Pradipta Ghosh • UCSD Profiles (original) (raw)
- A Druggable G Protein Checkpoint in Cholesterol Efflux. bioRxiv. 2026 Feb 17. Katkar GD, Anandachar MS, Espinoza CR, Estanol M, Biggs C, Nacayama M, Tam E, Mukharjee R, McLaren E, Aviles S, Castillo V, Mullick M, Yang J, Kaufmann B, Sinha S, Ghosh P. PMID: 41757070; PMCID: PMC12934564.
View in: PubMed Mentions: - New approach methodologies in Crohn's disease link molecular disease subtypes to clinical outcomes. Am J Physiol Gastrointest Liver Physiol. 2026 Mar 01; 330(3):G322-G329. Penrose HM, Sinha S, Tindle C, Zablan K, Le HN, Neill J, Ghosh P, Boland BS. PMID: 41665110.
View in: PubMed Mentions: - COMPASS: A Web-Based COMPosite Activity Scoring System to Navigate Health and Disease Through Deterministic Digital Biomarkers. bioRxiv. 2026 Feb 09. Sinha S, Ghosh P. PMID: 41573865; PMCID: PMC12822815.
View in: PubMed Mentions: - CANDiT: A machine learning framework for differentiation therapy in colorectal cancer. Cell Rep Med. 2025 Nov 18; 6(11):102421. Sinha S, Alcantara J, Perry K, Castillo V, Ondersma AK, Banerjee S, McLaren E, Espinoza CR, Taheri S, Vidales E, Tindle C, Adel A, Amirfakhri S, Sawires JR, Yang J, Bouvet M, Ghosh P. PMID: 41118768; PMCID: PMC12711679.
View in: PubMed Mentions: Fields:
Translation:HumansAnimalsCells - Distinct colitis-associated macrophages drive NOD2-dependent bacterial sensing and gut homeostasis. J Clin Invest. 2025 Dec 01; 135(23). Katkar GD, Anandachar MS, Ibeawuchi SC, McLaren EG, Estanol ML, Carpio-Perkins K, Hsu ST, Espinoza CR, Coates JE, Malhotra YS, Mullick M, Castillo V, Vo D, Sinha S, Ghosh P. PMID: 41321314; PMCID: PMC12646664.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimalsCells - Nootropic benzothiazoles promote dendritic spine formation by targeting fascin-1. J Biol Chem. 2025 09; 301(9):110572. Shivkumar A, Berg KR, Sibucao KC, Leriche G, Dozier LE, Espinoza CA, Patrick GN, Gaieb Z, Seitz C, Amaro RE, Park HH, Hoe HS, Wozniak J, Gonzalez DJ, Sinha S, Ghosh P, Yang J. PMID: 40784448; PMCID: PMC12926044.
View in: PubMed Mentions: Fields: - Distinct Colitis-Associated Macrophages Drive NOD2-Dependent Bacterial Sensing and Gut Homeostasis. bioRxiv. 2025 Jul 31. Katkar GD, Anandachar MS, Ibeawuchi SR, McLaren E, Estanol M, Carpio-Perkins K, Hsu ST, Espinoza CR, Coates J, Malhotra YS, Mullick M, Castillo V, Vo DT, Sinha S, Ghosh P. PMID: 40766554; PMCID: PMC12324400.
View in: PubMed Mentions: - A Living Organoid Biobank of Crohn's Disease Patients Reveals Distinct Clinical Correlates of Molecular Disease Subtypes. medRxiv. 2025 Jul 09. Penrose HM, Sinha S, Tindle C, Zablan K, Le HN, Neill J, Ghosh P, Boland BS. PMID: 40236416; PMCID: PMC11998810.
View in: PubMed Mentions: - Machine Learning-Guided Differentiation Therapy Targets Cancer Stem Cells in Colorectal Cancers. bioRxiv. 2025 Jul 09. Sinha S, Alcantara J, Perry K, Castillo V, Ondersma A, Banerjee S, McLaren E, Espinoza CR, Taheri S, Vidales E, Tindle C, Adel A, Amirfakhri S, Sawires JR, Yang J, Bouvet M, Ghosh P. PMID: 37745574; PMCID: PMC10515918.
View in: PubMed Mentions: - F.O.R.W.A.R.D: A Data-Driven Framework for Network-Based Target Prioritization in Drug Discovery. bioRxiv. 2025 Apr 30. Sinha S, McLaren E, Mullick M, Penrose HM, Tindle C, Singh S, Boland BS, Ghosh P. PMID: 39071297; PMCID: PMC11275938.
View in: PubMed Mentions: - A new locoregional mouse model of gastric cancer for identifying probes for fluorescence guided surgery. Surgery. 2025 05; 181:109270. Cox KE, Amirfakhri S, Lwin TM, Hosseini M, Ghosh P, Obonyo M, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 40043513.
View in: PubMed Mentions: 2 Fields:
Translation:HumansAnimalsCells - The waning of the WIMP: endgame? Eur Phys J C Part Fields. 2025; 85(2):152. Arcadi G, Cabo-Almeida D, Dutra M, Ghosh P, Lindner M, Mambrini Y, Neto JP, Pierre M, Profumo S, Queiroz FS. PMID: 40206215; PMCID: PMC11976390.
View in: PubMed Mentions: - Bright and Specific Targeting of Metastatic Lymph Nodes in Orthotopic Mouse Models of Gastric Cancer with a Fluorescent Anti-CEA Antibody. Ann Surg Oncol. 2025 May; 32(5):3796-3803. Cox KE, Amirfakhri S, Lwin TM, Hosseini M, Ghosh P, Obonyo M, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 39878844.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimalsCells - Differential Efficacy of Advanced Therapies in Inducing Remission in Ulcerative Colitis Based on Prior Exposure to TNF Antagonists. Clin Gastroenterol Hepatol. 2025 Nov; 23(12):2102-2114.e5. Lee HH, Solitano V, Singh S, Ananthakrishnan AN, Jairath V, Syal G, Boland BS, Ghosh P, Chang JT, Singh S. PMID: 39732355; PMCID: PMC12209402.
View in: PubMed Mentions: 11 Fields:
Translation:Humans - Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels. J Clin Invest. 2024 Oct 31; 134(24). Sinha S, Callow BW, Farfel AP, Roy S, Chen S, Masotti M, Rajendran S, Buschhaus JM, Espinoza CR, Luker KE, Ghosh P, Luker GD. PMID: 39480488; PMCID: PMC11645149.
View in: PubMed Mentions: 8 Fields:
Translation:HumansAnimalsCells - A living organoid biobank of patients with Crohn's disease reveals molecular subtypes for personalized therapeutics. Cell Rep Med. 2024 Oct 15; 5(10):101748. Tindle C, Fonseca AG, Taheri S, Katkar GD, Lee J, Maity P, Sayed IM, Ibeawuchi SR, Vidales E, Pranadinata RF, Fuller M, Stec DL, Anandachar MS, Perry K, Le HN, Ear J, Boland BS, Sandborn WJ, Sahoo D, Das S, Ghosh P. PMID: 39332415; PMCID: PMC11513829.
View in: PubMed Mentions: 6 Fields:
Translation:HumansCells - Breast Cancers That Disseminate to Bone Marrow Acquire Aggressive Phenotypes through CX43-related Tumor-Stroma Tunnels. bioRxiv. 2024 Aug 10. Sinha S, Callow BW, Farfel AP, Roy S, Chen S, Rajendran S, Buschhaus JM, Espinoza CR, Luker KE, Ghosh P, Luker GD. PMID: 36993616; PMCID: PMC10055300.
View in: PubMed Mentions: - A treadmill training program in a gamified virtual reality environment combined with transcranial direct current stimulation in Parkinson's Disease: Study protocol for a randomized controlled trial. PLoS One. 2024; 19(7):e0307304. Bosch-Barceló P, Climent-Sanz C, Martínez-Navarro O, Masbernat-Almenara M, Pakarinen A, Ghosh PK, Fernández-Lago H. PMID: 39012877; PMCID: PMC11251630.
View in: PubMed Mentions: 5 Fields:
Translation:HumansCTClinical Trials - Human-specific elimination of epithelial Siglec-XII suppresses the risk of inflammation-driven colorectal cancers. JCI Insight. 2024 Jul 11; 9(16). Cuello HA, Sinha S, Verhagen AL, Varki N, Varki A, Ghosh P. PMID: 38990656; PMCID: PMC11343606.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimals - Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody. Ann Surg Oncol. 2024 Sep; 31(9):6291-6299. Cox KE, Turner MA, Lwin TM, Amirfakhri S, Kelly KJ, Hosseini M, Ghosh P, Obonyo M, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 38888861; PMCID: PMC11300635.
View in: PubMed Mentions: 3 Fields:
Translation:HumansAnimalsCells - Growth factor-dependent phosphorylation of Gαi shapes canonical signaling by G protein-coupled receptors. Sci Signal. 2024 06 04; 17(839):eade8041. Roy S, Sinha S, Silas AJ, Ghassemian M, Kufareva I, Ghosh P. PMID: 38833528; PMCID: PMC11328959.
View in: PubMed Mentions: 3 Fields:
Translation:HumansAnimalsCells - Molecular Signatures for Microbe-Associated Colorectal Cancers. bioRxiv. 2024 May 27. Sayed IM, Vo DT, Alcantara J, Inouye KM, Pranadinata RF, Luo L, Boland CR, Goyal NP, Kuo DJ, Huang SC, Sahoo D, Ghosh P, Das S. PMID: 38853996; PMCID: PMC11160670.
View in: PubMed Mentions: 2 - MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic (MIP-C). EBioMedicine. 2024 Jun; 104:105136. David P, Sinha S, Iqbal K, De Marco G, Taheri S, McLaren E, Maisuria S, Arumugakani G, Ash Z, Buckley C, Coles L, Hettiarachchi C, Payne E, Savic S, Smithson G, Slade M, Shah R, Marzo-Ortega H, Keen M, Lawson C, Mclorinan J, Nizam S, Reddy H, Sharif O, Sultan S, Tran G, Wood M, Wood S, Ghosh P, McGonagle D. PMID: 38723554; PMCID: PMC11090026.
View in: PubMed Mentions: 18 Fields:
Translation:HumansCellsPHPublic Health - Engineered bacterial therapeutics for detecting and treating CRC. Trends Cancer. 2024 07; 10(7):588-597. Siguenza N, Brevi A, Zhang JT, Pabani A, Bhushan A, Das M, Ding Y, Hasty J, Ghosh P, Zarrinpar A. PMID: 38693003; PMCID: PMC11392429.
View in: PubMed Mentions: 3 Fields:
Translation:HumansAnimalsCells - Interlinked switch circuits of biological intelligence. Trends Biochem Sci. 2024 04; 49(4):286-289. Mukherjee R, Sinha S, Luker GD, Ghosh P. PMID: 38341333.
View in: PubMed Mentions: Fields:
Translation:Cells - Growth signaling autonomy in circulating tumor cells aids metastatic seeding. PNAS Nexus. 2024 Feb; 3(2):pgae014. Sinha S, Farfel A, Luker KE, Parker BA, Yeung KT, Luker GD, Ghosh P. PMID: 38312224; PMCID: PMC10833458.
View in: PubMed Mentions: 3 - The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection. Nat Commun. 2023 12 09; 14(1):8169. Tapryal N, Chakraborty A, Saha K, Islam A, Pan L, Hosoki K, Sayed IM, Duran JM, Alcantara J, Castillo V, Tindle C, Sarker AH, Wakamiya M, Cardenas VJ, Sharma G, Crotty Alexander LE, Sur S, Sahoo D, Ghosh G, Das S, Ghosh P, Boldogh I, Hazra TK. PMID: 38071370; PMCID: PMC10710473.
View in: PubMed Mentions: 6 Fields:
Translation:HumansAnimalsCells - Macrophage states: there's a method in the madness. Trends Immunol. 2023 12; 44(12):954-964. Katkar G, Ghosh P. PMID: 37945504; PMCID: PMC11266835.
View in: PubMed Mentions: 17 Fields:
Translation:HumansCells - MDA5-autoimmunity and Interstitial Pneumonitis Contemporaneous with the COVID-19 Pandemic (MIP-C). medRxiv. 2023 Nov 05. Iqbal K, Sinha S, David P, De Marco G, Taheri S, McLaren E, Maisuria S, Arumugakani G, Ash Z, Buckley C, Coles L, Hettiarachchi C, Smithson G, Slade M, Shah R, Marzo-Ortega H, Keen M, Lawson C, Mclorinan J, Nizam S, Reddy H, Sharif O, Sultan S, Tran G, Wood M, Wood S, Ghosh P, McGonagle D. PMID: 37961408; PMCID: PMC10635254.
View in: PubMed Mentions: - Diverse gut pathogens exploit the host engulfment pathway via a conserved mechanism. J Biol Chem. 2023 12; 299(12):105390. Anandachar MS, Roy S, Sinha S, Boadi A, Katkar GD, Ghosh P. PMID: 37890785; PMCID: PMC10696401.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimalsCells - Humanized Anti-Carcinoembryonic Antigen Antibodies Brightly Target and Label Gastric Cancer in Orthotopic Mouse Models. J Surg Res. 2024 01; 293:701-708. Cox KE, Turner MA, Amirfakhri S, Lwin TM, Hosseini M, Ghosh P, Obonyo M, Murakami T, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 37839102; PMCID: PMC11060874.
View in: PubMed Mentions: 5 Fields:
Translation:HumansAnimalsCells - Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects. J Clin Invest. 2023 10 02; 133(19). Saul S, Karim M, Ghita L, Huang PT, Chiu W, Durán V, Lo CW, Kumar S, Bhalla N, Leyssen P, Alem F, Boghdeh NA, Tran DH, Cohen CA, Brown JA, Huie KE, Tindle C, Sibai M, Ye C, Khalil AM, Chiem K, Martinez-Sobrido L, Dye JM, Pinsky BA, Ghosh P, Das S, Solow-Cordero DE, Jin J, Wikswo JP, Jochmans D, Neyts J, De Jonghe S, Narayanan A, Einav S. PMID: 37581931; PMCID: PMC10541190.
View in: PubMed Mentions: 10 Fields:
Translation:HumansAnimalsCells - The arginine methyltransferase PRMT5 promotes mucosal defense in the intestine. Life Sci Alliance. 2023 11; 6(11). Hernandez JE, Llorente C, Ma S, Miyamoto KT, Sinha S, Steele S, Xiao Z, Lai CJ, Zuniga EI, Ghosh P, Schnabl B, Huang WJM. PMID: 37666668; PMCID: PMC10477432.
View in: PubMed Mentions: 3 Fields:
Translation:Animals - Diverse Gut Pathogens Exploit the Host Engulfment Pathway via a Conserved Mechanism. bioRxiv. 2023 Aug 27. Anandachar MS, Roy S, Sinha S, Agyekum B, Ibeawuchi SR, Gementera H, Amamoto A, Katkar GD, Ghosh P. PMID: 37066267; PMCID: PMC10104235.
View in: PubMed Mentions: - Bicyclic Peptide Library Screening for the Identification of Gαi Protein Modulators. J Med Chem. 2023 09 14; 66(17):12396-12406. Pepanian A, Binbay FA, Roy S, Nubbemeyer B, Koley A, Rhodes CA, Ammer H, Pei D, Ghosh P, Imhof D. PMID: 37587416; PMCID: PMC11000586.
View in: PubMed Mentions: 2 Fields:
Translation:Cells - Clinicopathologic Significance of Heat Shock Protein 60 as a Survival Predictor in Colorectal Cancer. Cancers (Basel). 2023 Aug 11; 15(16). Kang M, Jeong S, An J, Park S, Nam S, Kwon KA, Sahoo D, Ghosh P, Kim JH. PMID: 37627080; PMCID: PMC10452225.
View in: PubMed Mentions: 7 - Machine learning identifies signatures of macrophage reactivity and tolerance that predict disease outcomes. EBioMedicine. 2023 Aug; 94:104719. Ghosh P, Sinha S, Katkar GD, Vo D, Taheri S, Dang D, Das S, Sahoo D. PMID: 37516087; PMCID: PMC10388732.
View in: PubMed Mentions: 17 Fields:
Translation:HumansAnimalsCells - Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects. bioRxiv. 2023 May 10. Saul S, Karim M, Ghita L, Huang PT, Chiu W, Durán V, Lo CW, Kumar S, Bhalla N, Leyssen P, Alem F, Boghdeh NA, Tran DH, Cohen CA, Brown JA, Huie KE, Tindle C, Sibai M, Ye C, Khalil AM, Martinez-Sobrido L, Dye JM, Pinsky BA, Ghosh P, Das S, Solow-Cordero DE, Jin J, Wikswo JP, Jochmans D, Neyts J, Jonghe S, Narayanan A, Einav S. PMID: 34159337; PMCID: PMC8219101.
View in: PubMed Mentions: 2 - Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer. Curr Issues Mol Biol. 2023 Apr 11; 45(4):3347-3358. Turner MA, Cox KE, Liu S, Neel N, Amirfakhri S, Nishino H, Hosseini M, Alcantara JA, Abd El-Hafeez AA, Lwin TM, Mallya K, Pisegna JR, Singh SK, Ghosh P, Hoffman RM, Batra SK, Bouvet M. PMID: 37185743; PMCID: PMC10136452.
View in: PubMed Mentions: Fields: - A Living Organoid Biobank of Crohn's Disease Patients Reveals Molecular Subtypes for Personalized Therapeutics. bioRxiv. 2023 Mar 13. Tindle C, Katkar GD, Fonseca AG, Taheri S, Lee J, Maity P, Sayed IM, Ibeawuchi SR, Vidales E, Pranadinata RF, Fuller M, Stec DL, Anandachar MS, Perry K, Le HN, Ear J, Boland BS, Sandborn WJ, Sahoo D, Das S, Ghosh P. PMID: 36993763; PMCID: PMC10054961.
