Tapan Biswas • UCSD Profiles (original) (raw)

  1. Teamwork of clustered low-affinity κB sites and accessory factors regulates transcriptional strength of NF-κB RelA dimers. Nucleic Acids Res. 2025 Sep 23; 53(18). Shahabi S, Biswas T, Shen Y, Sanahmadi R, Zou Y, Ghosh G. PMID: 41063342; PMCID: PMC12507517.
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    Translation:HumansAnimalsCells
  2. F2,6BP restores mitochondrial genome integrity in Huntington's Disease. bioRxiv. 2025 Jun 30. Chakraborty A, Mandal SM, Mankevich M, Mani RS, Shahabi S, Biswas T, Kodavati M, Sreenivasmurthy SG, Tapryal N, Krishnan B, Hegde ML, Weinfeld M, Ghosh G, Hazra T. PMID: 39574700; PMCID: PMC11580889.
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  3. Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate. Elife. 2025 Jun 30; 13. Borar P, Biswas T, Chaudhuri A, Rao PT, Raychaudhuri S, Huxford T, Chakrabarti S, Ghosh G, Polley S. PMID: 40586777; PMCID: PMC12208667.
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    Translation:HumansCells
  4. Cooperativity among clustered κB sites within promoters and enhancers dictates transcriptional specificity of NF-κB RelA along with specific cofactors. bioRxiv. 2025 Jun 18. Shahabi S, Biswas T, Shen Y, Sanahmadi R, Zou Y, Ghosh G. PMID: 39411157; PMCID: PMC11475870.
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  5. RNA control of reverse transcription in a diversity-generating retroelement. Nature. 2025 Feb; 638(8052):1122-1129. Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG, Ghosh P. PMID: 39779855; PMCID: PMC11995886.
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    Translation:Cells
  6. Phosphorylation-induced flexibility of proto-oncogenic Bcl3 regulates transcriptional activation by NF-κB p52 homodimer. bioRxiv. 2024 Oct 23. Pan W, Biswas T, Shahabi S, Suryajaya W, Vasquez A, Du Q, Ghosh G, Wang VY. PMID: 38979190; PMCID: PMC11230411.
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  7. Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's disease. Proc Natl Acad Sci U S A. 2024 Sep 24; 121(39):e2406308121. Chakraborty A, Sreenivasmurthy SG, Miller W, Huai W, Biswas T, Mandal SM, Boscá L, Krishnan B, Ghosh G, Hazra T. PMID: 39298485; PMCID: PMC11441552.
    View in: PubMed Mentions: 2 Fields:
    Translation:HumansAnimalsCells
  8. HDX-MS Analysis of Catalytic Activation of IKK2 in the IκB Kinase Complex. Biochemistry. 2024 09 17; 63(18):2323-2334. Suryajaya W, Biswas T, Shahabi S, Mealka M, Huxford T, Ghosh G. PMID: 39185716; PMCID: PMC11731525.
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    Translation:HumansCells
  9. Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's disease. bioRxiv. 2024 Jul 16. Chakraborty A, Sreenivasmurthy SG, Miller W, Huai W, Biswas T, Mandal SM, Boscá L, Krishnan B, Ghosh G, Hazra T. PMID: 37961108; PMCID: PMC10634858.
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  10. Structural Requirements for Reverse Transcription by a Diversity-generating Retroelement. bioRxiv. 2024 Jun 12. Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG, Ghosh P. PMID: 37961358; PMCID: PMC10634737.
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  11. Transient interactions modulate the affinity of NF-κB transcription factors for DNA. Proc Natl Acad Sci U S A. 2024 Jun 04; 121(23):e2405555121. Li T, Shahabi S, Biswas T, Tsodikov OV, Pan W, Huang DB, Wang VY, Wang Y, Ghosh G. PMID: 38805268; PMCID: PMC11161749.
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    Translation:HumansCells
  12. Regulatory subunit NEMO promotes polyubiquitin-dependent induction of NF-κB through a targetable second interaction with upstream activator IKK2. J Biol Chem. 2022 05; 298(5):101864. Ko MS, Cohen SN, Polley S, Mahata SK, Biswas T, Huxford T, Ghosh G. PMID: 35339487; PMCID: PMC9035715.
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    Translation:HumansCells
  13. Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code. Nucleic Acids Res. 2021 07 09; 49(12):7103-7121. Saha K, Fernandez MM, Biswas T, Joseph S, Ghosh G. PMID: 34161584; PMCID: PMC8266590.
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    Translation:HumansCells
  14. Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution. Biochim Biophys Acta Proteins Proteom. 2020 12; 1868(12):140526. Ko MS, Biswas T, Mulero MC, Bobkov AA, Ghosh G, Huxford T. PMID: 32853772; PMCID: PMC7994000.
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    Translation:HumansCells
  15. CD1d Selectively Down Regulates the Expression of the Oxidized Phospholipid-Specific E06 IgM Natural Antibody in Ldlr-/- Mice. Antibodies (Basel). 2020 Jul 03; 9(3). Biswas TK, VanderLaan PA, Que X, Gonen A, Krishack P, Binder CJ, Witztum JL, Getz GS, Reardon CA. PMID: 32635160; PMCID: PMC7551411.
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  16. Structural disruption of exonic stem-loops immediately upstream of the intron regulates mammalian splicing. Nucleic Acids Res. 2020 06 19; 48(11):6294-6309. Saha K, England W, Fernandez MM, Biswas T, Spitale RC, Ghosh G. PMID: 32402057; PMCID: PMC7293017.
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    Translation:AnimalsCells
  17. A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α. J Vis Exp. 2018 11 02; (141). Polley S, Huang DB, Biswas T, Ghosh G. PMID: 30451218.
