Molecular characteristics of fibroblast growth factor-fibroblast growth factor receptor-heparin-like glycosaminoglycan complex - PubMed (original) (raw)

Multiple sequence alignment of FGF-1 to FGF-18 by the

clustalw

program (22). Boxes mark regions of highly conserved amino acid residues as described in Methods. FGF-1 to FGF-9 and FHF-11 to FGF-14 were obtained from the SwissProt database. FGF-10 and FGF-15 to FGF-18 were obtained from the GenBank database. The accession numbers for the FGFs are as follows: FGF-1 (acidic FGF, aFGF), P05230; FGF-2 (basic FGF, bFGF), P09038; FGF-3 (INT-2, protooncogene protein precursor), P11487; FGF-4 (KS3 or heparin secretory transforming protein 1, HST-1), P08620; FGF-5, P12034; FGF-6 (heparin secretory transforming protein 2, HST-2), P10767; FGF-7 (keratinocyte growth factor, KGF), P21781; FGF-8 (androgen-induced growth factor, AIGF), P55075; FGF-9 (glia-activating factor, GAF), P54130; FGF-10, 2911146; FGF-11 (FGF homologous factor 3, FHF-3), Q92914; FGF-12 (FGF homologous factor 1, FHF-1), Q92912; FGF-13 (FGF homologous factor 2, FHF-2), Q92913; FGF-14 (FGF homologous factor 4, FHF-4), Q92915; FGF-15, 2257959; FGF-16, 2911170; FGF-17, 3041790; and FGF-18, 3355904.