View in: PubMed Mentions: - A circuit for secretion-coupled cellular autonomy in multicellular eukaryotic cells. Mol Syst Biol. 2023 04 12; 19(4):e11127. Qiao L, Sinha S, Abd El-Hafeez AA, Lo IC, Midde KK, Ngo T, Aznar N, Lopez-Sanchez I, Gupta V, Farquhar MG, Rangamani P, Ghosh P. PMID: 36856068; PMCID: PMC10090951.
View in: PubMed Mentions: 7 Fields:
Translation:Cells - Identification of a novel gene signature for neuroblastoma differentiation using a Boolean implication network. Genes Chromosomes Cancer. 2023 06; 62(6):313-331. Zage PE, Huo Y, Subramonian D, Le Clorennec C, Ghosh P, Sahoo D. PMID: 36680522; PMCID: PMC10257350.
View in: PubMed Mentions: 3 Fields:
Translation:HumansCells - Design principles of improving the dose-response alignment in coupled GTPase switches. NPJ Syst Biol Appl. 2023 01 31; 9(1):3. Qiao L, Ghosh P, Rangamani P. PMID: 36720885; PMCID: PMC9889403.
View in: PubMed Mentions: 4 Fields:
Translation:Cells - Artificial intelligence-guided discovery of gastric cancer continuum. Gastric Cancer. 2023 03; 26(2):286-297. Vo D, Ghosh P, Sahoo D. PMID: 36692601; PMCID: PMC9871434.
View in: PubMed Mentions: 2 Fields:
Translation:HumansAnimals - Regulation of DNA damage response by trimeric G-proteins. iScience. 2023 Feb 17; 26(2):105973. Abd El-Hafeez AA, Sun N, Chakraborty A, Ear J, Roy S, Chamarthi P, Rajapakse N, Das S, Luker KE, Hazra TK, Luker GD, Ghosh P. PMID: 36756378; PMCID: PMC9900518.
View in: PubMed Mentions: 6 - 2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights. J Enzyme Inhib Med Chem. 2022 Dec; 37(1):349-372. Elbadawi MM, Eldehna WM, Abd El-Hafeez AA, Somaa WR, Albohy A, Al-Rashood ST, Agama KK, Elkaeed EB, Ghosh P, Pommier Y, Abe M. PMID: 34923887; PMCID: PMC8725837.
View in: PubMed Mentions: 11 Fields:
Translation:HumansCells - New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization. J Enzyme Inhib Med Chem. 2022 Dec; 37(1):1346-1363. Mohammed HHH, Abd El-Hafeez AA, Ebeid K, Mekkawy AI, Abourehab MAS, Wafa EI, Alhaj-Suliman SO, Salem AK, Ghosh P, Abuo-Rahma GEA, Hayallah AM, Abbas SH. PMID: 35548854; PMCID: PMC9116245.
View in: PubMed Mentions: 24 Fields:
Translation:HumansCells - Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer. J Enzyme Inhib Med Chem. 2022 Dec; 37(1):2265-2282. Abdelsalam EA, Abd El-Hafeez AA, Eldehna WM, El Hassab MA, Marzouk HMM, Elaasser MM, Abou Taleb NA, Amin KM, Abdel-Aziz HA, Ghosh P, Hammad SF. PMID: 36000167; PMCID: PMC9415638.
View in: PubMed Mentions: 30 Fields:
Translation:HumansCells - AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas. JCI Insight. 2022 09 22; 7(18). Ghosh P, Campos VJ, Vo DT, Guccione C, Goheen-Holland V, Tindle C, Mazzini GS, He Y, Alexandrov LB, Lippman SM, Gurski RR, Das S, Yadlapati R, Curtius K, Sahoo D. PMID: 36134663; PMCID: PMC9675486.
View in: PubMed Mentions: 9 Fields:
Translation:Humans - Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer. Eur J Med Chem. 2022 Dec 05; 243:114704. Akl L, Abd El-Hafeez AA, Ibrahim TM, Salem R, Marzouk HMM, El-Domany RA, Ghosh P, Eldehna WM, Abou-Seri SM. PMID: 36095992.
View in: PubMed Mentions: 13 Fields:
Translation:HumansCells - Publisher Correction: An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease. Nat Commun. 2022 Aug 11; 13(1):4729. Ghosh P, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye JT, Pediatric Emergency Medicine Kawasaki Disease Research Group, Bocchini J, Das S, Burns JC, Sahoo D. PMID: 35953486; PMCID: PMC9372045.
View in: PubMed Mentions: Fields: - COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis. EBioMedicine. 2022 Aug; 82:104185. Sinha S, Castillo V, Espinoza CR, Tindle C, Fonseca AG, Dan JM, Katkar GD, Das S, Sahoo D, Ghosh P. PMID: 35870428; PMCID: PMC9297827.
View in: PubMed Mentions: 25 Fields:
Translation:HumansAnimalsCells - COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis. bioRxiv. 2022 Jul 18. Sinha S, Castillo V, Espinoza CR, Tindle C, Fonseca AG, Dan JM, Katkar GD, Das S, Sahoo D, Ghosh P. PMID: 34873597; PMCID: PMC8647648.
View in: PubMed Mentions: - Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer. Oncogene. 2022 07; 41(29):3705-3718. Buschhaus JM, Rajendran S, Humphries BA, Cutter AC, Muñiz AJ, Ciavattone NG, Buschhaus AM, Cañeque T, Nwosu ZC, Sahoo D, Bevoor AS, Shah YM, Lyssiotis CA, Ghosh P, Wicha MS, Rodriguez R, Luker GD. PMID: 35732800; PMCID: PMC9288981.
View in: PubMed Mentions: 17 Fields:
Translation:Cells - The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection. Res Sq. 2022 May 27. Hazra T, Tapryal N, Chakraborty A, Rayavara K, Wakamiya M, Islam A, Pan L, Hsu J, Tat V, Maruyama J, Hosoki K, Sayed I, Alcantara J, Castillo V, Tindle C, Sarker A, Cardenas V, Sharma G, Alexander LC, Sur S, Ghosh G, Paessler S, Sahoo D, Ghosh P, Das S, Boldogh I, Tseng CT. PMID: 35665009; PMCID: PMC9164514.
View in: PubMed Mentions: - An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease. Nat Commun. 2022 05 16; 13(1):2687. Ghosh P, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye JT, Pediatric Emergency Medicine Kawasaki Disease Research Group, Bocchini J, Das S, Burns JC, Sahoo D. PMID: 35577777; PMCID: PMC9110726.
View in: PubMed Mentions: 38 Fields:
Translation:HumansCellsPHPublic Health - The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients. Cell Mol Gastroenterol Hepatol. 2022; 14(1):35-53. Gonzalez CG, Mills RH, Kordahi MC, Carrillo-Terrazas M, Secaira-Morocho H, Widjaja CE, Tsai MS, Mittal Y, Yee BA, Vargas F, Weldon K, Gauglitz JM, Delaroque C, Sauceda C, Rossitto LA, Ackermann G, Humphrey G, Swafford AD, Siegel CA, Buckey JC, Raffals LE, Sadler C, Lindholm P, Fisch KM, Valaseck M, Suriawinata A, Yeo GW, Ghosh P, Chang JT, Chu H, Dorrestein P, Zhu Q, Chassaing B, Knight R, Gonzalez DJ, Dulai PS. PMID: 35378331; PMCID: PMC9117812.
View in: PubMed Mentions: 14 Fields:
Translation:HumansAnimals - Artificial intelligence-rationalized balanced PPARα/γ dual agonism resets dysregulated macrophage processes in inflammatory bowel disease. Commun Biol. 2022 03 14; 5(1):231. Katkar GD, Sayed IM, Anandachar MS, Castillo V, Vidales E, Toobian D, Usmani F, Sawires JR, Leriche G, Yang J, Sandborn WJ, Das S, Sahoo D, Ghosh P. PMID: 35288651; PMCID: PMC8921270.
View in: PubMed Mentions: 11 Translation:HumansAnimalsCells - Parsing the Role of PPARs in Macrophage Processes. Front Immunol. 2021; 12:783780. Toobian D, Ghosh P, Katkar GD. PMID: 35003101; PMCID: PMC8727354.
View in: PubMed Mentions: 56 Fields:
Translation:HumansAnimalsCells - RNA binding protein DDX5 directs tuft cell specification and function to regulate microbial repertoire and disease susceptibility in the intestine. Gut. 2022 09; 71(9):1790-1802. Long T, Abbasi N, Hernandez JE, Li Y, Sayed IM, Ma S, Iemolo A, Yee BA, Yeo GW, Telese F, Ghosh P, Das S, Huang WJM. PMID: 34853057; PMCID: PMC9156727.
View in: PubMed Mentions: 11 Fields:
Translation:Animals - Clinico-pathological relationship between androgen receptor and tumour infiltrating lymphocytes in triple negative breast cancer. Ecancermedicalscience. 2021; 15:1317. Elghazawy H, Bakkach J, Helal T, Aref AM, Kelany M, Abdallah LE, Abdelbakey FS, Ali D, Ali DZ, Ahmed MO, El-Hafeez AAA, Ghosh P, Alorabi MO. PMID: 35047068; PMCID: PMC8723750.
