Predictive factors in prostate cancer: current concepts from the 1999 College of American Pathologists Conference on Solid Tumor Prognostic Factors and the 1999 World Health Organization Second International Consultation on Prostate Cancer - PubMed (original) (raw)

Affiliations

PMID: 10632123

Review

Predictive factors in prostate cancer: current concepts from the 1999 College of American Pathologists Conference on Solid Tumor Prognostic Factors and the 1999 World Health Organization Second International Consultation on Prostate Cancer

D G Bostwick et al. Semin Urol Oncol. 1999 Nov.

Abstract

Many clinically important predictive factors in prostate cancer are derived from light microscopic examination of tissue specimens by the pathologist. Two separate international consensus conferences held in 1999 addressed the contemporary status of such prognostic factors, sponsored by the College of American Pathologists (CAP) and the World Health Organization (WHO). Both conferences concluded that the following factors are recommended for routine use based on evidence from multiple published trials: TNM stage, histological grade using the Gleason system, surgical margin status, and serum prostate-specific antigen concentration. The WHO conference additionally recommended use of WHO nuclear grade, location of cancer within the prostate, and pathological effects of treatment. Other factors were categorized as promising or of unproven utility, including a wide variety of histopathologic and genetic markers. Standards are needed for analysis and quantitation of methods of tissue analysis, particularly for immunohistochemical studies and genotypic studies. This report describes the recommendations and conclusions of these two conferences.

PubMed Disclaimer

Cited by

Comparison of Diffusion Kurtosis Imaging and Amide Proton Transfer Imaging in the Diagnosis and Risk Assessment of Prostate Cancer.
Yin H, Wang D, Yan R, Jin X, Hu Y, Zhai Z, Duan J, Zhang J, Wang K, Han D. Yin H, et al. Front Oncol. 2021 Apr 15;11:640906. doi: 10.3389/fonc.2021.640906. eCollection 2021. Front Oncol. 2021. PMID: 33937041 Free PMC article.
Models predicting survival to guide treatment decision-making in newly diagnosed primary non-metastatic prostate cancer: a systematic review.
Thurtle D, Rossi SH, Berry B, Pharoah P, Gnanapragasam VJ. Thurtle D, et al. BMJ Open. 2019 Jun 22;9(6):e029149. doi: 10.1136/bmjopen-2019-029149. BMJ Open. 2019. PMID: 31230029 Free PMC article.
Individual prognosis at diagnosis in nonmetastatic prostate cancer: Development and external validation of the PREDICT Prostate multivariable model.
Thurtle DR, Greenberg DC, Lee LS, Huang HH, Pharoah PD, Gnanapragasam VJ. Thurtle DR, et al. PLoS Med. 2019 Mar 12;16(3):e1002758. doi: 10.1371/journal.pmed.1002758. eCollection 2019 Mar. PLoS Med. 2019. PMID: 30860997 Free PMC article.
Correlations Between Intratumoral Interstitial Fibrillary Network and Vascular Network in Gleason Patterns of Prostate Adenocarcinoma.
Pleșea RM, Șerbănescu MS, Alexandru DO, Ciovică V, Stoiculescu A, Pop OT, Simionescu C, Pleșea IE. Pleșea RM, et al. Curr Health Sci J. 2015 Oct-Dec;41(4):345-355. doi: 10.12865/CHSJ.41.04.09. Epub 2015 Dec 22. Curr Health Sci J. 2015. PMID: 30538841 Free PMC article.
Androgen Receptor Expression in Epithelial and Stromal Cells of Prostatic Carcinoma and Benign Prostatic Hyperplasia.
Filipovski V, Kubelka-Sabit K, Jasar D, Janevska V. Filipovski V, et al. Open Access Maced J Med Sci. 2017 Aug 5;5(5):608-612. doi: 10.3889/oamjms.2017.151. eCollection 2017 Aug 15. Open Access Maced J Med Sci. 2017. PMID: 28932300 Free PMC article.

Predictive factors in prostate cancer: current concepts from the 1999 College of American Pathologists Conference on Solid Tumor Prognostic Factors and the 1999 World Health Organization Second International Consultation on Prostate Cancer - PubMed (original) (raw)