Cholinesterase in embryonic development - PubMed (original) (raw)
- PMID: 1094493
Review
Cholinesterase in embryonic development
U Drews. Prog Histochem Cytochem. 1975.
Abstract
I. Cholinesterase (ChE) activity was studied histochemically during early development of the sea urchin, the amphibian, the chick and the rat embryo. After formalin fixation and embedding in water-soluble carbowax, the enzyme reaction was carried out in serial section. 2. Independent from innervation ChE appears in every embryonic blastema in a very early stage of development. It disappears from the embryonic cells after they have assembled into definite organ structures. Thus, ChE plays a role in embryonic development which is different from its known function in the adult. Therefore, ChE activity present in differentiating cells during a limited phase of development, is termed "embryonic cholinesterase". 3. Embryonic ChE was invariably found in cells engaged in morphogenetic movements. This observation has led us to suppose that the enzyme in involved in the regulation of cellular movements during development. 4. In particular, embryonic ChE is described in the following locations: a) During sea urchin gastrulation ChE is present in the primary mesenchymal cells emigrating from the blastula wall and in the archenteron cells which are known to bring about the invagination movement by contraction of their pseudopods. b) In the early chick blastoderm ChE active "droplet cells" are described which are supposed to emigrate from the epiblast layer in order to form the hypoblast. c) During development of notochord and somites, during closure of the neural tube and development of the head anlage, the close correlation of ChE activity with various morphogenetic movements is demonstrated: ChE appears during aggregation and desaggregation of epithelial compounds. The active bending of preexisting epithelial sheets, such as the neural plate, is also accompanied by ChE activity in epithelial cells...
Similar articles
- Characterization of the role of cadherin in regulating cell adhesion during sea urchin development.
Miller JR, McClay DR. Miller JR, et al. Dev Biol. 1997 Dec 15;192(2):323-39. doi: 10.1006/dbio.1997.8740. Dev Biol. 1997. PMID: 9441671 - FGF signals guide migration of mesenchymal cells, control skeletal morphogenesis [corrected] and regulate gastrulation during sea urchin development.
Röttinger E, Saudemont A, Duboc V, Besnardeau L, McClay D, Lepage T. Röttinger E, et al. Development. 2008 Jan;135(2):353-65. doi: 10.1242/dev.014282. Epub 2007 Dec 12. Development. 2008. PMID: 18077587 - Patterns of cholinesterase staining during neural crest cell morphogenesis in mouse and chick embryos.
Martins-Green M, Erickson CA. Martins-Green M, et al. J Exp Zool. 1988 Jul;247(1):62-8. doi: 10.1002/jez.1402470109. J Exp Zool. 1988. PMID: 3183585 - Gastrulation in the sea urchin embryo: a model system for analyzing the morphogenesis of a monolayered epithelium.
Kominami T, Takata H. Kominami T, et al. Dev Growth Differ. 2004 Aug;46(4):309-26. doi: 10.1111/j.1440-169x.2004.00755.x. Dev Growth Differ. 2004. PMID: 15367199 Review. - Cell movements in the sea urchin embryo.
Ettensohn CA. Ettensohn CA. Curr Opin Genet Dev. 1999 Aug;9(4):461-5. doi: 10.1016/S0959-437X(99)80070-7. Curr Opin Genet Dev. 1999. PMID: 10449348 Review.
Cited by
- Eco-Interactions of Engineered Nanomaterials in the Marine Environment: Towards an Eco-Design Framework.
Corsi I, Bellingeri A, Eliso MC, Grassi G, Liberatori G, Murano C, Sturba L, Vannuccini ML, Bergami E. Corsi I, et al. Nanomaterials (Basel). 2021 Jul 24;11(8):1903. doi: 10.3390/nano11081903. Nanomaterials (Basel). 2021. PMID: 34443734 Free PMC article. Review. - Multifaceted WNT Signaling at the Crossroads Between Epithelial-Mesenchymal Transition and Autophagy in Glioblastoma.
Coelho BP, Fernandes CFL, Boccacino JM, Souza MCDS, Melo-Escobar MI, Alves RN, Prado MB, Iglesia RP, Cangiano G, Mazzaro GR, Lopes MH. Coelho BP, et al. Front Oncol. 2020 Nov 12;10:597743. doi: 10.3389/fonc.2020.597743. eCollection 2020. Front Oncol. 2020. PMID: 33312955 Free PMC article. Review. - Cancer and Alzheimer's disease inverse relationship: an age-associated diverging derailment of shared pathways.
Lanni C, Masi M, Racchi M, Govoni S. Lanni C, et al. Mol Psychiatry. 2021 Jan;26(1):280-295. doi: 10.1038/s41380-020-0760-2. Epub 2020 May 7. Mol Psychiatry. 2021. PMID: 32382138 Review. - A historic perspective on the current progress in elucidation of the biologic significance of non-neuronal acetylcholine.
Grando SA, Kawashima K, Wessler I. Grando SA, et al. Int Immunopharmacol. 2020 Apr;81:106289. doi: 10.1016/j.intimp.2020.106289. Epub 2020 Feb 26. Int Immunopharmacol. 2020. PMID: 32113128 Free PMC article. - Exploring the mechanisms of graphene oxide behavioral and morphological changes in zebrafish.
Clemente Z, Silva GH, de Souza Nunes MC, Martinez DST, Maurer-Morelli CV, Thomaz AA, Castro VLSS. Clemente Z, et al. Environ Sci Pollut Res Int. 2019 Oct;26(29):30508-30523. doi: 10.1007/s11356-019-05870-z. Epub 2019 Aug 28. Environ Sci Pollut Res Int. 2019. PMID: 31463743
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Miscellaneous