Robert Edwards • UCSF Profiles (original) (raw)

  1. Synaptic vesicles that store monoamines and glutamate differ in protein composition. bioRxiv. 2025 Jun 10. Asmerian H, Diaz AJ, Xu H, Oses-Prieto JA, Alberts J, Sanetra A, Gnanabharathi B, Carr N, Burlingame AL, Edwards RH, Silm K. PMID: 40661501; PMCID: PMC12258905.
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  2. Substrate recognition and allosteric regulation of synaptic vesicle glutamate transporter VGLUT2. Nat Struct Mol Biol. 2025 Aug; 32(8):1479-1487. Li F, Eriksen J, Oses-Prieto JA, Gomez YK, Xu H, Hareendranath S, Das P, Finer-Moore J, Nguyen P, Bowen A, Nelson A, Burlingame A, Grabe M, Stroud RM, Edwards RH. PMID: 40461871; PMCID: PMC12702523.
    View in: PubMed Mentions: Fields:
    Translation:AnimalsCells
  3. Research Priorities on the Role of α-Synuclein in Parkinson's Disease Pathogenesis. Mov Disord. 2024 Oct; 39(10):1663-1678. Burré J, Edwards RH, Halliday G, Lang AE, Lashuel HA, Melki R, Murayama S, Outeiro TF, Papa SM, Stefanis L, Woerman AL, Surmeier DJ, Kalia LV, Takahashi R, MDS Scientific Issues Committee. PMID: 38946200; PMCID: PMC11808831.
    View in: PubMed Mentions: 9 Fields:
    Translation:HumansAnimals
  4. Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome. Nat Commun. 2024 Jun 25; 15(1):5388. Zhao B, Cao Z, Zheng Y, Nguyen P, Bowen A, Edwards RH, Stroud RM, Zhou Y, Van Lookeren Campagne M, Li F. PMID: 38918376; PMCID: PMC11199644.
    View in: PubMed Mentions: 2 Fields:
    Translation:HumansCells
  5. The role of α-synuclein in exocytosis. Exp Neurol. 2024 Mar; 373:114668. Runwal GM, Edwards RH. PMID: 38147972.
    View in: PubMed Mentions: 4 Fields:
    Translation:Humans
  6. Adaptor protein-3 produces synaptic vesicles that release phasic dopamine. Proc Natl Acad Sci U S A. 2023 10 17; 120(42):e2309843120. Jain S, Yee AG, Maas J, Gierok S, Xu H, Stansil J, Eriksen J, Nelson AB, Silm K, Ford CP, Edwards RH. PMID: 37812725; PMCID: PMC10589613.
    View in: PubMed Mentions: 10 Fields:
    Translation:Cells
  7. Adaptor protein AP-3 produces synaptic vesicles that release at high frequency by recruiting phospholipid flippase ATP8A1. Nat Neurosci. 2023 10; 26(10):1685-1700. Xu H, Oses-Prieto JA, Khvotchev M, Jain S, Liang J, Burlingame A, Edwards RH. PMID: 37723322.
    View in: PubMed Mentions: 5 Fields:
    Translation:AnimalsCells
  8. Adaptor Protein-3 Produces Synaptic Vesicles that Release Phasic Dopamine. bioRxiv. 2023 Aug 08. Jain S, Yee AG, Maas J, Gierok S, Xu H, Stansil J, Eriksen J, Nelson A, Silm K, Ford CP, Edwards RH. PMID: 37609166; PMCID: PMC10441354.
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  9. Synuclein phosphorylation: pathogenic or physiologic? NPJ Parkinsons Dis. 2023 Mar 28; 9(1):47. Kontaxi C, Edwards RH. PMID: 36977661; PMCID: PMC10050171.
    View in: PubMed Mentions: 5
  10. Substrate recognition and proton coupling by a bacterial member of solute carrier family 17. J Biol Chem. 2023 05; 299(5):104646. Batarni S, Nayak N, Chang A, Li F, Hareendranath S, Zhou L, Xu H, Stroud R, Eriksen J, Edwards RH. PMID: 36965620; PMCID: PMC10149257.
    View in: PubMed Mentions: 2 Fields:
    Translation:Cells
  11. High-speed imaging reveals the bimodal nature of dense core vesicle exocytosis. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2214897120. Zhang P, Rumschitzki D, Edwards RH. PMID: 36574702; PMCID: PMC9910497.
    View in: PubMed Mentions: 4 Fields:
    Translation:AnimalsCells
  12. Diversity of function and mechanism in a family of organic anion transporters. Curr Opin Struct Biol. 2022 08; 75:102399. Li F, Eriksen J, Finer-Moore J, Stroud RM, Edwards RH. PMID: 35660266; PMCID: PMC9884543.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
  13. Input-specific control of interneuron numbers in nascent striatal networks. Proc Natl Acad Sci U S A. 2022 05 17; 119(20):e2118430119. Sreenivasan V, Serafeimidou-Pouliou E, Exposito-Alonso D, Bercsenyi K, Bernard C, Bae SE, Oozeer F, Hanusz-Godoy A, Edwards RH, Marín O. PMID: 35533272; PMCID: PMC9171775.
    View in: PubMed Mentions: 9 Fields:
    Translation:Cells
  14. SNX5 targets a monoamine transporter to the TGN for assembly into dense core vesicles by AP-3. J Cell Biol. 2022 05 02; 221(5). Xu H, Chang F, Jain S, Heller BA, Han X, Liu Y, Edwards RH. PMID: 35426896; PMCID: PMC9016777.
