Peripheral T cell survival - PubMed (original) (raw)
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Peripheral T cell survival
A A Freitas et al. Curr Opin Immunol. 1999 Apr.
Abstract
T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are not necessary.
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