translation:HumansAnimals
  21. The Biology of Physiological Health. Cell. 2020 04 16; 181(2):250-269. Ayres JS. PMID: 32302569; PMCID: PMC7409982.
    View in: PubMed Mentions: 49 Fields:
    Translation:Humans
  22. Immunometabolism of infections. Nat Rev Immunol. 2020 02; 20(2):79-80. Ayres JS. PMID: 31892735.
    View in: PubMed Mentions: 49 Fields:
    Translation:HumansAnimalsCells
  23. Metabolic Adaptations to Infections at the Organismal Level. Trends Immunol. 2020 02; 41(2):113-125. Troha K, Ayres JS. PMID: 31959515; PMCID: PMC7409656.
    View in: PubMed Mentions: 47 Fields:
    Translation:Humans
  24. Host-Pathogen Relationship Advice: Fat Protects against a Broken Heart. Cell Metab. 2019 09 03; 30(3):409-411. McCarville JL, Ayres JS. PMID: 31484052.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  25. Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. Nat Chem Biol. 2018 11; 14(11):1021-1031. Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, Loomba R, Metallo CM. PMID: 30327559; PMCID: PMC6245668.
    View in: PubMed Mentions: 100 Fields:
    Translation:AnimalsCells
  26. Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen. Cell. 2018 09 20; 175(1):146-158.e15. Sanchez KK, Chen GY, Schieber AMP, Redford SE, Shokhirev MN, Leblanc M, Lee YM, Ayres JS. PMID: 30100182; PMCID: PMC6447043.
    View in: PubMed Mentions: 70 Fields:
    Translation:AnimalsCells
  27. When the Gut Gets Tough, the Enterocytes Get Going. Immunity. 2018 05 15; 48(5):837-839. Chen GY, Ayres JS. PMID: 29768167.
    View in: PubMed Mentions: Fields:
    Translation:AnimalsCells
  28. Decoding the intestinal epithelium cell by cell. Nat Immunol. 2018 01; 19(1):7-9. Lee YM, Ayres JS. PMID: 29242547.
    View in: PubMed Mentions: 2 Fields:
  29. Disease tolerance: concept and mechanisms. Curr Opin Immunol. 2018 02; 50:88-93. McCarville JL, Ayres JS. PMID: 29253642; PMCID: PMC5884632.
    View in: PubMed Mentions: 80 Fields:
    Translation:HumansAnimalsCells
  30. Resistance and tolerance defenses in cancer: Lessons from infectious diseases. Semin Immunol. 2017 08; 32:54-61. Rao S, Ayres JS. PMID: 28865876.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansAnimals
  31. NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. Immunity. 2017 04 18; 46(4):649-659. Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE. PMID: 28410991; PMCID: PMC5476318.
    View in: PubMed Mentions: 251 Fields:
    Translation:AnimalsCells
  32. Pathogen-Mediated Inhibition of Anorexia Promotes Host Survival and Transmission. Cell. 2017 01 26; 168(3):503-516.e12. Rao S, Schieber AMP, O'Connor CP, Leblanc M, Michel D, Ayres JS. PMID: 28129542; PMCID: PMC5324724.
    View in: PubMed Mentions: 81 Fields:
    Translation:HumansAnimalsCells
  33. Microbes Dress for Success: Tolerance or Resistance? Trends Microbiol. 2017 01; 25(1):1-3. Ayres JS. PMID: 27894645.
    View in: PubMed Mentions: 5 Fields:
    Translation:HumansAnimalsCells
  34. Thermoregulation as a disease tolerance defense strategy. Pathog Dis. 2016 12; 74(9). Schieber AM, Ayres JS. PMID: 27815313; PMCID: PMC5975229.
    View in: PubMed Mentions: 29 Fields:
    Translation:HumansAnimals
  35. Disease Tolerance Trick or Treat: Give Your Brain Something Good to Eat. Cell. 2016 Sep 08; 166(6):1368-1370. Ayres JS. PMID: 27610563.
    View in: PubMed Mentions: 2 Fields:
    Translation:Humans
  36. Cooperative Microbial Tolerance Behaviors in Host-Microbiota Mutualism. Cell. 2016 Jun 02; 165(6):1323-1331. Ayres JS. PMID: 27259146; PMCID: PMC4903080.
    View in: PubMed Mentions: 58 Fields:
    Translation:HumansAnimals
  37. Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance. Proc Natl Acad Sci U S A. 2016 Jun 07; 113(23):E3307-14. Shen R, Wang B, Giribaldi MG, Ayres J, Thomas JB, Montminy M. PMID: 27208092; PMCID: PMC4988575.
    View in: PubMed Mentions: 21 Fields:
    Translation:AnimalsCells
  38. Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling. Science. 2015 Oct 30; 350(6260):558-63. Schieber AM, Lee YM, Chang MW, Leblanc M, Collins B, Downes M, Evans RM, Ayres JS. PMID: 26516283; PMCID: PMC4732872.