View in: PubMed Mentions: 3 - SPT6 loss permits the transdifferentiation of keratinocytes into an intestinal fate that resembles Barrett's metaplasia. iScience. 2021 Oct 22; 24(10):103121. Vo DT, Fuller MR, Tindle C, Anandachar MS, Das S, Sahoo D, Ghosh P. PMID: 34622168; PMCID: PMC8481972.
View in: PubMed Mentions: 4 - GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility. Elife. 2021 08 19; 10. Reynoso S, Castillo V, Katkar GD, Lopez-Sanchez I, Taheri S, Espinoza C, Rohena C, Sahoo D, Gagneux P, Ghosh P. PMID: 34409938; PMCID: PMC8376251.
View in: PubMed Mentions: 3 Fields:
Translation:HumansAnimalsCells - Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19. Elife. 2021 08 13; 10. Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar GD, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S. PMID: 34463615; PMCID: PMC8463074.
View in: PubMed Mentions: 84 Fields:
Translation:HumansCells - An AI-guided signature reveals the nature of the shared proximal pathways of host immune response in MIS-C and Kawasaki disease. bioRxiv. 2021 Aug 09. Sahoo D, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye J, Pediatric Emergency Medicine Kawasaki Disease Research Group, Bocchini J, Das S, Burns JC, Ghosh P. PMID: 33880476; PMCID: PMC8057241.
View in: PubMed Mentions: - FAK inhibitors as promising anticancer targets: present and future directions. Future Med Chem. 2021 09; 13(18):1559-1590. Mustafa M, Abd El-Hafeez AA, Abdelhafeez DA, Abdelhamid D, Mostafa YA, Ghosh P, Hayallah AM, A Abuo-Rahma GE. PMID: 34340532; PMCID: PMC8386514.
View in: PubMed Mentions: 9 Fields:
Translation:HumansCells - Functional assays with human patient-derived enteroid monolayers to assess the human gut barrier. STAR Protoc. 2021 09 17; 2(3):100680. Sayed IM, Tindle C, Fonseca AG, Ghosh P, Das S. PMID: 34337445; PMCID: PMC8313751.
View in: PubMed Mentions: 6 Fields:
Translation:Humans - Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease. Nat Commun. 2021 07 12; 12(1):4246. Sahoo D, Swanson L, Sayed IM, Katkar GD, Ibeawuchi SR, Mittal Y, Pranadinata RF, Tindle C, Fuller M, Stec DL, Chang JT, Sandborn WJ, Das S, Ghosh P. PMID: 34253728; PMCID: PMC8275683.
View in: PubMed Mentions: 39 Fields:
Translation:HumansAnimals - AI-guided discovery of the invariant host response to viral pandemics. EBioMedicine. 2021 Jun; 68:103390. Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Alexander LEC, Duran J, Crotty S, Dan JM, Das S, Ghosh P. PMID: 34127431; PMCID: PMC8193764.
View in: PubMed Mentions: 24 Fields:
Translation:HumansAnimalsPHPublic Health - Drug repurposing screens identify chemical entities for the development of COVID-19 interventions. Nat Commun. 2021 06 03; 12(1):3309. Bakowski MA, Beutler N, Wolff KC, Kirkpatrick MG, Chen E, Nguyen TH, Riva L, Shaabani N, Parren M, Ricketts J, Gupta AK, Pan K, Kuo P, Fuller M, Garcia E, Teijaro JR, Yang L, Sahoo D, Chi V, Huang E, Vargas N, Roberts AJ, Das S, Ghosh P, Woods AK, Joseph SB, Hull MV, Schultz PG, Burton DR, Chatterjee AK, McNamara CW, Rogers TF. PMID: 34083527; PMCID: PMC8175350.
View in: PubMed Mentions: 69 Fields:
Translation:HumansAnimalsCellsPHPublic Health - A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1,2,4-triazoles. Eur J Med Chem. 2021 Oct 15; 222:113569. Mustafa M, Abd El-Hafeez AA, Abdelhamid D, Katkar GD, Mostafa YA, Ghosh P, Hayallah AM, Abuo-Rahma GEA. PMID: 34111829; PMCID: PMC8818328.
View in: PubMed Mentions: 14 Fields:
Translation:HumansCells - Building unconventional G protein-coupled receptors, one block at a time. Trends Pharmacol Sci. 2021 07; 42(7):514-517. Ghosh P, Mullick M. PMID: 33985816; PMCID: PMC8779748.
View in: PubMed Mentions: 2 Fields:
Translation:Cells - Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides. Acta Physiol (Oxf). 2021 06; 232(2):e13655. Muntjewerff EM, Tang K, Lutter L, Christoffersson G, Nicolasen MJT, Gao H, Katkar GD, Das S, Ter Beest M, Ying W, Ghosh P, El Aidy S, Oldenburg B, van den Bogaart G, Mahata SK. PMID: 33783968; PMCID: PMC8341099.
View in: PubMed Mentions: 21 Fields:
Translation:HumansAnimalsCells - Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19. bioRxiv. 2021 May 05. Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar G, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S. PMID: 33106807; PMCID: PMC7587781.
View in: PubMed Mentions: - AI-guided discovery of the invariant host response to viral pandemics. bioRxiv. 2021 Apr 13. Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Alexander LEC, Duran J, Crotty S, Dan JM, Das S, Ghosh P. PMID: 32995790; PMCID: PMC7523116.
View in: PubMed Mentions: - Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin). Hypertension. 2021 05 05; 77(5):1670-1682. Ying W, Tang K, Avolio E, Schilling JM, Pasqua T, Liu MA, Cheng H, Gao H, Zhang J, Mahata S, Ko MS, Bandyopadhyay G, Das S, Roth DM, Sahoo D, Webster NJG, Sheikh F, Ghosh G, Patel HH, Ghosh P, van den Bogaart G, Mahata SK. PMID: 33826401; PMCID: PMC8116433.
View in: PubMed Mentions: 31 Fields:
Translation:AnimalsCells - Modeling colorectal cancers using multidimensional organoids. Adv Cancer Res. 2021; 151:345-383. Sayed IM, El-Hafeez AAA, Maity PP, Das S, Ghosh P. PMID: 34148617; PMCID: PMC8221168.
View in: PubMed Mentions: 8 Fields:
Translation:Humans - Prevalence of MMTV-Like env Sequences and Its Association with BRCA1/2 Genes Mutations Among Egyptian Breast Cancer Patients. Cancer Manag Res. 2021; 13:2835-2848. Loutfy SA, Abdallah ZF, Shaalan M, Moneer M, Karam A, Moneer MM, Sayed IM, Abd El-Hafeez AA, Ghosh P, Zekri AN. PMID: 33814932; PMCID: PMC8009344.
View in: PubMed Mentions: 7 - Discovery of antiproliferative and anti-FAK inhibitory activity of 1,2,4-triazole derivatives containing acetamido carboxylic acid skeleton. Bioorg Med Chem Lett. 2021 05 15; 40:127965. Mustafa M, Abuo-Rahma GEA, Abd El-Hafeez AA, Ahmed ER, Abdelhamid D, Ghosh P, Hayallah AM. PMID: 33744442; PMCID: PMC8459745.
View in: PubMed Mentions: 9 Fields:
Translation:HumansCells - A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding. J Biol Chem. 2021 Jan-Jun; 296:100493. Ear J, Abd El-Hafeez AA, Roy S, Ngo T, Rajapakse N, Choi J, Khandelwal S, Ghassemian M, McCaffrey L, Kufareva I, Sahoo D, Ghosh P. PMID: 33675748; PMCID: PMC8042451.
View in: PubMed Mentions: 4 Fields:
Translation:HumansAnimalsCells - Stability Analysis of a Signaling Circuit with Dual Species of GTPase Switches. Bull Math Biol. 2021 02 20; 83(4):34. Stolerman LM, Ghosh P, Rangamani P. PMID: 33609194; PMCID: PMC8378325.
View in: PubMed Mentions: 2 Fields:
Translation:AnimalsCells - SPT6 promotes epidermal differentiation and blockade of an intestinal-like phenotype through control of transcriptional elongation. Nat Commun. 2021 02 04; 12(1):784. Li J, Xu X, Tiwari M, Chen Y, Fuller M, Bansal V, Tamayo P, Das S, Ghosh P, Sen GL. PMID: 33542242; PMCID: PMC7862286.
View in: PubMed Mentions: 15 Fields:
Translation:HumansCells - Deletion of intestinal epithelial AMP-activated protein kinase alters distal colon permeability but not glucose homeostasis. Mol Metab. 2021 05; 47:101183. Olivier S, Pochard C, Diounou H, Castillo V, Divoux J, Alcantara J, Leclerc J, Guilmeau S, Huet C, Charifi W, Varin TV, Daniel N, Foretz M, Neunlist M, Salomon BL, Ghosh P, Marette A, Rolli-Derkinderen M, Viollet B. PMID: 33548500; PMCID: PMC7921883.
