The age-range of risk of developing multiple sclerosis: evidence from a migrant population in Australia - PubMed (original) (raw)
. 2000 May:123 ( Pt 5):968-74.
doi: 10.1093/brain/123.5.968.
Affiliations
- PMID: 10775541
- DOI: 10.1093/brain/123.5.968
The age-range of risk of developing multiple sclerosis: evidence from a migrant population in Australia
S R Hammond et al. Brain. 2000 May.
Abstract
The prevalence of multiple sclerosis in the Australian-born population in five different regions of Australia has a strong correlation with latitude, the disease becoming increasingly prevalent with increasing south latitude. In this study, the prevalence in the migrant population from the UK and Ireland (UKI) in the different regions also showed a significant correlation with latitude, but this relationship was strongly influenced by the high prevalence in Hobart. Except for Hobart, the prevalence in migrants was considerably less than that in their countries of origin. The prevalence of multiple sclerosis among those migrating before the age of 15 years from the high-risk UKI to lower-risk Australia was not significantly different to that among those migrating at or after that age, and this finding was confirmed in a case-control study which demonstrated little association between age at migration and risk of developing multiple sclerosis. These findings suggest that the risk from environmental factors in multiple sclerosis may operate over a period of many years and not only in childhood and early adult life.
Similar articles
- The epidemiology of multiple sclerosis in three Australian cities: Perth, Newcastle and Hobart.
Hammond SR, McLeod JG, Millingen KS, Stewart-Wynne EG, English D, Holland JT, McCall MG. Hammond SR, et al. Brain. 1988 Feb;111 ( Pt 1):1-25. doi: 10.1093/brain/111.1.1. Brain. 1988. PMID: 3365543 - Migration and multiple sclerosis in immigrants to Australia from United Kingdom and Ireland: a reassessment. I. Risk of MS by age at immigration.
McLeod JG, Hammond SR, Kurtzke JF. McLeod JG, et al. J Neurol. 2011 Jun;258(6):1140-9. doi: 10.1007/s00415-010-5898-4. Epub 2011 Jan 25. J Neurol. 2011. PMID: 21264474 Free PMC article. - Migrant studies in multiple sclerosis.
Gale CR, Martyn CN. Gale CR, et al. Prog Neurobiol. 1995 Nov-Dec;47(4-5):425-48. Prog Neurobiol. 1995. PMID: 8966212 Review. - Multiple sclerosis in migrant populations.
Alter M. Alter M. Triangle. 1973;12(1):25-30. Triangle. 1973. PMID: 4577559 Review. No abstract available.
Cited by
- Epithelial Barrier Theory: The Role of Exposome, Microbiome, and Barrier Function in Allergic Diseases.
Losol P, Sokolowska M, Hwang YK, Ogulur I, Mitamura Y, Yazici D, Pat Y, Radzikowska U, Ardicli S, Yoon JE, Choi JP, Kim SH, van de Veen W, Akdis M, Chang YS, Akdis CA. Losol P, et al. Allergy Asthma Immunol Res. 2023 Nov;15(6):705-724. doi: 10.4168/aair.2023.15.6.705. Allergy Asthma Immunol Res. 2023. PMID: 37957791 Free PMC article. Review. - Multi-Criterial Model for Weighting Biological Risk Factors in Multiple Sclerosis: Clinical and Health Insurance Implications.
De Masi R, Orlando S, Leo C, Pasca M, Anzilli L, Costa MC. De Masi R, et al. Healthcare (Basel). 2023 Aug 29;11(17):2420. doi: 10.3390/healthcare11172420. Healthcare (Basel). 2023. PMID: 37685453 Free PMC article. - Spatial and Ecological Factors Modulate the Incidence of Anti-NMDAR Encephalitis-A Systematic Review.
Alentorn A, Berzero G, Alexopoulos H, Tzartos J, Reyes Botero G, Morales Martínez A, Muñiz-Castrillo S, Vogrig A, Joubert B, García Jiménez FA, Cabrera D, Tobon JV, Delgado C, Sandoval P, Troncoso M, Galleguillos L, Giry M, Benazra M, Hernández Verdin I, Dade M, Picard G, Rogemond V, Weiss N, Dalakas MC, Boëlle PY, Delattre JY, Honnorat J, Psimaras D. Alentorn A, et al. Biomedicines. 2023 May 25;11(6):1525. doi: 10.3390/biomedicines11061525. Biomedicines. 2023. PMID: 37371620 Free PMC article. Review. - Medical Applications of Molecular Biotechnologies in the Context of Hashimoto's Thyroiditis.
Trovato M, Valenti A. Trovato M, et al. Diagnostics (Basel). 2023 Jun 19;13(12):2114. doi: 10.3390/diagnostics13122114. Diagnostics (Basel). 2023. PMID: 37371008 Free PMC article. Review. - Epithelial Barrier Hypothesis and Its Comparison with the Hygiene Hypothesis.
Kıykım A, Öğülür İ, Yazıcı D, Çokuğraş H, Akdiş M, Akdiş CA. Kıykım A, et al. Turk Arch Pediatr. 2023 Mar;58(2):122-128. doi: 10.5152/TurkArchPediatr.2023.23006. Turk Arch Pediatr. 2023. PMID: 36856348 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical