Risk factors for prostate cancer: results from the Canadian National Enhanced Cancer Surveillance System. The Canadian Cancer Registries Epidemiology Research Group - PubMed (original) (raw)
Risk factors for prostate cancer: results from the Canadian National Enhanced Cancer Surveillance System. The Canadian Cancer Registries Epidemiology Research Group
P J Villeneuve et al. Cancer Causes Control. 1999 Oct.
Abstract
Objectives: To evaluate the relationship between prostate cancer and several potential lifestyle risk factors.
Methods: We analyzed data obtained from a population-based case-control study conducted in eight Canadian provinces. Risk estimates were generated by applying multivariate logistic regression methods to 1623 histologically confirmed prostate cancer cases and 1623 male controls aged 50-74.
Results: Cases were more likely to have a first-degree relative with a history of cancer, particularly prostate cancer (OR = 3.1, 95% CI = 1.8-5.4). Reduced risks of prostate cancer were observed among those of Indian descent (OR = 0.2, 95% CI = 0.1-0.5) or any Asian descent (OR = 0.3, 95% CI = 0.2-0.6) relative to those of western European descent. Total fat consumption, tomato and energy intake, were not associated with prostate cancer. The risk of prostate cancer was inversely related to the number of cigarettes smoked daily (p = 0.06) and cigarette pack-years (p < 0.01), while no association was observed between the total number of smoking years or the number of years since smoking cessation. Anthropometric measures and moderate and strenuous levels of leisure time physical activity were not strongly related to prostate cancer. In contrast, strenuous occupational activities at younger ages appeared protective.
Conclusions: Our analyses are limited by the absence of data related to tumor severity and screening history. Further studies are needed to investigate the relationship between behavioral risk factors and prostate cancer screening practices.
Similar articles
- Occupation and risk of prostate cancer in Canadian men: A case-control study across eight Canadian provinces.
Sritharan J, Demers PA, Harris SA, Cole DC, Peters CE; Canadian Cancer Registries Epidemiology Research Group; Villeneuve PJ. Sritharan J, et al. Cancer Epidemiol. 2017 Jun;48:96-103. doi: 10.1016/j.canep.2017.04.006. Epub 2017 Apr 26. Cancer Epidemiol. 2017. PMID: 28456092 - Lifestyle and anthropometric risk factors for prostate cancer in a cohort of Iowa men.
Putnam SD, Cerhan JR, Parker AS, Bianchi GD, Wallace RB, Cantor KP, Lynch CF. Putnam SD, et al. Ann Epidemiol. 2000 Aug;10(6):361-9. doi: 10.1016/s1047-2797(00)00057-0. Ann Epidemiol. 2000. PMID: 10964002 - Vasectomy and prostate cancer: a case-control study in India.
Platz EA, Yeole BB, Cho E, Jussawalla DJ, Giovannucci E, Ascherio A. Platz EA, et al. Int J Epidemiol. 1997 Oct;26(5):933-8. doi: 10.1093/ije/26.5.933. Int J Epidemiol. 1997. PMID: 9363512 - Smoking habits and prostate cancer: a case-control study in northern Italy.
Talamini R, Franceschi S, La Vecchia C, Guarneri S, Negri E. Talamini R, et al. Prev Med. 1993 May;22(3):400-8. doi: 10.1006/pmed.1993.1033. Prev Med. 1993. PMID: 8327420 Review. - Prostate cancer: is it time to expand the research focus to early-life exposures?
Sutcliffe S, Colditz GA. Sutcliffe S, et al. Nat Rev Cancer. 2013 Mar;13(3):208-518. doi: 10.1038/nrc3434. Epub 2013 Jan 31. Nat Rev Cancer. 2013. PMID: 23363989 Free PMC article. Review.
Cited by
- Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density.
Langsetmo L, Poliquin S, Hanley DA, Prior JC, Barr S, Anastassiades T, Towheed T, Goltzman D, Kreiger N; CaMos Research Group. Langsetmo L, et al. BMC Musculoskelet Disord. 2010 Jan 28;11:20. doi: 10.1186/1471-2474-11-20. BMC Musculoskelet Disord. 2010. PMID: 20109205 Free PMC article. - Tea and cancer prevention: epidemiological studies.
Yuan JM, Sun C, Butler LM. Yuan JM, et al. Pharmacol Res. 2011 Aug;64(2):123-35. doi: 10.1016/j.phrs.2011.03.002. Epub 2011 Mar 23. Pharmacol Res. 2011. PMID: 21419224 Free PMC article. Review. - Xeno-oestrogens and phyto-oestrogens are alternative ligands for the androgen receptor.
Wang H, Li J, Gao Y, Xu Y, Pan Y, Tsuji I, Sun ZJ, Li XM. Wang H, et al. Asian J Androl. 2010 Jul;12(4):535-47. doi: 10.1038/aja.2010.14. Epub 2010 May 3. Asian J Androl. 2010. PMID: 20436506 Free PMC article. - A Pooled Analysis of 15 Prospective Cohort Studies on the Association between Fruit, Vegetable, and Mature Bean Consumption and Risk of Prostate Cancer.
Petimar J, Wilson KM, Wu K, Wang M, Albanes D, van den Brandt PA, Cook MB, Giles GG, Giovannucci EL, Goodman GE, Goodman PJ, Håkansson N, Helzlsouer K, Key TJ, Kolonel LN, Liao LM, Männistö S, McCullough ML, Milne RL, Neuhouser ML, Park Y, Platz EA, Riboli E, Sawada N, Schenk JM, Tsugane S, Verhage B, Wang Y, Wilkens LR, Wolk A, Ziegler RG, Smith-Warner SA. Petimar J, et al. Cancer Epidemiol Biomarkers Prev. 2017 Aug;26(8):1276-1287. doi: 10.1158/1055-9965.EPI-16-1006. Epub 2017 Apr 26. Cancer Epidemiol Biomarkers Prev. 2017. PMID: 28446545 Free PMC article. - Tomato consumption and prostate cancer risk: a systematic review and meta-analysis.
Xu X, Li J, Wang X, Wang S, Meng S, Zhu Y, Liang Z, Zheng X, Xie L. Xu X, et al. Sci Rep. 2016 Nov 14;6:37091. doi: 10.1038/srep37091. Sci Rep. 2016. PMID: 27841367 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical