William Joiner • UCSD Profiles (original) (raw)

  1. Protocol for multiplexed RNAscope-based imaging of mRNAs in whole-mount adult Drosophila brains. STAR Protoc. 2025 Mar 21; 6(1):103615. Wu M, Lambatan V, Guo P, Joiner WJ. PMID: 39891913; PMCID: PMC11835639.
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    Translation:Animals
  2. Timeless noncoding DNA contains cell-type preferential enhancers important for proper Drosophila circadian regulation. Proc Natl Acad Sci U S A. 2024 Apr 09; 121(15):e2321338121. Ma D, Ojha P, Yu AD, Araujo MS, Luo W, Keefer E, Díaz MM, Wu M, Joiner WJ, Abruzzi KC, Rosbash M. PMID: 38568969; PMCID: PMC11009632.
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  3. Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity. Acta Neuropathol Commun. 2023 10 17; 11(1):164. Bennett CL, Dastidar S, Arnold FJ, McKinstry SU, Stockford C, Freibaum BD, Sopher BL, Wu M, Seidner G, Joiner W, Taylor JP, West RJH, La Spada AR. PMID: 37845749; PMCID: PMC10580588.
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    Translation:HumansAnimalsCells
  4. Re-examining the role of the dorsal fan-shaped body in promoting sleep in Drosophila. Curr Biol. 2023 09 11; 33(17):3660-3668.e4. De J, Wu M, Lambatan V, Hua Y, Joiner WJ. PMID: 37552985; PMCID: PMC10573663.
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    Translation:Animals
  5. Inputs to the Sleep Homeostat Originate Outside the Brain. J Neurosci. 2022 Jul 20; 42(29):5695-5704. Satterfield LK, De J, Wu M, Qiu T, Joiner WJ. PMID: 35680412; PMCID: PMC9302467.
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  6. Unbalanced Regulation of α7 nAChRs by Ly6h and NACHO Contributes to Neurotoxicity in Alzheimer's Disease. J Neurosci. 2021 10 13; 41(41):8461-8474. Wu M, Liu CZ, Barrall EA, Rissman RA, Joiner WJ. PMID: 34446574; PMCID: PMC8513707.
    View in: PubMed Mentions: 17 Fields:
    Translation:HumansAnimalsCells
  7. Neuroscience: Sleep Fragmentation Impairs Memory Formation. Curr Biol. 2019 11 18; 29(22):R1181-R1184. Joiner WJ. PMID: 31743673.
    View in: PubMed Mentions: 7 Fields:
    Translation:Animals
  8. Amplification of Drosophila Olfactory Responses by a DEG/ENaC Channel. Neuron. 2019 12 04; 104(5):947-959.e5. Ng R, Salem SS, Wu ST, Wu M, Lin HH, Shepherd AK, Joiner WJ, Wang JW, Su CY. PMID: 31629603; PMCID: PMC6895426.
    View in: PubMed Mentions: 34 Fields:
    Translation:AnimalsCells
  9. The Neurobiological Basis of Sleep and Sleep Disorders. Physiology (Bethesda). 2018 09 01; 33(5):317-327. Joiner WJ. PMID: 30109824; PMCID: PMC6230548.
    View in: PubMed Mentions: 14 Fields:
    Translation:HumansAnimals
  10. Unraveling the Evolutionary Determinants of Sleep. Curr Biol. 2016 10 24; 26(20):R1073-R1087. Joiner WJ. PMID: 27780049; PMCID: PMC5120870.
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    Translation:Animals
  11. Using Drosophila as an integrated model to study mild repetitive traumatic brain injury. Sci Rep. 2016 05 04; 6:25252. Barekat A, Gonzalez A, Mauntz RE, Kotzebue RW, Molina B, El-Mecharrafie N, Conner CJ, Garza S, Melkani GC, Joiner WJ, Lipinski MM, Finley KD, Ratliff EP. PMID: 27143646; PMCID: PMC4855207.
    View in: PubMed Mentions: 49 Fields:
    Translation:Animals
  12. The mood stabilizer valproic acid opposes the effects of dopamine on circadian rhythms. Neuropharmacology. 2016 08; 107:262-270. Landgraf D, Joiner WJ, McCarthy MJ, Kiessling S, Barandas R, Young JW, Cermakian N, Welsh DK. PMID: 27033596.
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    Translation:HumansAnimalsCells
  13. Structural Analysis and Deletion Mutagenesis Define Regions of QUIVER/SLEEPLESS that Are Responsible for Interactions with Shaker-Type Potassium Channels and Nicotinic Acetylcholine Receptors. PLoS One. 2016; 11(2):e0148215. Wu M, Liu CZ, Joiner WJ. PMID: 26828958; PMCID: PMC4735452.
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    Translation:AnimalsCells
  14. ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity. Nat Commun. 2016 Jan 27; 7:10512. Robinson JE, Paluch J, Dickman DK, Joiner WJ. PMID: 26813350; PMCID: PMC4737855.
