Expressing the human genome - PubMed (original) (raw)

. 2001 Feb 15;409(6822):832-3.

doi: 10.1038/35057011.

Affiliations

• PMID: 11237001
• DOI: 10.1038/35057011

Expressing the human genome

R Tupler et al. Nature. 2001.

Abstract

We have searched the human genome for genes encoding new proteins that may be involved in three nuclear gene expression processes: transcription, pre-messenger RNA splicing and polyadenylation. A plethora of potential new factors are implicated by sequence in nuclear gene expression, revealing a substantial but selective increase in complexity compared with Drosophila melanogaster and Caenorhabditis elegans. Although the raw genomic information has limitations, its availability offers new experimental approaches for studying gene expression.

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