Palmer Taylor • UCSD Profiles (original) (raw)

  1. The ionizing zwitterionic oxime antidote attenuates gliosis in mice exposed to sarin. Chem Biol Interact. 2025 Nov 01; 421:111767. Macek Hrvat N, Puljko B, Sit RK, Ilic K, Kolic D, Mlinac-Jerkovic K, Kalanj-Bognar S, Radic Z, Sharpless BK, Taylor P, Kovarik Z. PMID: 41038430.
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    Translation:AnimalsCells
  2. Enhancing Target Tissue Levels and Diminishing Plasma Clearance of Ionizing Zwitterionic Antidotes in Organophosphate Exposures. J Pharmacol Exp Ther. 2021 Sep; 378(3):315-321. Shyong YJ, Sepulveda Y, Garcia A, Samskey NM, Radic Z, Sit RK, Sharpless KB, Momper JD, Taylor P. PMID: 34145064; PMCID: PMC11046989.
    View in: PubMed Mentions: 1 Fields:
    Translation:Animals
  3. Cholinergic Capsules and Academic Admonitions. Annu Rev Pharmacol Toxicol. 2021 01 06; 61:25-46. Taylor P. PMID: 33411578.
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    Translation:Humans
  4. Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[18 F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [18 F]-VXS. Ann N Y Acad Sci. 2020 11; 1479(1):180-195. Hayes TR, Blecha JE, Chao CK, Huynh TL, VanBrocklin HF, Zinn KR, Taylor PW, Gerdes JM, Thompson CM. PMID: 32436233; PMCID: PMC7677195.
    View in: PubMed Mentions: 1 Fields:
    Translation:Animals
  5. Lessons from nature: Structural studies and drug design driven by a homologous surrogate from invertebrates, AChBP. Neuropharmacology. 2020 11 15; 179:108108. Camacho-Hernandez GA, Taylor P. PMID: 32353365.
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    Translation:HumansAnimalsCells
  6. Adhesion, Catalysis and Signaling: A Commonality of Association Followed by Distinctive Events Driving Function. Structure. 2019 07 02; 27(7):1055-1056. Taylor P. PMID: 31269459.
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    Translation:Cells
  7. Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure. Chem Biol Interact. 2019 Aug 01; 308:194-197. Taylor P, Yan-Jye S, Momper J, Hou W, Camacho-Hernandez GA, Radic' Z, Rosenberg Y, Kovarik Z, Sit R, Sharpless KB. PMID: 31100277.
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    Translation:HumansAnimals
  8. Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase. Toxicol Appl Pharmacol. 2019 06 01; 372:40-46. Kovarik Z, Macek Hrvat N, Kalisiak J, Katalinic M, Sit RK, Zorbaz T, Radic Z, Fokin VV, Sharpless KB, Taylor P. PMID: 30978400.
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    Translation:HumansCells
  9. Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure. J Pharmacol Exp Ther. 2018 11; 367(2):363-372. Sit RK, Kovarik Z, Macek Hrvat N, Žunec S, Green C, Fokin VV, Sharpless KB, Radic Z, Taylor P. PMID: 30190337; PMCID: PMC6223194.
    View in: PubMed Mentions: 17 Fields:
    Translation:Animals
  10. Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques. Toxicol Lett. 2018 Sep 01; 293:229-234. Rosenberg YJ, Wang J, Ooms T, Rajendran N, Mao L, Jiang X, Lees J, Urban L, Momper JD, Sepulveda Y, Shyong YJ, Taylor P. PMID: 29129799; PMCID: PMC5943181.
    View in: PubMed Mentions: 15 Fields:
    Translation:AnimalsPHPublic Health
  11. Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor. Chem Biol Interact. 2017 Aug 25; 274:50-57. Rosenberg YJ, Mao L, Jiang X, Lees J, Zhang L, Radic Z, Taylor P. PMID: 28693885; PMCID: PMC5586507.
    View in: PubMed Mentions: 20 Fields:
    Translation:Animals
  12. Planarian cholinesterase: in vitro characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity and reactivation. Arch Toxicol. 2017 Aug; 91(8):2837-2847. Hagstrom D, Hirokawa H, Zhang L, Radic Z, Taylor P, Collins ES. PMID: 27990564; PMCID: PMC6485937.
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    Translation:HumansAnimals
  13. Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein. Proc Natl Acad Sci U S A. 2014 Jul 22; 111(29):10749-54. Kaczanowska K, Harel M, Radic Z, Changeux JP, Finn MG, Taylor P. PMID: 25006260; PMCID: PMC4115551.
    View in: PubMed Mentions: 8 Fields:
    Translation:AnimalsCells
  14. Cholinesterase confabs and cousins: approaching forty years. Chem Biol Interact. 2013 Mar 25; 203(1):10-3. Taylor P, De Jaco A, Comoletti D, Miller M, Camp S. PMID: 23085121; PMCID: PMC3618580.
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    Translation:HumansAnimalsCells
  15. Creating an α7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein: crystallographic and ligand selectivity analyses. J Biol Chem. 2011 Dec 09; 286(49):42555-42565. Nemecz Á, Taylor P. PMID: 22009746; PMCID: PMC3234955.
    View in: PubMed Mentions: 30 Fields:
    Translation:HumansCells
  16. Defining the determinants of nicotine selectivity. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13195-6. Taylor P. PMID: 20643924; PMCID: PMC2922162.
    View in: PubMed Mentions: 1 Fields:
    Translation:AnimalsCells
  17. From Split to Sibenik: the tortuous pathway in the cholinesterase field. Chem Biol Interact. 2010 Sep 06; 187(1-3):3-9. Taylor P. PMID: 20493179; PMCID: PMC3000743.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansAnimals
  18. Virtual screening against alpha-cobratoxin. J Biomol Screen. 2009 Oct; 14(9):1109-18. Utsintong M, Talley TT, Taylor PW, Olson AJ, Vajragupta O. PMID: 19734437; PMCID: PMC3191909.
    View in: PubMed Mentions: 8 Fields:
    Translation:HumansAnimalsCells
  19. Application of recombinant DNA methods for production of cholinesterases as organophosphate antidotes and detectors. Arh Hig Rada Toksikol. 2007 Sep; 58(3):339-45. Taylor P, Reiner E, Kovarik Z, Radic Z. PMID: 17913689.
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  20. Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes. Biochem Pharmacol. 2007 Oct 15; 74(8):1164-71. Taylor P, Talley TT, Radic' Z, Hansen SB, Hibbs RE, Shi J. PMID: 17826748; PMCID: PMC3341175.
    View in: PubMed Mentions: 19 Fields:
    Translation:HumansAnimalsCells
  21. Acetylcholinesterase: converting a vulnerable target to a template for antidotes and detection of inhibitor exposure. Toxicology. 2007 Apr 20; 233(1-3):70-8. Taylor P, Kovarik Z, Reiner E, Radic Z. PMID: 17196318; PMCID: PMC3279330.
    View in: PubMed Mentions: 9 Fields:
    Translation:HumansCells
  22. Contemporary paradigms for cholinergic ligand design guided by biological structure. Bioorg Med Chem Lett. 2004 Apr 19; 14(8):1875-7. Taylor P, Hansen SB, Talley TT, Hibbs RE, Radic Z. PMID: 15050619; PMCID: PMC3191913.
    View in: PubMed Mentions: 1 Fields:
    Translation:Cells

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This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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