View in: PubMed Mentions: 15 Fields:
Translation:AnimalsCells - E-cigarettes compromise the gut barrier and trigger inflammation. iScience. 2021 Feb 19; 24(2):102035. Sharma A, Lee J, Fonseca AG, Moshensky A, Kothari T, Sayed IM, Ibeawuchi SR, Pranadinata RF, Ear J, Sahoo D, Crotty-Alexander LE, Ghosh P, Das S. PMID: 33537654; PMCID: PMC7841355.
View in: PubMed Mentions: 36 - The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker in colorectal cancer. Mol Cancer. 2020 11 05; 19(1):155. Shigeyasu K, Toden S, Ozawa T, Matsuyama T, Nagasaka T, Ishikawa T, Sahoo D, Ghosh P, Uetake H, Fujiwara T, Goel A. PMID: 33148262; PMCID: PMC7643275.
View in: PubMed Mentions: 53 Fields:
Translation:HumansCells - Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi. Proc Natl Acad Sci U S A. 2020 11 17; 117(46):28763-28774. Kalogriopoulos NA, Lopez-Sanchez I, Lin C, Ngo T, Midde KK, Roy S, Aznar N, Murray F, Garcia-Marcos M, Kufareva I, Ghassemian M, Ghosh P. PMID: 33139573; PMCID: PMC7682395.
View in: PubMed Mentions: 15 Fields:
Translation:HumansAnimalsCells - TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin. Proc Natl Acad Sci U S A. 2020 10 27; 117(43):26895-26906. Swanson L, Katkar GD, Tam J, Pranadinata RF, Chareddy Y, Coates J, Anandachar MS, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P. PMID: 33055214; PMCID: PMC7604444.
View in: PubMed Mentions: 49 Fields:
Translation:HumansAnimalsCells - The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Cells. 2020 08 28; 9(9). Sayed IM, Chakraborty A, Abd El-Hafeez AA, Sharma A, Sahan AZ, Huang WJM, Sahoo D, Ghosh P, Hazra TK, Das S. PMID: 32872214; PMCID: PMC7565382.
View in: PubMed Mentions: 39 Fields:
Translation:HumansAnimalsCells - DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis. Life Sci Alliance. 2020 10; 3(10). Abbasi N, Long T, Li Y, Yee BA, Cho BS, Hernandez JE, Ma E, Patel PR, Sahoo D, Sayed IM, Varki N, Das S, Ghosh P, Yeo GW, Huang WJM. PMID: 32817263; PMCID: PMC7441524.
View in: PubMed Mentions: 16 Fields:
Translation:AnimalsCells - Correction: DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi. J Biol Chem. 2020 Jun 26; 295(26):8867. Marivin A, Maziarz M, Zhao J, DiGiacomo V, Calvo IO, Mann EA, Ear J, Blanco-Canosa JB, Ross EM, Ghosh P, Garcia-Marcos M. PMID: 32591443; PMCID: PMC7324496.
View in: PubMed Mentions: Fields: - Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells. J Biol Chem. 2020 08 07; 295(32):11082-11098. Sayed IM, Sahan AZ, Venkova T, Chakraborty A, Mukhopadhyay D, Bimczok D, Beswick EJ, Reyes VE, Pinchuk I, Sahoo D, Ghosh P, Hazra TK, Das S. PMID: 32518160; PMCID: PMC7415988.
View in: PubMed Mentions: 43 Fields:
Translation:HumansAnimalsCells - GIV/Girdin and Exo70 Collaboratively Regulate the Mammalian Polarized Exocytic Machinery. iScience. 2020 Jul 24; 23(7):101246. Rohena C, Rajapakse N, Lo IC, Novick P, Sahoo D, Ghosh P. PMID: 32590327; PMCID: PMC7322189.
View in: PubMed Mentions: 2 - Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer. Breast Cancer Res. 2020 06 05; 22(1):60. Humphries BA, Cutter AC, Buschhaus JM, Chen YC, Qyli T, Palagama DSW, Eckley S, Robison TH, Bevoor A, Chiang B, Haley HR, Sahoo S, Spinosa PC, Neale DB, Boppisetti J, Sahoo D, Ghosh P, Lahann J, Ross BD, Yoon E, Luker KE, Luker GD. PMID: 32503622; PMCID: PMC7275541.
View in: PubMed Mentions: 53 Fields:
Translation:HumansAnimalsCells - GIV•Kindlin Interaction Is Required for Kindlin-Mediated Integrin Recognition and Activation. iScience. 2020 Jun 26; 23(6):101209. Rohena C, Kalogriopoulos N, Rajapakse N, Roy S, Lopez-Sanchez I, Ablack J, Sahoo D, Ghosh P. PMID: 32535026; PMCID: PMC7300163.
View in: PubMed Mentions: 7 - Regulating cellular cyclic adenosine monophosphate: "Sources," "sinks," and now, "tunable valves". Wiley Interdiscip Rev Syst Biol Med. 2020 09; 12(5):e1490. Getz M, Rangamani P, Ghosh P. PMID: 32323924; PMCID: PMC7581534.
View in: PubMed Mentions: 5 Fields:
Translation:HumansCells - Computational Approach to Identifying Universal Macrophage Biomarkers. Front Physiol. 2020; 11:275. Dang D, Taheri S, Das S, Ghosh P, Prince LS, Sahoo D. PMID: 32322218; PMCID: PMC7156600.
View in: PubMed Mentions: 23 - Host engulfment pathway controls inflammation in inflammatory bowel disease. FEBS J. 2020 09; 287(18):3967-3988. Sayed IM, Suarez K, Lim E, Singh S, Pereira M, Ibeawuchi SR, Katkar G, Dunkel Y, Mittal Y, Chattopadhyay R, Guma M, Boland BS, Dulai PS, Sandborn WJ, Ghosh P, Das S. PMID: 32003126; PMCID: PMC7390677.
View in: PubMed Mentions: 35 Fields:
Translation:HumansAnimalsCells - The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer. Life Sci Alliance. 2020 03; 3(3). Ghosh P, Swanson L, Sayed IM, Mittal Y, Lim BB, Ibeawuchi SR, Foretz M, Viollet B, Sahoo D, Das S. PMID: 32041849; PMCID: PMC7012149.
View in: PubMed Mentions: 20 Fields:
Translation:HumansAnimalsCells - Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. iScience. 2020 Feb 21; 23(2):100859. Ear J, Saklecha A, Rajapakse N, Choi J, Ghassemian M, Kufareva I, Ghosh P. PMID: 32058970; PMCID: PMC7005484.
View in: PubMed Mentions: 7 - DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi. J Biol Chem. 2020 02 21; 295(8):2270-2284. Marivin A, Maziarz M, Zhao J, DiGiacomo V, Olmos Calvo I, Mann EA, Ear J, Blanco-Canosa JB, Ross EM, Ghosh P, Garcia-Marcos M. PMID: 31949046; PMCID: PMC7039542.
View in: PubMed Mentions: 13 Fields:
Translation:HumansAnimalsCells - The Gα-interacting vesicle-associated protein interacts with and promotes cell surface localization of GRP78 during endoplasmic reticulum stress. FEBS Lett. 2020 03; 594(6):1088-1100. Limso C, Ngo JM, Nguyen P, Leal S, Husain A, Sahoo D, Ghosh P, Bhandari D. PMID: 31736058; PMCID: PMC7093220.
View in: PubMed Mentions: 7 Fields:
Translation:HumansAnimalsCells - Do All Roads Lead to Rome in G-Protein Activation? Trends Biochem Sci. 2020 03; 45(3):182-184. Ghosh P, Garcia-Marcos M. PMID: 31753703; PMCID: PMC7147754.
View in: PubMed Mentions: 8 Fields:
Translation:HumansCells - Metformin Is Associated With Reduced Odds for Colorectal Cancer Among Persons With Diabetes. Clin Transl Gastroenterol. 2019 11; 10(11):e00092. Demb J, Yaseyyedi A, Liu L, Bustamante R, Earles A, Ghosh P, Gutkind JS, Gawron AJ, Kaltenbach TR, Martinez ME, Gupta S. PMID: 31770138; PMCID: PMC6890275.
View in: PubMed Mentions: 6 Fields:
Translation:Humans - Novel candidates in early-onset familial colorectal cancer. Fam Cancer. 2020 01; 19(1):1-10. Jansen AML, Ghosh P, Dakal TC, Slavin TP, Boland CR, Goel A. PMID: 31555933; PMCID: PMC7241873.
View in: PubMed Mentions: 11 Fields:
Translation:Humans - Controversies about the subcellular localization and mechanisms of action of the Alzheimer's disease-protective CD33 splice variant. Acta Neuropathol. 2019 10; 138(4):671-672. Saha S, Siddiqui SS, Khan N, Verhagen A, Jiang W, Springer S, Ghosh P, Varki A. PMID: 31440824.
View in: PubMed Mentions: 5 Fields:
Translation:Humans - Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors. Sci Rep. 2019 08 20; 9(1):12124. Ear J, Dunkel Y, Mittal Y, Lim BBC, Liu L, Holda MK, Nitsche U, Barbazán J, Goel A, Janssen KP, Aznar N, Ghosh P. PMID: 31431650; PMCID: PMC6702192.
