Pax 6: mastering eye morphogenesis and eye evolution - PubMed (original) (raw)
Review
Pax 6: mastering eye morphogenesis and eye evolution
W J Gehring et al. Trends Genet. 1999 Sep.
Abstract
Pax 6 genes from various animal phyla are capable of inducing ectopic eye development, indicating that Pax 6 is a master control gene for eye morphogenesis. It is proposed that the various eye-types found in metazoa are derived from a common prototype, monophyletically, by a mechanism called intercalary evolution.
Comment in
- The eye: monophyletic, polyphyletic or perhaps biphyletic?
Meyer-Rochow VB. Meyer-Rochow VB. Trends Genet. 2000 Jun;16(6):244-5. doi: 10.1016/s0168-9525(00)02019-9. Trends Genet. 2000. PMID: 10827449 No abstract available.
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