Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma - PubMed (original) (raw)
Case Reports
. 1999 Mar 10;52(4):864-7.
doi: 10.1212/wnl.52.4.864.
Affiliations
- PMID: 10078744
- DOI: 10.1212/wnl.52.4.864
Case Reports
Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma
J L Bennett et al. Neurology. 1999.
Abstract
The authors report two patients with testicular cancer who exhibited supranuclear gaze disorders as a manifestation of a paraneoplastic brainstem encephalomyelitis. In the first patient, neuro-ophthalmic dysfunction was accompanied by a prominent limbic encephalitis whereas in the second patient, an unusual, mixed pendular and jerk nystagmus was manifested. Neuroimaging revealed an enhancing hypothalamic mass in the first patient and was negative in the second. Blood from both patients contained an antibody previously reported in a patient with limbic encephalitis and testicular cancer.
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