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    Translation:AnimalsCells
  15. Identification of Neurons with a Privileged Role in Sleep Homeostasis in Drosophila melanogaster. Curr Biol. 2015 Nov 16; 25(22):2928-38. Seidner G, Robinson JE, Wu M, Worden K, Masek P, Roberts SW, Keene AC, Joiner WJ. PMID: 26526372; PMCID: PMC4654679.
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    Translation:AnimalsCells
  16. Mechanisms of inhibition and potentiation of α4β2 nicotinic acetylcholine receptors by members of the Ly6 protein family. J Biol Chem. 2015 Oct 02; 290(40):24509-18. Wu M, Puddifoot CA, Taylor P, Joiner WJ. PMID: 26276394; PMCID: PMC4591831.
    View in: PubMed Mentions: 29 Fields:
    Translation:HumansAnimalsCells
  17. Aging and Autophagic Function Influences the Progressive Decline of Adult Drosophila Behaviors. PLoS One. 2015; 10(7):e0132768. Ratliff EP, Mauntz RE, Kotzebue RW, Gonzalez A, Achal M, Barekat A, Finley KA, Sparhawk JM, Robinson JE, Herr DR, Harris GL, Joiner WJ, Finley KD. PMID: 26182057; PMCID: PMC4504520.
    View in: PubMed Mentions: 26 Fields:
    Translation:AnimalsCells
  18. Nmf9 Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies. PLoS Genet. 2015 Jul; 11(7):e1005344. Zhang S, Ross KD, Seidner GA, Gorman MR, Poon TH, Wang X, Keithley EM, Lee PN, Martindale MQ, Joiner WJ, Hamilton BA. PMID: 26131556; PMCID: PMC4488434.
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    Translation:AnimalsCells
  19. Neurodegeneration: paying it off with sleep. Curr Biol. 2015 Mar 16; 25(6):R234-R236. Keene AC, Joiner WJ. PMID: 25784043; PMCID: PMC4381801.
    View in: PubMed Mentions: 4 Fields:
    Translation:HumansAnimals
  20. Ly6h regulates trafficking of alpha7 nicotinic acetylcholine receptors and nicotine-induced potentiation of glutamatergic signaling. J Neurosci. 2015 Feb 25; 35(8):3420-30. Puddifoot CA, Wu M, Sung RJ, Joiner WJ. PMID: 25716842; PMCID: PMC4339353.
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    Translation:HumansAnimalsCells
  21. SLEEPLESS is a bifunctional regulator of excitability and cholinergic synaptic transmission. Curr Biol. 2014 Mar 17; 24(6):621-9. Wu M, Robinson JE, Joiner WJ. PMID: 24613312; PMCID: PMC4059605.
    View in: PubMed Mentions: 46 Fields:
    Translation:AnimalsCells
  22. Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Mol Metab. 2014 Feb; 3(1):42-54. Heinrichsen ET, Zhang H, Robinson JE, Ngo J, Diop S, Bodmer R, Joiner WJ, Metallo CM, Haddad GG. PMID: 24567903; PMCID: PMC3929909.
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  23. Genetic and anatomical basis of the barrier separating wakefulness and anesthetic-induced unresponsiveness. PLoS Genet. 2013; 9(9):e1003605. Joiner WJ, Friedman EB, Hung HT, Koh K, Sowcik M, Sehgal A, Kelz MB. PMID: 24039590; PMCID: PMC3764144.
    View in: PubMed Mentions: 44 Fields:
    Translation:HumansAnimalsCells
  24. Drosophila QVR/SSS modulates the activation and C-type inactivation kinetics of Shaker K(+) channels. J Neurosci. 2011 Aug 03; 31(31):11387-95. Dean T, Xu R, Joiner W, Sehgal A, Hoshi T. PMID: 21813698; PMCID: PMC3183472.
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    Translation:HumansAnimalsCells
  25. A conserved behavioral state barrier impedes transitions between anesthetic-induced unconsciousness and wakefulness: evidence for neural inertia. PLoS One. 2010 Jul 30; 5(7):e11903. Friedman EB, Sun Y, Moore JT, Hung HT, Meng QC, Perera P, Joiner WJ, Thomas SA, Eckenhoff RG, Sehgal A, Kelz MB. PMID: 20689589; PMCID: PMC2912772.
    View in: PubMed Mentions: 108 Fields:
    Translation:Animals
  26. SLEEPLESS, a Ly-6/neurotoxin family member, regulates the levels, localization and activity of Shaker. Nat Neurosci. 2010 Jan; 13(1):69-75. Wu MN, Joiner WJ, Dean T, Yue Z, Smith CJ, Chen D, Hoshi T, Sehgal A, Koh K. PMID: 20010822; PMCID: PMC2842941.
    View in: PubMed Mentions: 67 Fields:
    Translation:HumansAnimalsCells
  27. Identification of SLEEPLESS, a sleep-promoting factor. Science. 2008 Jul 18; 321(5887):372-6. Koh K, Joiner WJ, Wu MN, Yue Z, Smith CJ, Sehgal A. PMID: 18635795; PMCID: PMC2771549.
