Matthew Kutys • UCSF Profiles (original) (raw)
- The Notch1 intracellular domain orchestrates mechanotransduction of fluid shear stress. Life Sci Alliance. 2026 Apr; 9(4). Singh T, Jacobs KA, Polacheck WJ, Kutys ML. PMID: 41644301; PMCID: PMC12877406.
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Translation:HumansAnimalsCells - The Notch1 intracellular domain orchestrates mechanotransduction of fluid shear stress. bioRxiv. 2025 Jul 14. Singh T, Jacobs KA, Polacheck WJ, Kutys ML. PMID: 40791532; PMCID: PMC12338707.
View in: PubMed Mentions: - Perivascular matrix densification dysregulates angiogenesis and activates pro-inflammatory endothelial cells. bioRxiv. 2025 May 25. Xia J, Wang WY, Jacobs KA, Lin D, Jarman EH, Matera DL, Loesel K, Davidson CD, Hiraki HL, Tan X, Shikanov EH, Kent RN, Parent C, Fan X, Shikanov A, Kutys ML, Baker BM. PMID: 40475473; PMCID: PMC12139983.
View in: PubMed Mentions: - Quantitative comparison of fluorescent proteins using protein nanocages in live cells. J Cell Sci. 2025 May 15; 138(10). Viola G, Ibrahim YW, Jacobs KA, Lemière J, Kutys ML, Wittmann T. PMID: 40326462; PMCID: PMC12148025.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimalsCells - Editorial overview: Cell dynamics across biological length scales. Curr Opin Cell Biol. 2025 Jun; 94:102489. Kutys ML, Grosse R. PMID: 40037053.
View in: PubMed Mentions: Fields: - Doublecortin reinforces microtubules to promote growth cone advance in soft environments. Curr Biol. 2024 Dec 16; 34(24):5822-5832.e5. Dema A, Charafeddine RA, van Haren J, Rahgozar S, Viola G, Jacobs KA, Kutys ML, Wittmann T. PMID: 39626666; PMCID: PMC11740832.
View in: PubMed Mentions: 6 Fields:
Translation:HumansCells - Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain. Nat Neurosci. 2024 Nov; 27(11):2115-2129. Chen J, Crouch EE, Zawadzki ME, Jacobs KA, Mayo LN, Choi JJ, Lin PY, Shaikh S, Tsui J, Gonzalez-Granero S, Waller S, Kelekar A, Kang G, Valenzuela EJ, Birrueta JO, Diafos LN, Wedderburn-Pugh K, Di Marco B, Xia W, Han CZ, Coufal NG, Glass CK, Fancy SPJ, Alfonso J, Kriegstein AR, Oldham MC, Garcia-Verdugo JM, Kutys ML, Lehtinen MK, Combes AJ, Huang EJ. PMID: 39349662; PMCID: PMC11537974.
View in: PubMed Mentions: 7 Fields:
Translation:HumansAnimalsCells - Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells. Elife. 2024 Sep 25; 13. Meyer NP, Singh T, Kutys ML, Nystul TG, Barber DL. PMID: 39319536; PMCID: PMC11509671.
View in: PubMed Mentions: 3 Fields:
Translation:HumansCells - Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion. J Cell Biol. 2023 12 04; 222(12). White MJ, Jacobs KA, Singh T, Mayo LN, Lin A, Chen CS, Jun YW, Kutys ML. PMID: 37796194; PMCID: PMC10555887.
View in: PubMed Mentions: 4 Fields:
Translation:HumansCells - A 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex. Proc Natl Acad Sci U S A. 2023 10 10; 120(41):e2308941120. Lee E, Chan SL, Lee Y, Polacheck WJ, Kwak S, Wen A, Nguyen DT, Kutys ML, Alimperti S, Kolarzyk AM, Kwak TJ, Eyckmans J, Bielenberg DR, Chen H, Chen CS. PMID: 37782785; PMCID: PMC10576061.
View in: PubMed Mentions: 7 Fields:
Translation:AnimalsCells - 'Chip'-ing away at morphogenesis - application of organ-on-chip technologies to study tissue morphogenesis. J Cell Sci. 2023 10 01; 136(19). White MJ, Singh T, Wang E, Smith Q, Kutys ML. PMID: 37795818; PMCID: PMC10565497.
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Translation:Humans - A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer. Nat Commun. 2023 06 15; 14(1):3561. Stashko C, Hayward MK, Northey JJ, Pearson N, Ironside AJ, Lakins JN, Oria R, Goyette MA, Mayo L, Russnes HG, Hwang ES, Kutys ML, Polyak K, Weaver VM. PMID: 37322009; PMCID: PMC10272194.
View in: PubMed Mentions: 20 Fields:
Translation:Humans - Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. Cell Syst. 2023 04 19; 14(4):252-257. Adler FR, Anderson ARA, Bhushan A, Bogdan P, Bravo-Cordero JJ, Brock A, Chen Y, Cukierman E, DelGiorno KE, Denis GV, Ferrall-Fairbanks MC, Gartner ZJ, Germain RN, Gordon DM, Hunter G, Jolly MK, Karacosta LG, Mythreye K, Katira P, Kulkarni RP, Kutys ML, Lander AD, Laughney AM, Levine H, Lou E, Lowenstein PR, Masters KS, Pe'er D, Peyton SR, Platt MO, Purvis JE, Quon G, Richer JK, Riddle NC, Rodriguez A, Snyder JC, Lee Szeto G, Tomlin CJ, Yanai I, Zervantonakis IK, Dueck H. PMID: 37080161; PMCID: PMC10760508.