    View in: PubMed Mentions: 6 Fields:
    Translation:Cells
  15. Whole Endosome Recording of Vesicular Neurotransmitter Transporter Currents. Methods Mol Biol. 2022; 2417:29-44. Chang R, Edwards RH. PMID: 35099789.
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    Translation:AnimalsCells
  16. Allosteric Inhibition of a Vesicular Glutamate Transporter by an Isoform-Specific Antibody. Biochemistry. 2021 08 17; 60(32):2463-2470. Eriksen J, Li F, Stroud RM, Edwards RH. PMID: 34319067; PMCID: PMC8823281.
    View in: PubMed Mentions: 2 Fields:
    Translation:HumansAnimalsCells
  17. The Membrane Interactions of Synuclein: Physiology and Pathology. Annu Rev Pathol. 2021 01 24; 16:465-485. Runwal G, Edwards RH. PMID: 33497259.
    View in: PubMed Mentions: 29 Fields:
    Translation:HumansAnimals
  18. A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo. Proc Natl Acad Sci U S A. 2020 12 22; 117(51):32701-32710. Somayaji M, Cataldi S, Choi SJ, Edwards RH, Mosharov EV, Sulzer D. PMID: 33273122; PMCID: PMC7768743.
    View in: PubMed Mentions: 42 Fields:
    Translation:AnimalsCells
  19. Ion transport and regulation in a synaptic vesicle glutamate transporter. Science. 2020 05 22; 368(6493):893-897. Li F, Eriksen J, Finer-Moore J, Chang R, Nguyen P, Bowen A, Myasnikov A, Yu Z, Bulkley D, Cheng Y, Edwards RH, Stroud RM. PMID: 32439795; PMCID: PMC7388591.
    View in: PubMed Mentions: 35 Fields:
    Translation:AnimalsCells
  20. Perinatal interference with the serotonergic system affects VTA function in the adult via glutamate co-transmission. Mol Psychiatry. 2021 09; 26(9):4795-4812. Cunha C, Smiley JF, Chuhma N, Shah R, Bleiwas C, Menezes EC, Seal RP, Edwards RH, Rayport S, Ansorge MS, Castellanos FX, Teixeira CM. PMID: 32398719; PMCID: PMC7657958.
    View in: PubMed Mentions: 8 Fields:
    Translation:AnimalsCells
  21. The mechanism and regulation of vesicular glutamate transport: Coordination with the synaptic vesicle cycle. Biochim Biophys Acta Biomembr. 2020 12 01; 1862(12):183259. Eriksen J, Li F, Edwards RH. PMID: 32147354; PMCID: PMC7483692.
    View in: PubMed Mentions: 22 Fields:
    Translation:AnimalsCells
  22. The physiological role of α-synuclein and its relationship to Parkinson's Disease. J Neurochem. 2019 09; 150(5):475-486. Sulzer D, Edwards RH. PMID: 31269263; PMCID: PMC6707892.
    View in: PubMed Mentions: 178 Fields:
    Translation:HumansAnimalsCells
  23. Structures suggest a mechanism for energy coupling by a family of organic anion transporters. PLoS Biol. 2019 05; 17(5):e3000260. Leano JB, Batarni S, Eriksen J, Juge N, Pak JE, Kimura-Someya T, Robles-Colmenares Y, Moriyama Y, Stroud RM, Edwards RH. PMID: 31083648; PMCID: PMC6532931.
    View in: PubMed Mentions: 26 Fields:
    Translation:Cells
  24. Synaptic Vesicle Recycling Pathway Determines Neurotransmitter Content and Release Properties. Neuron. 2019 05 22; 102(4):786-800.e5. Silm K, Yang J, Marcott PF, Asensio CS, Eriksen J, Guthrie DA, Newman AH, Ford CP, Edwards RH. PMID: 31003725; PMCID: PMC6541489.
    View in: PubMed Mentions: 73 Fields:
    Translation:AnimalsCells
  25. Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments. Mol Psychiatry. 2020 04; 25(4):732-749. Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet JP, Bezzi P. PMID: 30127471; PMCID: PMC7156348.
    View in: PubMed Mentions: 59 Fields:
    Translation:AnimalsCells
  26. The dual role of chloride in synaptic vesicle glutamate transport. Elife. 2018 07 24; 7. Chang R, Eriksen J, Edwards RH. PMID: 30040066; PMCID: PMC6057745.
    View in: PubMed Mentions: 16 Fields:
    Translation:HumansAnimalsCells
  27. A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry. Nat Commun. 2018 01 23; 9(1):330. Ullman JC, Yang J, Sullivan M, Bendor J, Levy J, Pham E, Silm K, Seifikar H, Sohal VS, Nicoll RA, Edwards RH. PMID: 29362376; PMCID: PMC5780507.
    View in: PubMed Mentions: 16 Fields:
    Translation:HumansAnimalsCells
  28. Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons. eNeuro. 2017 Mar-Apr; 4(2). Pathak D, Berthet A, Bendor JT, Yu K, Sellnow RC, Orr AL, Nguyen MK, Edwards RH, Manfredsson FP, Nakamura K. PMID: 28462393; PMCID: PMC5409983.
    View in: PubMed Mentions: 11 Fields:
    Translation:AnimalsCells
  29. α-Synuclein promotes dilation of the exocytotic fusion pore. Nat Neurosci. 2017 May; 20(5):681-689. Logan T, Bendor J, Toupin C, Thorn K, Edwards RH. PMID: 28288128; PMCID: PMC5404982.
