Bassem Al-Sady • UCSF Profiles (original) (raw)
- Histone 3 lysine 9 dimethylation by the G9a-GLP heterodimer requires intranucleosomal product reading. bioRxiv. 2026 Feb 05. Yousefi F, Simental EA, Du Y, Whedon S, Trnka MJ, Darling D, Jia S, Panning B, Cole PA, Halic M, Al-Sady B. PMID: 41648432; PMCID: PMC12871594.
View in: PubMed Mentions: - Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. Nucleic Acids Res. 2025 Nov 26; 53(22). Kennedy DR, Lemière J, Amine AAA, Martin EW, Tan C, Simental E, Braxton J, Maxwell RA, Al-Sady B. PMID: 41385327; PMCID: PMC12700098.
View in: PubMed Mentions: 1 Fields:
Translation:AnimalsCells - Discrete Subdomains Establish Epigenetic Diversity in Subtelomeric Heterochromatin. bioRxiv. 2025 Sep 25. Mazumder A, Cooper J, Goksal C, Khanduja JS, Joh RI, Groos JJ, Brockhausen RYJ, Kanoh J, Motamedi M, Finkelstein IJ, Al-Sady B, Braun S. PMID: 41040388; PMCID: PMC12485837.
View in: PubMed Mentions: - Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. bioRxiv. 2025 Sep 25. Kennedy DR, Lemière J, Amine AA, Martin EW, Tan C, Simental E, Braxton J, Maxwell RA, Al-Sady B. PMID: 39554105; PMCID: PMC11565791.
View in: PubMed Mentions: - The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate. Nat Cell Biol. 2025 Aug; 27(8):1311-1326. Marin HC, Allen C, Simental E, Martin EW, Panning B, Al-Sady B, Buchwalter A. PMID: 40696106; PMCID: PMC12339402.
View in: PubMed Mentions: 6 Fields:
Translation:AnimalsCells - A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin regulation. Nucleic Acids Res. 2024 Dec 11; 52(22):13665-13689. Muhammad A, Sarkadi Z, Mazumder A, Ait Saada A, van Emden T, Capella M, Fekete G, Suma Sreechakram VN, Al-Sady B, Lambert SAE, Papp B, Barrales RR, Braun S. PMID: 39565189; PMCID: PMC11662645.
View in: PubMed Mentions: Fields:
Translation:AnimalsCells - The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate. bioRxiv. 2024 Jul 11. Marin H, Simental E, Allen C, Martin E, Panning B, Al-Sady B, Buchwalter A. PMID: 39026839; PMCID: PMC11257442.
View in: PubMed Mentions: - A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin regulation. bioRxiv. 2024 Feb 15. Muhammad A, Sarkadi Z, van Emden T, Mazumder A, Capella M, Fekete G, Sreechakram VNS, Al-Sady B, Papp B, Barrales RR, Braun S. PMID: 38405799; PMCID: PMC10888830.
View in: PubMed Mentions: - Regulation of the heterochromatin spreading reaction by trans-acting factors. Open Biol. 2023 11; 13(11):230271. Hamali B, Amine AAA, Al-Sady B. PMID: 37935357; PMCID: PMC10645111.
View in: PubMed Mentions: 5 Fields:
Translation:Cells - A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading. Genetics. 2023 08 09; 224(4). Challal D, Menant A, Goksal C, Leroy E, Al-Sady B, Rougemaille M. PMID: 37279920; PMCID: PMC10411572.
View in: PubMed Mentions: 2 Fields:
Translation:AnimalsCells - Proteome effects of genome-wide single gene perturbations. Nat Commun. 2022 10 18; 13(1):6153. Öztürk M, Freiwald A, Cartano J, Schmitt R, Dejung M, Luck K, Al-Sady B, Braun S, Levin M, Butter F. PMID: 36257942; PMCID: PMC9579165.