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    Translation:HumansAnimalsCells
  18. Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events. Biochemistry. 2018 04 10; 57(14):2084-2093. Hou C, Biswas T, Tsodikov OV. PMID: 29558114.
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    Translation:Cells
  19. Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight. Biochemistry. 2018 02 06; 57(5):781-790. Green KD, Biswas T, Pang AH, Willby MJ, Reed MS, Stuchlik O, Pohl J, Posey JE, Tsodikov OV, Garneau-Tsodikova S. PMID: 29345920; PMCID: PMC5971062.
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    Translation:Cells
  20. DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor κB are not correlated. J Biol Chem. 2017 11 17; 292(46):18821-18830. Mulero MC, Huang DB, Nguyen HT, Wang VY, Li Y, Biswas T, Ghosh G. PMID: 28935669; PMCID: PMC5704467.
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    Translation:AnimalsCells
  21. Erratum: Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol. 2017 Jun 12; 2:17107. Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P. PMID: 28604710.
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  22. Structural Basis for the Activation of IKK1/α. Cell Rep. 2016 11 15; 17(8):1907-1914. Polley S, Passos DO, Huang DB, Mulero MC, Mazumder A, Biswas T, Verma IM, Lyumkis D, Ghosh G. PMID: 27851956; PMCID: PMC5508515.
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    Translation:HumansCells
  23. To Swap or Not To Swap. Structure. 2016 09 06; 24(9):1436-8. Ghosh G, Biswas T. PMID: 27602989.
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    Translation:Cells
  24. Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol. 2016 Sep 05; 1(11):16155. Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P. PMID: 27595425; PMCID: PMC5014329.
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    Translation:HumansCells
  25. Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis. J Struct Biol. 2015 Oct; 192(1):76-87. Pratt AC, Dewage SW, Pang AH, Biswas T, Barnard-Britson S, Cisneros GA, Tsodikov OV. PMID: 26296329.
    View in: PubMed Mentions: 5 Fields:
    Translation:Cells
  26. Biochemical and structural analysis of an Eis family aminoglycoside acetyltransferase from bacillus anthracis. Biochemistry. 2015 May 26; 54(20):3197-206. Green KD, Biswas T, Chang C, Wu R, Chen W, Janes BK, Chalupska D, Gornicki P, Hanna PC, Tsodikov OV, Joachimiak A, Garneau-Tsodikova S. PMID: 25928210; PMCID: PMC4671295.
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    Translation:Cells
  27. Discovery of inhibitors of Bacillus anthracis primase DnaG. Biochemistry. 2013 Oct 01; 52(39):6905-10. Biswas T, Green KD, Garneau-Tsodikova S, Tsodikov OV. PMID: 24004110.
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    Translation:AnimalsCells
  28. DksA2, a zinc-independent structural analog of the transcription factor DksA. FEBS Lett. 2013 Mar 18; 587(6):614-9. Furman R, Biswas T, Danhart EM, Foster MP, Tsodikov OV, Artsimovitch I. PMID: 23416301; PMCID: PMC5525025.
    View in: PubMed Mentions: 26 Fields:
    Translation:Cells
  29. A novel non-radioactive primase-pyrophosphatase activity assay and its application to the discovery of inhibitors of Mycobacterium tuberculosis primase DnaG. Nucleic Acids Res. 2013 Feb 01; 41(4):e56. Biswas T, Resto-Roldán E, Sawyer SK, Artsimovitch I, Tsodikov OV. PMID: 23267008; PMCID: PMC3575809.
    View in: PubMed Mentions: 20 Fields:
    Translation:Cells
  30. Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9804-8. Chen W, Biswas T, Porter VR, Tsodikov OV, Garneau-Tsodikova S. PMID: 21628583; PMCID: PMC3116390.
    View in: PubMed Mentions: 84 Fields:
    Translation:HumansCells
  31. Structural and thermodynamic signatures of DNA recognition by Mycobacterium tuberculosis DnaA. J Mol Biol. 2011 Jul 15; 410(3):461-76. Tsodikov OV, Biswas T. PMID: 21620858.
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    Translation:Cells
  32. Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress. Structure. 2010 Oct 13; 18(10):1353-63. Biswas T, Small J, Vandal O, Odaira T, Deng H, Ehrt S, Tsodikov OV. PMID: 20947023; PMCID: PMC2955984.
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    Translation:Cells
  33. A new scaffold of an old protein fold ensures binding to the bisintercalator thiocoraline. J Mol Biol. 2010 Mar 26; 397(2):495-507. Biswas T, Zolova OE, Lombó F, de la Calle F, Salas JA, Tsodikov OV, Garneau-Tsodikova S. PMID: 20122935.
    View in: PubMed Mentions: 8 Fields:
    Translation:Cells
  34. DNA-dependent ATPase activity of bacterial XPB helicases. Biochemistry. 2009 Mar 31; 48(12):2839-48. Biswas T, Pero JM, Joseph CG, Tsodikov OV. PMID: 19199647.
    View in: PubMed Mentions: 15 Fields:
    Translation:Cells
  35. Architecture of the 99 bp DNA-six-protein regulatory complex of the lambda att site. Mol Cell. 2006 Nov 17; 24(4):569-80. Sun X, Mierke DF, Biswas T, Lee SY, Landy A, Radman-Livaja M. PMID: 17114059; PMCID: PMC1866956.
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    Translation:Cells
  36. A structural basis for allosteric control of DNA recombination by lambda integrase. Nature. 2005 Jun 23; 435(7045):1059-66. Biswas T, Aihara H, Radman-Livaja M, Filman D, Landy A, Ellenberger T. PMID: 15973401; PMCID: PMC1809751.
    View in: PubMed Mentions: 93 Fields:
    Translation:Cells

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This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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