View in: PubMed Mentions: 4 Fields:
Translation:Humans - Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation. Sci Adv. 2023 02 15; 9(7):eade8939. Aw WY, Cho C, Wang H, Cooper AH, Doherty EL, Rocco D, Huang SA, Kubik S, Whitworth CP, Armstrong R, Hickey AJ, Griffith B, Kutys ML, Blatt J, Polacheck WJ. PMID: 36791204; PMCID: PMC9931220.
View in: PubMed Mentions: 10 Fields:
Translation:HumansCells - Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion. bioRxiv. 2023 Jan 23. White MJ, Jacobs KA, Singh T, Kutys ML. PMID: 36747830; PMCID: PMC9900753.
View in: PubMed Mentions: - Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling. Nat Cell Biol. 2022 12; 24(12):1739-1753. Kwak M, Southard KM, Kim WR, Lin A, Kim NH, Gopalappa R, Lee HJ, An M, Choi SH, Jung Y, Noh K, Farlow J, Georgakopoulos A, Robakis NK, Kang MK, Kutys ML, Seo D, Kim HH, Kim YH, Cheon J, Gartner ZJ, Jun YW. PMID: 36456828; PMCID: PMC10665132.
View in: PubMed Mentions: 11 Fields: - Conversation before crossing: dissecting metastatic tumor-vascular interactions in microphysiological systems. Am J Physiol Cell Physiol. 2022 11 01; 323(5):C1333-C1344. Mayo LN, Kutys ML. PMID: 36121131; PMCID: PMC9602802.
View in: PubMed Mentions: 3 Fields:
Translation:HumansCells - 3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain. Dev Cell. 2021 03 22; 56(6):826-841.e4. Doyle AD, Sykora DJ, Pacheco GG, Kutys ML, Yamada KM. PMID: 33705692; PMCID: PMC8082573.
View in: PubMed Mentions: 51 Fields:
Translation:HumansCells - Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform. Nat Commun. 2020 07 06; 11(1):3377. Kutys ML, Polacheck WJ, Welch MK, Gagnon KA, Koorman T, Kim S, Li L, McClatchey AI, Chen CS. PMID: 32632100; PMCID: PMC7338408.
View in: PubMed Mentions: 31 Fields:
Translation:HumansCells - Microfabricated blood vessels for modeling the vascular transport barrier. Nat Protoc. 2019 05; 14(5):1425-1454. Polacheck WJ, Kutys ML, Tefft JB, Chen CS. PMID: 30953042; PMCID: PMC7046311.
View in: PubMed Mentions: 112 Fields:
Translation:HumansCells - Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration. APL Bioeng. 2018 Dec; 2(4):046107. Wang WY, Pearson AT, Kutys ML, Choi CK, Wozniak MA, Baker BM, Chen CS. PMID: 31069329; PMCID: PMC6481732.
View in: PubMed Mentions: 58 - Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. Dev Cell. 2018 01 08; 44(1):87-96.e5. Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS. PMID: 29316444; PMCID: PMC6421364.
View in: PubMed Mentions: 89 Fields:
Translation:HumansCells - A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. 2017 12 14; 552(7684):258-262. Polacheck WJ, Kutys ML, Yang J, Eyckmans J, Wu Y, Vasavada H, Hirschi KK, Chen CS. PMID: 29160307; PMCID: PMC5730479.
View in: PubMed Mentions: 206 Fields:
Translation:HumansAnimalsCells - Forces and mechanotransduction in 3D vascular biology. Curr Opin Cell Biol. 2016 10; 42:73-79. Kutys ML, Chen CS. PMID: 27209346; PMCID: PMC5064809.
View in: PubMed Mentions: 36 Fields:
Translation:HumansAnimalsCells - Rho GEFs and GAPs: emerging integrators of extracellular matrix signaling. Small GTPases. 2015; 6(1):16-9. Kutys ML, Yamada KM. PMID: 25862162; PMCID: PMC4601481.
View in: PubMed Mentions: 9 Fields:
Translation:HumansCells - An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration. Nat Cell Biol. 2014 Sep; 16(9):909-17. Kutys ML, Yamada KM. PMID: 25150978; PMCID: PMC4150836.
View in: PubMed Mentions: 56 Fields:
Translation:HumansCells - Dimensions in cell migration. Curr Opin Cell Biol. 2013 Oct; 25(5):642-9. Doyle AD, Petrie RJ, Kutys ML, Yamada KM. PMID: 23850350; PMCID: PMC3758466.
View in: PubMed Mentions: 94 Fields:
Translation:HumansAnimalsCells - Regulation of cell adhesion and migration by cell-derived matrices. Exp Cell Res. 2013 Oct 01; 319(16):2434-9. Kutys ML, Doyle AD, Yamada KM. PMID: 23751565; PMCID: PMC3780580.
View in: PubMed Mentions: 28 Fields:
Translation:HumansAnimalsCells - Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration. J Cell Sci. 2013 Jun 15; 126(Pt 12):2617-28. Li X, Zhou Q, Sunkara M, Kutys ML, Wu Z, Rychahou P, Morris AJ, Zhu H, Evers BM, Huang C. PMID: 23572508; PMCID: PMC3687698.
View in: PubMed Mentions: 47 Fields:
Translation:HumansAnimalsCells - Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics. J Cell Sci. 2012 May 01; 125(Pt 9):2244-56. Doyle AD, Kutys ML, Conti MA, Matsumoto K, Adelstein RS, Yamada KM. PMID: 22328520; PMCID: PMC3367941.
View in: PubMed Mentions: 68 Fields:
Translation:AnimalsCells - Monte Carlo analysis of neck linker extension in kinesin molecular motors. PLoS Comput Biol. 2010 Nov 04; 6(11):e1000980. Kutys ML, Fricks J, Hancock WO. PMID: 21079666; PMCID: PMC2973807.
View in: PubMed Mentions: 18 Fields:
Translation:Cells
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
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