View in: PubMed Mentions: 9 Fields:
Translation:HumansAnimalsCells - Structural basis for GPCR-independent activation of heterotrimeric Gi proteins. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16394-16403. Kalogriopoulos NA, Rees SD, Ngo T, Kopcho NJ, Ilatovskiy AV, Sun N, Komives EA, Chang G, Ghosh P, Kufareva I. PMID: 31363053; PMCID: PMC6697900.
View in: PubMed Mentions: 24 Fields:
Translation:HumansCells - A predictive computational model reveals that GIV/girdin serves as a tunable valve for EGFR-stimulated cyclic AMP signals. Mol Biol Cell. 2019 06 15; 30(13):1621-1633. Getz M, Swanson L, Sahoo D, Ghosh P, Rangamani P. PMID: 31017840; PMCID: PMC6727633.
View in: PubMed Mentions: 9 Fields:
Translation:HumansCells - Near-Infrared Light-Activated DNA-Agonist Nanodevice for Nongenetically and Remotely Controlled Cellular Signaling and Behaviors in Live Animals. Nano Lett. 2019 04 10; 19(4):2603-2613. Wang M, He F, Li H, Yang S, Zhang J, Ghosh P, Wang HH, Nie Z. PMID: 30907088; PMCID: PMC6530480.
View in: PubMed Mentions: 13 Fields:
Translation:HumansCells - Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3. Pharmacol Rep. 2019 Apr; 71(2):289-298. Abd El-Hafeez AA, Khalifa HO, Mahdy EAM, Sharma V, Hosoi T, Ghosh P, Ozawa K, Montano MM, Fujimura T, Ibrahim ARN, Abdelhamid MAA, Pack SP, Shouman SA, Kawamoto S. PMID: 30826569; PMCID: PMC6536637.
View in: PubMed Mentions: 18 Fields:
Translation:HumansCells - Prognostic Relevance of CCDC88C (Daple) Transcripts in the Peripheral Blood of Patients with Cutaneous Melanoma. Sci Rep. 2018 12 21; 8(1):18036. Dunkel Y, Reid AL, Ear J, Aznar N, Millward M, Gray E, Pearce R, Ziman M, Ghosh P. PMID: 30575751; PMCID: PMC6303298.
View in: PubMed Mentions: 7 Fields:
Translation:HumansCells - Single-Cell Imaging of Metastatic Potential of Cancer Cells. iScience. 2018 Dec 21; 10:53-65. Midde K, Sun N, Rohena C, Joosen L, Dhillon H, Ghosh P. PMID: 30500482; PMCID: PMC6263091.
View in: PubMed Mentions: 9 - The waning of the WIMP? A review of models, searches, and constraints. Eur Phys J C Part Fields. 2018; 78(3):203. Arcadi G, Dutra M, Ghosh P, Lindner M, Mambrini Y, Pierre M, Profumo S, Queiroz FS. PMID: 31258403; PMCID: PMC6560773.
View in: PubMed Mentions: 4 - Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple. Sci Signal. 2018 02 27; 11(519). Aznar N, Ear J, Dunkel Y, Sun N, Satterfield K, He F, Kalogriopoulos NA, Lopez-Sanchez I, Ghassemian M, Sahoo D, Kufareva I, Ghosh P. PMID: 29487190; PMCID: PMC5862031.
View in: PubMed Mentions: 20 Fields:
Translation:HumansCells - A Daple-Akt feed-forward loop enhances noncanonical Wnt signals by compartmentalizing β-catenin. Mol Biol Cell. 2017 Dec 01; 28(25):3709-3723. Aznar N, Sun N, Dunkel Y, Ear J, Buschman MD, Ghosh P. PMID: 29021338; PMCID: PMC5706997.
View in: PubMed Mentions: 10 Fields:
Translation:HumansCells - The Alzheimer's disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool. J Biol Chem. 2017 09 15; 292(37):15312-15320. Siddiqui SS, Springer SA, Verhagen A, Sundaramurthy V, Alisson-Silva F, Jiang W, Ghosh P, Varki A. PMID: 28747436; PMCID: PMC5602391.
View in: PubMed Mentions: 38 Fields:
Translation:HumansCells - Erythrocyte sialoglycoproteins engage Siglec-9 on neutrophils to suppress activation. Blood. 2017 06 08; 129(23):3100-3110. Lizcano A, Secundino I, Döhrmann S, Corriden R, Rohena C, Diaz S, Ghosh P, Deng L, Nizet V, Varki A. PMID: 28416510; PMCID: PMC5465837.
View in: PubMed Mentions: 56 Fields:
Translation:HumansCells - The GAPs, GEFs, GDIs and…now, GEMs: New kids on the heterotrimeric G protein signaling block. Cell Cycle. 2017 Apr 03; 16(7):607-612. Ghosh P, Rangamani P, Kufareva I. PMID: 28287365; PMCID: PMC5397260.
View in: PubMed Mentions: 34 Fields:
Translation:HumansAnimalsCells - The stress polarity pathway: AMPK 'GIV'-es protection against metabolic insults. Aging (Albany NY). 2017 02 15; 9(2):303-314. Ghosh P. PMID: 28209925; PMCID: PMC5361665.
View in: PubMed Mentions: 9 Fields:
Translation:HumansAnimalsCells - Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin. Curr Protoc Chem Biol. 2016 Dec 07; 8(4):265-298. Ghosh P, Aznar N, Swanson L, Lo IC, Lopez-Sanchez I, Ear J, Rohena C, Kalogriopoulos N, Joosen L, Dunkel Y, Sun N, Nguyen P, Bhandari D. PMID: 27925669; PMCID: PMC5154557.
View in: PubMed Mentions: 4 Fields:
Translation:HumansAnimalsCells - AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin. Elife. 2016 11 04; 5. Aznar N, Patel A, Rohena CC, Dunkel Y, Joosen LP, Taupin V, Kufareva I, Farquhar MG, Ghosh P. PMID: 27813479; PMCID: PMC5119889.
View in: PubMed Mentions: 25 Fields:
Translation:HumansAnimalsCells - GIV/Girdin activates Gαi and inhibits Gαs via the same motif. Proc Natl Acad Sci U S A. 2016 09 27; 113(39):E5721-30. Gupta V, Bhandari D, Leyme A, Aznar N, Midde KK, Lo IC, Ear J, Niesman I, López-Sánchez I, Blanco-Canosa JB, von Zastrow M, Garcia-Marcos M, Farquhar MG, Ghosh P. PMID: 27621449; PMCID: PMC5047194.
View in: PubMed Mentions: 28 Fields:
Translation:HumansCells - Mitochondrial BMI1 maintains bioenergetic homeostasis in cells. FASEB J. 2016 12; 30(12):4042-4055. Banerjee Mustafi S, Aznar N, Dwivedi SK, Chakraborty PK, Basak R, Mukherjee P, Ghosh P, Bhattacharya R. PMID: 27613804; PMCID: PMC5102112.
View in: PubMed Mentions: 24 Fields:
Translation:HumansAnimalsCells - Prognostic impact of total and tyrosine phosphorylated GIV/Girdin in breast cancers. FASEB J. 2016 11; 30(11):3702-3713. Dunkel Y, Diao K, Aznar N, Swanson L, Liu L, Zhu W, Mi XY, Ghosh P. PMID: 27440794; PMCID: PMC5067257.
View in: PubMed Mentions: 7 Fields:
Translation:HumansCells - Glycan Sulfation Modulates Dendritic Cell Biology and Tumor Growth. Neoplasia. 2016 05; 18(5):294-306. El Ghazal R, Yin X, Johns SC, Swanson L, Macal M, Ghosh P, Zuniga EI, Fuster MM. PMID: 27237321; PMCID: PMC4887599.
View in: PubMed Mentions: 18 Fields:
Translation:HumansAnimalsCells - Girdin (GIV) Expression as a Prognostic Marker of Recurrence in Mismatch Repair-Proficient Stage II Colon Cancer. Clin Cancer Res. 2016 07 15; 22(14):3488-98. Ghosh P, Tie J, Muranyi A, Singh S, Brunhoeber P, Leith K, Bowermaster R, Liao Z, Zhu Y, LaFleur B, Tran B, Desai J, Jones I, Croxford M, Jover R, Goel A, Waring P, Hu S, Teichgraber V, Rohr UP, Ridder R, Shanmugam K, Gibbs P. PMID: 27029492; PMCID: PMC4947424.
View in: PubMed Mentions: 19 Fields:
Translation:HumansCells - Prognostic Impact of Modulators of G proteins in Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer. Sci Rep. 2016 Feb 26; 6:22112. Barbazan J, Dunkel Y, Li H, Nitsche U, Janssen KP, Messer K, Ghosh P. PMID: 26916336; PMCID: PMC4768264.
View in: PubMed Mentions: 29 Fields:
Translation:HumansCells - Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time. Bioessays. 2016 Apr; 38(4):379-93. Aznar N, Kalogriopoulos N, Midde KK, Ghosh P. PMID: 26879989; PMCID: PMC5123561.