    View in: PubMed Mentions: 173 Fields:
    Translation:HumansAnimalsCells
  30. Endogenous Leucine-Rich Repeat Kinase 2 Slows Synaptic Vesicle Recycling in Striatal Neurons. Front Synaptic Neurosci. 2017; 9:5. Maas JW, Yang J, Edwards RH. PMID: 28280464; PMCID: PMC5322269.
    View in: PubMed Mentions: 13
  31. One Cycle Fuels Another: The Energetics of Neurotransmitter Release. Neuron. 2017 Feb 08; 93(3):470-472. Silm K, Edwards RH. PMID: 28182901.
    View in: PubMed Mentions: 2 Fields:
    Translation:Cells
  32. A slow excitatory postsynaptic current mediated by a novel metabotropic glutamate receptor in CA1 pyramidal neurons. Neuropharmacology. 2017 03 15; 115:4-9. Sheng N, Yang J, Silm K, Edwards RH, Nicoll RA. PMID: 27567940.
    View in: PubMed Mentions: 3 Fields:
    Translation:Animals
  33. Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron. 2016 06 15; 90(6):1189-1202. Mende M, Fletcher EV, Belluardo JL, Pierce JP, Bommareddy PK, Weinrich JA, Kabir ZD, Schierberl KC, Pagiazitis JG, Mendelsohn AI, Francesconi A, Edwards RH, Milner TA, Rajadhyaksha AM, van Roessel PJ, Mentis GZ, Kaltschmidt JA. PMID: 27263971; PMCID: PMC4912012.
    View in: PubMed Mentions: 25 Fields:
    Translation:AnimalsCells
  34. Protons Regulate Vesicular Glutamate Transporters through an Allosteric Mechanism. Neuron. 2016 05 18; 90(4):768-80. Eriksen J, Chang R, McGregor M, Silm K, Suzuki T, Edwards RH. PMID: 27133463; PMCID: PMC4886649.
    View in: PubMed Mentions: 40 Fields:
    Translation:AnimalsCells
  35. Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease. J Neurosci. 2015 Nov 11; 35(45):14983-99. Divito CB, Steece-Collier K, Case DT, Williams SP, Stancati JA, Zhi L, Rubio ME, Sortwell CE, Collier TJ, Sulzer D, Edwards RH, Zhang H, Seal RP. PMID: 26558771; PMCID: PMC4642234.
    View in: PubMed Mentions: 31 Fields:
    Translation:Animals
  36. Sex-dependent changes in metabolism and behavior, as well as reduced anxiety after eliminating ventromedial hypothalamus excitatory output. Mol Metab. 2015 Nov; 4(11):857-66. Cheung CC, Krause WC, Edwards RH, Yang CF, Shah NM, Hnasko TS, Ingraham HA. PMID: 26629409; PMCID: PMC4632173.
    View in: PubMed Mentions: 31 Fields:
  37. Is Aspartate an Excitatory Neurotransmitter? J Neurosci. 2015 Jul 15; 35(28):10168-71. Herring BE, Silm K, Edwards RH, Nicoll RA. PMID: 26180193; PMCID: PMC4502257.
    View in: PubMed Mentions: 36 Fields:
    Translation:AnimalsCells
  38. The role of mitochondrially derived ATP in synaptic vesicle recycling. J Biol Chem. 2015 Sep 11; 290(37):22325-36. Pathak D, Shields LY, Mendelsohn BA, Haddad D, Lin W, Gerencser AA, Kim H, Brand MD, Edwards RH, Nakamura K. PMID: 26126824; PMCID: PMC4566209.
    View in: PubMed Mentions: 161 Fields:
    Translation:AnimalsCells
  39. Mobile binding sites regulate glutamate clearance. Nat Neurosci. 2015 Feb; 18(2):166-8. Edwards RH. PMID: 25622571.
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    Translation:AnimalsCells
  40. A non-canonical pathway from cochlea to brain signals tissue-damaging noise. Curr Biol. 2015 Mar 02; 25(5):606-12. Flores EN, Duggan A, Madathany T, Hogan AK, Márquez FG, Kumar G, Seal RP, Edwards RH, Liberman MC, García-Añoveros J. PMID: 25639244; PMCID: PMC4348215.
    View in: PubMed Mentions: 83 Fields:
    Translation:AnimalsCellsPHPublic Health
  41. Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. J Neurosci. 2014 Oct 22; 34(43):14304-17. Berthet A, Margolis EB, Zhang J, Hsieh I, Zhang J, Hnasko TS, Ahmad J, Edwards RH, Sesaki H, Huang EJ, Nakamura K. PMID: 25339743; PMCID: PMC4205554.
    View in: PubMed Mentions: 120 Fields:
    Translation:AnimalsCells
  42. Efficient, complete deletion of synaptic proteins using CRISPR. Neuron. 2014 Sep 03; 83(5):1051-7. Incontro S, Asensio CS, Edwards RH, Nicoll RA. PMID: 25155957; PMCID: PMC4195490.
    View in: PubMed Mentions: 67 Fields:
    Translation:HumansAnimalsCells
  43. A population of glomerular glutamatergic neurons controls sensory information transfer in the mouse olfactory bulb. Nat Commun. 2014 May 07; 5:3791. Tatti R, Bhaukaurally K, Gschwend O, Seal RP, Edwards RH, Rodriguez I, Carleton A. PMID: 24804702; PMCID: PMC4028618.
    View in: PubMed Mentions: 29 Fields:
    Translation:AnimalsCells
  44. Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. Dev Cell. 2013 Nov 25; 27(4):425-37. Asensio CS, Sirkis DW, Maas JW, Egami K, To TL, Brodsky FM, Shu X, Cheng Y, Edwards RH. PMID: 24210660; PMCID: PMC3974617.
    View in: PubMed Mentions: 46 Fields:
    Translation:HumansAnimalsCells
  45. Widespread dysregulation of peptide hormone release in mice lacking adaptor protein AP-3. PLoS Genet. 2013; 9(9):e1003812. Sirkis DW, Edwards RH, Asensio CS. PMID: 24086151; PMCID: PMC3784564.
    View in: PubMed Mentions: 20 Fields:
    Translation:AnimalsCells
  46. The function of α-synuclein. Neuron. 2013 Sep 18; 79(6):1044-66. Bendor JT, Logan TP, Edwards RH. PMID: 24050397; PMCID: PMC3866954.
    View in: PubMed Mentions: 423 Fields:
    Translation:HumansAnimals
  47. Multiple dileucine-like motifs direct VGLUT1 trafficking. J Neurosci. 2013 Jun 26; 33(26):10647-60. Foss SM, Li H, Santos MS, Edwards RH, Voglmaier SM. PMID: 23804088; PMCID: PMC3693054.
    View in: PubMed Mentions: 36 Fields:
    Translation:AnimalsCells
  48. Ventral tegmental area glutamate neurons: electrophysiological properties and projections. J Neurosci. 2012 Oct 24; 32(43):15076-85. Hnasko TS, Hjelmstad GO, Fields HL, Edwards RH. PMID: 23100428; PMCID: PMC3685320.
    View in: PubMed Mentions: 152 Fields:
    Translation:AnimalsCells
  49. Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy. Neuron. 2012 Jul 26; 75(2):283-93. Akil O, Seal RP, Burke K, Wang C, Alemi A, During M, Edwards RH, Lustig LR. PMID: 22841313; PMCID: PMC3408581.
    View in: PubMed Mentions: 227 Fields:
    Translation:AnimalsCells
  50. AMP-activated kinase links serotonergic signaling to glutamate release for regulation of feeding behavior in C. elegans. Cell Metab. 2012 Jul 03; 16(1):113-21. Cunningham KA, Hua Z, Srinivasan S, Liu J, Lee BH, Edwards RH, Ashrafi K. PMID: 22768843; PMCID: PMC3413480.
    View in: PubMed Mentions: 46 Fields:
    Translation:AnimalsCells
  51. Fabs enable single particle cryoEM studies of small proteins. Structure. 2012 Apr 04; 20(4):582-92. Wu S, Avila-Sakar A, Kim J, Booth DS, Greenberg CH, Rossi A, Liao M, Li X, Alian A, Griner SL, Juge N, Yu Y, Mergel CM, Chaparro-Riggers J, Strop P, Tampé R, Edwards RH, Stroud RM, Craik CS, Cheng Y. PMID: 22483106; PMCID: PMC3322386.
    View in: PubMed Mentions: 101 Fields:
    Translation:HumansCells
  52. Vesicular and plasma membrane transporters for neurotransmitters. Cold Spring Harb Perspect Biol. 2012 Feb 01; 4(2). Blakely RD, Edwards RH. PMID: 22199021; PMCID: PMC3281572.
    View in: PubMed Mentions: 81 Fields:
    Translation:HumansAnimalsCells
  53. Dopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesia. J Clin Invest. 2012 Feb; 122(2):507-18. Lee HY, Nakayama J, Xu Y, Fan X, Karouani M, Shen Y, Pothos EN, Hess EJ, Fu YH, Edwards RH, Ptácek LJ. PMID: 22214848; PMCID: PMC3533379.
    View in: PubMed Mentions: 24 Fields:
    Translation:HumansAnimalsCells
  54. Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum. J Comp Neurol. 2011 Nov 01; 519(16):3346-66. Brumovsky PR, Robinson DR, La JH, Seroogy KB, Lundgren KH, Albers KM, Kiyatkin ME, Seal RP, Edwards RH, Watanabe M, Hökfelt T, Gebhart GF. PMID: 21800314; PMCID: PMC3919020.
    View in: PubMed Mentions: 21 Fields:
    Translation:AnimalsCells
  55. Neurotransmitter corelease: mechanism and physiological role. Annu Rev Physiol. 2012; 74:225-43. Hnasko TS, Edwards RH. PMID: 22054239; PMCID: PMC4090038.
    View in: PubMed Mentions: 161 Fields:
    Translation:HumansAnimalsCells
  56. Presynaptic regulation of quantal size: K+/H+ exchange stimulates vesicular glutamate transport. Nat Neurosci. 2011 Aug 28; 14(10):1285-92. Goh GY, Huang H, Ullman J, Borre L, Hnasko TS, Trussell LO, Edwards RH. PMID: 21874016; PMCID: PMC3183113.
    View in: PubMed Mentions: 45 Fields:
    Translation:AnimalsCells
  57. v-SNARE composition distinguishes synaptic vesicle pools. Neuron. 2011 Aug 11; 71(3):474-87. Hua Z, Leal-Ortiz S, Foss SM, Waites CL, Garner CC, Voglmaier SM, Edwards RH. PMID: 21835344; PMCID: PMC3155686.
    View in: PubMed Mentions: 110 Fields:
    Translation:AnimalsCells
  58. Pathway-specific genetic attenuation of glutamate release alters select features of competition-based visual circuit refinement. Neuron. 2011 Jul 28; 71(2):235-42. Koch SM, Dela Cruz CG, Hnasko TS, Edwards RH, Huberman AD, Ullian EM. PMID: 21791283; PMCID: PMC3375067.
    View in: PubMed Mentions: 35 Fields:
    Translation:AnimalsCells
  59. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem. 2011 Jun 10; 286(23):20710-26. Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. PMID: 21489994; PMCID: PMC3121472.
    View in: PubMed Mentions: 331 Fields:
    Translation:HumansAnimalsCells
  60. RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway. J Cell Biol. 2010 Dec 13; 191(6):1173-87. Asensio CS, Sirkis DW, Edwards RH. PMID: 21149569; PMCID: PMC3002028.
    View in: PubMed Mentions: 41 Fields:
    Translation:Animals
  61. Metabolic control of vesicular glutamate transport and release. Neuron. 2010 Oct 06; 68(1):99-112. Juge N, Gray JA, Omote H, Miyaji T, Inoue T, Hara C, Uneyama H, Edwards RH, Nicoll RA, Moriyama Y. PMID: 20920794; PMCID: PMC2978156.
    View in: PubMed Mentions: 204 Fields:
    Translation:HumansAnimalsCells
  62. Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate. J Neurosci. 2010 Jun 16; 30(24):8229-33. Stuber GD, Hnasko TS, Britt JP, Edwards RH, Bonci A. PMID: 20554874; PMCID: PMC2918390.
    View in: PubMed Mentions: 322 Fields:
    Translation:AnimalsCells
  63. Vesicular monoamine and glutamate transporters select distinct synaptic vesicle recycling pathways. J Neurosci. 2010 Jun 09; 30(23):7917-27. Onoa B, Li H, Gagnon-Bartsch JA, Elias LA, Edwards RH. PMID: 20534840; PMCID: PMC3184447.
    View in: PubMed Mentions: 37 Fields:
    Translation:AnimalsCells
  64. Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron. 2010 Mar 11; 65(5):643-56. Hnasko TS, Chuhma N, Zhang H, Goh GY, Sulzer D, Palmiter RD, Rayport S, Edwards RH. PMID: 20223200; PMCID: PMC2846457.
    View in: PubMed Mentions: 257 Fields:
    Translation:HumansAnimalsCells
  65. Glutamate co-release at GABA/glycinergic synapses is crucial for the refinement of an inhibitory map. Nat Neurosci. 2010 Feb; 13(2):232-8. Noh J, Seal RP, Garver JA, Edwards RH, Kandler K. PMID: 20081852; PMCID: PMC2832847.
    View in: PubMed Mentions: 106 Fields:
    Translation:AnimalsCells
  66. Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron. 2010 Jan 14; 65(1):66-79. Nemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll RA, Edwards RH. PMID: 20152114; PMCID: PMC3119527.
    View in: PubMed Mentions: 591 Fields:
    Translation:HumansAnimalsCells
  67. Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors. Nature. 2009 Dec 03; 462(7273):651-5. Seal RP, Wang X, Guan Y, Raja SN, Woodbury CJ, Basbaum AI, Edwards RH. PMID: 19915548; PMCID: PMC2810205.
    View in: PubMed Mentions: 230 Fields:
    Translation:AnimalsCells
  68. Dopamine release at individual presynaptic terminals visualized with FFNs. J Vis Exp. 2009 Aug 31; (30). Zhang H, Gubernator NG, Yue M, Staal RG, Mosharov EV, Pereira D, Balsanek V, Vadola PA, Mukherjee B, Edwards RH, Sulzer D, Sames D. PMID: 19721412; PMCID: PMC3253714.
    View in: PubMed Mentions: 5 Fields:
    Translation:AnimalsCells
  69. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science. 2009 Jun 12; 324(5933):1441-4. Gubernator NG, Zhang H, Staal RG, Mosharov EV, Pereira DB, Yue M, Balsanek V, Vadola PA, Mukherjee B, Edwards RH, Sulzer D, Sames D. PMID: 19423778; PMCID: PMC6696931.
    View in: PubMed Mentions: 104 Fields:
    Translation:AnimalsCells
  70. Synaptic and extrasynaptic factors governing glutamatergic retinal waves. Neuron. 2009 Apr 30; 62(2):230-41. Blankenship AG, Ford KJ, Johnson J, Seal RP, Edwards RH, Copenhagen DR, Feller MB. PMID: 19409268; PMCID: PMC2807181.
    View in: PubMed Mentions: 72 Fields:
    Translation:AnimalsCells
  71. Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. Neuron. 2009 Apr 30; 62(2):218-29. Mosharov EV, Larsen KE, Kanter E, Phillips KA, Wilson K, Schmitz Y, Krantz DE, Kobayashi K, Edwards RH, Sulzer D. PMID: 19409267; PMCID: PMC2677560.
    View in: PubMed Mentions: 271 Fields:
    Translation:HumansAnimalsCells
  72. What the neuron tells glia. Neuron. 2009 Mar 26; 61(6):811-2. Edwards R. PMID: 19323989.
    View in: PubMed Mentions: 1 Fields:
    Translation:AnimalsCells
  73. Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria. J Neurosci. 2008 Nov 19; 28(47):12305-17. Nakamura K, Nemani VM, Wallender EK, Kaehlcke K, Ott M, Edwards RH. PMID: 19020024; PMCID: PMC6671709.
    View in: PubMed Mentions: 114 Fields:
    Translation:AnimalsCells
  74. Fast subplasma membrane Ca2+ transients control exo-endocytosis of synaptic-like microvesicles in astrocytes. J Neurosci. 2008 Sep 10; 28(37):9122-32. Marchaland J, Calì C, Voglmaier SM, Li H, Regazzi R, Edwards RH, Bezzi P. PMID: 18784293; PMCID: PMC2846455.
