Control of eukaryotic transcription elongation - PubMed (original) (raw)

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Control of eukaryotic transcription elongation

F Winston. Genome Biol. 2001.

Abstract

The Spt4, Spt5, and Spt6 proteins are conserved eukaryotic transcription-elongation factors. Recent studies have provided the first evidence that they are generally required in multicellular eukaryotes, including during development and for viral gene expression.

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Figures

Figure 1

Colocalization of (a) Spt5 and (b) Spt6 with Pol IIoser2 (Pol IIo phosphorylated on Ser2) on Drosophila polytene chromosomes. Spt5 and Spt6 are red, Pol IIoser2 is green and colocalization is shown as yellow. Polytene positions 74EF and 75B are indicated. Adapted with permission from [12].

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