Melatonin treatment of winter depression: a pilot study - PubMed (original) (raw)

Clinical Trial

Melatonin treatment of winter depression: a pilot study

A J Lewy et al. Psychiatry Res. 1998.

Abstract

Five patients with winter depression received low doses of melatonin in the afternoon, and five patients received placebo capsules. Melatonin treatment significantly decreased depression ratings compared to placebo. If these findings are replicated in a larger sample with documentation of expected phase shifts, the phase shift hypothesis will be substantially supported.

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