Paul Ogongo • UCSF Profiles (original) (raw)

  1. Rare variable M. tuberculosis antigens induce predominant Th17 responses in human infection. JCI Insight. 2026 Jan 27. Ogongo P, Wassie L, Tran A, Columbus D, Huffaker J, Sharling L, Ouma G, Ouma SG, Bobosha K, Lindestam Arlehamn CS, Gandhi NR, Auld SC, Rengarajan J, Day CL, Queiroz A, Araújo-Pereira M, Fukutani E, Andrade BB, Altman JD, Blumberg HM, Ernst JD. PMID: 41591832.
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  2. Evolution of the tuberculin skin test reveals generalisable Mtb-reactive T cell metaclones. Nat Commun. 2026 01 21; 17(1). Turner CT, Tiffeau-Mayer A, Rosenheim J, Chandran A, Saxena R, Zhang P, Jiang J, Berkeley M, Pang F, Uddin I, Nageswaran G, Byrne S, Karthikeyan A, Smidt W, Ogongo P, Byng-Maddick R, Capocci S, Lipman M, Kunst H, Lozewicz S, Ramsuran V, Pollara G, Knight JC, Leslie A, Chain BM, Noursadeghi M. PMID: 41565657; PMCID: PMC12923891.
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    Translation:HumansCells
  3. Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens. Sci Transl Med. 2025 Nov 05; 17(823):eadw9184. Leddy O, Ogongo P, Huffaker J, Gan M, Milligan R, Mahmud S, Ni HM, Yuki Y, Bobosha K, Wassie L, Carrington M, Liu Q, Ernst JD, White FM, Bryson BD. PMID: 41191777.
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  4. Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay. Viruses. 2025 Sep 16; 17(9). Waweru G, Nyakundi R, Kutima B, Owuor S, Konyino G, Gitonga J, Lugano D, Maina A, Musyoki J, Ochola L, Omondi M, Kariuki CK, Ogongo P, Mwachari C, Shee F, Agoti C, Sande C, Uyoga S, Kagucia E, Agweyu A, Bejon P, Scott JAG, Warimwe GM, Ochola-Oyier LI, Nyagwange J. PMID: 41012675; PMCID: PMC12474121.
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    Translation:HumansCells
  5. Increased circulating Th17 cells and altered CD4 T cell maturation and differentiation in active tuberculosis with type 2 diabetes: a pilot study. Frontiers in Immunology. 2025 Sep 9; 16:1637868. Ogongo OP, Martinez-Lopez MY, Tran TA, Arlehamn AC, Sette SA, Dominguez-Trejo DI, Garza GL, Cruz-Gonzalez CA, Loera-Salazar LR, Rodríguez-Herrera RJ, Aguillón-Durán AG, Garcia-Oropesa GE, Ernst EJ, Restrepo RB. .
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  6. Driving innovation from discovery to access: Meeting report of the 7 th Global Forum on TB Vaccines (8-10 October 2024, Rio de Janeiro, Brazil). Gates Open Res. 2025; 9:65. Palmer S, Clark RA, Connell BJ, Muwanga VM, Coelho A, Ogongo P, Young C. PMID: 40896556; PMCID: PMC12391588.
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    Translation:Humans
  7. Application of microphysiological systems to unravel the mechanisms of schistosomiasis egg extravasation. Front Cell Infect Microbiol. 2025; 15:1521265. Alfred MO, Ochola L, Okeyo K, Bae E, Ogongo P, Odongo D, Njaanake K, Robinson JP. PMID: 40041145; PMCID: PMC11876127.
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    Translation:HumansAnimalsCells
  8. Immunopeptidomics informs discovery and delivery of Mycobacterium tuberculosis MHC-II antigens for vaccine design. bioRxiv. 2024 Oct 03. Leddy O, Ogongo P, Huffaker J, Gan M, Milligan R, Mahmud S, Yuki Y, Bobosha K, Wassie L, Carrington M, Liu Q, Ernst JD, White FM, Bryson BD. PMID: 41031036; PMCID: PMC12478359.
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  9. A broader evaluation of vaccine-induced T cell immunity against tuberculosis. Frontiers in Tuberculosis. 2024 Jul 19; 2:1435344. Ogongo OP. .
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  10. B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles. Commun Biol. 2024 05 16; 7(1):584. Krause R, Ogongo P, Tezera L, Ahmed M, Mbano I, Chambers M, Ngoepe A, Magnoumba M, Muema D, Karim F, Khan K, Lumamba K, Nargan K, Madansein R, Steyn A, Shalek AK, Elkington P, Leslie A. PMID: 38755239; PMCID: PMC11099031.
    View in: PubMed Mentions: 15 Translation:HumansCells
  11. High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen. Front Immunol. 2024; 15:1378040. Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. PMID: 38698866; PMCID: PMC11064812.
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    Translation:HumansCells
  12. Rare Variable M. tuberculosis Antigens induce predominant Th17 responses in human infection. bioRxiv. 2024 Mar 06. Ogongo P, Wassie L, Tran A, Columbus D, Sharling L, Ouma G, Ouma SG, Bobosha K, Lindestam Arlehamn CS, Gandhi NR, Auld SC, Rengarajan J, Day CL, Altman JD, Blumberg HM, Ernst JD, TBRU ASTRa Study Group. PMID: 38496518; PMCID: PMC10942433.
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  13. Recognition and control of Mycobacterium tuberculosis-infected cells: from basics to the clinic: a NIAID/WGNV workshop report 2023. 2023. Carly C Young, Mbali N. Mkhonza, Paul Ogongo. .
  14. Finding antigens for TB vaccines: the good, the bad and the useless. Nat Med. 2023 01; 29(1):35-36. Ogongo P, Ernst JD. PMID: 36604539; PMCID: PMC9877171.
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    Translation:HumansCells
  15. Do vaginal microbicides reduce the risk of HIV acquisition in women? Pan Afr Med J. 2022; 43:96. Obiero JA, Ogongo P, Mwethera PG, Wiysonge CS. PMID: 36660088; PMCID: PMC9816879.
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    Translation:Humans
  16. The Road to Elimination: Current State of Schistosomiasis Research and Progress Towards the End Game. Front Immunol. 2022; 13:846108. Ogongo P, Nyakundi RK, Chege GK, Ochola L. PMID: 35592327; PMCID: PMC9112563.
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    Translation:Animals
  17. Acquired Clinical Immunity to Malaria in Nonhuman Primates Coinfected with Schistosoma and Plasmodium Parasites. Infect Immun. 2022 02 17; 90(2):e0046421. Nyakundi RK, Hau J, Ogongo P, Nyamongo O, Jeneby M, Akinyi M, Mulei I, Nyundo F, Farah I, Malhotra I, Ozwara H, King CL, Kariuki T. PMID: 34871040; PMCID: PMC8853685.
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    Translation:Animals
  18. Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire. Sci Transl Med. 2021 12; 13(622):eabe7430. von Borstel A, Chevour P, Arsovski D, Krol JMM, Howson LJ, Berry AA, Day CL, Ogongo P, Ernst JD, Nomicos EYH, Boddey JA, Giles EM, Rossjohn J, Traore B, Lyke KE, Williamson KC, Crompton PD, Davey MS. PMID: 34851691; PMCID: PMC9291638.
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    Translation:HumansAnimalsCells
  19. A Framework to Identify Antigen-Expanded T Cell Receptor Clusters Within Complex Repertoires. Front Immunol. 2021; 12:735584. Ceglia V, Kelley EJ, Boyle AS, Zurawski S, Mead HL, Harms CE, Blanck JP, Flamar AL, Kirschman JH, Ogongo P, Ernst JD, Levy Y, Zurawski G, Altin JA. PMID: 34917073; PMCID: PMC8670329.
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    Translation:HumansCells
  20. Performance Evaluation of Lateral Flow Assays for Coronavirus Disease-19 Serology. Clin Lab Med. 2022 03; 42(1):31-56. Ochola L, Ogongo P, Mungai S, Gitaka J, Suliman S. PMID: 35153047; PMCID: PMC8563367.
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    Translation:HumansCellsPHPublic Health
  21. Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung. J Clin Invest. 2021 05 17; 131(10). Ogongo P, Tezera LB, Ardain A, Nhamoyebonde S, Ramsuran D, Singh A, Ng'oepe A, Karim F, Naidoo T, Khan K, Dullabh KJ, Fehlings M, Lee BH, Nardin A, Lindestam Arlehamn CS, Sette A, Behar SM, Steyn AJ, Madansein R, Kløverpris HN, Elkington PT, Leslie A. PMID: 33848273; PMCID: PMC8121523.
