Timothy Sears • UCSD Profiles (original) (raw)

  1. Genetic association and machine learning improve the prediction of type 1 diabetes risk. Nat Genet. 2026 Apr 30. McGrail C, Sears TJ, Griffin EN, Ghaben AL, Smadbeck P, Flannick J, Kudtarkar P, Carter H, Gaulton K. PMID: 42062540.
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  2. NeoPrecis: enhancing immunotherapy response prediction through integration of qualified immunogenicity and clonality-aware neoantigen landscapes. Nat Commun. 2026 01 23; 17(1). Lee KH, Sears TJ, Zanetti M, Carter H. PMID: 41577704; PMCID: PMC12932759.
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  3. Autoimmune HLA alleles and neoantigens predict myelodysplastic syndrome outcomes after allogeneic HSCT: A CIBMTR analysis. iScience. 2026 Jan 16; 29(1):114326. Sears T, Kurzrock R, Zhang T, Dong J, Spellman SR, Goodman AM, Bolon YT, Chen Z, Auer P, Saber W, Carter H. PMID: 41550735; PMCID: PMC12804621.
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  4. Distinct Sarcoma Microenvironments Predict Benefit from Addition of Pembrolizumab to Preoperative Radiotherapy and Surgery in SU2C-SARC032. medRxiv. 2025 Nov 04. Testa S, Himes JE, Subramanian A, Nouth SCL, Ballman KV, Heise RS, Pierpoint M, Nemat-Gorgani N, Sears TJ, Binkley MS, Kalbasi A, Corcoran DL, Hong AM, Brigman BE, Riedel RF, van de Rijn M, Mowery YM, Weinhold KJ, Kirsch DG, Moding EJ. PMID: 41282894; PMCID: PMC12637778.
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  5. NeoPrecis: Enhancing Immunotherapy Response Prediction through Integration of Qualified Immunogenicity and Clonality-Aware Neoantigen Landscapes. bioRxiv. 2025 Jul 27. Lee KH, Sears TJ, Zanetti M, Carter H. PMID: 40777306; PMCID: PMC12330539.
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  6. MHC Hammer Decodes HLA Disruption in Tumors. Cancer Res. 2025 Feb 17; 85(4):642-643. Sears T, Carter H. PMID: 39636736.
    View in: PubMed Mentions: 2 Fields:
    Translation:HumansCells
  7. Integrated Germline and Somatic Features Reveal Divergent Immune Pathways Driving Response to Immune Checkpoint Blockade. Cancer Immunol Res. 2024 Dec 03; 12(12):1780-1795. Sears TJ, Pagadala MS, Castro A, Lee KH, Kong J, Tanaka K, Lippman SM, Zanetti M, Carter H. PMID: 39255339; PMCID: PMC11612627.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansCells
  8. Genetic association and machine learning improves discovery and prediction of type 1 diabetes. medRxiv. 2024 Aug 02. McGrail C, Sears TJ, Kudtarkar P, Carter H, Gaulton K. PMID: 39132494; PMCID: PMC11312647.
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  9. Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy. Nat Cancer. 2024 04; 5(4):642-658. Subramanian A, Nemat-Gorgani N, Ellis-Caleo TJ, van IJzendoorn DGP, Sears TJ, Somani A, Luca BA, Zhou MY, Bradic M, Torres IA, Oladipo E, New C, Kenney DE, Avedian RS, Steffner RJ, Binkley MS, Mohler DG, Tap WD, D'Angelo SP, van de Rijn M, Ganjoo KN, Bui NQ, Charville GW, Newman AM, Moding EJ. PMID: 38429415; PMCID: PMC11058033.
    View in: PubMed Mentions: 19 Fields:
    Translation:HumansCells
  10. Integrated germline and somatic features reveal divergent immune pathways driving ICB response. bioRxiv. 2024 Jan 15. Sears T, Pagadala M, Castro A, Lee KH, Kong J, Tanaka K, Lippman S, Zanetti M, Carter H. PMID: 38293085; PMCID: PMC10827124.
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  11. Application of a Machine Learning Algorithm in Prediction of Abusive Head Trauma in Children. J Pediatr Surg. 2024 Jan; 59(1):80-85. Jadhav P, Sears T, Floan G, Joskowitz K, Nienow S, Cruz S, David M, de Cos V, Choi P, Ignacio RC. PMID: 37858394.
    View in: PubMed Mentions: 2 Fields:
    Translation:Humans
  12. Characterizing the role of Phlda3 in the development of acute toxicity and malignant transformation of hematopoietic cells induced by total-body irradiation in mice. Sci Rep. 2023 08 09; 13(1):12916. Hasapis S, Caraballo I, Sears TJ, Brock KD, Cart JB, Moding EJ, Lee CL. PMID: 37558703; PMCID: PMC10412554.
    View in: PubMed Mentions: 4 Fields:
    Translation:HumansAnimalsCells
  13. Monitoring Sarcoma Response to Immune Checkpoint Inhibition and Local Cryotherapy with Circulating Tumor DNA Analysis. Clin Cancer Res. 2023 07 14; 29(14):2612-2620. Bui NQ, Nemat-Gorgani N, Subramanian A, Torres IA, Lohman M, Sears TJ, van de Rijn M, Charville GW, Becker HC, Wang DS, Hwang GL, Ganjoo KN, Moding EJ. PMID: 37130154.
    View in: PubMed Mentions: 10 Fields:
    Translation:HumansCTClinical Trials
  14. Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response. Nat Commun. 2023 05 12; 14(1):2744. Pagadala M, Sears TJ, Wu VH, Pérez-Guijarro E, Kim H, Castro A, Talwar JV, Gonzalez-Colin C, Cao S, Schmiedel BJ, Goudarzi S, Kirani D, Au J, Zhang T, Landi T, Salem RM, Morris GP, Harismendy O, Patel SP, Alexandrov LB, Mesirov JP, Zanetti M, Day CP, Fan CC, Thompson WK, Merlino G, Gutkind JS, Vijayanand P, Carter H. PMID: 37173324; PMCID: PMC10182072.
    View in: PubMed Mentions: 26 Fields:
    Translation:Cells
  15. Differential regulation of TNFα and IL-6 expression contributes to immune evasion in prostate cancer. J Transl Med. 2022 11 12; 20(1):527. Deichaite I, Sears TJ, Sutton L, Rebibo D, Morgan K, Nelson T, Rose B, Tamayo P, Ferrara N, Asimakopoulos F, Carter H. PMID: 36371231; PMCID: PMC9652804.
    View in: PubMed Mentions: 19 Fields:
    Translation:Humans
  16. Germline genetic biomarkers to stratify patients for personalized radiation treatment. J Transl Med. 2022 08 12; 20(1):360. Deichaite I, Hopper A, Krockenberger L, Sears TJ, Sutton L, Ray X, Sharabi A, Navon A, Sanghvi P, Carter H, Moiseenko V. PMID: 35962345; PMCID: PMC9373374.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansCells

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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