The identification of vaginal Lactobacillus species and the demographic and microbiologic characteristics of women colonized by these species - PubMed (original) (raw)

. 1999 Dec;180(6):1950-6.

doi: 10.1086/315109.

Affiliations

• PMID: 10558952
• DOI: 10.1086/315109

The identification of vaginal Lactobacillus species and the demographic and microbiologic characteristics of women colonized by these species

M A Antonio et al. J Infect Dis. 1999 Dec.

Abstract

Lactobacillus acidophilus has been reported to be the predominant vaginal species. Vaginal lactobacilli isolated from 215 sexually active women were identified using whole-chromosomal DNA probes to 20 American Type Culture Collection Lactobacillus strains. Most women were colonized by L. crispatus (32%), followed by L. jensenii (23%), a previously undescribed species designated L. 1086V (15%), L. gasseri (5%), L. fermentum (0.3%), L. oris (0.3%), L. reuteri (0.3%), L. ruminis (0.3%), and L. vaginalis (0.3%). H2O2 was produced by 95% of L. crispatus and 94% of L. jensenii isolates, compared with only 9% of L. 1086V. Colonization by L. crispatus or L. jensenii was positively associated with being white (P<.001), age >/=20 years (P=.05), barrier contraceptive usage (P=.008), and lower frequency of bacterial vaginosis (P<.001) and gonorrhea (P=.03). L. crispatus and L. jensenii, not L. acidophilus, are the most common species of vaginal lactobacilli.

PubMed Disclaimer

Similar articles

• Colonization of the rectum by Lactobacillus species and decreased risk of bacterial vaginosis.
  Antonio MA, Rabe LK, Hillier SL. Antonio MA, et al. J Infect Dis. 2005 Aug 1;192(3):394-8. doi: 10.1086/430926. Epub 2005 Jun 28. J Infect Dis. 2005. PMID: 15995952
• Factors associated with acquisition of, or persistent colonization by, vaginal lactobacilli: role of hydrogen peroxide production.
  Vallor AC, Antonio MA, Hawes SE, Hillier SL. Vallor AC, et al. J Infect Dis. 2001 Dec 1;184(11):1431-6. doi: 10.1086/324445. Epub 2001 Oct 30. J Infect Dis. 2001. PMID: 11709785
• Hydrogen peroxide production and resistance to nonoxinol-9 in Lactobacillus spp. isolated from the vagina of reproductive-age women.
  Angeles-López M, García-Cano Ramos E, Aquino Santiago C. Angeles-López M, et al. Rev Latinoam Microbiol. 2001 Oct-Dec;43(4):171-6. Rev Latinoam Microbiol. 2001. PMID: 17061505
• [The bacterial vaginosis--treatment problems].
  Romanik MK, Ekiel AM, Tomana L, Martirosian G. Romanik MK, et al. Wiad Lek. 2007;60(1-2):64-7. Wiad Lek. 2007. PMID: 17607971 Review. Polish.
• Cutting edge: the vaginal microflora and bacterial vaginosis.
  Verstraelen H. Verstraelen H. Verh K Acad Geneeskd Belg. 2008;70(3):147-74. Verh K Acad Geneeskd Belg. 2008. PMID: 18669158 Review.

Cited by

• Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis.
  Aldunate M, Srbinovski D, Hearps AC, Latham CF, Ramsland PA, Gugasyan R, Cone RA, Tachedjian G. Aldunate M, et al. Front Physiol. 2015 Jun 2;6:164. doi: 10.3389/fphys.2015.00164. eCollection 2015. Front Physiol. 2015. PMID: 26082720 Free PMC article. Review.
• Plasmid transduction using bacteriophage Phi(adh) for expression of CC chemokines by Lactobacillus gasseri ADH.
  Damelin LH, Mavri-Damelin D, Klaenhammer TR, Tiemessen CT. Damelin LH, et al. Appl Environ Microbiol. 2010 Jun;76(12):3878-85. doi: 10.1128/AEM.00139-10. Epub 2010 Apr 23. Appl Environ Microbiol. 2010. PMID: 20418431 Free PMC article.
• Developing animal models for polymicrobial diseases.
  Bakaletz LO. Bakaletz LO. Nat Rev Microbiol. 2004 Jul;2(7):552-68. doi: 10.1038/nrmicro928. Nat Rev Microbiol. 2004. PMID: 15197391 Free PMC article. Review.
• Improved understanding of the bacterial vaginal microbiota of women before and after probiotic instillation.
  Burton JP, Cadieux PA, Reid G. Burton JP, et al. Appl Environ Microbiol. 2003 Jan;69(1):97-101. doi: 10.1128/AEM.69.1.97-101.2003. Appl Environ Microbiol. 2003. PMID: 12513982 Free PMC article.
• Compositional and Functional Differences between Microbiota and Cervical Carcinogenesis as Identified by Shotgun Metagenomic Sequencing.
  Kwon M, Seo SS, Kim MK, Lee DO, Lim MC. Kwon M, et al. Cancers (Basel). 2019 Mar 5;11(3):309. doi: 10.3390/cancers11030309. Cancers (Basel). 2019. PMID: 30841606 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Ovid Technologies, Inc.
  • Silverchair Information Systems

• Other Literature Sources

  • The Lens - Patent Citations Database