Antitumor effect of anthocyanin fractions extracted from red soybeans and red beans in vitro and in vivo - PubMed (original) (raw)
Antitumor effect of anthocyanin fractions extracted from red soybeans and red beans in vitro and in vivo
T Koide et al. Cancer Biother Radiopharm. 1997 Aug.
Abstract
Many bioflavonoids extracted from petals of higher plants and from fruit rinds, as well as purified flavonoids, have been reported to have antitumor effects in vitro and in vivo. Bioflavonoids extracted from red soybeans are mostly cyanin conjugated with glucose and rhamnose, whereas bioflavonoids of red beans are cyanin conjugated with rhamnose as revealed by thin-layer chromatogram. Flavonoids extracted from red soybeans were effective in inhibiting the growth of HCT-15 cells in vitro. On the other hand, flavonoids from red beans were not effective, although their hydrolyzed sugar-free forms were growth inhibitory. Sugar-bonded bioflavonoids extracted from both red soybeans and red beans were effective in prolonging the survival of Balb/C mice bearing syngeneic tumor-Meth/A cells, when they were dissolved in drinking water and given at a dose of approximately 500 micrograms/mouse/day.
Similar articles
- Antitumor effect of hydrolyzed anthocyanin from grape rinds and red rice.
Koide T, Kamei H, Hashimoto Y, Kojima T, Hasegawa M. Koide T, et al. Cancer Biother Radiopharm. 1996 Aug;11(4):273-7. doi: 10.1089/cbr.1996.11.273. Cancer Biother Radiopharm. 1996. PMID: 10851548 - Flavonoid-mediated tumor growth suppression demonstrated by in vivo study.
Kamei H, Koide T, Kojimam T, Hasegawa M, Terabe K, Umeda T, Hashimoto Y. Kamei H, et al. Cancer Biother Radiopharm. 1996 Jun;11(3):193-6. doi: 10.1089/cbr.1996.11.193. Cancer Biother Radiopharm. 1996. PMID: 10851537 - Suppression of tumor cell growth by anthocyanins in vitro.
Kamei H, Kojima T, Hasegawa M, Koide T, Umeda T, Yukawa T, Terabe K. Kamei H, et al. Cancer Invest. 1995;13(6):590-4. doi: 10.3109/07357909509024927. Cancer Invest. 1995. PMID: 7583708 - Suppression of growth of cultured malignant cells by allomelanins, plant-produced melanins.
Kamei H, Koide T, Kojima T, Hasegawa M, Umeda T. Kamei H, et al. Cancer Biother Radiopharm. 1997 Feb;12(1):47-9. doi: 10.1089/cbr.1997.12.47. Cancer Biother Radiopharm. 1997. PMID: 10851446
Cited by
- Trichoderma harzianum prevents red kidney bean root rot by increasing plant antioxidant enzyme activity and regulating the rhizosphere microbial community.
Guo Z, Zhang J, Liu Z, Li Y, Li M, Meng Q, Yang Z, Luo Y, Zhang Q, Yan M. Guo Z, et al. Front Microbiol. 2024 Mar 20;15:1348680. doi: 10.3389/fmicb.2024.1348680. eCollection 2024. Front Microbiol. 2024. PMID: 38572240 Free PMC article. - The Extraction and High Antiproliferative Effect of Anthocyanin from Gardenblue Blueberry.
Zhao F, Wang J, Wang W, Lyu L, Wu W, Li W. Zhao F, et al. Molecules. 2023 Mar 22;28(6):2850. doi: 10.3390/molecules28062850. Molecules. 2023. PMID: 36985822 Free PMC article. - Repressive effects of red bean, Phaseolus angularis, extracts on obesity of mouse induced with high-fat diet via downregulation of adipocyte differentiation and modulating lipid metabolism.
Park YM, Kim JI, Seo DH, Seo JH, Lim JH, Lee JE, Choi JY, Seo EW. Park YM, et al. Food Sci Biotechnol. 2018 Jul 7;27(6):1811-1821. doi: 10.1007/s10068-018-0421-2. eCollection 2018 Dec. Food Sci Biotechnol. 2018. PMID: 30483446 Free PMC article. - Combined Effects of Phytochemicals and Exercise on Fatty Acid Oxidation.
Kim JH, Park Y. Kim JH, et al. J Exerc Nutrition Biochem. 2016 Dec 31;20(4):20-26. doi: 10.20463/jenb.2016.0053. J Exerc Nutrition Biochem. 2016. PMID: 28150474 Free PMC article. Review. - Optimization of extraction parameters of PTP1β (protein tyrosine phosphatase 1β), inhibitory polyphenols, and anthocyanins from Zea mays L. using response surface methodology (RSM).
Hwang SH, Kwon SH, Wang Z, Kim TH, Kang YH, Lee JY, Lim SS. Hwang SH, et al. BMC Complement Altern Med. 2016 Aug 26;16(1):317. doi: 10.1186/s12906-016-1296-5. BMC Complement Altern Med. 2016. PMID: 27561370 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources