Zachary Steinhart • UCSF Profiles (original) (raw)
- Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells. bioRxiv. 2025 Dec 14. Jung H, Devant P, Ching C, Ota M, Hamilton J, Steinhart Z, Ngo W, Sandoval L, Jung JH, Xu D, An M, Urs E, Chen PA, Allain V, Tada T, Nuñez JK, Landau NR, Liu DR, Eyquem J, Doudna JA, Marson A, Carnevale J. PMID: 41415457; PMCID: PMC12710740.
View in: PubMed Mentions: - Novel regulators of heparan sulfate proteoglycans modulate cellular uptake of α-synuclein fibrils. Commun Biol. 2025 Oct 06; 8(1):1426. Vanderperre B, Muraleedharan A, Dorion MF, Larroquette F, Del Cid Pellitero E, Rajakulendran N, Chen CX, Larivière R, Michaud-Tardif C, Goiran T, Chidiac R, Lipuma D, MacLeod G, Thomas R, Wang Z, Reintsch WE, Luo W, Shlaifer I, Zhang F, Xia K, Steinhart Z, Linhardt RJ, Trempe JF, Liu J, Durcan TM, Angers S, Fon EA. PMID: 41053297; PMCID: PMC12501064.
View in: PubMed Mentions: 1 Translation:HumansAnimalsCells - Central control of dynamic gene circuits governs T cell rest and activation. Nature. 2025 01; 637(8047):930-939. Arce MM, Umhoefer JM, Arang N, Kasinathan S, Freimer JW, Steinhart Z, Shen H, Pham MTN, Ota M, Wadhera A, Dajani R, Dorovskyi D, Chen YY, Liu Q, Zhou Y, Swaney DL, Obernier K, Shy BR, Carnevale J, Satpathy AT, Krogan NJ, Pritchard JK, Marson A. PMID: 39663454; PMCID: PMC11754113.
View in: PubMed Mentions: 12 Fields:
Translation:HumansCells - Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells. Nat Genet. 2024 Jun; 56(6):1156-1167. Mowery CT, Freimer JW, Chen Z, Casaní-Galdón S, Umhoefer JM, Arce MM, Gjoni K, Daniel B, Sandor K, Gowen BG, Nguyen V, Simeonov DR, Garrido CM, Curie GL, Schmidt R, Steinhart Z, Satpathy AT, Pollard KS, Corn JE, Bernstein BE, Ye CJ, Marson A. PMID: 38811842; PMCID: PMC11176074.
View in: PubMed Mentions: 8 Fields:
Translation:HumansCells - Bidirectional epigenetic editing reveals hierarchies in gene regulation. Nat Biotechnol. 2025 Mar; 43(3):355-368. Pacalin NM, Steinhart Z, Shi Q, Belk JA, Dorovskyi D, Kraft K, Parker KR, Shy BR, Marson A, Chang HY. PMID: 38760566; PMCID: PMC11569274.
View in: PubMed Mentions: 14 Fields:
Translation:HumansCells - An evolved AAV variant enables efficient genetic engineering of murine T cells. Cell. 2023 01 19; 186(2):446-460.e19. Nyberg WA, Ark J, To A, Clouden S, Reeder G, Muldoon JJ, Chung JY, Xie WH, Allain V, Steinhart Z, Chang C, Talbot A, Kim S, Rosales A, Havlik LP, Pimentel H, Asokan A, Eyquem J. PMID: 36638795; PMCID: PMC10540678.
View in: PubMed Mentions: 50 Fields:
Translation:AnimalsCells - SCFFBXW7 regulates G2-M progression through control of CCNL1 ubiquitination. EMBO Rep. 2022 12 06; 23(12):e55044. O'Brien S, Kelso S, Steinhart Z, Orlicky S, Mis M, Kim Y, Lin S, Sicheri F, Angers S. PMID: 36278408; PMCID: PMC9724663.
View in: PubMed Mentions: 11 Fields:
Translation:HumansCells - CRISPR activation and interference screens decode stimulation responses in primary human T cells. Science. 2022 02 04; 375(6580):eabj4008. Schmidt R, Steinhart Z, Layeghi M, Freimer JW, Bueno R, Nguyen VQ, Blaeschke F, Ye CJ, Marson A. PMID: 35113687; PMCID: PMC9307090.
View in: PubMed Mentions: 164 Fields:
Translation:HumansCells - Evaluation of SARS-CoV-2 serology assays reveals a range of test performance. Nat Biotechnol. 2020 10; 38(10):1174-1183. Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk RP, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. PMID: 32855547; PMCID: PMC7740072.
