RNA splicing: What has phosphorylation got to do with it? - PubMed (original) (raw)
Review
. 1999 Mar 25;9(6):R198-200.
doi: 10.1016/s0960-9822(99)80128-6.
Affiliations
- PMID: 10209090
- DOI: 10.1016/s0960-9822(99)80128-6
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Review
RNA splicing: What has phosphorylation got to do with it?
T Misteli. Curr Biol. 1999.
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Abstract
Many pre-mRNA splicing factors are phosphorylated in vivo, but the role of this modification has been unclear. Recent observations suggest that phosphorylation modulates protein-protein interactions within the spliceosome, thereby contributing to dynamic structural reorganization of the spliceosome during splicing.
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