Long-term benefit of extended lymphadenectomy with gastrectomy in distally located early gastric carcinoma - PubMed (original) (raw)
Comparative Study
Long-term benefit of extended lymphadenectomy with gastrectomy in distally located early gastric carcinoma
E Otsuji et al. Am J Surg. 2000 Aug.
Abstract
Background: Extended lymphadenectomy performed with gastrectomy has been reported to prolong survival of patients with early gastric cancer. However, some authors question the value of extensive lymphadenectomy in these patients, especially since much recent discussion of patient quality of life after gastrectomy has favored less invasive operations.
Methods: We retrospectively analyzed 485 patients who had undergone gastrectomy for early cancer in order to evaluate the effect of extended versus limited lymphadenectomy on postoperative survival. Various prognostic factors were examined for patients whose tumors were located in the distal third of the stomach.
Results: Although extended radical lymphadenectomy did not prolong postoperative survival when early gastric cancer was located in the middle or proximal third of the stomach, it did when the tumor occupied the distal third.
Conclusions: Performance of extended radical lymphadenectomy was a significant prognostic factor for early gastric cancer patients when tumors were located in the distal third of the stomach.
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