View in: PubMed Mentions: 157 Fields:
Translation:HumansCellsPHPublic Health - Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer. Nat Commun. 2020 07 24; 11(1):3701. Aubert L, Nandagopal N, Steinhart Z, Lavoie G, Nourreddine S, Berman J, Saba-El-Leil MK, Papadopoli D, Lin S, Hart T, Macleod G, Topisirovic I, Gaboury L, Fahrni CJ, Schramek D, Meloche S, Angers S, Roux PP. PMID: 32709883; PMCID: PMC7381612.
View in: PubMed Mentions: 138 Fields:
Translation:HumansAnimalsCells - Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation. Proc Natl Acad Sci U S A. 2020 07 14; 117(28):16690-16701. Ma W, Chen M, Kang H, Steinhart Z, Angers S, He X, Kirschner MW. PMID: 32601235; PMCID: PMC7368285.
View in: PubMed Mentions: 38 Fields:
Translation:HumansCells - Test performance evaluation of SARS-CoV-2 serological assays. medRxiv. 2020 May 17. Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk R, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. PMID: 32511497; PMCID: PMC7273265.
View in: PubMed Mentions: 12 - IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers. J Cell Biol. 2020 02 03; 219(2). Mis M, O'Brien S, Steinhart Z, Lin S, Hart T, Moffat J, Angers S. PMID: 31881079; PMCID: PMC7041691.
View in: PubMed Mentions: 21 Fields:
Translation:HumansCells - Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice. Elife. 2019 08 27; 8. Tao Y, Mis M, Blazer L, Ustav M, Steinhart Z, Chidiac R, Kubarakos E, O'Brien S, Wang X, Jarvik N, Patel N, Adams J, Moffat J, Angers S, Sidhu SS. PMID: 31452509; PMCID: PMC6711705.
View in: PubMed Mentions: 49 Fields:
Translation:HumansAnimalsCells - Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells. Cell Rep. 2019 04 16; 27(3):971-986.e9. MacLeod G, Bozek DA, Rajakulendran N, Monteiro V, Ahmadi M, Steinhart Z, Kushida MM, Yu H, Coutinho FJ, Cavalli FMG, Restall I, Hao X, Hart T, Luchman HA, Weiss S, Dirks PB, Angers S. PMID: 30995489.
View in: PubMed Mentions: 139 Fields:
Translation:HumansAnimalsCells - A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties. MAbs. 2018 Nov-Dec; 10(8):1157-1167. Pavlovic Z, Adams JJ, Blazer LL, Gakhal AK, Jarvik N, Steinhart Z, Robitaille M, Mascall K, Pan J, Angers S, Moffat J, Sidhu SS. PMID: 30183492; PMCID: PMC6284576.
View in: PubMed Mentions: 33 Fields:
Translation:HumansCells - Wnt signaling in development and tissue homeostasis. Development. 2018 06 08; 145(11). Steinhart Z, Angers S. PMID: 29884654.
View in: PubMed Mentions: 447 Fields:
Translation:HumansAnimalsCells - Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nat Med. 2017 Nov 07; 23(11):1384. Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. PMID: 29117169.
View in: PubMed Mentions: 4 Fields: - Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nat Med. 2017 01; 23(1):60-68. Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. PMID: 27869803.
View in: PubMed Mentions: 164 Fields:
Translation:HumansAnimalsCells - Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay. J Cell Sci. 2016 10 15; 129(20):3892-3902. Gammons MV, Rutherford TJ, Steinhart Z, Angers S, Bienz M. PMID: 27744318; PMCID: PMC5087658.
View in: PubMed Mentions: 55 Fields:
Translation:HumansCells - Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):9304-9. Cervenka I, Valnohova J, Bernatik O, Harnos J, Radsetoulal M, Sedova K, Hanakova K, Potesil D, Sedlackova M, Salasova A, Steinhart Z, Angers S, Schulte G, Hampl A, Zdrahal Z, Bryja V. PMID: 27486244; PMCID: PMC4995965.
View in: PubMed Mentions: 38 Fields:
Translation:HumansCells - High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. Cell. 2015 Dec 03; 163(6):1515-26. Hart T, Chandrashekhar M, Aregger M, Steinhart Z, Brown KR, MacLeod G, Mis M, Zimmermann M, Fradet-Turcotte A, Sun S, Mero P, Dirks P, Sidhu S, Roth FP, Rissland OS, Durocher D, Angers S, Moffat J. PMID: 26627737.
View in: PubMed Mentions: 949 Fields:
Translation:HumansCells
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This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
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