Single-molecule studies of DNA mechanics - PubMed (original) (raw)

Single-molecule studies of DNA mechanics

C Bustamante et al. Curr Opin Struct Biol. 2000 Jun.

Abstract

During the past decade, physical techniques such as optical tweezers and atomic force microscopy were used to study the mechanical properties of DNA at the single-molecule level. Knowledge of DNA's stretching and twisting properties now permits these single-molecule techniques to be used in the study of biological processes such as DNA replication and transcription.

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