Bunyavirus superinfection and segment reassortment in transovarially infected mosquitoes - PubMed (original) (raw)
Bunyavirus superinfection and segment reassortment in transovarially infected mosquitoes
Monica K Borucki et al. J Gen Virol. 1999 Dec.
Abstract
Rapid evolution of bunyaviruses may occur by RNA segment reassortment between closely related viruses. Reassortment between viruses occurs in dually infected mosquitoes when two different viruses are simultaneously ingested or when the second virus is ingested within 2 days of the first virus. By 3 days after oral infection, interference to superinfection occurs, thus limiting the potential for evolution. Aedes triseriatus mosquitoes can also be transovarially infected (TI+) with LaCrosse (LAC) virus. In these studies, the potential for oral superinfection of TI+ mosquitoes was assessed. Approximately 20% of mosquitoes TI+ with either a temperature-sensitive LAC virus or wild-type (wt) LAC virus became superinfected by ingesting blood meals containing wt LAC or snowshoe hare (SSH) viruses. LAC virus TI+ mosquitoes superinfected with SSH virus were detected by blot hybridization or RT-PCR. Viruses from these mosquitoes were plaque purified and genotyped using RT-PCR. Reassortant genomes were detected in 2.3% of the viruses genotyped, and 4.0% of the genomes tested were diploid for one genome segment.
Similar articles
- Heterologous reassortment of bunyaviruses in Aedes triseriatus mosquitoes and transovarial and oral transmission of newly evolved genotypes.
Chandler LJ, Beaty BJ, Baldridge GD, Bishop DH, Hewlett MJ. Chandler LJ, et al. J Gen Virol. 1990 May;71 ( Pt 5):1045-50. doi: 10.1099/0022-1317-71-5-1045. J Gen Virol. 1990. PMID: 2345365 - Molecular basis of bunyavirus per os infection of mosquitoes: role of the middle-sized RNA segment.
Beaty BJ, Miller BR, Shope RE, Rozhon EJ, Bishop DH. Beaty BJ, et al. Proc Natl Acad Sci U S A. 1982 Feb;79(4):1295-7. doi: 10.1073/pnas.79.4.1295. Proc Natl Acad Sci U S A. 1982. PMID: 6951175 Free PMC article. - Bunyavirus-vector interactions.
Beaty BJ, Bishop DH. Beaty BJ, et al. Virus Res. 1988 Jun;10(4):289-301. doi: 10.1016/0168-1702(88)90071-8. Virus Res. 1988. PMID: 3046165 Review. - The role of mosquitoes in the natural history of California serogroup viruses.
Turell MJ, LeDuc JW. Turell MJ, et al. Prog Clin Biol Res. 1983;123:43-55. Prog Clin Biol Res. 1983. PMID: 6135223 Review.
Cited by
- Taxonomy of Phleboviruses, Emphasizing Those That Are Sandfly-Borne.
Calisher CH, Calzolari M. Calisher CH, et al. Viruses. 2021 May 15;13(5):918. doi: 10.3390/v13050918. Viruses. 2021. PMID: 34063467 Free PMC article. - Evolutionary influences in arboviral disease.
Weaver SC. Weaver SC. Curr Top Microbiol Immunol. 2006;299:285-314. doi: 10.1007/3-540-26397-7_10. Curr Top Microbiol Immunol. 2006. PMID: 16568903 Free PMC article. Review. - Insect-specific virus evolution and potential effects on vector competence.
Öhlund P, Lundén H, Blomström AL. Öhlund P, et al. Virus Genes. 2019 Apr;55(2):127-137. doi: 10.1007/s11262-018-01629-9. Epub 2019 Jan 10. Virus Genes. 2019. PMID: 30632016 Free PMC article. Review. - Bunyavirus-vector interactions.
Horne KM, Vanlandingham DL. Horne KM, et al. Viruses. 2014 Nov 13;6(11):4373-97. doi: 10.3390/v6114373. Viruses. 2014. PMID: 25402172 Free PMC article. Review. - Applications of quantitative PCR in the biosafety and genetic stability assessment of biotechnology products.
Lovatt A. Lovatt A. J Biotechnol. 2002 Jan;82(3):279-300. doi: 10.1016/s1389-0352(01)00043-5. J Biotechnol. 2002. PMID: 11999695 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Miscellaneous