DNA engineering and its application to nanotechnology - PubMed (original) (raw)

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DNA engineering and its application to nanotechnology

N C Seeman. Trends Biotechnol. 1999 Nov.

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Abstract

The combination of branched DNA molecules and 'sticky' ends creates a powerful molecular assembly kit for structural DNA nanotechnology. Polyhedra, complex topological objects, a nanomechanical device and two-dimensional arrays with programmable surface features have already been produced in this way. Future applications range from macromolecular crystallography and new materials to molecular electronics and DNA-based computation.

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