Dendritic arbor development and synaptogenesis - PubMed (original) (raw)

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Dendritic arbor development and synaptogenesis

H T Cline. Curr Opin Neurobiol. 2001 Feb.

Abstract

In vivo studies indicate that synaptic activity promotes dendritic arbor elaboration at early stages of brain development. At later stages of development, synaptic activity stabilizes dendritic structure. The different roles of synaptic activity with respect to structural plasticity probably reflect the regulated spatiotemporal expression of key components within signaling pathways.

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