    View in: PubMed Mentions: 56 Fields:
    Translation:AnimalsCells
  75. Vesicular glutamate and GABA transporters sort to distinct sets of vesicles in a population of presynaptic terminals. Cereb Cortex. 2009 Jan; 19(1):241-8. Boulland JL, Jenstad M, Boekel AJ, Wouterlood FG, Edwards RH, Storm-Mathisen J, Chaudhry FA. PMID: 18502731; PMCID: PMC3202896.
    View in: PubMed Mentions: 52 Fields:
    Translation:AnimalsCells
  76. Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3. Neuron. 2008 Jan 24; 57(2):263-75. Seal RP, Akil O, Yi E, Weber CM, Grant L, Yoo J, Clause A, Kandler K, Noebels JL, Glowatzki E, Lustig LR, Edwards RH. PMID: 18215623; PMCID: PMC2293283.
    View in: PubMed Mentions: 209 Fields:
    Translation:AnimalsCells
  77. Pharmacology of neurotransmitter transport into secretory vesicles. Handb Exp Pharmacol. 2008; (184):77-106. Chaudhry FA, Boulland JL, Jenstad M, Bredahl MK, Edwards RH. PMID: 18064412.
    View in: PubMed Mentions: 34 Fields:
    Translation:HumansAnimalsCells
  78. Vesicular neurotransmitter transporters as targets for endogenous and exogenous toxic substances. Annu Rev Pharmacol Toxicol. 2008; 48:277-301. Chaudhry FA, Edwards RH, Fonnum F. PMID: 17883368.
    View in: PubMed Mentions: 42 Fields:
    Translation:HumansAnimalsCells
  79. The neurotransmitter cycle and quantal size. Neuron. 2007 Sep 20; 55(6):835-58. Edwards RH. PMID: 17880890.
    View in: PubMed Mentions: 172 Fields:
    Translation:HumansAnimalsCells
  80. Physiology versus pathology in Parkinson's disease. Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):11867-8. Nakamura K, Edwards RH. PMID: 17623781; PMCID: PMC1924576.
    View in: PubMed Mentions: 2 Fields:
    Translation:AnimalsCells
  81. Vesicular glutamate transporter 1 is required for photoreceptor synaptic signaling but not for intrinsic visual functions. J Neurosci. 2007 Jul 04; 27(27):7245-55. Johnson J, Fremeau RT, Duncan JL, Rentería RC, Yang H, Hua Z, Liu X, LaVail MM, Edwards RH, Copenhagen DR. PMID: 17611277; PMCID: PMC2443709.
    View in: PubMed Mentions: 31 Fields:
    Translation:AnimalsCells
  82. Thyronamines inhibit plasma membrane and vesicular monoamine transport. ACS Chem Biol. 2007 Jun 15; 2(6):390-8. Snead AN, Santos MS, Seal RP, Miyakawa M, Edwards RH, Scanlan TS. PMID: 17530732.
    View in: PubMed Mentions: 26 Fields:
    Translation:HumansAnimalsCells
  83. Do different endocytic pathways make different synaptic vesicles? Curr Opin Neurobiol. 2007 Jun; 17(3):374-80. Voglmaier SM, Edwards RH. PMID: 17449236.
    View in: PubMed Mentions: 33 Fields:
    Translation:AnimalsCells
  84. Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis. J Neurosci. 2006 Nov 15; 26(46):11915-22. Larsen KE, Schmitz Y, Troyer MD, Mosharov E, Dietrich P, Quazi AZ, Savalle M, Nemani V, Chaudhry FA, Edwards RH, Stefanis L, Sulzer D. PMID: 17108165; PMCID: PMC6674868.
    View in: PubMed Mentions: 232 Fields:
    Translation:AnimalsCells
  85. Secretion of L-glutamate from osteoclasts through transcytosis. EMBO J. 2006 Sep 20; 25(18):4175-86. Morimoto R, Uehara S, Yatsushiro S, Juge N, Hua Z, Senoh S, Echigo N, Hayashi M, Mizoguchi T, Ninomiya T, Udagawa N, Omote H, Yamamoto A, Edwards RH, Moriyama Y. PMID: 16957773; PMCID: PMC1570443.
    View in: PubMed Mentions: 42 Fields:
    Translation:AnimalsCells
  86. Synaptic vesicles: half full or half empty? Neuron. 2006 Sep 07; 51(5):523-4. Hnasko TS, Edwards RH. PMID: 16950150.
    View in: PubMed Mentions: Fields:
    Translation:HumansAnimalsCells
  87. Alpha-synuclein overexpression increases cytosolic catecholamine concentration. J Neurosci. 2006 Sep 06; 26(36):9304-11. Mosharov EV, Staal RG, Bové J, Prou D, Hananiya A, Markov D, Poulsen N, Larsen KE, Moore CM, Troyer MD, Edwards RH, Przedborski S, Sulzer D. PMID: 16957086; PMCID: PMC6674515.
    View in: PubMed Mentions: 69 Fields:
    Translation:AnimalsCells
  88. Distribution of vesicular glutamate transporters 1 and 2 in the rat spinal cord, with a note on the spinocervical tract. J Comp Neurol. 2006 Aug 10; 497(5):683-701. Persson S, Boulland JL, Aspling M, Larsson M, Fremeau RT, Edwards RH, Storm-Mathisen J, Chaudhry FA, Broman J. PMID: 16786558.
    View in: PubMed Mentions: 39 Fields:
    Translation:AnimalsCells
  89. Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling. Neuron. 2006 Jul 06; 51(1):71-84. Voglmaier SM, Kam K, Yang H, Fortin DL, Hua Z, Nicoll RA, Edwards RH. PMID: 16815333.