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    Translation:HumansCellsCTClinical Trials
  22. Topical microbicides for preventing sexually transmitted infections. Cochrane Database Syst Rev. 2021 03 13; 3:CD007961. Obiero J, Ogongo P, Mwethera PG, Wiysonge CS. PMID: 33719075; PMCID: PMC8092571.
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    Translation:HumansAnimals
  23. Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection. Front Immunol. 2020; 11:579743. Magnoumba M, Singh A, Ogongo P, Roider J, Asowata O, Fehlings M, Karim F, Ndung'u T, Anderson F, Leslie A, Kløverpris H. PMID: 33117384; PMCID: PMC7561384.
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    Translation:HumansCells
  24. Single cell transcriptomics of the T cell response to Mycobacterium Tuberculosis reveals phenotypic diversity within and between infected individuals. 2020; (204):(1_Supplement): 225.21.. Junghwa Choi Kirschman; Paul Ogongo; Joel Ernst; John Altin. . View Publication.
  25. Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α. Elife. 2020 02 24; 9. Tezera LB, Bielecka MK, Ogongo P, Walker NF, Ellis M, Garay-Baquero DJ, Thomas K, Reichmann MT, Johnston DA, Wilkinson KA, Ahmed M, Jogai S, Jayasinghe SN, Wilkinson RJ, Mansour S, Thomas GJ, Ottensmeier CH, Leslie A, Elkington PT. PMID: 32091388; PMCID: PMC7058383.
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    Translation:HumansCells
  26. Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs. J Clin Invest. 2020 01 02; 130(1):214-230. Ogongo P, Steyn AJ, Karim F, Dullabh KJ, Awala I, Madansein R, Leslie A, Behar SM. PMID: 31763997; PMCID: PMC6934215.
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    Translation:HumansCells
  27. Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. 2019 Aug; 572(7768):E10. Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, Ulland TK, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. PMID: 31337923.
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  28. Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children. Front Immunol. 2019; 10:1497. Roider J, Porterfield JZ, Ogongo P, Muenchhoff M, Adland E, Groll A, Morris L, Moore PL, Ndung'u T, Kløverpris H, Goulder PJR, Leslie A. PMID: 31333650; PMCID: PMC6615198.
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    Translation:HumansCells
  29. Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. 2019 06; 570(7762):528-532. Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. PMID: 31168092; PMCID: PMC6626542.
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    Translation:HumansAnimalsCells
  30. Lung Tissue Resident Memory T-Cells in the Immune Response to Mycobacterium tuberculosis. Front Immunol. 2019; 10:992. Ogongo P, Porterfield JZ, Leslie A. PMID: 31130965; PMCID: PMC6510113.
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    Translation:HumansAnimalsCells
  31. Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells. Front Immunol. 2018; 9:2539. Attaf M, Malik A, Severinsen MC, Roider J, Ogongo P, Buus S, Ndung'u T, Leslie A, Kløverpris HN, Matthews PC, Sewell AK, Goulder P. PMID: 30487790; PMCID: PMC6246681.
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    Translation:HumansCells
  32. Nifuratel‐Nystatin combination for the treatment of mixed infections of bacterial vaginosis, vulvovaginal candidiasis, and trichomonal vaginitis. Cochrane Database Systematic Reviews. 2018; (4). Jael Obrero, Stephen Rulisa, Paul Ogongo and Charles S Wiysonge. . [View Publication](http://DOI: 10.1002/14651858.CD013012).
  33. Diagnosis of schistosomiasis mansoni: an evaluation of existing methods and research towards single worm pair detection. Parasitology. 2018 09; 145(11):1355-1366. Ogongo P, Kariuki TM, Wilson RA. PMID: 29506583.
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    Translation:HumansAnimals
  34. Protective Potential of Antioxidant Enzymes as Vaccines for Schistosomiasis in a Non-Human Primate Model. Front Immunol. 2015; 6:273. Carvalho-Queiroz C, Nyakundi R, Ogongo P, Rikoi H, Egilmez NK, Farah IO, Kariuki TM, LoVerde PT. PMID: 26082781; PMCID: PMC4451692.
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  35. International Journal of Infectious Diseases. Identification and evaluation of Schistosoma mansoni proteins as diagnostic targets for schistosomiasis. 2014; 21(365):SUPPLEMENT 1. Paul Ogongo. . View Publication.

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