Orientation preference patterns in mammalian visual cortex: a wire length minimization approach - PubMed (original) (raw)
Orientation preference patterns in mammalian visual cortex: a wire length minimization approach
A A Koulakov et al. Neuron. 2001 Feb.
Free article
Abstract
In the visual cortex of many mammals, orientation preference changes smoothly along the cortical surface, with the exception of singularities such as pinwheels and fractures. The reason for the existence of these singularities has remained elusive, suggesting that they are developmental artifacts. We show that singularities reduce the length of intracortical neuronal connections for some connection rules. Therefore, pinwheels and fractures could be evolutionary adaptations keeping cortical volume to a minimum. Wire length minimization approach suggests that interspecies differences in orientation preference maps reflect differences in intracortical neuronal circuits, thus leading to experimentally testable predictions. We discuss application of our model to direction preference maps.
Comment in
- Keeping the wires short: a singularly difficult problem.
Swindale NV. Swindale NV. Neuron. 2001 Feb;29(2):316-7. doi: 10.1016/s0896-6273(01)00206-9. Neuron. 2001. PMID: 11239423 No abstract available.
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