    View in: PubMed Mentions: 239 Fields:
    Translation:AnimalsCells
  90. PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB network. Pharmacol Rev. 2006 Mar; 58(1):5-6. Badagnani I, Sorani M, Edwards RH, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson EJ, Taylor T, Chan W, De La Cruz M, Ferrin TE, Burchard EG, Herskowitz I, Kroetz DL, Giacomini KM. PMID: 16507879.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans
  91. Changes in purinergic signaling after cerebral injury -- involvement of glutamatergic mechanisms? Int J Dev Neurosci. 2006 Apr-May; 24(2-3):123-32. Franke H, Grummich B, Härtig W, Grosche J, Regenthal R, Edwards RH, Illes P, Krügel U. PMID: 16387466.
    View in: PubMed Mentions: 22 Fields:
    Translation:AnimalsCells
  92. Functional implications of neurotransmitter co-release: glutamate and GABA share the load. Curr Opin Pharmacol. 2006 Feb; 6(1):114-9. Seal RP, Edwards RH. PMID: 16359920.
    View in: PubMed Mentions: 37 Fields:
    Translation:HumansAnimalsCells
  93. Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines. Neuron. 2005 Nov 23; 48(4):619-33. Li H, Waites CL, Staal RG, Dobryy Y, Park J, Sulzer DL, Edwards RH. PMID: 16301178.
    View in: PubMed Mentions: 47 Fields:
    Translation:AnimalsCells
  94. Neural activity controls the synaptic accumulation of alpha-synuclein. J Neurosci. 2005 Nov 23; 25(47):10913-21. Fortin DL, Nemani VM, Voglmaier SM, Anthony MD, Ryan TA, Edwards RH. PMID: 16306404; PMCID: PMC6725870.
    View in: PubMed Mentions: 152 Fields:
    Translation:AnimalsCells
  95. A combinatorial code for the interaction of alpha-synuclein with membranes. J Biol Chem. 2005 Sep 09; 280(36):31664-72. Kubo S, Nemani VM, Chalkley RJ, Anthony MD, Hattori N, Mizuno Y, Edwards RH, Fortin DL. PMID: 16020543.
    View in: PubMed Mentions: 99 Fields:
    Translation:HumansAnimalsCells
  96. Antidepressants and the monoamine masquerade. Neuron. 2005 Apr 07; 46(1):1-2. Sulzer D, Edwards RH. PMID: 15820686.
    View in: PubMed Mentions: 12 Fields:
    Translation:HumansAnimalsCells
  97. Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters. J Comp Neurol. 2004 Dec 13; 480(3):264-80. Boulland JL, Qureshi T, Seal RP, Rafiki A, Gundersen V, Bergersen LH, Fremeau RT, Edwards RH, Storm-Mathisen J, Chaudhry FA. PMID: 15515175.
    View in: PubMed Mentions: 126 Fields:
    Translation:AnimalsCells
  98. Normal biogenesis and cycling of empty synaptic vesicles in dopamine neurons of vesicular monoamine transporter 2 knockout mice. Mol Biol Cell. 2005 Jan; 16(1):306-15. Croft BG, Fortin GD, Corera AT, Edwards RH, Beaudet A, Trudeau LE, Fon EA. PMID: 15496457; PMCID: PMC539174.
    View in: PubMed Mentions: 10 Fields:
    Translation:AnimalsCells
  99. Evidence that certain retinal bipolar cells use both glutamate and GABA. J Comp Neurol. 2004 Oct 18; 478(3):207-18. Kao YH, Lassová L, Bar-Yehuda T, Edwards RH, Sterling P, Vardi N. PMID: 15368537.
    View in: PubMed Mentions: 23 Fields:
    Translation:AnimalsCells
  100. Vesicular glutamate transporter 3 expression identifies glutamatergic amacrine cells in the rodent retina. J Comp Neurol. 2004 Sep 27; 477(4):386-98. Johnson J, Sherry DM, Liu X, Fremeau RT, Seal RP, Edwards RH, Copenhagen DR. PMID: 15329888; PMCID: PMC2586940.
    View in: PubMed Mentions: 63 Fields:
    Translation:AnimalsCells
  101. The effect of rare human sequence variants on the function of vesicular monoamine transporter 2. Pharmacogenetics. 2004 Sep; 14(9):587-94. Burman J, Tran CH, Glatt C, Freimer NB, Edwards RH. PMID: 15475732.
    View in: PubMed Mentions: 8 Fields:
    Translation:HumansAnimalsCells
  102. Lipid rafts mediate the synaptic localization of alpha-synuclein. J Neurosci. 2004 Jul 28; 24(30):6715-23. Fortin DL, Troyer MD, Nakamura K, Kubo S, Anthony MD, Edwards RH. PMID: 15282274; PMCID: PMC6729723.
    View in: PubMed Mentions: 255 Fields:
    Translation:HumansAnimalsCells
  103. Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3. J Neurosci. 2004 May 26; 24(21):4978-88. Harkany T, Holmgren C, Härtig W, Qureshi T, Chaudhry FA, Storm-Mathisen J, Dobszay MB, Berghuis P, Schulte G, Sousa KM, Fremeau RT, Edwards RH, Mackie K, Ernfors P, Zilberter Y. PMID: 15163690; PMCID: PMC6729377.
    View in: PubMed Mentions: 38 Fields:
    Translation:AnimalsCells
  104. Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites. Science. 2004 Jun 18; 304(5678):1815-9. Fremeau RT, Kam K, Qureshi T, Johnson J, Copenhagen DR, Storm-Mathisen J, Chaudhry FA, Nicoll RA, Edwards RH. PMID: 15118123.
