The arrangement and rearrangement of antibody genes - PubMed (original) (raw)

. 1978 Dec;276(5690):790-5.

doi: 10.1038/276790a0.

• PMID: 103004
• DOI: 10.1038/276790a0

The arrangement and rearrangement of antibody genes

J G Seidman et al. Nature. 1978 Dec.

Abstract

Cloned segments of mouse chromosomal DNA provide direct evidence for the somatic rearrangement of kappa variable and constant region genes in antibody producing cells. This rearrangement apparently affects only one member of an allelic pair of light chain genes.

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