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Papers by Giselle Baquero

JACC. Cardiovascular interventions, Jan 20, 2015

We thank Drs. Chugh and Chugh for their interest in our work (1) and for their comments. We agree... more We thank Drs. Chugh and Chugh for their interest in our work (1) and for their comments. We agree that access failure remains a limitation of transradial intervention (TRI). As demonstrated in SAFE-PCI for Women (Study of Access Site for Enhancement of PCI for Women) trial, radial artery spasm (RAS) is a major contributor to access site crossover from radial to femoral. Women generally

Isolated left ventricular noncompaction (ILVNC) is a rare form of cardiomyopathy characterized by... more Isolated left ventricular noncompaction (ILVNC) is a rare form of cardiomyopathy characterized by prominent left ventricular trabeculations and intertrabecular recesses. Most common clinical manifestations are severe systolic and diastolic dysfunction, conduction abnormalities and cardioembolic events. Evidence based recommendations for the prevention of thromboembolic events in ILVNC have not been established. We report the case of a young woman initially diagnosed with hypertrophic cardiomyopathy (HCM) without systolic dysfunction who presented with left hemiparesis due to a large right hemispheric ischemic stroke, later diagnosed with ILVNC. A 30-year-old female with a previous diagnosis of HCM and an implantable cardioverter defibrillator (ICD) for primary prevention presented with complaints of left sided weakness and slurred speech. The patient was diagnosed with an ischemic right caudate/lentiform infarct, compatible with a cardioembolic stroke. A Transthoracic echocardiogram...

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2014

Critical pathways in cardiology, 2014

We identified all patients with age 21 years and older, without a history of obstructive coronary... more We identified all patients with age 21 years and older, without a history of obstructive coronary artery disease, who presented to the emergency department with chest pain, and were admitted for cardiac observation followed by stress echocardiography during a 1-year period. The positive predictive value of stress echocardiography and cardiovascular outcomes were compared based on patients' Diamond chest pain classification. In patients with typical chest pain, who accounted for 8.7% (44/503) of the total cohort, the positive predictive value of stress echocardiography was 75% compared with 0% for all other subgroups (P = 0.007). Six patients (14%) with typical chest pain went on to have coronary revascularization compared with 0% for all other subgroups (P < 0.001). No patient in any subgroup died or was readmitted with a myocardial infarction in 30 days. Applying the Diamond criteria could improve utilization of stress echocardiography for patients with low-risk chest pain i...

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013

Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital, 2013

Isolated left ventricular noncompaction is a rare form of cardiomyopathy characterized by promine... more Isolated left ventricular noncompaction is a rare form of cardiomyopathy characterized by prominent left ventricular trabeculations and intertrabecular recesses. The typical clinical manifestations are severe systolic and diastolic dysfunction, conduction abnormalities, and cardiac embolic events theorized to result from thrombus formation within the intertrabecular recesses. Evidence-based recommendations for preventing thromboembolic events in isolated left ventricular noncompaction have not been established. We report the case of a woman who, at 10 years of age, had been diagnosed with hypertrophic cardiomyopathy without systolic dysfunction. At age 30, she presented with left hemiparesis consequent to a large right-hemispheric ischemic stroke, and she was diagnosed with isolated left ventricular noncompaction. In addition to discussing the patient's case, we review the medical literature that pertains to isolated left ventricular noncompaction.

Catheterization and Cardiovascular Interventions, 2014

ABSTRACT The meta‐analysis examines the efficacy of high dose preloading of statin prior to PCI a... more ABSTRACT The meta‐analysis examines the efficacy of high dose preloading of statin prior to PCI and demonstrate its association with lower PMI and cardiovascular events at short‐term.Results from this analysis should encourage high‐dose pretreatment with statins prior to PCI, especially in patients with NSTE‐ACS.A large randomize clinical trial would be desirable but not entirely necessary to initiate adoption of this novel strategy.

Archivos de cardiologia …, 2010

Cardiac resynchronization therapy (CRT) is an established treatment modality for systolic heart f... more Cardiac resynchronization therapy (CRT) is an established treatment modality for systolic heart failure. Aimed to produce simultaneous biventricular stimulation and correct the lack of ventricular synchrony in selected patients with congestive heart failure, CRT ...

Circulation. Cardiovascular interventions, 2014

Current Heart Failure Reports, 2014

Most cardiovascular implantable electronic devices (CIEDs) require a ventricular lead to be place... more Most cardiovascular implantable electronic devices (CIEDs) require a ventricular lead to be placed across the tricuspid valve. Tricuspid regurgitation (TR) is an understudied clinical complication of right ventricular lead implantation and its clinical significance is unknown. We review the incidence, predictors, and current management of TR as a complication of ventricular lead implantation. Emerging technologies, including leadless pacing devices and subcutaneous systems, offer the benefit of little or none tricuspid valve disruption.

Journal of Electrocardiology, 2015

Importance: AliveCor ECG is an FDA approved ambulatory cardiac rhythm monitor that records a sing... more Importance: AliveCor ECG is an FDA approved ambulatory cardiac rhythm monitor that records a single channel (lead I) ECG rhythm strip using an iPhone. In the past few years, the use of smartphones and tablets with health related applications has significantly proliferated. Objective: In this initial feasibility trial, we attempted to reproduce the 12 lead ECG using the bipolar arrangement of the AliveCor monitor coupled to smart phone technology. Methods: We used the AliveCor heart monitor coupled with an iPhone cellular phone and the AliveECG application (APP) in 5 individuals. Results: In our 5 individuals, recordings from both a standard 12 lead ECG and the AliveCor generated 12 lead ECG had the same interpretation.

Journal of the American Society of Hypertension, 2014

The Journal of ECT, 2010

Electroconvulsive therapy (ECT) is recommended by the American Psychiatric Association Task Force... more Electroconvulsive therapy (ECT) is recommended by the American Psychiatric Association Task Force on ECT as a safe and effective treatment of depression throughout pregnancy. We report here administration of ECT in the third trimester of pregnancy in a 33-year-old patient with severe bipolar depression.

Journal of the American College of Cardiology, 2013

diagnostic and or coronary intervention was attempted in 2665 patients via radial approach. Trans... more diagnostic and or coronary intervention was attempted in 2665 patients via radial approach. Transradial approach was unsuccessful in 162 patients (6.1%) necessitating crossover to either femoral approach in 119 patients (4.5%) or ulnar route in 43 patients (1.6%), the ulnar patients constituted our study population. Selective forearm angiography was performed immediately after the procedure. Procedural characteristics and major adverse cerebrovascular and cardiovascular events were documented. Results: Results: Radial artery spasm was the commonest cause of crossover to the ulnar approach (65%) followed by failure to puncture the radial artery (32%). Percutaneous coronary intervention was performed in 17 cases (39%), of which 8 (47%) were emergency interventions. Successful procedure was achieved in 38 patients (88%). The 5 failed cases (12%) were mainly due to absent ulnar pulse (80%) and ulnar artery spasm (20%). Complications observed include transient numbness in 7 patients (16.3%), non-significant hematoma in 6 patients (13.9%) and one ulnar artery perforation (2.3%) that treated conservatively. No major cardiac-cerebrovascular events or hand ischemia were noted. Conclusions: Conclusion Ulnar access for coronary procedures is a feasible alternative whenever radial route fails. It gives an opportunity of avoiding crossover to femoral approach. Our study confirms satisfactory success rate of ulnar approach in presence of adequate pulse intensity and relatively low rate of complications.

Journal of Interventional Cardiac Electrophysiology, 2013

Purpose Cardiac rhythm management devices (CRMD) require a ventricular lead to be placed across t... more Purpose Cardiac rhythm management devices (CRMD) require a ventricular lead to be placed across the tricuspid valve. Tricuspid regurgitation (TR) is an under-recognized clinical complication of lead implantation and its clinical significance is unknown. We studied the incidence of hospitalizations for congestive heart failure (CHF) exacerbation among patients with worsening TR after ventricular lead implantation. Methods We reviewed 148 patients (age 68±15) that received a CRMD. TR and pulmonary artery systolic pressure (PASP) measured by Doppler echocardiography before and after CRMD implantation were analyzed. Hospitalizations for CHF exacerbation post-implantation were counted. Results Follow-up was 32±14 months. Ninety-nine (67 %) patients had no change, 24 (16 %) slight, and 9 (6 %) significant increase in TR after CRMD implantation, while 13 (9 %) patients had slight and 3 (2 %) significant improvement. Patients with a significant increase in TR had higher incidence of hospitalizations (1.7±0.5) compared to patients with slight (0.8±1; p =0.006) or no increase (0.5±1; p =0.0002) in TR. Patients with significant increase in TR had a greater change in PASP (25 mmHg; p =0.002) after device implantation compared to those with a slight (10 mmHg; p =0.002) or no increase (0.7 mmHg; p =0.17). Conclusion Increased TR following CRMD implantation is relatively common (33 %) and correlated with subsequent risk of hospitalization for heart failure. A preventive strategy and close monitoring for development or worsening of CHF after CRMD implantation may help prevent hospital admissions.

Journal of Cardiovascular Electrophysiology, 2012

Dofetilide Reduces VT/VF and ICD Therapies. Background: Patients with an implanted cardioverter d... more Dofetilide Reduces VT/VF and ICD Therapies. Background: Patients with an implanted cardioverter defibrillator (ICD) and ventricular arrhythmias leading to ICD therapies have poor clinical outcomes and quality of life. Antiarrhythmic agents and catheter ablation are needed to control these arrhythmias. Dofetilide has only been approved for the treatment of atrial fibrillation. The role of dofetilide in the control of ventricular arrhythmias in patients with an ICD has not been established.