Upstream open reading frames as regulators of mRNA translation - PubMed (original) (raw)

Review

Upstream open reading frames as regulators of mRNA translation

D R Morris et al. Mol Cell Biol. 2000 Dec.

No abstract available

PubMed Disclaimer

Figures

FIG. 1

FIG. 1

Alternative fates available to a ribosome after translating a uORF. See the text for a detailed discussion.

FIG. 2

FIG. 2

Structures of the leaders of selected mRNAs. uORFs contained in these mRNAs are depicted by the thick horizontal lines.

References

    1. Alderete J P, Jarrahian S, Geballe A P. Translational effects of mutations and polymorphisms in a repressive upstream open reading frame of the human cytomegalovirus UL4 gene. J Virol. 1999;73:8330–8337. - PMC - PubMed
    1. Banks J D, Linial M L. Secondary structure analysis of a minimal avian leukosis-sarcoma virus packaging signal. J Virol. 2000;74:456–464. - PMC - PubMed
    1. Barak Y, Gottlieb E, Juvengershon T, Oren M. Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential. Genes Dev. 1994;8:1739–1749. - PubMed
    1. Brown C Y, Mize G J, Pineda M, George D L, Morris D R. Role of two upstream open reading frames in the translational control of oncogene mdm2. Oncogene. 1999;18:5631–5637. - PubMed
    1. Calkhoven C F, Bouwman P R J, Snippe L, Ab G. Translation start site multiplicity of the CCAAT enhancer binding protein alpha mRNA is dictated by a small 5′ open reading frame. Nucleic Acids Res. 1994;22:5540–5547. - PMC - PubMed

Publication types

MeSH terms

Substances

Grants and funding

LinkOut - more resources