View in: PubMed Mentions: 11 Fields:
Translation:HumansAnimals - Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction. PLoS Genet. 2022 05; 18(5):e1010201. Greenstein RA, Ng H, Barrales RR, Tan C, Braun S, Al-Sady B. PMID: 35584134; PMCID: PMC9154106.
View in: PubMed Mentions: 10 Fields:
Translation:AnimalsCells - The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states. Cell Rep. 2021 11 02; 37(5):109944. Murawska M, Greenstein RA, Schauer T, Olsen KCF, Ng H, Ladurner AG, Al-Sady B, Braun S. PMID: 34731638; PMCID: PMC8608617.
View in: PubMed Mentions: 21 Fields:
Translation:AnimalsCells - Heterodimerization of H3K9 histone methyltransferases G9a and GLP activates methyl reading and writing capabilities. J Biol Chem. 2021 11; 297(5):101276. Sanchez NA, Kallweit LM, Trnka MJ, Clemmer CL, Al-Sady B. PMID: 34619147; PMCID: PMC8564726.
View in: PubMed Mentions: 15 Fields:
Translation:HumansCells - Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability. Genes Dev. 2020 01 01; 34(1-2):99-117. Greenstein RA, Barrales RR, Sanchez NA, Bisanz JE, Braun S, Al-Sady B. PMID: 31805521; PMCID: PMC6938669.
View in: PubMed Mentions: 9 Fields:
Translation:AnimalsCells - Epigenetic fates of gene silencing established by heterochromatin spreading in cell identity and genome stability. Curr Genet. 2019 Apr; 65(2):423-428. Greenstein RA, Al-Sady B. PMID: 30390097; PMCID: PMC6452905.
View in: PubMed Mentions: 6 Fields:
Translation:HumansAnimalsCells - Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability. Elife. 2018 07 18; 7. Greenstein RA, Jones SK, Spivey EC, Rybarski JR, Finkelstein IJ, Al-Sady B. PMID: 30020075; PMCID: PMC6070336.
View in: PubMed Mentions: 23 Fields:
Translation:AnimalsCells - Chromatin Curtains: A Single-Molecule Method for Visualizing Histone Marks on Chromatin Substrates In Vitro. Biophysical Journal. 2018 Feb 1; 114(3):254a. Jensen JL, Al-Sady AB, Redding RS. .
View in: Publisher Site Mentions: - Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics. PLoS One. 2016; 11(8):e0159292. Al-Sady B, Greenstein RA, El-Samad HJ, Braun S, Madhani HD. PMID: 27479698; PMCID: PMC4968791.
View in: PubMed Mentions: 10 Fields:
Translation:AnimalsCells - Molecular convergence of clock and photosensory pathways through PIF3-TOC1 interaction and co-occupancy of target promoters. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):4870-5. Soy J, Leivar P, González-Schain N, Martín G, Diaz C, Sentandreu M, Al-Sady B, Quail PH, Monte E. PMID: 27071129; PMCID: PMC4855547.
View in: PubMed Mentions: 74 Fields:
Translation:AnimalsCells - Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe. G3 (Bethesda). 2015 May 08; 5(7):1453-61. Garcia JF, Al-Sady B, Madhani HD. PMID: 25957277; PMCID: PMC4502379.
View in: PubMed Mentions: 9 Fields:
Translation:AnimalsCells - Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread. Mol Cell. 2013 Jul 11; 51(1):80-91. Al-Sady B, Madhani HD, Narlikar GJ. PMID: 23849629; PMCID: PMC3752401.
View in: PubMed Mentions: 92 Fields:
Translation:AnimalsCells - Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase. Chem Biol. 2013 Apr 18; 20(4):494-9. Shiau C, Trnka MJ, Bozicevic A, Ortiz Torres I, Al-Sady B, Burlingame AL, Narlikar GJ, Fujimori DG. PMID: 23601638; PMCID: PMC3704229.