    View in: PubMed Mentions: 231 Fields:
    Translation:AnimalsCells
  105. VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate. Trends Neurosci. 2004 Feb; 27(2):98-103. Fremeau RT, Voglmaier S, Seal RP, Edwards RH. PMID: 15102489.
    View in: PubMed Mentions: 353 Fields:
    Translation:HumansAnimalsCells
  106. Cellular localization of three vesicular glutamate transporter mRNAs and proteins in rat spinal cord and dorsal root ganglia. Synapse. 2003 Nov; 50(2):117-29. Oliveira AL, Hydling F, Olsson E, Shi T, Edwards RH, Fujiyama F, Kaneko T, Hökfelt T, Cullheim S, Meister B. PMID: 12923814.
    View in: PubMed Mentions: 108 Fields:
    Translation:AnimalsCells
  107. Complementary distribution of vesicular glutamate transporters 1 and 2 in the nucleus accumbens of rat: Relationship to calretinin-containing extrinsic innervation and calbindin-immunoreactive neurons. J Comp Neurol. 2003 Oct 06; 465(1):1-10. Härtig W, Riedel A, Grosche J, Edwards RH, Fremeau RT, Harkany T, Brauer K, Arendt T. PMID: 12926012.
    View in: PubMed Mentions: 20 Fields:
    Translation:AnimalsCells
  108. Plasma membrane and vesicular glutamate transporter mRNAs/proteins in hypothalamic neurons that regulate body weight. Eur J Neurosci. 2003 Sep; 18(5):1265-78. Collin M, Bäckberg M, Ovesjö ML, Fisone G, Edwards RH, Fujiyama F, Meister B. PMID: 12956725.
    View in: PubMed Mentions: 51 Fields:
    Translation:AnimalsCells
  109. Organic anion transport is the primary function of the SLC17/type I phosphate transporter family. Pflugers Arch. 2004 Feb; 447(5):629-35. Reimer RJ, Edwards RH. PMID: 12811560.
    View in: PubMed Mentions: 71 Fields:
    Translation:HumansAnimals
  110. The H+-coupled electrogenic lysosomal amino acid transporter LYAAT1 localizes to the axon and plasma membrane of hippocampal neurons. J Neurosci. 2003 Feb 15; 23(4):1265-75. Wreden CC, Johnson J, Tran C, Seal RP, Copenhagen DR, Reimer RJ, Edwards RH. PMID: 12598615; PMCID: PMC6742289.
    View in: PubMed Mentions: 22 Fields:
    Translation:HumansAnimalsCells
  111. Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamate. J Neurosci. 2003 Jan 15; 23(2):518-29. Johnson J, Tian N, Caywood MS, Reimer RJ, Edwards RH, Copenhagen DR. PMID: 12533612; PMCID: PMC6741860.
    View in: PubMed Mentions: 106 Fields:
    Translation:AnimalsCells
  112. Expression of plasma membrane GABA transporters but not of the vesicular GABA transporter in dentate granule cells after kainic acid seizures. Hippocampus. 2003; 13(7):806-15. Sperk G, Schwarzer C, Heilman J, Furtinger S, Reimer RJ, Edwards RH, Nelson N. PMID: 14620876.
    View in: PubMed Mentions: 30 Fields:
    Translation:AnimalsCells
  113. The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate. Proc Natl Acad Sci U S A. 2002 Oct 29; 99(22):14488-93. Fremeau RT, Burman J, Qureshi T, Tran CH, Proctor J, Johnson J, Zhang H, Sulzer D, Copenhagen DR, Storm-Mathisen J, Reimer RJ, Chaudhry FA, Edwards RH. PMID: 12388773; PMCID: PMC137910.
    View in: PubMed Mentions: 213 Fields:
    Translation:HumansAnimalsCells
  114. Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. J Neurosci. 2002 Oct 15; 22(20):8951-60. Larsen KE, Fon EA, Hastings TG, Edwards RH, Sulzer D. PMID: 12388602; PMCID: PMC6757693.
    View in: PubMed Mentions: 150 Fields:
    Translation:AnimalsCells
  115. Cell-specific expression of the glutamine transporter SN1 suggests differences in dependence on the glutamine cycle. Eur J Neurosci. 2002 May; 15(10):1615-31. Boulland JL, Osen KK, Levy LM, Danbolt NC, Edwards RH, Storm-Mathisen J, Chaudhry FA. PMID: 12059969.
    View in: PubMed Mentions: 55 Fields:
    Translation:AnimalsCells
  116. The glutamine commute: take the N line and transfer to the A. J Cell Biol. 2002 Apr 29; 157(3):349-55. Chaudhry FA, Reimer RJ, Edwards RH. PMID: 11980913; PMCID: PMC2173294.
    View in: PubMed Mentions: 92 Fields:
    Translation:Cells
  117. Regulation of the glutamine transporter SN1 by extracellular pH and intracellular sodium ions. J Physiol. 2002 Feb 15; 539(Pt 1):3-14. Bröer A, Albers A, Setiawan I, Edwards RH, Chaudhry FA, Lang F, Wagner CA, Bröer S. PMID: 11850497; PMCID: PMC2290136.
    View in: PubMed Mentions: 38 Fields:
    Translation:AnimalsCells
  118. Glutamine uptake by neurons: interaction of protons with system a transporters. J Neurosci. 2002 Jan 01; 22(1):62-72. Chaudhry FA, Schmitz D, Reimer RJ, Larsson P, Gray AT, Nicoll R, Kavanaugh M, Edwards RH. PMID: 11756489; PMCID: PMC6757603.
    View in: PubMed Mentions: 90 Fields:
    Translation:HumansAnimalsCells

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