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  28. A genetic screen for sleep and circadian mutants reveals mechanisms underlying regulation of sleep in Drosophila. Sleep. 2008 Apr; 31(4):465-72. Wu MN, Koh K, Yue Z, Joiner WJ, Sehgal A. PMID: 18457233; PMCID: PMC2279757.
    View in: PubMed Mentions: 71 Fields:
    Translation:AnimalsPHPublic Health
  29. Molecular analysis of sleep: wake cycles in Drosophila. Cold Spring Harb Symp Quant Biol. 2007; 72:557-64. Sehgal A, Joiner W, Crocker A, Koh K, Sathyanarayanan S, Fang Y, Wu M, Williams JA, Zheng X. PMID: 18419315.
    View in: PubMed Mentions: 15 Fields:
    Translation:Animals
  30. Sleep in Drosophila is regulated by adult mushroom bodies. Nature. 2006 Jun 08; 441(7094):757-60. Joiner WJ, Crocker A, White BH, Sehgal A. PMID: 16760980.
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    Translation:Animals
  31. A sleep-promoting role for the Drosophila serotonin receptor 1A. Curr Biol. 2006 Jun 06; 16(11):1051-62. Yuan Q, Joiner WJ, Sehgal A. PMID: 16753559.
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    Translation:Animals
  32. The appearance of a protein kinase A-regulated splice isoform of slo is associated with the maturation of neurons that control reproductive behavior. J Biol Chem. 2004 Dec 10; 279(50):52324-30. Zhang Y, Joiner WJ, Bhattacharjee A, Rassendren F, Magoski NS, Kaczmarek LK. PMID: 15375169.
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    Translation:AnimalsCells
  33. Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP. J Neurosci. 2003 Dec 17; 23(37):11681-91. Bhattacharjee A, Joiner WJ, Wu M, Yang Y, Sigworth FJ, Kaczmarek LK. PMID: 14684870; PMCID: PMC6740956.
    View in: PubMed Mentions: 123 Fields:
    Translation:HumansAnimalsCells
  34. The hSK4 (KCNN4) isoform is the Ca2+-activated K+ channel (Gardos channel) in human red blood cells. Proc Natl Acad Sci U S A. 2003 Jun 10; 100(12):7366-71. Hoffman JF, Joiner W, Nehrke K, Potapova O, Foye K, Wickrema A. PMID: 12773623; PMCID: PMC165881.
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    Translation:HumansAnimalsCells
  35. Active K+ secretion through multiple KCa-type channels and regulation by IKCa channels in rat proximal colon. Am J Physiol Gastrointest Liver Physiol. 2003 Jul; 285(1):G185-96. Joiner WJ, Basavappa S, Vidyasagar S, Nehrke K, Krishnan S, Binder HJ, Boulpaep EL, Rajendran VM. PMID: 12606302.
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    Translation:AnimalsCells
  36. Targeted attenuation of electrical activity in Drosophila using a genetically modified K(+) channel. Neuron. 2001 Sep 13; 31(5):699-711. White BH, Osterwalder TP, Yoon KS, Joiner WJ, Whim MD, Kaczmarek LK, Keshishian H. PMID: 11567611.
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    Translation:AnimalsCells
  37. Calmodulin regulates assembly and trafficking of SK4/IK1 Ca2+-activated K+ channels. J Biol Chem. 2001 Oct 12; 276(41):37980-5. Joiner WJ, Khanna R, Schlichter LC, Kaczmarek LK. PMID: 11495911.
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    Translation:HumansAnimalsCells
  38. hSK4/hIK1, a calmodulin-binding KCa channel in human T lymphocytes. Roles in proliferation and volume regulation. J Biol Chem. 1999 May 21; 274(21):14838-49. Khanna R, Chang MC, Joiner WJ, Kaczmarek LK, Schlichter LC. PMID: 10329683.
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    Translation:HumansAnimalsCells
  39. Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits. Nat Neurosci. 1998 Oct; 1(6):462-9. Joiner WJ, Tang MD, Wang LY, Dworetzky SI, Boissard CG, Gan L, Gribkoff VK, Kaczmarek LK. PMID: 10196543.
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    Translation:AnimalsCells
  40. hSK4, a member of a novel subfamily of calcium-activated potassium channels. Proc Natl Acad Sci U S A. 1997 Sep 30; 94(20):11013-8. Joiner WJ, Wang LY, Tang MD, Kaczmarek LK. PMID: 9380751; PMCID: PMC23566.
    View in: PubMed Mentions: 140 Fields:
    Translation:HumansAnimalsCells
  41. A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem. Nature. 1995 Aug 24; 376(6542):690-5. Ketchum KA, Joiner WJ, Sellers AJ, Kaczmarek LK, Goldstein SA. PMID: 7651518.
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    Translation:AnimalsCells
  42. A characterization of the activating structural rearrangements in voltage-dependent Shaker K+ channels. Neuron. 1994 Feb; 12(2):301-15. McCormack K, Joiner WJ, Heinemann SH. PMID: 8110460.
    View in: PubMed Mentions: 68 Fields:
    Translation:AnimalsCells

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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