View in: PubMed Mentions: 16 Fields:
Translation:HumansCells - Dynamic antagonism between phytochromes and PIF family basic helix-loop-helix factors induces selective reciprocal responses to light and shade in a rapidly responsive transcriptional network in Arabidopsis. Plant Cell. 2012 Apr; 24(4):1398-419. Leivar P, Tepperman JM, Cohn MM, Monte E, Al-Sady B, Erickson E, Quail PH. PMID: 22517317; PMCID: PMC3398554.
View in: PubMed Mentions: 116 Fields:
Translation:AnimalsCells - Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Mol Cell. 2011 Jan 07; 41(1):67-81. Canzio D, Chang EY, Shankar S, Kuchenbecker KM, Simon MD, Madhani HD, Narlikar GJ, Al-Sady B. PMID: 21211724; PMCID: PMC3752404.
View in: PubMed Mentions: 198 Fields:
Translation:Cells - The Arabidopsis phytochrome-interacting factor PIF7, together with PIF3 and PIF4, regulates responses to prolonged red light by modulating phyB levels. Plant Cell. 2008 Feb; 20(2):337-52. Leivar P, Monte E, Al-Sady B, Carle C, Storer A, Alonso JM, Ecker JR, Quail PH. PMID: 18252845; PMCID: PMC2276449.
View in: PubMed Mentions: 215 Fields:
Translation:AnimalsCells - Mechanistic duality of transcription factor function in phytochrome signaling. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):2232-7. Al-Sady B, Kikis EA, Monte E, Quail PH. PMID: 18245378; PMCID: PMC2538903.
View in: PubMed Mentions: 69 Fields:
Translation:AnimalsCells - Out of the dark: how the PIFs are unmasking a dual temporal mechanism of phytochrome signalling. J Exp Bot. 2007; 58(12):3125-33. Monte E, Al-Sady B, Leivar P, Quail PH. PMID: 17855731.
View in: PubMed Mentions: 34 Fields:
Translation:Cells - Photoactivated phytochrome induces rapid PIF3 phosphorylation prior to proteasome-mediated degradation. Mol Cell. 2006 Aug 04; 23(3):439-46. Al-Sady B, Ni W, Kircher S, Schäfer E, Quail PH. PMID: 16885032.
View in: PubMed Mentions: 278 Fields:
Translation:AnimalsCells - The phytochrome-interacting transcription factor, PIF3, acts early, selectively, and positively in light-induced chloroplast development. Proc Natl Acad Sci U S A. 2004 Nov 16; 101(46):16091-8. Monte E, Tepperman JM, Al-Sady B, Kaczorowski KA, Alonso JM, Ecker JR, Li X, Zhang Y, Quail PH. PMID: 15505214; PMCID: PMC528976.
View in: PubMed Mentions: 151 Fields:
Translation:AnimalsCells - A novel molecular recognition motif necessary for targeting photoactivated phytochrome signaling to specific basic helix-loop-helix transcription factors. Plant Cell. 2004 Nov; 16(11):3033-44. Khanna R, Huq E, Kikis EA, Al-Sady B, Lanzatella C, Quail PH. PMID: 15486100; PMCID: PMC527196.
View in: PubMed Mentions: 182 Fields:
Translation:AnimalsCells - Phytochrome-interacting factor 1 is a critical bHLH regulator of chlorophyll biosynthesis. Science. 2004 Sep 24; 305(5692):1937-41. Huq E, Al-Sady B, Hudson M, Kim C, Apel K, Quail PH. PMID: 15448264.
View in: PubMed Mentions: 229 Fields:
Translation:AnimalsCells - Nuclear translocation of the photoreceptor phytochrome B is necessary for its biological function in seedling photomorphogenesis. Plant J. 2003 Sep; 35(5):660-4. Huq E, Al-Sady B, Quail PH. PMID: 12940958.
View in: PubMed Mentions: 52 Fields:
Translation:AnimalsCells
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This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
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