LIGAND: chemical database of enzyme reactions - PubMed (original) (raw)
LIGAND: chemical database of enzyme reactions
S Goto et al. Nucleic Acids Res. 2000.
Abstract
LIGAND is a composite database comprising three sections: ENZYME for the information of enzyme molecules and enzymatic reactions, COMPOUND for the information of metabolites and other chemical compounds, and REACTION for the collection of substrate-product relations. The current release includes 3390 enzymes, 5645 compounds and 5207 reactions. The database is indispensable for the reconstruction of metabolic pathways in the completely sequenced organisms. The LIGAND database can be accessed through the WWW (http://www.genome.ad.jp/dbget/ligand.html ) or may be downloaded by anonymous FTP (ftp://kegg.genome.ad.jp/molecules/ligand/ ).
Similar articles
- LIGAND: database of chemical compounds and reactions in biological pathways.
Goto S, Okuno Y, Hattori M, Nishioka T, Kanehisa M. Goto S, et al. Nucleic Acids Res. 2002 Jan 1;30(1):402-4. doi: 10.1093/nar/30.1.402. Nucleic Acids Res. 2002. PMID: 11752349 Free PMC article. - LIGAND database for enzymes, compounds and reactions.
Goto S, Nishioka T, Kanehisa M. Goto S, et al. Nucleic Acids Res. 1999 Jan 1;27(1):377-9. doi: 10.1093/nar/27.1.377. Nucleic Acids Res. 1999. PMID: 9847234 Free PMC article. - LIGAND: chemical database for enzyme reactions.
Goto S, Nishioka T, Kanehisa M. Goto S, et al. Bioinformatics. 1998;14(7):591-9. doi: 10.1093/bioinformatics/14.7.591. Bioinformatics. 1998. PMID: 9730924 - The KEGG database.
Kanehisa M. Kanehisa M. Novartis Found Symp. 2002;247:91-101; discussion 101-3, 119-28, 244-52. Novartis Found Symp. 2002. PMID: 12539951 Review. - BRENDA: a resource for enzyme data and metabolic information.
Schomburg I, Chang A, Hofmann O, Ebeling C, Ehrentreich F, Schomburg D. Schomburg I, et al. Trends Biochem Sci. 2002 Jan;27(1):54-6. doi: 10.1016/s0968-0004(01)02027-8. Trends Biochem Sci. 2002. PMID: 11796225 Review.
Cited by
- Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome.
Casero D, Gill K, Sridharan V, Koturbash I, Nelson G, Hauer-Jensen M, Boerma M, Braun J, Cheema AK. Casero D, et al. Microbiome. 2017 Aug 18;5(1):105. doi: 10.1186/s40168-017-0325-z. Microbiome. 2017. PMID: 28821301 Free PMC article. - Constraint and Contingency Pervade the Emergence of Novel Phenotypes in Complex Metabolic Systems.
Hosseini SR, Wagner A. Hosseini SR, et al. Biophys J. 2017 Aug 8;113(3):690-701. doi: 10.1016/j.bpj.2017.06.034. Biophys J. 2017. PMID: 28793223 Free PMC article. - Phenotypic innovation through recombination in genome-scale metabolic networks.
Hosseini SR, Martin OC, Wagner A. Hosseini SR, et al. Proc Biol Sci. 2016 Sep 28;283(1839):20161536. doi: 10.1098/rspb.2016.1536. Proc Biol Sci. 2016. PMID: 27683361 Free PMC article. - Exhaustive Analysis of a Genotype Space Comprising 10(15 )Central Carbon Metabolisms Reveals an Organization Conducive to Metabolic Innovation.
Hosseini SR, Barve A, Wagner A. Hosseini SR, et al. PLoS Comput Biol. 2015 Aug 7;11(8):e1004329. doi: 10.1371/journal.pcbi.1004329. eCollection 2015 Aug. PLoS Comput Biol. 2015. PMID: 26252881 Free PMC article. - Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms.
Barve A, Hosseini SR, Martin OC, Wagner A. Barve A, et al. BMC Syst Biol. 2014 Apr 23;8:48. doi: 10.1186/1752-0509-8-48. BMC Syst Biol. 2014. PMID: 24758311 Free PMC article.
References
- Goto S., Nishioka,T. and Kanehisa,M. (1998) Bioinformatics, 14, 591–599. - PubMed
- Kanehisa M. (1997) Trends Genet., 13, 375–376. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources