End-stage renal failure in type 2 diabetes: A medical catastrophe of worldwide dimensions - PubMed (original) (raw)
Review
End-stage renal failure in type 2 diabetes: A medical catastrophe of worldwide dimensions
E Ritz et al. Am J Kidney Dis. 1999 Nov.
Abstract
The incidence of patients with end-stage renal failure and diabetes mellitus type 2 as a comorbid condition has increased progressively in the past decades, first in the United States and Japan, but subsequently in all countries with a western lifestyle. Although there are explanations for this increase, the major factor is presumably diminishing mortality from hypertension and cardiovascular causes, so that patients survive long enough to develop nephropathy and end-stage renal failure. This review summarizes the striking differences between countries against the background of a similar tendency of an increasing incidence in all countries. Survival on renal replacement therapy continues to be substantially worse for patients with type 2 diabetes. A major reason for this observation is that patients enter renal replacement programs with cardiovascular morbidity acquired in the preterminal phase of renal failure. It is argued that the challenge for the future will be better patient management in earlier phases of diabetic nephropathy to attenuate or prevent progression, as well as cardiovascular complications.
Similar articles
- Nephropathy in type II diabetes.
Ritz E. Ritz E. Exp Clin Endocrinol Diabetes. 1997;105 Suppl 2:80-2. doi: 10.1055/s-0029-1211805. Exp Clin Endocrinol Diabetes. 1997. PMID: 9288553 Review. - [Incidence and clinical characteristics of renal insufficiency in diabetic patients].
Schwenger V, Müssig C, Hergesell O, Zeier M, Ritz E. Schwenger V, et al. Dtsch Med Wochenschr. 2001 Nov 23;126(47):1322-6. doi: 10.1055/s-2001-18564. Dtsch Med Wochenschr. 2001. PMID: 11719856 German. - [Pre-occupying increase in diabetes as cause for terminal kidney failure. Evaluation of treatment strategies].
Pérez García R, Rodríguez Benítez P, Dall'Anesse C, Gómez Campderá F, Valderrábano F. Pérez García R, et al. An Med Interna. 2001 Apr;18(4):175-80. An Med Interna. 2001. PMID: 11496535 Spanish. - How can we improve prognosis in diabetic patients with end-stage renal disease?
Ritz E, Koch M, Fliser D, Schwenger V. Ritz E, et al. Diabetes Care. 1999 Mar;22 Suppl 2:B80-3. Diabetes Care. 1999. PMID: 10097905 Review.
Cited by
- Signalment and laboratory findings in cats with diabetes mellitus in Germany: a retrospective review of laboratory submissions of 129,505 cats.
Guse B, Langenstein J, Bauer N, Hazuchova K. Guse B, et al. J Feline Med Surg. 2024 Sep;26(9):1098612X241262669. doi: 10.1177/1098612X241262669. J Feline Med Surg. 2024. PMID: 39286966 Free PMC article. - Education programmes for people with chronic kidney disease and diabetes.
Cashmore BA, Cooper TE, Evangelidis NM, Green SC, Lopez-Vargas P, Tunnicliffe DJ. Cashmore BA, et al. Cochrane Database Syst Rev. 2024 Aug 22;8(8):CD007374. doi: 10.1002/14651858.CD007374.pub3. Cochrane Database Syst Rev. 2024. PMID: 39171639 Review. - Causal relationship between gut microbiota and diabetic nephropathy: a two-sample Mendelian randomization study.
Yan S, Wang H, Feng B, Ye L, Chen A. Yan S, et al. Front Immunol. 2024 Mar 8;15:1332757. doi: 10.3389/fimmu.2024.1332757. eCollection 2024. Front Immunol. 2024. PMID: 38533501 Free PMC article. - The Role of G Protein-Coupled Receptors and Receptor Kinases in Pancreatic _β_-Cell Function and Diabetes.
Varney MJ, Benovic JL. Varney MJ, et al. Pharmacol Rev. 2024 Feb 13;76(2):267-299. doi: 10.1124/pharmrev.123.001015. Pharmacol Rev. 2024. PMID: 38351071 Free PMC article. Review. - Screening immune-related blood biomarkers for DKD-related HCC using machine learning.
Chen C, Xie Z, Ni Y, He Y. Chen C, et al. Front Immunol. 2024 Jan 22;15:1339373. doi: 10.3389/fimmu.2024.1339373. eCollection 2024. Front Immunol. 2024. PMID: 38318171 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous