Dehalogenases applied to industrial-scale biocatalysis - PubMed (original) (raw)
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Dehalogenases applied to industrial-scale biocatalysis
P E Swanson. Curr Opin Biotechnol. 1999 Aug.
Abstract
In the recent past, the development of dehalogenating enzymes for industrial biocatalysis has been limited, but significant advances have been made. Three classes of enzymes have received attention and development: halalkanoic acid dehalogenases (EC 3.8.1.2), hydrogen-halide lyases (EC 4.5.1), and haloalkane dehalogenases (EC 3.8.1). Applications range from the manufacture of chiral intermediates, to recycling of chlorinated byproducts from chemical manufacturing, and selective treatment of process waste streams.
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