    View in: PubMed Mentions: 101 Fields:
    Translation:AnimalsCells
  39. Inflammasome-microbiota interplay in host physiologies. Cell Host Microbe. 2013 Nov 13; 14(5):491-7. Ayres JS. PMID: 24237695.
    View in: PubMed Mentions: 25 Fields:
    Translation:HumansAnimals
  40. The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature. 2013 Sep 26; 501(7468):512-6. Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS. PMID: 24005326; PMCID: PMC3886920.
    View in: PubMed Mentions: 347 Fields:
    Translation:AnimalsCells
  41. Recognition of bacteria by inflammasomes. Annu Rev Immunol. 2013; 31:73-106. von Moltke J, Ayres JS, Kofoed EM, Chavarría-Smith J, Vance RE. PMID: 23215645.
    View in: PubMed Mentions: 223 Fields:
    Translation:HumansAnimalsCells
  42. Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota. Nat Med. 2012 May; 18(5):799-806. Ayres JS, Trinidad NJ, Vance RE. PMID: 22522562; PMCID: PMC3472005.
    View in: PubMed Mentions: 125 Fields:
    Translation:AnimalsCells
  43. Cellular teamwork in antibacterial innate immunity. Nat Immunol. 2012 Jan 19; 13(2):115-7. Ayres JS, Vance RE. PMID: 22261960.
    View in: PubMed Mentions: 3 Fields:
    Translation:AnimalsCells
  44. The circadian clock protein timeless regulates phagocytosis of bacteria in Drosophila. PLoS Pathog. 2012 Jan; 8(1):e1002445. Stone EF, Fulton BO, Ayres JS, Pham LN, Ziauddin J, Shirasu-Hiza MM. PMID: 22253593; PMCID: PMC3257305.
    View in: PubMed Mentions: 65 Fields:
    Translation:AnimalsCells
  45. Tolerance of infections. Annu Rev Immunol. 2012; 30:271-94. Ayres JS, Schneider DS. PMID: 22224770.
    View in: PubMed Mentions: 238 Fields:
    Translation:HumansAnimals
  46. The role of anorexia in resistance and tolerance to infections in Drosophila. PLoS Biol. 2009 Jul; 7(7):e1000150. Ayres JS, Schneider DS. PMID: 19597539; PMCID: PMC2701602.
    View in: PubMed Mentions: 156 Fields:
    Translation:AnimalsCells
  47. A signaling protease required for melanization in Drosophila affects resistance and tolerance of infections. PLoS Biol. 2008 Dec 09; 6(12):2764-73. Ayres JS, Schneider DS. PMID: 19071960; PMCID: PMC2596860.
    View in: PubMed Mentions: 122 Fields:
    Translation:AnimalsCells
  48. Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases. Nat Rev Immunol. 2008 11; 8(11):889-95. Schneider DS, Ayres JS. PMID: 18927577; PMCID: PMC4368196.
    View in: PubMed Mentions: 409 Fields:
    Translation:HumansAnimals
  49. Pathogenesis of listeria-infected Drosophila wntD mutants is associated with elevated levels of the novel immunity gene edin. PLoS Pathog. 2008 Jul 25; 4(7):e1000111. Gordon MD, Ayres JS, Schneider DS, Nusse R. PMID: 18654628; PMCID: PMC2453329.
    View in: PubMed Mentions: 16 Fields:
    Translation:AnimalsCells
  50. Identification of Drosophila mutants altering defense of and endurance to Listeria monocytogenes infection. Genetics. 2008 Mar; 178(3):1807-15. Ayres JS, Freitag N, Schneider DS. PMID: 18245331; PMCID: PMC2278058.
    View in: PubMed Mentions: 84 Fields:
    Translation:AnimalsCells
  51. Interactions between circadian rhythm and immunity in Drosophila melanogaster. Curr Biol. 2007 May 15; 17(10):R353-5. Shirasu-Hiza MM, Dionne MS, Pham LN, Ayres JS, Schneider DS. PMID: 17502084.
    View in: PubMed Mentions: 64 Fields:
    Translation:AnimalsCells
  52. Drosophila eiger mutants are sensitive to extracellular pathogens. PLoS Pathog. 2007 Mar; 3(3):e41. Schneider DS, Ayres JS, Brandt SM, Costa A, Dionne MS, Gordon MD, Mabery EM, Moule MG, Pham LN, Shirasu-Hiza MM. PMID: 17381241; PMCID: PMC1829408.
    View in: PubMed Mentions: 62 Fields:
    Translation:AnimalsCells
  53. Genomic dissection of microbial pathogenesis in cultured Drosophila cells. Trends Microbiol. 2006 Mar; 14(3):101-4. Ayres JS, Schneider DS. PMID: 16473012.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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