View in: PubMed Mentions: 32 Fields:
Translation:HumansCells - The untapped potential of tyrosine-based G protein signaling. Pharmacol Res. 2016 Mar; 105:99-107. Ghosh P. PMID: 26808081; PMCID: PMC4775314.
View in: PubMed Mentions: 8 Fields:
Translation:HumansAnimalsCells - GIV/girdin binds exocyst subunit-Exo70 and regulates exocytosis of GLUT4 storage vesicles. Biochem Biophys Res Commun. 2015 Dec 4-11; 468(1-2):287-93. Lopez-Sanchez I, Ma GS, Pedram S, Kalogriopoulos N, Ghosh P. PMID: 26514725; PMCID: PMC4659757.
View in: PubMed Mentions: 7 Fields:
Translation:HumansAnimalsCells - Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins. Mol Biol Cell. 2015 Dec 01; 26(24):4313-24. Lopez-Sanchez I, Kalogriopoulos N, Lo IC, Kabir F, Midde KK, Wang H, Ghosh P. PMID: 26446841; PMCID: PMC4666128.
View in: PubMed Mentions: 16 Fields:
Translation:HumansAnimalsCells - Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity. Mol Biol Cell. 2015 Nov 15; 26(23):4209-23. Ma GS, Lopez-Sanchez I, Aznar N, Kalogriopoulos N, Pedram S, Midde K, Ciaraldi TP, Henry RR, Ghosh P. PMID: 26378251; PMCID: PMC4642855.
View in: PubMed Mentions: 12 Fields:
Translation:HumansCells - Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):E4874-83. Bhandari D, Lopez-Sanchez I, To A, Lo IC, Aznar N, Leyme A, Gupta V, Niesman I, Maddox AL, Garcia-Marcos M, Farquhar MG, Ghosh P. PMID: 26286990; PMCID: PMC4568279.
View in: PubMed Mentions: 41 Fields:
Translation:HumansAnimalsCells - Heterotrimeric G proteins as emerging targets for network based therapy in cancer: End of a long futile campaign striking heads of a Hydra. Aging (Albany NY). 2015 Jul; 7(7):469-74. Ghosh P. PMID: 26224586; PMCID: PMC4543036.
View in: PubMed Mentions: 30 Fields:
Translation:Humans - G protein coupled growth factor receptor tyrosine kinase: no longer an oxymoron. Cell Cycle. 2015; 14(16):2561-5. Ghosh P. PMID: 26126131; PMCID: PMC4613836.
View in: PubMed Mentions: 11 Fields:
Translation:HumansAnimalsCells - Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling. Elife. 2015 Jun 30; 4:e07091. Aznar N, Midde KK, Dunkel Y, Lopez-Sanchez I, Pavlova Y, Marivin A, Barbazán J, Murray F, Nitsche U, Janssen KP, Willert K, Goel A, Abal M, Garcia-Marcos M, Ghosh P. PMID: 26126266; PMCID: PMC4484057.
View in: PubMed Mentions: 76 Fields:
Translation:HumansCells - Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):E2602-10. Ma GS, Aznar N, Kalogriopoulos N, Midde KK, Lopez-Sanchez I, Sato E, Dunkel Y, Gallo RL, Ghosh P. PMID: 25926659; PMCID: PMC4443320.
View in: PubMed Mentions: 29 Fields:
Translation:HumansAnimalsCells - Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling. Dev Cell. 2015 Apr 20; 33(2):189-203. Lo IC, Gupta V, Midde KK, Taupin V, Lopez-Sanchez I, Kufareva I, Abagyan R, Randazzo PA, Farquhar MG, Ghosh P. PMID: 25865347; PMCID: PMC4415880.
View in: PubMed Mentions: 28 Fields:
Translation:HumansAnimalsCells - Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):E937-46. Midde KK, Aznar N, Laederich MB, Ma GS, Kunkel MT, Newton AC, Ghosh P. PMID: 25713130; PMCID: PMC4352799.
View in: PubMed Mentions: 37 Fields:
Translation:HumansAnimalsCells - GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation. J Biol Chem. 2015 Mar 13; 290(11):6697-704. Garcia-Marcos M, Ghosh P, Farquhar MG. PMID: 25605737; PMCID: PMC4358093.
View in: PubMed Mentions: 57 Fields:
Translation:HumansAnimalsCells - Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin. Mol Biol Cell. 2014 Nov 05; 25(22):3654-71. Lin C, Ear J, Midde K, Lopez-Sanchez I, Aznar N, Garcia-Marcos M, Kufareva I, Abagyan R, Ghosh P. PMID: 25187647; PMCID: PMC4230624.
View in: PubMed Mentions: 48 Fields:
Translation:HumansAnimalsCells - Correction: Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin. Genome Med. 2014; 6(7):53. Alakus H, Babicky ML, Ghosh P, Yost S, Jepsen K, Dai Y, Arias A, Samuels ML, Mose ES, Schwab RB, Peterson MR, Lowy AM, Frazer KA, Harismendy O. PMID: 25228923; PMCID: PMC4165363.
View in: PubMed Mentions: 2 Fields: - GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. Nat Commun. 2014 Jul 21; 5:4451. Lopez-Sanchez I, Dunkel Y, Roh YS, Mittal Y, De Minicis S, Muranyi A, Singh S, Shanmugam K, Aroonsakool N, Murray F, Ho SB, Seki E, Brenner DA, Ghosh P. PMID: 25043713; PMCID: PMC4107319.
View in: PubMed Mentions: 55 Fields:
Translation:HumansAnimalsCells - GIV/girdin links vascular endothelial growth factor signaling to Akt survival signaling in podocytes independent of nephrin. J Am Soc Nephrol. 2015 Feb; 26(2):314-27. Wang H, Misaki T, Taupin V, Eguchi A, Ghosh P, Farquhar MG. PMID: 25012178; PMCID: PMC4310647.
View in: PubMed Mentions: 32 Fields:
Translation:AnimalsCells - Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin. Genome Med. 2014; 6(5):43. Alakus H, Babicky ML, Ghosh P, Yost S, Jepsen K, Dai Y, Arias A, Samuels ML, Mose ES, Schwab RB, Peterson MR, Lowy AM, Frazer KA, Harismendy O. PMID: 24944587; PMCID: PMC4062050.
View in: PubMed Mentions: 55 Fields: - Direct inhibition of retinoblastoma phosphorylation by nimbolide causes cell-cycle arrest and suppresses glioblastoma growth. Clin Cancer Res. 2014 Jan 01; 20(1):199-212. Karkare S, Chhipa RR, Anderson J, Liu X, Henry H, Gasilina A, Nassar N, Ghosh J, Clark JP, Kumar A, Pauletti GM, Ghosh PK, Dasgupta B. PMID: 24170547; PMCID: PMC3947304.
View in: PubMed Mentions: 17 Fields:
Translation:HumansAnimalsCells - Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5510-5. López-Sánchez I, Garcia-Marcos M, Mittal Y, Aznar N, Farquhar MG, Ghosh P. PMID: 23509302; PMCID: PMC3619294.
View in: PubMed Mentions: 29 Fields:
Translation:HumansCells - STAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis. J Biol Chem. 2012 Dec 07; 287(50):41667-83. Dunkel Y, Ong A, Notani D, Mittal Y, Lam M, Mi X, Ghosh P. PMID: 23066027; PMCID: PMC3516717.
View in: PubMed Mentions: 36 Fields:
Translation:HumansCells - Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, et al. PMID: 22966490; PMCID: PMC3404883.
View in: PubMed Mentions: 1862 Fields:
Translation:HumansAnimals - Functional characterization of the guanine nucleotide exchange factor (GEF) motif of GIV protein reveals a threshold effect in signaling. Proc Natl Acad Sci U S A. 2012 Feb 07; 109(6):1961-6. Garcia-Marcos M, Kietrsunthorn PS, Pavlova Y, Adia MA, Ghosh P, Farquhar MG. PMID: 22308453; PMCID: PMC3277514.
View in: PubMed Mentions: 32 Fields:
Translation:HumansCells - Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration. Sci Signal. 2011 Sep 27; 4(192):ra64. Lin C, Ear J, Pavlova Y, Mittal Y, Kufareva I, Ghassemian M, Abagyan R, Garcia-Marcos M, Ghosh P. PMID: 21954290; PMCID: PMC4226136.
View in: PubMed Mentions: 53 Fields:
Translation:HumansCells - Phosphorylation of podocalyxin (Ser415) Prevents RhoA and ezrin activation and disrupts its interaction with the actin cytoskeleton. Am J Pathol. 2011 Nov; 179(5):2254-65. Fukasawa H, Obayashi H, Schmieder S, Lee J, Ghosh P, Farquhar MG. PMID: 21945805; PMCID: PMC3204015.
View in: PubMed Mentions: 13 Fields:
Translation:AnimalsCells - Src homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway. J Biol Chem. 2011 Sep 16; 286(37):32404-15. Mittal Y, Pavlova Y, Garcia-Marcos M, Ghosh P. PMID: 21799016; PMCID: PMC3173146.
View in: PubMed Mentions: 26 Fields:
Translation:HumansAnimalsCells - G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifs. J Biol Chem. 2011 Aug 12; 286(32):28138-49. Garcia-Marcos M, Kietrsunthorn PS, Wang H, Ghosh P, Farquhar MG. PMID: 21653697; PMCID: PMC3151059.
View in: PubMed Mentions: 37 Fields:
Translation:HumansAnimalsCells - Sequential interactions with Sec23 control the direction of vesicle traffic. Nature. 2011 May 12; 473(7346):181-6. Lord C, Bhandari D, Menon S, Ghassemian M, Nycz D, Hay J, Ghosh P, Ferro-Novick S. PMID: 21532587; PMCID: PMC3093450.
View in: PubMed Mentions: 111 Fields:
Translation:AnimalsCells - GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression. Cell Adh Migr. 2011 May-Jun; 5(3):237-48. Ghosh P, Garcia-Marcos M, Farquhar MG. PMID: 21546796; PMCID: PMC3210208.
View in: PubMed Mentions: 42 Fields:
Translation:HumansAnimalsCells - A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals. Mol Biol Cell. 2011 Mar 01; 22(5):673-86. Garcia-Marcos M, Ear J, Farquhar MG, Ghosh P. PMID: 21209316; PMCID: PMC3046063.
View in: PubMed Mentions: 71 Fields:
Translation:HumansCells - Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer. FASEB J. 2011 Feb; 25(2):590-9. Garcia-Marcos M, Jung BH, Ear J, Cabrera B, Carethers JM, Ghosh P. PMID: 20974669; PMCID: PMC3023389.
View in: PubMed Mentions: 52 Fields:
Translation:HumansCells - Achalasia, alcohol-stasis, and acute necrotizing esophagitis: connecting the dots. Dig Dis Sci. 2011 Feb; 56(2):612-4. Lee JK, Bhargava V, Mittal RK, Ghosh P. PMID: 20552400; PMCID: PMC3029818.
View in: PubMed Mentions: 4 Fields:
Translation:Humans - A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate. Mol Biol Cell. 2010 Jul 01; 21(13):2338-54. Ghosh P, Beas AO, Bornheimer SJ, Garcia-Marcos M, Forry EP, Johannson C, Ear J, Jung BH, Cabrera B, Carethers JM, Farquhar MG. PMID: 20462955; PMCID: PMC2893996.
View in: PubMed Mentions: 106 Fields:
Translation:HumansCells - A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration. J Biol Chem. 2010 Apr 23; 285(17):12765-77. Garcia-Marcos M, Ghosh P, Ear J, Farquhar MG. PMID: 20157114; PMCID: PMC2857069.
View in: PubMed Mentions: 66 Fields:
Translation:HumansAnimalsCells - Multiple "apple-core" lesions in chronic ischemic colitis: the great masquerader. Am J Gastroenterol. 2009 Nov; 104(11):2870-2. Ghosh P, Carethers JM. PMID: 19888260; PMCID: PMC6701951.
View in: PubMed Mentions: Fields:
Translation:Humans - ArterioVenous Malformation within Jejunal Diverticulum: an unusual cause of massive gastrointestinal bleeding. Gastroenterol Res Pract. 2009; 2009:384506. Lee JK, Carethers JM, Ghosh P. PMID: 19753317; PMCID: PMC2742646.
View in: PubMed Mentions: 4 - Generalized megaviscera of lupus: refractory intestinal pseudo-obstruction, ureterohydronephrosis and megacholedochus. World J Gastroenterol. 2009 Jul 28; 15(28):3555-9. Park FD, Lee JK, Madduri GD, Ghosh P. PMID: 19630114; PMCID: PMC2715985.
View in: PubMed Mentions: 13 Fields:
Translation:Humans - GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3178-83. Garcia-Marcos M, Ghosh P, Farquhar MG. PMID: 19211784; PMCID: PMC2651282.
View in: PubMed Mentions: 131 Fields:
Translation:HumansAnimalsCells - Activation of Galphai3 triggers cell migration via regulation of GIV. J Cell Biol. 2008 Jul 28; 182(2):381-93. Ghosh P, Garcia-Marcos M, Bornheimer SJ, Farquhar MG. PMID: 18663145; PMCID: PMC2483528.
View in: PubMed Mentions: 101 Fields:
Translation:HumansAnimalsCells - Evidence for colorectal sarcomatoid carcinoma arising from tubulovillous adenoma. World J Gastroenterol. 2008 Jul 21; 14(27):4389-94. Lee JK, Ghosh P, McWhorter V, Payne M, Olson R, Krinsky ML, Ramamoorthy S, Carethers JM. PMID: 18666331; PMCID: PMC2731194.
View in: PubMed Mentions: 10 Fields:
Translation:Humans - Nonmetastatic cancer of the colon associated with pyogenic liver abscess. Am J Gastroenterol. 2008 Mar; 103(3):798-9. Lee JK, Kum J, Ghosh P. PMID: 18341498.
View in: PubMed Mentions: 6 Fields:
Translation:Humans - Sugar rush in the colon: why incidental findings on PET scan justify colonoscopy? Am J Gastroenterol. 2007 Nov; 102(11):2609-10. Ghosh P, Olson RK, Harmon G. PMID: 17958772.
View in: PubMed Mentions: Fields:
Translation:Humans - Gastric adenocarcinoma inducing portal hypertension: a rare presentation. World J Gastroenterol. 2007 Feb 14; 13(6):960-3. Ghosh P, Miyai K, Chojkier M. PMID: 17352032; PMCID: PMC4065938.
View in: PubMed Mentions: 1 Fields:
Translation:Humans - Mesenteric panniculitis and sclerosing mesenteritis: a continuum of inflammation fibrosis. Clin Gastroenterol Hepatol. 2007 May; 5(5):A32. Ghosh P, Kum J. PMID: 17261382.
View in: PubMed Mentions: Fields:
Translation:Humans - Peritoneal mice implicated in intestinal obstruction: report of a case and review of the literature. J Clin Gastroenterol. 2006 May-Jun; 40(5):427-30. Ghosh P, Strong C, Naugler W, Haghighi P, Carethers JM. PMID: 16721225.
View in: PubMed Mentions: 20 Fields:
Translation:Humans - The GGA proteins: key players in protein sorting at the trans-Golgi network. Eur J Cell Biol. 2004 Jul; 83(6):257-62. Ghosh P, Kornfeld S. PMID: 15511083.
View in: PubMed Mentions: 41 Fields:
Translation:HumansAnimalsCells - The cytoplasmic tail of the cation-independent mannose 6-phosphate receptor contains four binding sites for AP-1. Arch Biochem Biophys. 2004 Jun 15; 426(2):225-30. Ghosh P, Kornfeld S. PMID: 15158672.
View in: PubMed Mentions: 26 Fields:
Translation:Cells - Mammalian GGAs act together to sort mannose 6-phosphate receptors. J Cell Biol. 2003 Nov 24; 163(4):755-66. Ghosh P, Griffith J, Geuze HJ, Kornfeld S. PMID: 14638859; PMCID: PMC2173681.
View in: PubMed Mentions: 50 Fields:
Translation:HumansCells - Mannose 6-phosphate receptors: new twists in the tale. Nat Rev Mol Cell Biol. 2003 Mar; 4(3):202-12. Ghosh P, Dahms NM, Kornfeld S. PMID: 12612639.
View in: PubMed Mentions: 468 Fields:
Translation:HumansAnimalsCells - AP-1 binding to sorting signals and release from clathrin-coated vesicles is regulated by phosphorylation. J Cell Biol. 2003 Mar 03; 160(5):699-708. Ghosh P, Kornfeld S. PMID: 12604586; PMCID: PMC2173368.
View in: PubMed Mentions: 44 Fields:
Translation:AnimalsCells - Phosphorylation-induced conformational changes regulate GGAs 1 and 3 function at the trans-Golgi network. J Biol Chem. 2003 Apr 18; 278(16):14543-9. Ghosh P, Kornfeld S. PMID: 12578827.
View in: PubMed Mentions: 20 Fields:
Translation:AnimalsCells - Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network. Science. 2002 Sep 06; 297(5587):1700-3. Doray B, Ghosh P, Griffith J, Geuze HJ, Kornfeld S. PMID: 12215646.
View in: PubMed Mentions: 122 Fields:
Translation:HumansAnimalsCells - Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8072-7. Doray B, Bruns K, Ghosh P, Kornfeld SA. PMID: 12060753; PMCID: PMC123022.
View in: PubMed Mentions: 26 Fields:
Translation:AnimalsCells - Human mannose 6-phosphate-uncovering enzyme is synthesized as a proenzyme that is activated by the endoprotease furin. J Biol Chem. 2002 Aug 16; 277(33):29737-44. Do H, Lee WS, Ghosh P, Hollowell T, Canfield W, Kornfeld S. PMID: 12058031.
View in: PubMed Mentions: 23 Fields:
Translation:HumansAnimalsCells - Interaction of the cation-dependent mannose 6-phosphate receptor with GGA proteins. J Biol Chem. 2002 May 24; 277(21):18477-82. Doray B, Bruns K, Ghosh P, Kornfeld S. PMID: 11886874.
View in: PubMed Mentions: 29 Fields:
Translation:Cells
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